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Network topology of NaV1.7 mutations in sodium channel-related painful disorders

Sandrine Cestèle , Benedetta Terragni , Paolo Scalmani , Silvana Franceschetti , Massimo Mantegazza , et al.
BMC Systems Biology, 2017, 11 (1), pp.28. ⟨10.1186/s12918-016-0382-0⟩
Article dans une revue hal-03572479v1

First chemical synthesis of a scorpion α-toxin affecting sodium channels: The Aah I toxin of Androctonus australis hector

Sarrah M'Barek , Ziad Fajloun , Sandrine Cestèle , Christiane Devaux , Pascal Mansuelle , et al.
Journal of Peptide Science, 2004, 10 (11), pp.666-677. ⟨10.1002/psc.582⟩
Article dans une revue istex pasteur-02052144v1
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Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study

Patrick May , Simon Girard , Merle Harrer , Dheeraj Bobbili , Julian Schubert , et al.
The Lancet Neurology, 2018, 17 (8), pp.699-708. ⟨10.1016/S1474-4422(18)30215-1⟩
Article dans une revue hal-02352036v1

Depolarization Differentially Affects Allosteric Modulation by Neurotoxins of Scorpion α-Toxin Binding on Voltage-Gated Sodium Channels

Sandrine Cestèle , Dalia Gordon
Journal of Neurochemistry, 1998, 70 (3), pp.1217-1226. ⟨10.1046/j.1471-4159.1998.70031217.x⟩
Article dans une revue hal-02353194v1

Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus

Sandrine Cestèle , Gerardo Pavel Espino-Solis , Georgina Estrada , Timoteo Olamendi-Portugal , Elba Villegas , et al.
Toxicon, 2011, 57 (5), pp.739-746. ⟨10.1016/j.toxicon.2011.02.006⟩
Article dans une revue istex hal-02352079v1

Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine.

Sandrine Cestèle , Angelo Labate , Raffaella Rusconi , Patrizia Tarantino , Laura Mumoli , et al.
Epilepsia, 2013, 54 (5), pp.927-35. ⟨10.1111/epi.12123⟩
Article dans une revue hal-00854584v1

The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications

Andreas Brunklaus , Tobias Brünger , Tony Feng , Carmen Fons , Anni Lehikoinen , et al.
Brain - A Journal of Neurology , 2022, ⟨10.1093/brain/awac210⟩
Article dans une revue hal-03799139v1
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Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and NaV1.1 channels

Oana Chever , Sarah Zerimech , Paolo Scalmani , Louisiane Lemaire , Lara Pizzamiglio , et al.
The Journal of clinical investigation, 2021, 131 (21), pp.e142203. ⟨10.1172/JCI142203⟩
Article dans une revue hal-03411366v1
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Voltage-gated ion channels and gating modifier toxins.

William A. Catterall , Sandrine Cestèle , Vladimir Yarov-Yarovoy , Frank H. Yu , Keiichi Konoki , et al.
Toxicon, 2007, 49 (2), pp.124-41. ⟨10.1016/j.toxicon.2006.09.022⟩
Article dans une revue inserm-00378020v1
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A new scorpion venom toxin paralytic to insects that affects Na+ channel activation. Purification, structure, antigenicity and mode of action.

L. Borchani , P. Mansuelle , M. Stankiewicz , F. Grolleau , Sandrine Cestèle , et al.
European Journal of Biochemistry, 1996, 241 (2), pp.525-532. ⟨10.1111/j.1432-1033.1996.00525.x⟩
Article dans une revue pasteur-00878674v1

Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis

Sandrine Cestèle , Olfa Khalfallah , Marielle Jarjat , Laetitia Davidovic , Nicolas Nottet , et al.
STEM CELLS, 2017, 35 (2), pp.374-385. ⟨10.1002/stem.2505⟩
Article dans une revue hal-02352053v1
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Gain of function SCN1A disease‐causing variants: Expanding the phenotypic spectrum and functional studies guiding the choice of effective antiseizure medication

Sara Matricardi , Sandrine Cestèle , Marina Trivisano , Benedetta Kassabian , Nathalie Leroudier , et al.
Epilepsia, 2023, 64 (5), pp.1331-1347. ⟨10.1111/epi.17509⟩
Article dans une revue hal-04127124v1

BotIT6: a potent depressant insect toxin from Buthus occitanus tunetanus venom.

Thouraya Mejri , Lamia Borchani , Najet Srairi-Abid , Rym Benkhalifa , Sandrine Cestele , et al.
Toxicon, 2003, 41 (2), pp.163--171. ⟨10.1016/s0041-0101(02)00246-5⟩
Article dans une revue istex hal-01974936v1

Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: Properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum

Sandrine Cestèle , Giulia Bechi , Raffaella Rusconi , Sandrine Cestele , Pasquale Striano , et al.
Neurobiology of Disease, 2015, 75, pp.100-114. ⟨10.1016/j.nbd.2014.12.028⟩
Article dans une revue hal-02352057v1

Toxin III from Leiurus quinquestriatus quinquestriatus: A specific probe for receptor site 3 on insect sodium channels

Sandrine Cestèle
Insect Biochemistry and Molecular Biology, 1997, 27 (6), pp.523-528. ⟨10.1016/s0965-1748(97)00027-1⟩
Article dans une revue istex hal-02353201v1

Role of lysine and tryptophan residues in the biological activity of toxin VII (Ts gamma) from the scorpion Tityus serrulatus

Oussama Hassani , Pascal Mansuelle , Sandrine Cestèle , Madeleine Bourdeaux , Hervé Rochat , et al.
European Journal of Biochemistry, 1999, 260 (1), pp.76-86. ⟨10.1046/j.1432-1327.1999.00152.x⟩
Article dans une revue hal-02353145v1

Biochemical and Pharmacological Characterization of a Depressant Insect Toxin from the Venom of the Scorpion Buthacus arenicola

Sandrine Cestèle , Charles Kopeyan , Razika Oughideni , Pascal Mansuelle , Claude Granier , et al.
European Journal of Biochemistry, 1997, 243 (1-2), pp.93-99. ⟨10.1111/j.1432-1033.1997.93_1a.x⟩
Article dans une revue hal-02353211v1

α-Scorpion Toxins Binding on Rat Brain and Insect Sodium Channels Reveal Divergent Allosteric Modulations by Brevetoxin and Veratridine

Sandrine Cestèle , Rym Ben Khalifa , Marcel Pelhate , Hervé Rochat , Dalia Gordon
Journal of Biological Chemistry, 1995, 270 (25), pp.15153-15161. ⟨10.1074/jbc.270.25.15153⟩
Article dans une revue hal-02353226v1

Identification of Structural Elements of a Scorpion α-Neurotoxin Important for Receptor Site Recognition

Noam Zilberberg , Oren Froy , Erwann Loret , Sandrine Cestèle , Dorit Arad , et al.
Journal of Biological Chemistry, 1997, 272 (23), pp.14810-14816. ⟨10.1074/jbc.272.23.14810⟩
Article dans une revue hal-02353198v1
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Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine

Sandra Dhifallah , Eric Lancaster , Shana Merrill , Nathalie Leroudier , Massimo Mantegazza , et al.
Frontiers in Molecular Neuroscience, 2018, 11, pp.232. ⟨10.3389/fnmol.2018.00232⟩
Article dans une revue hal-02352023v1

The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications

Andreas Brunklaus , Tobias Brünger , Tony Feng , Carmen Fons , Anni Lehikoinen , et al.
Brain - A Journal of Neurology , 2022, ⟨10.1093/brain/awac210⟩
Article dans une revue hal-03753793v1
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Four disulfide-bridged scorpion beta neurotoxin CssII: heterologous expression and proper folding in vitro.

Georgina Estrada , Blanca I. Garcia , Emanuele Schiavon , Ernesto Ortiz , Sandrine Cestèle , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2007, 1770 (8), pp.1161-8. ⟨10.1016/j.bbagen.2007.04.006⟩
Article dans une revue inserm-00378025v1

Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects

Sandrine Cestèle , E. Schiavon , R. Rusconi , S. Franceschetti , M. Mantegazza
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (43), pp.17546-17551. ⟨10.1073/pnas.1309827110⟩
Article dans une revue hal-02352065v1

The impact of genetic and experimental studies on classification and therapy of the epilepsies

Sandrine Cestèle , Giuliano Avanzini , Massimo Mantegazza , Benedetta Terragni , Laura Canafoglia , et al.
Neuroscience Letters, 2018, 667, pp.17-26. ⟨10.1016/j.neulet.2017.05.026⟩
Article dans une revue hal-02562808v1

δ-Atracotoxins from Australian funnel-web spiders compete with scorpion α-toxin binding on both rat brain and insect sodium channels

Sandrine Cestèle , Yusheng Qu , John Rogers , Hervé Rochat , Todd Scheuer , et al.
FEBS Letters, 1998, 439 (3), pp.246-252. ⟨10.1016/s0014-5793(98)01378-7⟩
Article dans une revue hal-02353189v1

Scorpion α-like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage-gated sodium channels in mammals and insects

Sandrine Cestèle , Maria Stankiewicz , Pascal Mansuelle , Michel de Waard , Bénédicte Dargent , et al.
European Journal of Neuroscience, 1999, 11 (3), pp.975-985. ⟨10.1046/j.1460-9568.1999.00505.x⟩
Article dans une revue istex hal-02353142v1
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Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels.

Massimo Mantegazza , Sandrine Cestèle
The Journal of Physiology, 2005, 568 (Pt 1), pp.13-30. ⟨10.1113/jphysiol.2005.093484⟩
Article dans une revue inserm-00381745v1

Loss-of-function KCNH2 mutation in a family with long QT syndrome, epilepsy, and sudden death.

Sara Partemi , Sandrine Cestèle , Marianna Pezzella , Oscar Campuzano , Roberta Paravidino , et al.
Epilepsia, 2013, 54 (8), pp.e112-6. ⟨10.1111/epi.12259⟩
Article dans une revue hal-00854562v1

Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine

Sandrine Cestèle , Sandrine Cestele , Angelo Labate , Raffaella Rusconi , Patrizia Tarantino , et al.
Epilepsia, 2013, 54 (5), pp.927-935. ⟨10.1111/epi.12123⟩
Article dans une revue hal-02352076v1

Self-Limited Hyperexcitability: Functional Effect of a Familial Hemiplegic Migraine Mutation of the Nav1.1 (SCN1A) Na+ Channel

Sandrine Cestèle , P. Scalmani , R. Rusconi , B. Terragni , S. Franceschetti , et al.
Journal of Neuroscience, 2008, 28 (29), pp.7273-7283. ⟨10.1523/JNEUROSCI.4453-07.2008⟩
Article dans une revue hal-02352086v1