ASSOU SAID

Joffrey Mianné, Amel Nasri, Chloé Nguyen Van, Chloé Bourguignon, Mathieu Fieldès, et al.. CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles. BMC Biology, BioMed Central, 2022, 20 (1), pp.8. ⟨10.1186/s12915-021-01214-x⟩. ⟨hal-03518180⟩

Amel Nasri, Florent Foisset, Engi Ahmed, Zakaria Lahmar, Isabelle Vachier, et al.. Roles of Mesenchymal Cells in the Lung: From Lung Development to Chronic Obstructive Pulmonary Disease. Cells, MDPI, 2021, 10 (12), pp.3467. ⟨10.3390/cells10123467⟩. ⟨hal-03478861⟩

Nino Guy Cassuto, David Piquemal, Florence Boitrelle, Lionel Larue, Nathalie Lédée, et al.. Molecular Profiling of Spermatozoa Reveals Correlations between Morphology and Gene Expression: A Novel Biomarker Panel for Male Infertility. BioMed Research International , Hindawi Publishing Corporation, 2021, 2021, pp.1 - 14. ⟨10.1155/2021/1434546⟩. ⟨hal-03369698⟩

Mathieu Fieldes, Chloé Bourguignon, Said Assou, Amel Nasri, Aurélie Fort, et al.. Targeted therapy in eosinophilic chronic obstructive pulmonary disease. ERJ Open Research, European Respiratory Society, 2021, 7 (2), pp.00437-2020. ⟨10.1183/23120541.00437-2020⟩. ⟨hal-03200459⟩

Béryl Laplace-Builhé, Audrey Barthelaix, Said Assou, Candice Bohaud, Marine Pratlong, et al.. NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.6336. ⟨10.1038/s41467-021-26422-5⟩. ⟨hal-03646943⟩

Engi Ahmed, Mathieu Fieldes, Joffrey Mianné, Chloé Bourguignon, Amel Nasri, et al.. Generation of four severe early-onset chronic obstructive pulmonary disease (COPD) patient-derived induced pluripotent stem cell lines from peripheral blood mononuclear cells. Stem Cell Research, Elsevier, 2021, 56, pp.102550. ⟨10.1016/j.scr.2021.102550⟩. ⟨hal-03377712⟩

Yves-Marie Pers, Claire Bony, Isabelle Duroux-Richard, Laurène Bernard, Marie Maumus, et al.. miR-155 Contributes to the Immunoregulatory Function of Human Mesenchymal Stem Cells. Frontiers in Immunology, Frontiers, 2021, 12, pp.624024. ⟨10.3389/fimmu.2021.624024⟩. ⟨hal-03660057⟩

Gautier Tejedor, Béryl Laplace-Builhé, Patricia Luz-Crawford, Said Assou, Audrey Barthelaix, et al.. Whole embryo culture, transcriptomics and RNA interference identify TBX1 and FGF11 as novel regulators of limb development in the mouse. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.3597. ⟨10.1038/s41598-020-60217-w⟩. ⟨inserm-02498306⟩

Mathieu Fieldes, Engi Ahmed, Chloé Bourguignon, Joffrey Mianné, Martin Mélanie, et al.. Generation of the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor. Stem Cell Research, Elsevier, 2020, pp.102037. ⟨10.1016/j.scr.2020.102037⟩. ⟨hal-02965353⟩

Chloé Bourguignon, Charlotte Vernisse, Joffrey Mianné, Mathieu Fieldes, Engi Ahmed, et al.. Les organoïdes pulmonaires. médecine/sciences, EDP Sciences, 2020, 36 (4), pp.382-388. ⟨10.1051/medsci/2020056⟩. ⟨hal-02560622⟩

Joffrey Mianné, Chloé Bourguignon, Chloé Nguyen Van, Mathieu Fieldès, Amel Nasri, et al.. Pipeline for the Generation and Characterization of Transgenic Human Pluripotent Stem Cells Using the CRISPR/Cas9 Technology. Cells, MDPI, 2020, 9 (5), pp.1312. ⟨10.3390/cells9051312⟩. ⟨hal-03594394⟩

Said Assou, Nicolas Girault, Mathilde Plinet, Julien Bouckenheimer, Caroline Sansac, et al.. Recurrent Genetic Abnormalities in Human Pluripotent Stem Cells: Definition and Routine Detection in Culture Supernatant by Targeted Droplet Digital PCR. Stem Cell Reports, Elsevier, 2020, 14 (1), pp.1-8. ⟨10.1016/j.stemcr.2019.12.004⟩. ⟨hal-03396129⟩

M. Fieldès, E. Ahmed, C. Bourguignon, J. Mianné, C. Vernisse, et al.. Modélisation de l’épithélium bronchique dans la bronchopneumopathie chronique obstructive par les cellules souches pluripotentes induites humaines. Revue des Maladies Respiratoires, Elsevier Masson, 2020, 37 (3), pp.197-200. ⟨10.1016/j.rmr.2020.02.003⟩. ⟨hal-02507653⟩

Aurélien Linares, Said Assou, Marion Lapierre, Erwan Thouennon, Celine Duraffourd, et al.. Increased expression of the HDAC 9 gene is associated with antiestrogen‐resistance of breast cancers. Molecular Oncology, Elsevier, 2019, 13 (7), pp.1534-1547. ⟨10.1002/1878-0261.12505⟩. ⟨hal-02133612⟩

Engi Ahmed, Caroline Sansac, Said Assou, Delphine Gras, Aurélie Petit, et al.. Lung development, regeneration and plasticity: From disease physiopathology to drug design using induced pluripotent stem cells. Pharmacology and Therapeutics, Elsevier, 2018, 183, pp.58--77. ⟨10.1016/j.pharmthera.2017.10.002⟩. ⟨hal-01743899⟩

Said Assou, Julien Bouckenheimer, John de Vos. Concise Review: Assessing the Genome Integrity of Human Induced Pluripotent Stem Cells: What Quality Control Metrics?. STEM CELLS, AlphaMed Press, 2018, 36 (6), pp.814-821. ⟨10.1002/stem.2797⟩. ⟨hal-02340889⟩

Ismail Kaarouch, Nouzha Bouamoud, Aicha Madkour, Noureddine Louanjli, Saadani Brahim, et al.. Paternal age: Negative impact on sperm genome decays and IVF outcomes after 40 years. Molecular Reproduction and Development, Wiley, 2018, 85 (3), pp.271-280. ⟨10.1002/mrd.22963⟩. ⟨hal-03158098⟩

Hanae Lahlou, Emmanuel Nivet, Alejandra Lopez-Juarez, Arnaud Fontbonne, Said Assou, et al.. Enriched Differentiation of Human Otic Sensory Progenitor Cells Derived From Induced Pluripotent Stem Cells. Frontiers in Molecular Neuroscience, Frontiers Media, 2018, 11, pp.11:452. ⟨10.3389/fnmol.2018.00452⟩. ⟨hal-02395531⟩

Marie Christou‐kent, Zine‐eddine Kherraf, Amir Amiri‐yekta, Emilie Le Blévec, Thomas Karaouzène, et al.. PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice. EMBO Molecular Medicine, Wiley Open Access, 2018, 10 (5), pp.e8515. ⟨10.15252/emmm.201708515⟩. ⟨hal-01877992⟩

Alexandra Soler, Laure Cayrefourcq, Thibault Mazard, Anna Babayan, Pierre-Jean Lamy, et al.. Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes. Scientific Reports, Nature Publishing Group, 2018, 8, pp.15931. ⟨10.1038/s41598-018-34365-z⟩. ⟨hal-02292363⟩

Aicha Madkour, Nouzha Bouamoud, Ismail Kaarouch, Noureddine Louanjli, Saadani Brahim, et al.. Follicular fluid and supernatant from cultured cumulus-granulosa cells improve in vitro maturation in patients with polycystic ovarian syndrome. Fertility and Sterility, Elsevier, 2018, 110 (4), pp.710-719. ⟨10.1016/j.fertnstert.2018.04.038⟩. ⟨hal-03164781⟩

Julien Bouckenheimer, Patricia Fauque, Charles-Henri Lecellier, Céline Bruno, Thérèse Commes, et al.. Differential long non-coding RNA expression profiles in human oocytes and cumulus cells. Scientific Reports, Nature Publishing Group, 2018, 8 (1), ⟨10.1038/s41598-018-20727-0⟩. ⟨hal-01840077⟩

Engi Ahmed, Caroline Sansac, Mathieu Fieldes, Anne Bergougnoux, Chloé Bourguignon, et al.. Generation of the induced pluripotent stem cell line UHOMi001-A from a patient with mutations in CCDC40 gene causing Primary Ciliary Dyskinesia (PCD). Stem Cell Research, Elsevier, 2018, ⟨10.1016/j.scr.2018.09.019⟩. ⟨hal-01886353⟩

Joffrey Mianné, Engi Ahmed, Chloé Bourguignon, Mathieu Fieldes, Isabelle Vachier, et al.. Induced Pluripotent Stem Cells for Primary Ciliary Dyskinesia Modeling and Personalized Medicine. American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, 2018, 59 (6), pp.672-683. ⟨10.1165/rcmb.2018-0213TR⟩. ⟨hal-01878063⟩

John de Vos, Said Assou. Induced pluripotent stem cells: An unlimited source of organs for transplantation. Clinics and Research in Hepatology and Gastroenterology, Elsevier, 2017, 41 (3), pp.249 - 253. ⟨10.1016/j.clinre.2016.10.008⟩. ⟨hal-01794741⟩

Catherine Alix-Panabières, Laure Cayrefourcq, Thibault Mazard, Thierry Maudelonde, Eric Assenat, et al.. Molecular Portrait of Metastasis-Competent Circulating Tumor Cells in Colon Cancer Reveals the Crucial Role of Genes Regulating Energy Metabolism and DNA Repair. Clinical Chemistry, American Association for Clinical Chemistry, 2017, 63 (3), pp.700 - 713. ⟨10.1373/clinchem.2016.263582⟩. ⟨hal-01793403⟩

John de Vos, J. Bouckenheimer, C. Sansac, J.-M. Lemaître, Said Assou. Human induced pluripotent stem cells: A disruptive innovation. Current Research in Translational Medicine, Elsevier-Masson SAS, 2016, 64 (2), pp.91 - 96. ⟨10.1016/j.retram.2016.04.001⟩. ⟨hal-01840116⟩

Julien Bouckenheimer, Said Assou, Sébastien Riquier, Cyrielle Hou, Nicolas Philippe, et al.. Long non-coding RNAs in human early embryonic development and their potential in ART. Human Reproduction Update, Oxford University Press (OUP), 2016, 23 (1), pp.19 - 40. ⟨10.1093/humupd/dmw035⟩. ⟨hal-01819458⟩

Caroline Sansac, Said Assou, Julien Bouckenheimer, Jean-Marc Lemaitre, John de Vos. Les cellules souches pluripotentes induites : un nouveau paradigme pour l’étude des tissus humains. Biologie Aujourd'hui, EDP sciences, 2016, 210 (1), pp.1 - 8. ⟨10.1051/jbio/2016013⟩. ⟨hal-01840113⟩

Marion Lapierre, Aurélien Linares, Mathieu Dalvai, Céline Duraffourd, Sandrine Bonnet, et al.. Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors. Oncotarget, Impact journals, 2016, 7 (15), pp.19693-708. ⟨10.18632/oncotarget.7564⟩. ⟨hal-01873610⟩

Said Assou, Emilie Pourret, Marie Péquignot, Valérie Rigau, Vasiliki Kalatzis, et al.. Cultured Cells from the Human Oocyte Cumulus Niche Are Efficient Feeders to Propagate Pluripotent Stem Cells. Stem Cells and Development, Mary Ann Liebert, 2015, 24 (19), pp.2317-2327. ⟨10.1089/scd.2015.0043⟩. ⟨hal-01977969⟩

Delphine Haouzi, Laurence Bissonnette, Anna Gala, Said Assou, Frida Entezami, et al.. Endometrial Receptivity Profile in Patients with Premature Progesterone Elevation on the Day of hCG Administration. BioMed Research International , Hindawi Publishing Corporation, 2014, 2014, pp.951937. ⟨10.1155/2014/951937⟩. ⟨hal-03122694⟩

Said Assou, Ounissa Aït-Ahmed, Safia El Messaoudi, Alain Thierry, Samir Hamamah. Non-invasive pre-implantation genetic diagnosis of X-linked disorders. Medical Hypotheses, Elsevier, 2014, 83, pp.506--8. ⟨10.1016/j.mehy.2014.08.019⟩. ⟨hal-02181365⟩

Diego Sánchez-Martínez, Ewelina Krzywinska, Moeez Rathore, Anne Saumet, Amélie Cornillon, et al.. MicroRNAs: new candidates for the regulation of the human cumulus–oocyte complex. Human Reproduction, Oxford University Press (OUP), 2013, 28 (11), pp.3038-3049. ⟨10.1093/humrep/det321⟩. ⟨hal-02106446⟩

Said Assou, Imène Boumela, Delphine Haouzi, Cécile Monzo, Hervé Dechaud, et al.. Transcriptome Analysis during Human Trophectoderm Specification Suggests New Roles of Metabolic and Epigenetic Genes.. PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e39306. ⟨10.1371/journal.pone.0039306⟩. ⟨inserm-00726672⟩

S. Moussaddykine, Said Assou, Hervé Déchaud, Samir Hamamah. [Other actors in the oocyte and follicular growth: The role of microRNAs in the cumulus-oocyte dialog].. Gynécologie Obstétrique & Fertilité, Elsevier Masson, 2012, 40 (3), pp.170-3. ⟨10.1016/j.gyobfe.2011.10.011⟩. ⟨inserm-00664585⟩

Cécile Monzo, Delphine Haouzi, K. Roman, Said Assou, Hervé Dechaud, et al.. Slow freezing and vitrification differentially modify the gene expression profile of human metaphase II oocytes.. Human Reproduction, Oxford University Press (OUP), 2012, 27 (7), pp.2160-8. ⟨10.1093/humrep/des153⟩. ⟨inserm-00726705⟩

Ibtihel Smeti, Said Assou, Etienne Savary, Saber Masmoudi, Azel Zine. Transcriptomic analysis of the developing and adult mouse cochlear sensory epithelia. PLoS ONE, Public Library of Science, 2012, 7 (8), pp.e42987. ⟨10.1371/journal.pone.0042987⟩. ⟨inserm-00840290⟩

Zamalou Gisèle Ouandaogo, Nelly Frydman, Laetitia Hesters, Said Assou, Delphine Haouzi, et al.. Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo and in vitro oocyte maturation.. Human Reproduction, Oxford University Press (OUP), 2012, 27 (8), pp.2438-47. ⟨10.1093/humrep/des172⟩. ⟨inserm-00726681⟩

Qiang Bai, Said Assou, Delphine Haouzi, Jean-Marie Ramirez, Cécile Monzo, et al.. Dissecting the first transcriptional divergence during human embryonic development.. Stem Cell Reviews and Reports, Humana Press, 2012, 8 (1), pp.150-62. ⟨10.1007/s12015-011-9301-3⟩. ⟨inserm-00664573⟩

Imène Boumela, Said Assou, Abdel Aouacheria, Delphine Haouzi, Hervé Dechaud, et al.. Involvement of BCL2 family members in the regulation of human oocyte and early embryo survival and death: gene expression and beyond. Reproduction, BioScientifica, 2011, 141 (5), pp.549-561. ⟨ensl-00808957⟩

Said Assou, Imène Boumela, Delphine Haouzi, Tal Anahory, Hervé Dechaud, et al.. Dynamic changes in gene expression during human early embryo development: from fundamental aspects to clinical applications.. Human Reproduction Update, Oxford University Press (OUP), 2011, 17 (2), pp.272-90. ⟨10.1093/humupd/dmq036⟩. ⟨inserm-00512388⟩

Sylvie Tondeur, Céline Pangault, Tanguy Le Carrour, Yoann Lannay, Rima Benmahdi, et al.. Expression Map of the Human Exome in CD34+ Cells and Blood Cells: Increased Alternative Splicing in Cell Motility and Immune Response Genes.. PLoS ONE, Public Library of Science, 2010, 5 (2), pp.e8990. ⟨10.1371/journal.pone.0008990⟩. ⟨inserm-00453226⟩

Said Assou, Doris Cerecedo, Sylvie Tondeur, Véronique Pantesco, Outi Hovatta, et al.. A gene expression signature shared by human mature oocytes and embryonic stem cells.. BMC Genomics, BioMed Central, 2009, 10, pp.10. ⟨10.1186/1471-2164-10-10⟩. ⟨inserm-00369777⟩

Jean-Sébastien Annicotte, Emilie Blanchet, Carine Chavey, Irena Iankova, Safia Costes, et al.. The CDK4–pRB–E2F1 pathway controls insulin secretion. Nature Cell Biology, Nature Publishing Group, 2009, 11 (8), pp.1017-1023. ⟨10.1038/ncb1915⟩. ⟨hal-03066246⟩

Delphine Haouzi, Said Assou, K. Mahmoud, Sylvie Tondeur, Thierry Rème, et al.. Gene expression profile of human endometrial receptivity: comparison between natural and stimulated cycles for the same patients.. Human Reproduction, Oxford University Press (OUP), 2009, 24 (6), pp.1436-45. ⟨10.1093/humrep/dep039⟩. ⟨inserm-00377444⟩

Sophie Javerzat, Mélanie Franco, John Herbert, Natalia Platonova, Anne-Lise Peille, et al.. Correlating global gene regulation to angiogenesis in the developing chick extra-embryonic vascular system.. PLoS ONE, Public Library of Science, 2009, 4 (11), pp.e7856. ⟨10.1371/journal.pone.0007856⟩. ⟨inserm-00446190⟩

Jean-Sébastien Annicotte, Emilie Blanchet, Carine Chavey, Irena Iankova, Safia Costes, et al.. The CDK4-pRB-E2F1 pathway controls insulin secretion.. Nature Cell Biology, Nature Publishing Group, 2009, 11 (8), pp.1017-23. ⟨10.1038/ncb1915⟩. ⟨inserm-00418907⟩

Sylvie Tondeur, Said Assou, Laure Nadal, Samir Hamamah, John de Vos. [Biology and potential of human embryonic stem cells]. Annales de Biologie Clinique, John Libbey Eurotext, 2008, 66 (3), pp.241-7. ⟨10.1684/abc.2008.0224⟩. ⟨inserm-00358937⟩

Stéphan Gasca, Lionel Reyftmann, Franck Pellestor, Thierry Rème, Said Assou, et al.. Total fertilization failure and molecular abnormalities in metaphase II oocytes.. Reproductive BioMedicine Online, Elsevier, 2008, 17 (6), pp.772-81. ⟨10.1016/s1472-6483(10)60404-x⟩. ⟨inserm-00358936⟩

Said Assou, Tanguy Lecarrour, Sylvie Tondeur, Susanne Strom, Audrey Gabelle, et al.. A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas.. STEM CELLS, AlphaMed Press, 2007, 25 (4), pp.961-73. ⟨10.1634/stemcells.2006-0352⟩. ⟨inserm-00128925⟩

Stéphan Gasca, Franck Pellestor, Said Assou, Vanessa Loup, Tal Anahory, et al.. Identifying new human oocyte marker genes: a microarray approach.. Reproductive BioMedicine Online, Elsevier, 2007, 14 (2), pp.175-183. ⟨10.1016/s1472-6483(10)60785-7⟩. ⟨inserm-00131300⟩

Said Assou, Tal Anahory, Véronique Pantesco, Tanguy Le Carrour, Franck Pellestor, et al.. The human cumulus--oocyte complex gene-expression profile.. Human Reproduction, Oxford University Press (OUP), 2006, 21 (7), pp.1705-19. ⟨10.1093/humrep/del065⟩. ⟨inserm-00130809⟩

David Sarruf, Irena Iankova, Anna Abella, Said Assou, Stéphanie Miard, et al.. Cyclin D3 promotes adipogenesis through activation of peroxisome proliferator-activated receptor gamma.. Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (22), pp.9985-95. ⟨10.1128/MCB.25.22.9985-9995.2005⟩. ⟨inserm-00144667⟩