|
|
The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for (“squelching”) SRC-1 coactivator
Lucie Hyrsova
,
Tomas Smutny
,
Alejandro Carazo
,
Stefan Moravcik
,
Jana Mandikova
,
et al.
Article dans une revue
hal-01837977v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor
Nicolas Creusot
,
Matthieu Gassiot
,
Elina Alaterre
,
Barbara Chiavarina
,
Marina Grimaldi
,
et al.
Article dans une revue
hal-02899508v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way
Alice Marmugi
,
Céline Lukowicz
,
Frédéric Lasserre
,
Alexandra Montagner
,
Arnaud Polizzi
,
et al.
Article dans une revue
hal-01837194v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
On the mechanism of non-endosomial peptide-mediated cellular delivery of nucleic acids
Sébastien Deshayes
,
Sabine Gerbal-Chaloin
,
May Morris
,
Gudrun Aldrian-Herrada
,
Pierre Charnet
,
et al.
Article dans une revue
hal-03128831v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
MitoCeption: Transferring Isolated Human MSC Mitochondria to Glioblastoma Stem Cells
Brice Nzigou Mombo
,
Sabine Gerbal-Chaloin
,
Aleksandra Bokus
,
Martine Daujat-Chavanieu
,
Christian Jorgensen
,
et al.
Journal of visualized experiments : JoVE, 2017, 120, pp.e55245. ⟨10.3791/55245⟩
Article dans une revue
hal-01777706v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Human induced pluripotent stem cells in hepatology: beyond the proof of concept.
Sabine Gerbal-Chaloin
,
Natalie Funakoshi
,
Amandine Caillaud
,
Claire Gondeau
,
Benoite Champon
,
et al.
Article dans une revue
inserm-00921587v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Dissecting the first transcriptional divergence during human embryonic development.
Qiang Bai
,
Said Assou
,
Delphine Haouzi
,
Jean-Marie Ramirez
,
Cécile Monzo
,
et al.
Article dans une revue
inserm-00664573v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Mitochondrial Complex I activity signals antioxidant response through ERK5
Abrar Ul Haq Khan
,
Nerea Allende-Vega
,
Delphine Gitenay
,
Johan Garaude
,
Dang-Nghiem Vo
,
et al.
Article dans une revue
hal-01835615v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation
Abrar Ul Haq Khan
,
Hamideh Salehi
,
Catherine Alexia
,
Jose M Valdivielso
,
Milica Bozic
,
et al.
Article dans une revue
hal-03757316v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
Hugues de Boussac
,
Claire Gondeau
,
Philippe Briolotti
,
Cédric Duret
,
Fridolin Treindl
,
et al.
Article dans une revue
hal-01731561v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin Binding
Franck Da-Silva
,
Xavier Boulenc
,
Hélène Vermet
,
Pauline Compigne
,
Sabine Gerbal-Chaloin
,
et al.
Article dans une revue
hal-01837119v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
Rozenn Riou
,
Meriem Ladli
,
Sabine Gerbal-Chaloin
,
Pascale Bossard
,
Angélique Gougelet
,
et al.
eLife, 2020
Article dans une revue
hal-03024026v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes
Martin Krøyer Rasmussen
,
Patrick Balaguer
,
Bo Ekstrand
,
Martine Daujat-Chavanieu
,
Sabine Gerbal-Chaloin
Article dans une revue
hal-01837192v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
The WNT/ β -Catenin Pathway Is a Transcriptional Regulator of CYP2E1, CYP1A2, and Aryl Hydrocarbon Receptor Gene Expression in Primary Human Hepatocytes
Sabine Gerbal-Chaloin
,
Anne-Sophie Dumé
,
Philippe Briolotti
,
Sylvie Klieber
,
Edith Raulet
,
et al.
Article dans une revue
hal-03116200v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling
Philippe Briolotti
,
Laurent Chaloin
,
Patrick Balaguer
,
Franck da Silva
,
Veronika Tománková
,
et al.
Article dans une revue
hal-01838127v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Skeletal Muscle Interleukin-6 Regulates Hepatic Cytochrome P450 Expression: Effects of 16-Week High-Fat Diet and Exercise
Jakob Knudsen
,
Lærke Bertholdt
,
Anders Gudiksen
,
Sabine Gerbal-Chaloin
,
Martin Krøyer Rasmussen
Article dans une revue
hal-01837113v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Cedric Duret
,
Martine Daujat-Chavanieu
,
Jean-Marc Pascussi
,
Lydiane Pichard-Garcia
,
Patrick Balaguer
,
et al.
Article dans une revue
inserm-00086861v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Cold Preservation of Human Adult Hepatocytes for Liver Cell Therapy
Cédric Duret
,
Daniel Moreno
,
Anangi Balasiddaiah
,
Solene Roux
,
Phillipe Briolotti
,
et al.
Article dans une revue
hal-01838017v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds
Vanessa Delfosse
,
Beatrice Dendelé
,
Tiphaine Huet
,
Marina Grimaldi
,
Abdelhay Boulahtouf
,
et al.
Article dans une revue
hal-01838034v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring
Jean Nakhle
,
Khattar Khattar
,
Tülin Özkan
,
Adel Boughlita
,
Daouda Abba Moussa
,
et al.
Article dans une revue
hal-04156158v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
PBPK modeling of irbesartan: incorporation of hepatic uptake
Hélène Chapy
,
Sylvie Klieber
,
Priscilla Brun
,
Sabine Gerbal-Chaloin
,
Xavier Boulenc
,
et al.
Article dans une revue
istex
hal-01838123v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
Rozenn Riou
,
Meriem Ladli
,
Sabine Gerbal-Chaloin
,
Pascale Bossard
,
Angélique Gougelet
,
et al.
Article dans une revue
hal-03010546v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Sex dictates the constitutive expression of hepatic cytochrome P450 isoforms in Göttingen minipigs
Martin Krøyer Rasmussen
,
Carsten Scavenius
,
Sabine Gerbal-Chaloin
,
Jan Enghild
Article dans une revue
hal-02414371v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG
Martin Krøyer Rasmussen
,
Martine Daujat-Chavanieu
,
Sabine Gerbal-Chaloin
Article dans une revue
hal-01837154v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Design of a Novel Class of Peptide Inhibitors of Cyclin-dependent Kinase/Cyclin Activation
Claire Gondeau
,
Sabine Gerbal-Chaloin
,
Paul Bello
,
Gudrun Aldrian-Herrada
,
May Morris
,
et al.
Article dans une revue
hal-03117951v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway
Abrar Ul Haq Khan
,
Nerea Allende-Vega
,
Delphine Gitenay
,
Sabine Gerbal-Chaloin
,
Claire Gondeau
,
et al.
Article dans une revue
hal-01835605v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences.
Jean-Marc Pascussi
,
Sabine Gerbal-Chaloin
,
Cédric Duret
,
Martine Daujat-Chavanieu
,
Marie-José Vilarem
,
et al.
Article dans une revue
inserm-00162144v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response
Alison Iroz
,
Alexandra Montagner
,
Fadila Benhamed
,
Françoise Levavasseur
,
Arnaud Polizzi
,
et al.
Article dans une revue
hal-01837159v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|
|
|
Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes
Amar Abderrahmani
,
Loïc Yengo
,
Robert Caiazzo
,
Mickael Canouil
,
Stéphane Cauchi
,
et al.
Article dans une revue
hal-01837153v1
|
Partager
Gmail
Facebook
X
LinkedIn
More
|