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Researcher identifiers

Production year

Co-authors

Number of documents

3

Publications of Richard Galinier


I am leading research projects dealing with immunobiological interactions in host/pathogen systems. Goals are a) the identification and characterization of key molecules involved in pathogen virulence and host resistance, b) to decipher the mechanisms of invertebrate immunity at the molecular and evolution levels, c) to fight against the disease caused by studied pathogens.

Our experimental approaches are mainly comparative analyses of genes and proteins expression between different environmental or experimental conditions, at both individual and population levels. I am also interested by the functional validation of candidate protein identified.

My expertise domain concern transcriptomic and proteomic approaches. At the transcriptomic level: nucleic acid extraction, PCR, cloning, mutagenesis, real time PCR, library construction (EST, microsatellite, substractive,…), in situ hybridization, RNA-Seq and Sanger sequencing analyses, microsatellite multiplex analyses. At the proteomic level: protein 1D electrophoresis, western blot, immunoprecipitation, heterologous and cell free expression system, protein purification system, interactome approach.

 

For more information:

http://ihpe.univ-perp.fr/en/ihpe-galinier-richard-english/


2017    "Guillaume Mitta"   

Journal articles3 documents

  • Anaïs Portet, Silvain Pinaud, Guillaume Tetreau, Richard Galinier, Céline Cosseau, et al.. Integrated multi-omic analyses in Biomphalaria-Schistosoma dialogue reveal the immunobiological significance of FREP- Sm PoMuc interaction. Developmental and Comparative Immunology, Elsevier, 2017, 75, pp.16 - 27. ⟨10.1016/j.dci.2017.02.025⟩. ⟨hal-01598455⟩
  • C. Adema, L. Hillier, C. Jones, E.S. Loker, M. Knight, et al.. Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications, Nature Publishing Group, 2017, 8, pp.15451. ⟨10.1038/ncomms15451⟩. ⟨hal-01523953⟩
  • Richard Galinier, Emmanuel Roger, Yves Moné, David Duval, Anaïs Portet, et al.. A multistrain approach to studying the mechanisms underlying compatibility in the interaction between Biomphalaria glabrata and Schistosoma mansoni. PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (3), pp.e0005398. ⟨10.1371/journal.pntd.0005398.s005⟩. ⟨hal-01511153⟩