Spiroimine toxins in complex with nicotinic acetylcholine receptors: structure and dynamics
Romulo Araoz
,
Laurent Chabaud
,
Catherine Guillou
,
Jordi Molgó
,
Bogdan Iorga
Article dans une revue
hal-00647637v1
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Synthetic Pinnatoxins A and G Reversibly Block Mouse Skeletal Neuromuscular Transmission In Vivo and In Vitro
Evelyne Benoit
,
Aurélie Couesnon
,
Jiri Lindovsky
,
Bogdan Iorga
,
Rómulo Aráoz
,
et al.
Article dans une revue
hal-02194723v1
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The cyclic imine Prorocentrolide-A obtained from cultured Japanese Prorocentrum lima dinoflagellates target muscle- and neuronal-type nicotinic acetylcholine receptors
Muriel Amar
,
Rómulo Aráoz
,
Bogdan Iorga
,
Takeshi Yasumoto
,
Denis Servent
,
et al.
Article dans une revue
hal-03164771v1
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The neurotoxic effect of 13, 19-didesmethyl and 13-desmethyl spirolide C phycotoxins is mainly mediated by nicotinic rather than muscarinic acetylcholine receptors.
Rómulo Aráoz
,
Gilles Ouanounou
,
Bogdan I Iorga
,
Amélie Goudet
,
Doria Alili
,
et al.
Article dans une revue
hal-01165573v1
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Solid-phase receptor-based assay for the detection of cyclic imines by chemiluminescence, fluorescence, or colorimetry.
Laura P Rodríguez
,
Natalia Vilariño
,
Jordi Molgó
,
Rómulo Aráoz
,
Alvaro Antelo
,
et al.
Article dans une revue
hal-00637241v1
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Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives
Rómulo Aráoz
,
Philipp Hess
,
Franck Pélissier
,
Evelyne Benoit
,
Denis Servent
,
et al.
5th nAChR satellite symposium on « Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science » , Oct 2015, Chicago, United States. pp.622,
⟨10.1016/j.bcp.2015.08.007⟩
Communication dans un congrès
hal-02334385v1
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Development of a Solid-Phase Receptor-Based Assay for the Detection of Cyclic Imines Using a Microsphere-Flow Cytometry System.
Laura Pérez Rodríguez
,
Natalia Vilariño
,
Jordi Molgó
,
Rómulo Aráoz
,
M. Carmen Louzao
,
et al.
Article dans une revue
hal-00781176v1
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Les spirolides: une famille de toxines émergentes qui contaminent les mollusques bivalves
Riadh Marrouchi
,
Sébastien Schlumberger
,
Evelyne Benoit
,
Rómulo Aráoz
,
Riadh Kharrat
,
et al.
Benoit E., Goudey-Perrière F., Marchot P. & Servent D. Toxines et fonctions cholinergiques neuronales et non neuronales , Editions de la SFET, Châtenay-Malabry, France, pp.13-17, 2008, Collection Rencontres en toxinologie
Chapitre d'ouvrage
hal-00348267v1
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6,6-Spiroimine analogs of (-)-gymnodimine A: synthesis and biological evaluation on nicotinic acetylcholine receptors.
Leslie Duroure
,
Thierry Jousseaume
,
Rómulo Aráoz
,
Elvina Barré
,
Pascal Retailleau
,
et al.
Article dans une revue
hal-00637236v1
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Detection of 13, 19-didesmethyl C spirolide by fluorescence polarization using Torpedo electrocyte membranes.
Eva S Fonfría
,
Natalia Vilariño
,
Jordi Molgó
,
Rómulo Aráoz
,
Paz Otero
,
et al.
Article dans une revue
istex
hal-00474310v1
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Metabolism of the lipophilic phycotoxin 13-Desmethylspirolide C using human and rat in vitro liver models
Jimmy H Alarcan
,
Estelle Dubreil-Cheneau
,
Antoine H Huguet
,
Romulo Araoz
,
Françoise Brée
,
et al.
Article dans une revue
anses-02083152v1
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Diversity in the binding interactions of nicotinic ligands to the nAChRs and associated conformational fluctuations − Insights into the core motif dictating antagonism
Yves Bourne
,
Gerlind Sulzenbacher
,
Zoran Radić
,
Laurent Chabaud
,
Rómulo Aráoz
,
et al.
RT26 – 26th Meeting of the French Society of Toxinology – Bioengineering of Toxins , French Society of Toxinology (SFET), Dec 2019, Paris, France
Communication dans un congrès
hal-04469851v1
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Cyclic imine toxins: chemistry, origin, metabolism, pharmacology, toxicology, and detection
Jordi Molgó
,
Romulo Aráoz
,
Evelyne Benoit
,
Bogdan I Iorga
Botana, L.M.
Seafood and freshwater toxins. Pharmacology physiology and detection. 3rd , Taylor & Francis, pp.951-990, 2014, 978-1-4665-0514-8.
⟨10.1201/b16662-39⟩
Chapitre d'ouvrage
hal-00955771v1
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The cyclic imine family of dinoflagellate toxins targeting nicotinic acetylcholine receptors
Jordi Molgó
,
Muriel Amar
,
Rómulo Aráoz
,
Evelyne Benoit
,
Bogdan Iorga
,
et al.
Proceedings/Recueil des communications
hal-02334357v1
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Towards an immunodiagnostic test for leprosy.
Romulo Aráoz
,
Nadine Honoré
,
Sayera Banu
,
Caroline Demangel
,
Yakouba Cissoko
,
et al.
Article dans une revue
pasteur-01370874v1
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The block of skeletal muscle nicotinic acetylcholine receptors caused by cyclic imine toxins can be antagonized by 3,4-diaminopyridine at isolated mouse neuromuscular preparation
Nicolas Lamassiaude
,
Evelyne Benoit
,
Rómulo Aráoz
,
Armen Zakarian
,
Denis Servent
,
et al.
PHYCOTOX 2023 - GDR Annual Conference on Toxic Microalgae , Institut Francais de Recherche pour l’Exploitation de la Mer (Ifremer), May 2023, Nantes, France
Communication dans un congrès
hal-04473953v1
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Physical and virtual screening methods for marine toxins and drug discovery targeting nicotinic acetylcholine receptors.
Jordi Molgó
,
Rómulo Aráoz
,
Evelyne Benoit
,
Bogdan I Iorga
Article dans une revue
hal-00856775v1
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Colorimetric microtiter plate receptor-binding assay for the detection of freshwater and marine neurotoxins targeting the nicotinic acetylcholine receptors.
Fernando Rubio
,
Lisa Kamp
,
Justin Carpino
,
Erin Faltin
,
Keith Loftin
,
et al.
Article dans une revue
hal-01165541v1
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Detection of gymnodimine-A and 13-desmethyl C spirolide phycotoxins by fluorescence polarization.
Natalia Vilariño
,
Eva S Fonfría
,
Jordi Molgó
,
Rómulo Aráoz
,
Luis M Botana
Article dans une revue
hal-00378092v1
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Total synthesis of pinnatoxins A and G and revision of the mode of action of pinnatoxin A.
Romulo Araoz
,
Denis Servent
,
Jordi Molgó
,
Bogdan I Iorga
,
Carole Fruchart-Gaillard
,
et al.
Article dans une revue
hal-00634136v1
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Micro-transplantation de membranes natives dans l'ovocyte de Xénope pour la reconstitution des récepteurs nicotiniques à l'acétylcholine in vitro et l'étude d'agents neurotoxiques.
Rómulo Aráoz
,
Muriel Amar
,
Sandrine Lecardeur
,
Roland Bournaud
,
Philippe Fossier
,
et al.
Journée scientifique NRBC mars 2006 , 2006, Grenoble, France
Communication dans un congrès
hal-00125071v1
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NeuroTorp, a lateral flow test based on toxin-receptor affinity for in-situ early detection of cyclic imine toxins
Fanny Noirmain
,
Julie Dano
,
Nathalie Hue
,
Jesús Gonzalez-Jartin
,
Luis Botana
,
et al.
Article dans une revue
hal-03876882v1
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Diversity in the binding interactions of marine phycotoxins to AChBP, the soluble nAChR surrogate
P. Marchot
,
Gerlind Sulzenbacher
,
Zoran Radic
,
Rómulo Aráoz
,
Emmanuelle Reynaud
,
et al.
XVth International Symposium on Cholinergic Mechanisms , Oct 2017, Marseille, France. pp.196,
⟨10.1111/jnc.13925⟩
Communication dans un congrès
hal-02334376v1
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Spirolides and Cyclic Imines: Toxicological Profile
Jordi Molgó
,
Evelyne Benoit
,
Rómulo Aráoz
,
Armen Zakarian
,
Bogdan Iorga
Chapitre d'ouvrage
hal-02334618v1
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Pinnatoxins: an emergent family of marine phycotoxins targeting nicotinic acetylcholine receptors with high affinity
Rómulo Aráoz
,
Denis Servent
,
Jordi Molgo
,
Bogdan Iorga
,
C. Fruchard-Gaillard
,
et al.
J. Barbier, E. Benoit, N. Gilles, D. Ladant, M.-F. Martin-Eauclaire, C. Mattéi, J. Molgó, M.R. Poppof & D. Servent.
Toxins and Ion transfers ,
SFET Publications , pp.43-47, 2011, Collection Rencontres en Toxinologie, 1760-6004
Chapitre d'ouvrage
hal-02334617v1
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Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α12βγδ nAChRs.
Yves Bourne
,
Gerlind Sulzenbacher
,
Zoran Radić
,
Rómulo Aráoz
,
Morgane Reynaud
,
et al.
Article dans une revue
hal-01178822v1
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Parazoanthoxanthin A blocks Torpedo nicotinic acetylcholine receptors.
Klara Bulc Rozman
,
Rómulo Aráoz
,
Kristina Sepčić
,
Jordi Molgó
,
Dušan Suput
Article dans une revue
istex
hal-00464523v1
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A monitoring study of repetitive surgical oocyte harvest in Xenopus laevis
Patricia Villeneuve
,
G. Esnault
,
Evelyne Benoit
,
Jordi Molgó
,
Rómulo Aráoz
Toxins and Ion transfers , SFET Publications, pp.173-178, 2011, Collection Rencontres en Toxinologie
Chapitre d'ouvrage
hal-00738606v1
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Bioassays for detection and identification of cyclic imine toxins
Rómulo Aráoz
,
Jordi Molgó
,
Denis Servent
Harmful Algae 2018 – From Ecosystems to Socio-Ecosystems , Philipp Hess, Oct 2018, Nantes, France. pp.118-121
Communication dans un congrès
hal-03091407v1
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Antigen discovery: a postgenomic approach to leprosy diagnosis.
Romulo Aráoz
,
Nadine Honoré
,
Sungae Cho
,
Jong-Pill Kim
,
Sang-Nae Cho
,
et al.
Article dans une revue
pasteur-00204119v1
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