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Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer

Delphine Goehrig , Jérémy Nigri , Rémi Samain , Zhichong Wu , Paola Cappello , et al.
Gut, 2019, 68 (4), pp.693-707. ⟨10.1136/gutjnl-2018-317570⟩
Article dans une revue hal-02526963v1
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The Cellular and Biological Impact of Extracellular Vesicles in Pancreatic Cancer

Zainab Hussain , Jeremy Nigri , Richard Tomasini
Cancers, 2021, 13 (12), pp.3040. ⟨10.3390/cancers13123040⟩
Article dans une revue hal-03627331v1

Ketogenic HMG‐CoA lyase and its product β‐hydroxybutyrate promote pancreatic cancer progression

Victoire Gouirand , Tristan Gicquel , Evan Lien , Emilie Jaune‐pons , Quentin da Costa , et al.
EMBO Journal, 2022, ⟨10.15252/embj.2021110466⟩
Article dans une revue hal-03623502v1
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Pharmacological targeting of the protein synthesis mTOR/4E-BP1 pathway in cancer-associated fibroblasts abrogates pancreatic tumourchemoresistance

Camille Duluc , Siham Moatassim-Billah , Mounira Chalabi-Dchar , Aurélie Perraud , Rémi Samain , et al.
EMBO Molecular Medicine, 2015, pp.735-753
Article dans une revue hal-01208071v1
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Macrophages reprogramming driven by cancer-associated fibroblasts under FOLFIRINOX treatment correlates with shorter survival in pancreatic cancer

Zainab Hussain , Thomas Bertran , Pascal Finetti , Eugenie Lohmann , Emilie Mamessier , et al.
Cell Communication and Signaling, 2024, 22 (1), pp.1. ⟨10.1186/s12964-023-01388-7⟩
Article dans une revue hal-04390903v1

LDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma

Angélina Acier , Magali Godard , Fanny Gassiot , Pascal Finetti , Marion Rubis , et al.
Communications Biology, 2021, 4 (1), pp.987. ⟨10.1038/s42003-021-02508-0⟩
Article dans une revue hal-04235770v1
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Pancreatic preneoplastic lesions plasma signatures and biomarkers based on proteome profiling of mouse models

Laetitia Ligat , Nathalie Saint-Laurent , Aïcha El-Mrani , Véronique Gigoux , Talal Al Saati , et al.
British Journal of Cancer, 2015, 113 (11), pp.1590 - 1598. ⟨10.1038/bjc.2015.370⟩
Article dans une revue hal-01926958v1
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Dendrimer nanosystems for adaptive tumor-assisted drug delivery via extracellular vesicle hijacking

Yifan Jiang , Zhenbin Lyu , Brigino Ralahy , Juan Liu , Tom Roussel , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120, ⟨10.1073/pnas.2215308120⟩
Article dans une revue hal-03977439v1
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LIF Drives Neural Remodeling in Pancreatic Cancer and Offers a New Candidate Biomarker

Christian Bressy , Sophie Lac , Jérémy Nigri , Julie Leca , Julie Roques , et al.
Cancer Research, 2017, 78 (4), pp.909 - 921. ⟨10.1158/0008-5472.CAN-15-2790⟩
Article dans une revue hal-01789367v1
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Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages

Rémi Samain , Alexia Brunel , Thibaut Douché , Marjorie Fanjul , Stéphanie Cassant-Sourdy , et al.
Cellular and Molecular Gastroenterology and Hepatology, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩
Article dans une revue pasteur-03252986v1

PAP/REG3A favors perineural invasion in pancreatic adenocarcinoma and serves as a prognostic marker

Jérémy Nigri , Meritxell Gironella , Christian Bressy , Elena Vila-Navarro , Julie Roques , et al.
Cellular and Molecular Life Sciences, 2017, 74 (22), pp.4231 - 4243. ⟨10.1007/s00018-017-2579-9⟩
Article dans une revue hal-01788470v1
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LDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma.

Angélina Acier , Magali Godard , Fanny Gassiot , Pascal Finetti , Marion Rubis , et al.
Communications Biology, 2021, 4 (1), pp.987. ⟨10.1038/s42003-021-02508-0⟩
Article dans une revue hal-03452855v1
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Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions

Orianne Olivares , Jared R Mayers , Victoire Gouirand , Margaret E Torrence , Tristan Gicquel , et al.
Nature Communications, 2017, 8, ⟨10.1038/ncomms16031⟩
Article dans une revue hal-01788014v1

Pharmacological targeting of the protein synthesis mTOR /4E‐ BP 1 pathway in cancer‐associated fibroblasts abrogates pancreatic tumour chemoresistance

Camille Duluc , Siham Moatassim‐billah , Mounira Chalabi‐dchar , Aurélie Perraud , Rémi Samain , et al.
EMBO Molecular Medicine, 2015, 7 (6), pp.735-753. ⟨10.15252/emmm.201404346⟩
Article dans une revue hal-02421448v1
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Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling

Elodie Roger , Sylvie Martel , Adrien Bertrand-Chapel , Arnaud Depollier , Nicolas Chuvin , et al.
Cell Death and Disease, 2019, 10 (12), pp.886. ⟨10.1038/s41419-019-2116-x⟩
Article dans une revue hal-02533109v1

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma

Fabienne Guillaumond , Julie Leca , Orianne Olivares , Marie-Noëlle Lavaut , Nicolas Nvidal@mnhn.Fr Vidal , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (10), pp.3919--3924. ⟨10.1073/pnas.1219555110⟩
Article dans une revue hal-01460466v1
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Crosstalk between TAp73 and TGF-β in fibroblast regulates iNOS expression and Nrf2-dependent gene transcription

Aimeric Cabrié , Olivier Guittet , Richard Tomasini , Philippe Vincendeau , Michel Lepoivre
Free Radical Biology and Medicine, 2019, 134, pp.617-629. ⟨10.1016/j.freeradbiomed.2019.02.008⟩
Article dans une revue hal-02169935v1

Hypoxia Induced Tumor Metabolic Switch Contributes to Pancreatic Cancer Aggressiveness

Sophie Vasseur , Richard Tomasini , Roselyne Tournaire , Juan Iovanna
Cancers, 2010, 2 (4), pp.2138-2152. ⟨10.3390/cancers2042138⟩
Article dans une revue hal-03562728v1
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DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification

Clémentine Decamps , Alexis Arnaud , Florent Petitprez , Mira Ayadi , Aurélia Baurès , et al.
BMC Bioinformatics, 2021, 22 (1), pp.473. ⟨10.1186/s12859-021-04381-4⟩
Article dans une revue hal-03372668v1

FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer

Sonia Zaghdoudi , Emilie Decaup , Ismahane Belhabib , Rémi Samain , Stéphanie Cassant-Sourdy , et al.
EMBO Molecular Medicine, 2020, 12 (11), ⟨10.15252/emmm.202012010⟩
Article dans une revue hal-03032260v1

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness.

Julie Leca , Sébastien Martinez , Sophie Lac , Jérémy Nigri , Veronique Secq , et al.
Journal of Clinical Investigation, 2016, 126 (11), pp.4140-4156. ⟨10.1172/JCI87734⟩
Article dans une revue hal-01408056v1

Dendritic cell-based vaccination: powerful resources of immature dendritic cells against pancreatic adenocarcinoma

Aurelie Collignon , Francoise Silvy , Stephane Robert , Malika Trad , Sebastien Germain , et al.
OncoImmunology, 2018, 7 (12), ⟨10.1080/2162402X.2018.1504727⟩
Article dans une revue hal-02067477v1
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SK2 channels set a signalling hub bolstering CAF-triggered tumourigenic processes in pancreatic cancer

Raphael Rapetti-Mauss , Jérémy Nigri , Camille Berenguier , Pascal Finetti , Sarah Simha Tubiana , et al.
Gut, 2023, 72 (4), pp.722-735. ⟨10.1136/gutjnl-2021-326610⟩
Article dans une revue hal-04257740v1
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Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma

Carole Siret , Aurélie Dobric , Anna Martirosyan , Chloé Terciolo , Sébastien Germain , et al.
British Journal of Cancer, 2018, 118 (4), pp.546 - 557. ⟨10.1038/bjc.2017.411⟩
Article dans une revue hal-01788519v1

Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A

Yajie Zhao , Zhichong Wu , Marie Chanal , Fabienne Guillaumond , Delphine Goehrig , et al.
Cancer Research, 2020, 80 (16), pp.3359-3371. ⟨10.1158/0008-5472.CAN-19-3763⟩
Article dans une revue hal-03008999v1
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Stiffness-induced cancer-associated fibroblasts are responsible for immunosuppression in a platelet-derived growth factor ligand-dependent manner

Pia Gamradt , Kevin Thierry , Melissa Masmoudi , Zhichong Wu , Hector Hernandez-Vargas , et al.
PNAS Nexus, 2023, 2 (12), ⟨10.1093/pnasnexus/pgad405⟩
Article dans une revue hal-04373776v1
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Thery , Kenneth Witwer , Elena Aikawa , Maria Jose Alcaraz , Johnathon Anderson , et al.
Journal of Extracellular Vesicles, 2018, 7 (1), pp.1535750. ⟨10.1080/20013078.2018.1535750⟩
Article dans une revue hal-02323217v1