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Sandrine CHARLES

Professeur des Universités
12
Documents
Affiliations actuelles
  • 194495
  • 10025
  • 543541
Identifiants chercheurs
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Présentation

My research activities focus on quantitative risk assessment in ecotoxicology. This involves developing methods and tools to identify potentially harmful substances, defining acceptable concentration thresholds at different levels of biological organization, creating environmental quality indicators, and characterizing the causal links between toxicity and ecological impact. To tackle the issue of environmental protection, two research lines are being conducted simultaneously. Firstly, a priori risk assessment is being carried out to comprehend how contaminants affect individual life-history traits such as survival, growth, and reproduction. This information is then extrapolated to population and community levels. Secondly, a posteriori diagnosis is being conducted to evaluate the quality of natural environments and their effects on indigenous populations. Employing an interdisciplinary and integrated approach, along with the development of mathematical and statistical models for predictive purposes, the aim is to answer the key question of the change of scale. This refers to the link between the scale of observation of effects and that of the levels of biological organisation to be protected, such as the individual, population, community, and ecosystem. Methods and tools used to achieve this are: mechanistic effect modelling, dynamical systems, population dynamics models, Bayesian inference, and sensitivity analyses.

Domaines de recherche

Ecotoxicologie Ecosystèmes Environnement et Société Statistiques [math.ST] Modélisation et simulation

Compétences

Publications

"elisebilloir"

Survival data analyses in ecotoxicology: critical effect concentrations, methods and models. What should we use?

Carole Forfait-Dubuc , Sandrine Charles , Elise Billoir , Marie-Laure Delignette-Muller
Ecotoxicology, 2012, 21, pp.1072--1083. ⟨10.1007/s10646-012-0860-0⟩
Article dans une revue hal-02297003v1

Comparison of bioassays with different exposure time patterns: The added value of dynamic modelling in predictive ecotoxicology

Elise Billoir , Hélène Delhaye , Carole Forfait-Dubuc , Bernard Clément , Gaëlle Triffault-Bouchet
Ecotoxicology and Environmental Safety, 2012, 75, pp.80-86. ⟨10.1016/j.ecoenv.2011.08.006⟩
Article dans une revue halsde-00685679v1

What to do with NOECS/NOELS - prohibition or innovation?

Dr Fox , Elise Billoir , S. Charles , Marie-Laure Delignette-Muller , C. Lopes
Integr Environ Assess Manag, 2012, 8, pp.764--766. ⟨10.1002/ieam.1350⟩
Article dans une revue hal-02296816v1

Population-Level Modeling to Account for Multigenerational Effects of Uranium in Daphnia magna

P-A. Biron , S. Massarin , F. Alonzo , L. Garcia-Sanchez , Sandrine Charles
Environmental Science and Technology, 2012, 46, pp.1136--1143. ⟨10.1021/es202658b⟩
Article dans une revue hal-02297352v1

Bayesian modelling of daphnid responses to time-varying cadmium exposure in laboratory aquatic microcosms

Elise Billoir , Hélène Delhaye , Bernard Clément , Marie Laure Delignette-Muller , Sandrine Charles
Ecotoxicology and Environmental Safety, 2011, 74 (4), pp.693-702. ⟨10.1016/j.ecoenv.2010.10.023⟩
Article dans une revue halsde-00685607v1

A New Perspective on the Dunnett Procedure: Filling the Gap Between Noec/Loec and Ecx Concepts

Marie Laure Delignette-Muller , Carole Forfait-Dubuc , Elise Billoir , Sandrine Charles
Environmental Toxicology and Chemistry, 2011, 30, pp.2888-2891. ⟨10.1002/etc.686⟩
Article dans une revue hal-02299273v1

From individual to population level effects of toxicants in the tubicifid branchiura sowerbyi using threshold effect models in a bayesian framework

Virginie Ducrot , Elise Billoir , Alexandre R.R. Pery , Jeanne Garric , Sandrine Charles
Environmental Science and Technology, 2010, 44 (9), pp.3566-3571. ⟨10.1021/es903860w⟩
Article dans une revue ineris-00963240v1
Image document

DEBtox theory and matrix population models as helpful tools in understanding the interaction between toxic cyanobacteria and zooplankton

Elise Billoir , Aloysio da Silva Ferrão-Filho , Marie Laure Delignette-Muller , Sandrine Charles
Journal of Theoretical Biology, 2009, 258 (3), pp.380. ⟨10.1016/j.jtbi.2008.07.029⟩
Article dans une revue hal-00554502v1

A bayesian approach to analyse ecotoxicological data

Elise Billoir , Marie Laure Delignette-Muller , Alexandre R.R. Pery , Sandrine Charles
Environmental Science and Technology, 2008, 42 (23), pp.8978-8984. ⟨10.1021/es801418x⟩
Article dans une revue ineris-00963142v1

Statistical cautions when estimating DEBtox parameters

Elise Billoir , M.L. Delignette-Müller , A. Pery , Olivier Geffard , S. Charles
Journal of Theoretical Biology, 2008, 254 (1), pp.55-64. ⟨10.1016/j.jtbi.2008.05.006⟩
Article dans une revue hal-02591278v1

Integrating the lethal and sublethal effects of toxic compounds into the population dynamics of Daphnia magna: A combination of the DEBtox and matrix population models

Elise Billoir , A. Pery , S. Charles
Ecological Modelling, 2007, 203 (3-4), pp.204-214. ⟨10.1016/j.ecolmodel.2006.11.021⟩
Article dans une revue hal-02589932v1

Matrix population models as relevant modeling tools in ecotoxicology

S. Charles , Elise Billoir , C. Lopes , Arnaud Chaumot , James Devillers
Ecotoxicology Modeling, Emerging Topics in Ecotoxicology: Principles, Approaches and Perspectives 2, Springer Science, pp.261-298, 2009
Chapitre d'ouvrage hal-02592300v1