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Romain Yvinec
112
Documents
Identifiants chercheurs
- ryvinec
- ResearcherId : AAB-4337-2021
- IdRef : 182662403
- 0000-0002-7020-3976
- Google Scholar : https://scholar.google.com/citations?user=gLqXl7oAAAAJ&hl=fr
Présentation
I am a permanent [INRAE](https://www.inrae.fr/) researcher since 2013 in the team [Biology of Signalling Systems](http://bios.tours.inra.fr/bios_group/) (BIOS) within the laboratory [Physiologie de la Reproduction et des Comportements](https://www6.val-de-loire.inrae.fr/physiologie_reproduction_comportements) (PRC). The BIOS team is an interdisciplinary team composed of biologists, informaticians and mathematicians. Our main research area is the study of the dynamics of cellular signalling networks induced by G protein coupled receptors (GPCR), using a system biology approach. We particularly focus on GPCR signaling systems involved in reproductive biology and social behavior.
I'm mathematician by training. My works deals with deterministic and stochastic models in biology, particulary from cellular and molecular biology (including signalling systems, reaction networks, gene expression, protein aggregation and structured population dynamics). I'm interested in hybrid modelling, and study stochastic processes, limit theorem, asymptotic properties. I'm also interested in parameter estimation for the dynamic model we study. The main applications I'm interested in concern reproductive biology.
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Mathematical modeling of adipocyte size distributions: identifiability and parameter estimation from rat data2024
Pré-publication, Document de travail
hal-04141173v3
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Modeling compartmentalization within intracellular signaling pathway2024
Pré-publication, Document de travail
hal-04098543v2
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A Lifschitz-Slyozov type model for adipocyte size dynamics : limit from Becker-Döring system and numerical simulation2023
Pré-publication, Document de travail
hal-04016144v1
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Some remarks about the well-posedness of lifshitz-slyozov's equations with nucleation kinetics2023
Pré-publication, Document de travail
hal-04099684v1
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Nonlinear compartmental modeling to monitor ovarian follicle population dynamics on the whole lifespan2022
Pré-publication, Document de travail
hal-03739205v1
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β-arrestins and endocrine-related GPCRsCellular Endocrinology in Health and Disease, Elsevier, pp.445-458, 2021, 978-0-12-819801-8. ⟨10.1016/B978-0-12-819801-8.00021-1⟩
Chapitre d'ouvrage
hal-03462802v1
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The follicle-stimulating hormone signaling network in gonadal cells.Alfredo Ulloa-Aguirre; Ya-Xiong Tao. Cellular endocrinology in health and disease, Second Edition, Academic Press, 486 p., 2021, 9780128198018. ⟨10.1016/B978-0-12-819801-8.00020-X⟩
Chapitre d'ouvrage
hal-03128409v1
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Workflow description to dynamically model beta-arrestin signaling networksBeta-arrestins- Methods and protocols, 1957, , 2019, Methods in Molecular Biology, ⟨10.1007/978-1-4939-9158-7_13⟩
Chapitre d'ouvrage
hal-02374486v1
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Follicle-stimulating hormone receptor: Advances and remaining challengesG protein-coupled receptors: emerging paradigms in activation, signaling and regulation- Part A, 338 (1ère ed.), Elsevier, pp.1-58, 2018, International Review of Cell and Molecular Biology, 978-0-12-813772-7. ⟨10.1016/bs.ircmb.2018.02.001⟩
Chapitre d'ouvrage
hal-02373607v1
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Deterministic and stochastic Becker-Döring equations: Past and recent mathematical developmentsStochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology, Editions Springer, pp.175-204, 2016, ⟨10.1007/978-3-319-62627-7⟩
Chapitre d'ouvrage
hal-01512134v2
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Some contributions to the study of population dynamics models and coagulation-fragmentationProbability [math.PR]. Université de Tours, 2020
HDR
tel-03138658v1
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Probabilistic modeling in cellular and molecular biologyGeneral Mathematics [math.GM]. Université Claude Bernard - Lyon I, 2012. English. ⟨NNT : 2012LYO10154⟩
Thèse
tel-00749633v2
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Time scale separation in life-long ovarian follicles population dynamics modelSéminar EDP/ProbaStat Laboratoire de Mathématiques et Applications (LMA) de Poitiers, Mar 2023, Poitiers, France
Communication dans un congrès
hal-04194051v1
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Comparative dynamics of female germ cell populations : insight from imaging and multiscale modelingJournées INRAE-INRIA 2023, Jul 2023, Nancy, France
Communication dans un congrès
hal-04194047v1
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Time scale separation in life-long ovarian follicles population dynamics modelSeminar Mathematical Biology at Duke University, Oct 2022, online, United States
Communication dans un congrès
hal-04194053v1
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Stochastic Becker-Döring model: large population and large time results for phase transition phenomenaChemical Reaction Networks Workshop, Jul 2022, Turin, Italy
Communication dans un congrès
hal-03727240v1
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Stochastic Becker-Döring model: large population and large time results for phase transition phenomenaSeminar "Seminario de Ecuaciones Diferenciales", University of Granada, Dec 2022, Granada, Spain
Communication dans un congrès
hal-04194058v1
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Time scale separation in life-long ovarian follicles population dynamics modelECMTB 2022 - The 12th European Conference on Mathematical and Theoretical Biology, Sep 2022, Heidelberg, Germany
Communication dans un congrès
hal-04194057v1
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Kinetic biased signaling: towards a system biology definition of drugs selectivity.Gonadotropins in the Physiopathology: Current advances in the Mechanisms of Action, Le studium, Sep 2022, Online, France
Communication dans un congrès
hal-04194064v1
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Stochastic Becker-Döring model: large population and large time results for phase transition phenomenaSeminar on the Mathematics of Reaction Networks, Nov 2022, online, Italy
Communication dans un congrès
hal-04194061v1
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Modeling (some aspects of ) the female reproductive systemSéminaire d’analyse appliquée A³, Laboratoire Amiénois de Mathématique Fondamentale et Appliquée, Oct 2021, Amiens, France
Communication dans un congrès
hal-03727263v1
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Dynamical modeling of reaction networks. Application to biased signalingMapping Group Online Symposium, Dec 2021, Online, France
Communication dans un congrès
hal-03727416v1
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Ovarian follicle morphogenesisCompuCell3D Multicell Virtual-Tissue Modeling Summer School, Aug 2020, Online, United States
Communication dans un congrès
hal-03115079v1
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Dynamical modeling of reaction networks and biased signaling. Mathematics of system biology8th Workshop of the GDR35 - Bioinformatics and biomathematical approaches to integrate the GPCR signals, Nov 2020, online, France
Communication dans un congrès
hal-03727411v1
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Modeling GPCR-induced biased signaling Towards a system biology definition of drugs selectivity9th GDR3545-GPCR international meeting, Nov 2020, Online, France. pp.1-42
Communication dans un congrès
hal-03115093v1
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Dynamical modeling of reaction networksMathematics of system biology2020 Workshop - ‘bioinformatics and biomathematical approaches to integrate the GPCR signal, Nov 2020, Online, France. pp.1-70
Communication dans un congrès
hal-03115099v1
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Modeling (some aspects of ) the female reproductive systemThematic Month on Mathematical Issues in Biology - Mathematics of complex systems in biology and medicine, Feb 2020, Luminy, France. pp.1-65
Communication dans un congrès
hal-03115069v1
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Kinetic biased signaling: towards a system biology definition of drugs selectivityThematic Month on Mathematical Issues in Biology - Networks and molecular biology, Mar 2020, Luminy, France. pp.1-75
Communication dans un congrès
hal-03115087v1
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Stochastic model of nucleation Becker-Döring Model1ere réunion du GDR MéDynA, Oct 2019, Sainte-Montaine, France
Communication dans un congrès
hal-03115114v1
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Stochastic population dynamics applied to ovarian follicles developmentBioHasard 2019, Aug 2019, Rennes, France
Communication dans un congrès
hal-03115063v1
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Modélisation mathématique de processus d’assemblage (protéı̈ques)1ere réunion du GDR MéDynA, Oct 2019, Sainte-Montaine, France. pp.1-35
Communication dans un congrès
hal-03115106v1
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Dynamique de populations cellulaires structures : morphogenèse des follicules ovariensATMOSPHASE, Mar 2019, Paris, France
Communication dans un congrès
hal-03115057v1
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Stochastic single gene expression model: analytical results on bursting modelsReverse mathematical methods for reconstructing molecular dynamics in single cell, Oct 2018, Pise, Italy. pp.1-45
Communication dans un congrès
hal-03115052v1
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Using dynamical reaction network to infer drugs selectivity in pharmacologyICSB 2018, Oct 2018, Lyon, France. pp.1-66
Communication dans un congrès
hal-03115045v1
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Modeling (some aspects of) the female reproductive system : Gonadotropin and follicular dynamicsCEMRACS 2018, Jul 2018, Luminy, France
Communication dans un congrès
hal-03115049v1
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Dynamiques de populations cellulaires structurées Morphogenèse des follicules ovariensSession du GDR Mamovi 2017, 2017, Villeurbanne, France
Communication dans un congrès
hal-02785500v1
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Biased signaling and L1 penalizationODE Modelling in Systems Biology, Sep 2017, freibourg, Germany
Communication dans un congrès
hal-02785169v1
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Building GPCR signalisation networks. Example of the FSH receptor6.Annual Meeting of the CNRS GDR-3545 G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med), Nov 2017, Paris, France
Communication dans un congrès
hal-02794534v1
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Time scales in a coagulation-fragmentation model, Nucleation Time in Stochastic Becker-Döring ModelWorkshop on Protein Aggregation: Biophysics and Mathematics, Jun 2017, vienna, Austria
Communication dans un congrès
hal-02785742v1
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Les maths de la biologie des systèmesSeminar at the Groupe de travail Bio-Maths Tours/Orléans, 2016, Tours, France
Communication dans un congrès
hal-02794535v1
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Nucleation time in stochastic Becker-Doring model11. AIMS Conference on Dynamical Systems, Differential Equations and Applications, American Institute of Mathematical Science (AIMS). USA., Jul 2016, Orlando, United States. 45 diapositives
Communication dans un congrès
hal-02797058v1
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Probalistic and piecewise deterministic models in biologyJournées MAS 2016. Phénomènes complexes et hétérogènes, Société de Mathématiques Appliquées et Industrielles (SMAI). FRA., Aug 2016, Grenoble, France. pp.1-19
Communication dans un congrès
hal-01595098v1
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Time scales in a coagulation-fragmentation model2. BCAM Workshop on Nonlinear Dynamics in Biological Systems, Basque Center for Applied Mathematics (BCAM). ESP., Sep 2016, Bilbao, Spain
Communication dans un congrès
hal-02792839v1
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Stochastic coagulation-fragmentation models for the study of protein aggregation phenomenaStochastic Dynamical Systems in Biology: Numerical Methods and Applications, Isaac Newton Institute. GBR., Jan 2016, Cambridge, United Kingdom. 31 diapositives
Communication dans un congrès
hal-02795563v1
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From Becker-Doring to Lifshitz-Slyozov: deriving the boundary conditionBIOMAT 2015, Instituto Nacional de Matemática Pura e Aplicada. BRA., Mar 2015, Cabo Frio, Brazil
Communication dans un congrès
hal-02792548v1
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Bursting in gene expression modelColloque PDMP, Agence Nationale de la Recherche (ANR). FRA., May 2015, Saint Martin de Londres, France
Communication dans un congrès
hal-02797859v1
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Accurate parameter optimization leads to predictive dynamical models for systems biologyDesign, Optimization and Control in Systems and Synthetic Biology DOC'15, Ecole Normale Supérieure - Paris (ENS Paris). FRA., Nov 2015, Paris, France
Communication dans un congrès
hal-02799275v1
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Accute parameter optimization leads to predictive dynamical models for systems biologyPerspectives in Environmental and Systems Biology, Structure Fédérative de Recherche (SFR). FRA., Apr 2015, Grenoble, France
Communication dans un congrès
hal-02799266v1
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Nucleation time in coagulation-fragmentation modelsJournées Modélisation Aléatoire et Statistique de la SMAI (Société de Mathématiques Appliquées et Industrielles), Société de Mathématiques Appliquées et Industrielles (SMAI). FRA., Jun 2015, Les Karellis, France
Communication dans un congrès
hal-02794818v1
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Stochastic single gene expression model: analytical results on bursting and rate production estimationICB Seminar, Oct 2015, Munich, France
Communication dans un congrès
hal-03115037v1
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Passage du discret au continu pour un modèle d'agrégation fragmentationSéminaire de Probabilités et Théorie Ergodique, ( LMPT ), Oct 2015, Tours, France
Communication dans un congrès
hal-03115039v1
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Bursting in gene expressionColloque PDMP, Agence Nationale de la Recherche (ANR). FRA., Nov 2015, Tours, France
Communication dans un congrès
hal-02797860v1
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Accurate parameter optimization leads to predictive dynamical models for systems biology23. Journée du projet CASCIMODOT, Université d'Orléans (UO). FRA. Université François Rabelais (Tours)., Dec 2015, Tours, France
Communication dans un congrès
hal-02793656v1
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From Becker-Döring to Lifshitz-Slyozov: deriving the non-local boundary condition of a non-linear transport equationWorkshop on Multiscale and Hybrid Modelling in Cell and Cell Population Biology, Université Pierre et Marie Curie - Paris 6 (UPMC). Paris, FRA., Mar 2015, Paris, France. ⟨10.1051/itmconf/20150500017⟩
Communication dans un congrès
hal-02741964v1
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Towards nonlinear cell population model structured by molecular content9. European Conference on Mathematical and Theoretical Biology - ECMTB14, Chalmers University of Technology. SWE., Jun 2014, Göteborg, Sweden
Communication dans un congrès
hal-02797850v1
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Towards nonlinear cell population model structured by molecular contentStructured Integro-Differential models in Mathematical Biology, Vienna International Science Conferences and Events Association. AUT., Apr 2014, Vienne, Austria
Communication dans un congrès
hal-02797854v1
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Temps de premier passage pour le modèle de nucléation aléatoire de Becker-DoringSéminaire du Laboratoire de Mathématiques Appliquées de Compiègne, Feb 2013, Compiègne, France
Communication dans un congrès
hal-03115032v1
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Modèle probabiliste multi-échelle de différentiation cellulaireGroupe de Travail Maths bio et santé, Laboratoire Jacques-Louis Lions, Feb 2013, Paris, France
Communication dans un congrès
hal-03115016v1
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Modeles probabiliste de nucléationÉcole d'été Modélisation en dynamique des populations et évolution, Probabilité et EDP, Sep 2012, La Londe-Les Maures, France
Communication dans un congrès
hal-03115008v1
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Modeles stochastiques d'expression des genesJournées de probabilités 2012, Jun 2012, Roscoff, France
Communication dans un congrès
hal-03115003v1
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Modeles probabiliste de nucléation-polymérisationJournées Modélisation Mathématiques et Calcul Scientifique, Sep 2012, Villeurbanne, France
Communication dans un congrès
hal-03115006v1
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Stochastic self-regulated gene expression model5th International Conference on Stochastic Analysis and its Applications (ICSAA 2011), Sep 2011, Bonn, Germany
Communication dans un congrès
hal-03114998v1
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Modeles stochastiques d'expression des genesSéminaire des thésards du Centre de Mathématiques Appilquées de Polytechnique (CMAP), Dec 2011, Paris, France
Communication dans un congrès
hal-03115001v1
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Intrinsic and Extrinsic Noise Effects on Molecular Distributions in BacteriaSMB Annual Conference,, Jul 2010, Rio de Janerio, Brazil
Communication dans un congrès
hal-03133868v1
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Intrinsic and Extrinsic Noise Effects on Molecular Distributions in Bacteria11th International Conference on Systems Biology, (ICSB 2010), Oct 2010, Edinburgh, United Kingdom
Communication dans un congrès
hal-03133870v1
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Intrinsic and Extrinsic Noise Effects on Molecular Distributions in BacteriaFirst International workshop on Differential and Integral Equations with Applications in Biology and Medicine (DIEBM 2010), Sep 2010, Mytilène, Samos island, Greece
Communication dans un congrès
hal-03114866v1
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Stochastic Nucleation-Polymerization Model of Prion fibrils formationCAMBAM Seminar Serie, Apr 2010, Montreal, Canada
Communication dans un congrès
hal-03114819v1
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Stochastic Model of Prion's Disease: Nucleation-Polymerisation Model Part IIMathematical Biology Seminar Series at the Center for Mathematical Biology, University of Alberta, Mar 2010, Edmonton, Canada
Communication dans un congrès
hal-03114822v1
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Modeling Ovarian Folliculogenesis: Morphogenesis and Population DynamicsREPROSCIENCES 2019, Apr 2019, Toulouse, France
Poster de conférence
hal-03115058v1
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KINETIC BIASED SIGNALING : A SYSTEM BIOLOGY DEFINITION OF DRUGS SELECTIVITY8ème conférence internationale GDR3545-GPCR, Oct 2019, Montpellier, France
Poster de conférence
hal-03115082v1
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The translatome of the FSH receptor reveals tha several FSH-responsive signaling effectors are co-translated in primary rat Sertoli cells2. Journées du GdR 3606 Repro, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro
Poster de conférence
hal-01603078v1
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Multiscale modeling of the morphogenesis of ovarian follicles: a cell-dynamics based approach2. Journées du GdR 3606 Repro, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro
Poster de conférence
hal-01606594v1
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Intégration des contraintes spatiales dans la modélisation dynamique d’un système biologique complexe : le réseau de signalisation FSHJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase 2016), Apr 2016, Tours, France. , 115 p., 2016, Crédits Incitatifs financés entre 2011 et 2014
Poster de conférence
hal-02742541v1
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Beta-arrestin 2 barcode of phosphorylation: impact on beta-arrestin-dependent signaling3. Annual Meeting of the GDR 3545 RCPG-PhysioMed, Oct 2014, Montpellier, France. 2014
Poster de conférence
hal-02793437v1
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Parameter estimation in signaling systemsInternational Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors
Poster de conférence
hal-02740420v1
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Bursting and division in a nonlinear cell population modelPoster de conférence hal-02796022v1 |
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Dynamics of the prion proliferationPRION 2011, May 2011, Montreal, Canada
Poster de conférence
hal-03114887v1
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Getting to understand more and more a (simple?) model of stochastic gene expression7th International Congress on Industrial and Applied Mathematics (ICIAM 2011), Jul 2011, Vancouver, Canada
Poster de conférence
hal-03114889v1
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Dynamics of the prion proliferation6th Annual McGill Biophysical Chemistry Symposium, McGill University, 2010, Montreal, Canada
Poster de conférence
hal-03115013v1
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Comprendre la signalisation cellulaire à l'aide de modèles mathématiquesMaster. France. 2020
Cours
hal-03727337v1
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Vocabulaire et formalisme de modélisation de systèmes dynamiques en biologieDoctorat. France. 2019
Cours
hal-03727380v1
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Chemical Reaction Network Theory, notations and selected results2016
Cours
hal-02794650v1
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Piecewise deterministic Markov processes, applications in biology3rd cycle. Mini-cours chercheur (Laboratoire Jacques Louis-Lions, Université Paris VI), 2015, 24 p
Cours
hal-02795547v1
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Boundary value for a nonlinear transport equation emerging from a stochastic coagulation-fragmentation type model2015
Autre publication scientifique
hal-02801324v1
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From a stochastic Becker-Döring model to the Lifschitz-Slyozov equation with boundary value2014
Autre publication scientifique
hal-01123221v1
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Adiabatic reduction of models of stochastic gene expression with bursting2013
Autre publication scientifique
hal-02806255v1
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On the bursting of gene products2011
Autre publication scientifique
hal-00651588v1
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Probabilistic and Piecewise Deterministic models in BiologyESAIM: Proceedings and Surveys, 60, pp.225-245, 2017, ⟨10.1051/proc/201760225⟩
Proceedings/Recueil des communications
hal-01549687v1
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