Subject of research
Solid state fluorescence ; Crystal Nucleation ; Microfluidic; Kinetics ; Spectroscopy;
Curriculum Vitae
Legal Status :
Born in 1958 March , 9th. Maried, three children.
Titles :
Agrégation de Sciences Physiques, June 1981
Physical Chemistry PhD, May 1988
Formation :
Lycée Louis le Grand Classes Préparatoires, Sept.1975-1977
ENS Saint Cloud, June 1977-1982
Université Paris Sud, 1983-1988
Post-Doctoral stay : IMS Okasaki, July 1988-Sept.1989
Position :
ENS Saint Cloud, June 1977-1982
Research Associate 2, 1983
Research Associate 1, 1989
Senior Researcher 2, 2001
Activities
We have developed a fluorescence lifetime imaging device (FLIM) under microscope. We count individual photons with a resolution of 50ps and 1024x1024. We can make video FLIM at a rate of 1000 image/second. With a probing laser, an excitation laser and a microfluidic mixing device we can study, photo-, thermo-, electro-, induced reactions after mixing. The molecules and the phases are characterized by their lifetime.
We apply this to the development of sensing nanoparticles, indeed if the exciton is free in a particle, that particle can be quenched by a single target. On the reverse, for lightening application localized excitons are preferred.
We claim that luminescence decays can be described by a Perrin Poisson model. The complexity of the decay is due to the distribution of the quenchers around the exciton but mainly to the small number of these quenchers. Any detection method with a high dynamic range can detect the small fraction of the excitons free of any quenching. This gives access to the number of quenchers independently of their quenching rate.
We are currently studying the ROS production par gold nanoparticles.
We are currently studying the nucleation and growth inside a microfluidic device induced by a laser. We shall observe the first nanoseconds of the birth of a crystal.