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Revisiting the Timing of Action of the PAG Adaptor Using Quantitative Proteomics Analysis of Primary T Cells

K. Reginald , K. Chaoui , R. Roncagalli , M. Beau , M. Goncalves Menoita , et al.
Journal of Immunology, 2015, 195 (11), pp.5472-5481. ⟨10.4049/jimmunol.1501300⟩
Article dans une revue hal-03080169v1

ARHGAP45 controls naïve T‐ and B‐cell entry into lymph nodes and T‐cell progenitor thymus seeding

Le He , Marie‐pierre Valignat , Lichen Zhang , Lena Gelard , Fanghui Zhang , et al.
EMBO Reports, 2021, 22 (4), ⟨10.15252/embr.202052196⟩
Article dans une revue hal-03375204v1

Interactomics and structure-function analysis of the RLTPR protein underpin its essential role for costimulation via CD28 in mouse and human T cells

M. Malissen , R. Roncagalli , M. Cucchetti , E. Bergot , N. Jarmuzynski , et al.
European Journal of Immunology, 2016, 46 (1, SI), pp.22-23
Article dans une revue hal-01438157v1
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CD5, an Undercover Regulator of TCR Signaling

Guillaume Voisinne , Anne Gonzalez De Peredo , Romain Roncagalli
Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.02900⟩
Article dans une revue hal-02089002v1
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Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discrimination

Guillaume Voisinne , Marie Locard-Paulet , Carine Froment , Emilie Maturin , Marisa Goncalves Menoita , et al.
Nature Immunology, 2022, ⟨10.1038/s41590-022-01288-x⟩
Article dans une revue hal-03767648v1
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Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

Javier Celis-Gutierrez , Peter Blattmann , Yunhao Zhai , Nicolas Jarmuzynski , Kilian Ruminski , et al.
Cell Reports, 2019, 27 (11), pp.3315+. ⟨10.1016/j.celrep.2019.05.041⟩
Article dans une revue hal-02359439v1

The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4(+) T cells

Guillaume Gaud , Romain Roncagalli , Karima Chaoui , Isabelle Bernard-Cadenat , Julien Familiades , et al.
Science Signaling, 2018, 11 (538), ⟨10.1126/scisignal.aar3083⟩
Article dans une revue hal-02117993v1

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

Romain Roncagalli , Margot Cucchetti , Nicolas Jarmuzynski , Claude Grégoire , Elise Bergot , et al.
Journal of Experimental Medicine, 2016, 213 (11), pp.2437-2457. ⟨10.1084/jem.20160579⟩
Article dans une revue hal-01455791v1
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Proteomic Analysis of the SH2Domain-containing Leukocyte Protein of 76 kDa (SLP76) Interactome

Yacine Bounab , Anne-Marie- Hesse , Bruno Iannascoli , Luca Grieco , Yohann Couté , et al.
Molecular and Cellular Proteomics, 2013, 12 (10), pp.2874-2889. ⟨10.1074/mcp.M112.025908⟩
Article dans une revue hal-02086260v1
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Cis interactions between CD2 and its ligands on T cells are required for T cell activation

Bin Li , Yan Lu , Ming-Chao Zhong , Jin Qian , Rui Li , et al.
Science Immunology, 2022, 7 (74), ⟨10.1126/sciimmunol.abn6373⟩
Article dans une revue hal-03867882v1
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Computational Modeling of the Main Signaling Pathways Involved in Mast Cell Activation

Anna Niarakis , Yacine Bounab , Luca Grieco , Romain Roncagalli , Anne-Marie Hesse , et al.
Marc Daëron; Falk Nimmerjahn. Fc Receptors, 382, Springer, pp.69-93, 2014, Current Topics in Microbiology and Immunology, 978-3-319-07911-0. ⟨10.1007/978-3-319-07911-0_4⟩
Chapitre d'ouvrage hal-02086273v1

Fit αβ T-Cell Receptor suppresses leukemogenesis of Pten-deficient thymocytes.

Stéphanie Gon , Marie Loosveld , Thomas Crouzet , Delphine Potier , Mélanie Bonnet , et al.
Article dans une revue hal-01772992v1
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Systems-level conservation of the proximal TCR signaling network of mice and humans

Philippe Nicolas , Jocelyn Ollier , Daiki Mori , Guillaume Voisinne , Javier Celis-Gutierrez , et al.
Journal of Experimental Medicine, 2022, 219 (2), pp.e20211295. ⟨10.1084/jem.20211295⟩
Article dans une revue inserm-03554390v1

Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.

Michael Mingueneau , Romain Roncagalli , Claude Grégoire , Adrien Kissenpfennig , Arkadiusz Miazek , et al.
Immunity, 2009, 31 (2), pp.197-208. ⟨10.1016/j.immuni.2009.05.013⟩
Article dans une revue hal-00432068v1

Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.

Magali Grange , Marilyn Giordano , Amandine Mas , Romain Roncagalli , Guylène Firaguay , et al.
Immunology, 2015, 145 (4), pp.543-57. ⟨10.1111/imm.12471⟩
Article dans une revue inserm-01420012v1

Quantitative analysis of Vav1 signalosome in primary CD4 T cells identify several new Vav1 partners including CD226

G. Gaud , R. Roncagalli , Gonzalez A. de Pedro , Bernard Malissen , A. Saoudi
European Journal of Immunology, 2016, 46 (1, SI), pp.24-25
Article dans une revue hal-01438156v1

Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry

Etienne Caron , Romain Roncagalli , Takeshi Hase , Witold E. Wolski , Meena Choi , et al.
Cell Reports, 2017, 18 (13), pp.3219-3226. ⟨10.1016/j.celrep.2017.03.019⟩
Article dans une revue hal-01996176v1

Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes.

Romain Roncagalli , Michael Mingueneau , Claude Grégoire , Christelle Langlet , Bernard Malissen , et al.
Seminars in Immunopathology, 2010, 32 (2), pp.117-25. ⟨10.1007/s00281-009-0195-y⟩
Article dans une revue istex hal-00553492v1

Toward an integrative biology of T cells and dendritic cells

M. Malissen , R. Roncagalli , S. Henri , M. Dalod , H. Luche
European Journal of Immunology, 2016, 46 (1, SI), pp.44
Article dans une revue hal-01438138v1
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The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation

Daiki Mori , Claude Gregoire , Guillaume Voisinne , Javier Celis-Gutierrez , Rudy Aussel , et al.
Journal of Experimental Medicine, 2020, 218, ⟨10.1084/jem.20201011⟩
Article dans une revue hal-03013448v1
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Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation

Guillaume Voisinne , Antonio García-Blesa , Karima Chaoui , Frédéric Fiore , Elise Bergot , et al.
Molecular Systems Biology, 2016, 12, pp.876. ⟨10.15252/msb.20166837⟩
Article dans une revue inserm-01368500v1
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LymphoAtlas: a dynamic and integrated phosphoproteomic resource of TCR signaling in primary T cells reveals ITSN 2 as a regulator of effector functions

Marie Locard‐paulet , Guillaume Voisinne , Carine Froment , Marisa Goncalves Menoita , Youcef Ounoughene , et al.
Molecular Systems Biology, 2020, 16 (7), pp.e9524. ⟨10.15252/msb.20209524⟩
Article dans une revue hal-02981035v1

LAT signaling pathology: an "autoimmune" condition without T cell self-reactivity.

Romain Roncagalli , Michael Mingueneau , Claude Grégoire , Marie Malissen , Bernard Malissen
Trends in Immunology, 2010, 31 (7), pp.253-9. ⟨10.1016/j.it.2010.05.001⟩
Article dans une revue istex hal-00605842v1

CD6 modulates thymocyte selection and peripheral T cell homeostasis

Marc Orta-Mascaro , Marta Consuegra-Fernandez , Esther Carreras , Romain Roncagalli , Amado Carreras-Sureda , et al.
Journal of Experimental Medicine, 2016, 213 (8), pp.1387-1397. ⟨10.1084/jem.20151785⟩
Article dans une revue hal-01438134v1
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Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics

Guillaume Voisinne , Kristof Kersse , Karima Chaoui , Liaoxun Lu , Julie Chaix , et al.
Nature Immunology, 2019, 20 (11), pp.1530 - 1541. ⟨10.1038/s41590-019-0489-8⟩
Article dans une revue hal-03013469v1
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Opposing regulatory functions of the TIM3 (HAVCR2) signalosome in primary effector T cells as revealed by quantitative interactomics

Yunhao Zhai , Javier Celis-Gutierrez , Guillaume Voisinne , Daiki Mori , Laura Girard , et al.
Cellular and molecular immunology, In press, ⟨10.1038/s41423-020-00575-7⟩
Article dans une revue hal-03086942v1

The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4 + T cells

Guillaume Gaud , Romain Roncagalli , Karima Chaoui , Isabelle Bernard , Julien Familiades , et al.
Science Signaling, 2018, 11 (538), pp.eaar3083. ⟨10.1126/scisignal.aar3083⟩
Article dans une revue inserm-04284289v1

The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.

Michaël Mingueneau , Amandine Sansoni , Claude Grégoire , Romain Roncagalli , Enrique Aguado , et al.
Nature Immunology, 2008, 9 (5), pp.522-32. ⟨10.1038/ni.1608⟩
Article dans une revue istex hal-00294188v1
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In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation

Stéphanie O Morin , Valentin Giroux , Cédric Favre , Yassina Bechah , Nathalie Auphan-Anezin , et al.
Cellular and Molecular Life Sciences, 2015, pp.DOI 10.1007/s00018-015-1873-7. ⟨10.1007/s00018-015-1873-7⟩
Article dans une revue inserm-01122788v1