Researcher identifiers

Co-authors

Number of documents

27

Publications of Richard Galinier


I am leading research projects dealing with immunobiological interactions in host/pathogen systems. Goals are a) the identification and characterization of key molecules involved in pathogen virulence and host resistance, b) to decipher the mechanisms of invertebrate immunity at the molecular and evolution levels, c) to fight against the disease caused by studied pathogens.

Our experimental approaches are mainly comparative analyses of genes and proteins expression between different environmental or experimental conditions, at both individual and population levels. I am also interested by the functional validation of candidate protein identified.

My expertise domain concern transcriptomic and proteomic approaches. At the transcriptomic level: nucleic acid extraction, PCR, cloning, mutagenesis, real time PCR, library construction (EST, microsatellite, substractive,…), in situ hybridization, RNA-Seq and Sanger sequencing analyses, microsatellite multiplex analyses. At the proteomic level: protein 1D electrophoresis, western blot, immunoprecipitation, heterologous and cell free expression system, protein purification system, interactome approach.

 

For more information:

http://ihpe.univ-perp.fr/en/ihpe-galinier-richard-english/


Journal articles26 documents

  • Annia Alba, David Duval, Jorge Sánchez, Ana Perez, Silvain Pinaud, et al.. The immunobiological interplay between Pseudosuccinea columella resistant/susceptible snails with Fasciola hepatica: Hemocytes in the spotlight. Developmental & Comparative Immunology, 2020, 102, pp.103485. ⟨10.1016/j.dci.2019.103485⟩. ⟨hal-02279344⟩
  • Anaïs Portet, Silvain Pinaud, Cristian Chaparro, Richard Galinier, Nolwenn Dheilly, et al.. Sympatric versus allopatric evolutionary contexts shape differential immune response in Biomphalaria / Schistosoma interaction. PLoS Pathogens, Public Library of Science, 2019, 15 (3), pp.e1007647. ⟨10.1371/journal.ppat.1007647⟩. ⟨hal-02076267⟩
  • Silvain Pinaud, Anaïs Portet, Jean-François Allienne, Lucid Belmudes, Cécile Saint-Beat, et al.. Molecular characterisation of immunological memory following homologous or heterologous challenges in the schistosomiasis vector snail, Biomphalaria glabrata. Developmental and Comparative Immunology, Elsevier, 2019, 92, pp.238-252. ⟨hal-01952235⟩
  • Anaïs Portet, Richard Galinier, Silvain Pinaud, Julien Portela, Fanny Nowacki, et al.. BgTEP: an antiprotease involved in innate immune sensing in Biomphalaria glabrata. Frontiers in Immunology, Frontiers, 2018, 9, pp.1206. ⟨10.1101/308130⟩. ⟨hal-01838951⟩
  • Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve Toulza, Caroline Montagnani, et al.. Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters. Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.4215. ⟨10.1038/s41467-018-06659-3⟩. ⟨hal-01898110⟩
  • Guillaume Tetreau, Silvain Pinaud, Anaïs Portet, Richard Galinier, Benjamin Gourbal, et al.. Specific Pathogen Recognition by Multiple Innate Immune Sensors in an Invertebrate. Frontiers in Immunology, Frontiers, 2017, 8, pp.1249. ⟨10.3389/fimmu.2017.01249⟩. ⟨hal-01729395⟩
  • Laurent Héritier, David Duval, Richard Galinier, Anne-Leila Meistertzheim, Olivier Verneau. Oxidative stress induced by glyphosate-based herbicide on freshwater turtles. Environmental Toxicology and Chemistry, Wiley, 2017, 36 (12), pp.3343 - 3350. ⟨10.1002/etc.3916⟩. ⟨hal-01808555⟩
  • Richard Galinier, Guillaume Tetreau, Anaïs Portet, Silvain Pinaud, David Duval, et al.. First characterization of viruses from freshwater snails of the genus Biomphalaria , the intermediate host of the parasite Schistosoma mansoni. Acta Tropica, Elsevier, 2017, 167, pp.196-203. ⟨hal-01988464⟩
  • Richard Galinier, Guillaume Tetreau, Anaïs Portet, Silvain Pinaud, David Duval, et al.. First characterization of viruses from freshwater snails of the genus Biomphalaria, the intermediate host of the parasite Schistosoma mansoni. Acta Tropica, Elsevier, 2017, 167, pp.196-203. ⟨10.1016/j.actatropica.2016.12.021⟩. ⟨hal-01435053⟩
  • Anaïs Portet, Silvain Pinaud, Guillaume Tetreau, Richard Galinier, Céline Cosseau, et al.. Integrated multi-omic analyses in Biomphalaria-Schistosoma dialogue reveal the immunobiological significance of FREP- Sm PoMuc interaction. Developmental and Comparative Immunology, Elsevier, 2017, 75, pp.16 - 27. ⟨10.1016/j.dci.2017.02.025⟩. ⟨hal-01598455⟩
  • C. Adema, L. Hillier, C. Jones, E.S. Loker, M. Knight, et al.. Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications, Nature Publishing Group, 2017, 8, pp.15451. ⟨10.1038/ncomms15451⟩. ⟨hal-01523953⟩
  • Richard Galinier, Emmanuel Roger, Yves Moné, David Duval, Anaïs Portet, et al.. A multistrain approach to studying the mechanisms underlying compatibility in the interaction between Biomphalaria glabrata and Schistosoma mansoni. PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (3), pp.e0005398. ⟨10.1371/journal.pntd.0005398.s005⟩. ⟨hal-01511153⟩
  • Silvain Pinaud, Julien Portela, David Duval, Fanny Nowacki,, Marie-Aude Olive, et al.. A Shift from Cellular to Humoral Responses Contributes to Innate Immune Memory in the Vector Snail Biomphalaria glabrata. PLoS Pathogens, Public Library of Science, 2016, 12 (1), pp.e1005361. ⟨10.1371/journal.ppat.1005361⟩. ⟨hal-01259482⟩
  • Jérôme Boissier, Sébastien Grech-Angelini, B. L. Webster, Jean-François Allienne, Tine Huyse, et al.. Outbreak of urogenital schistosomiasis in Corsica (France): an epidemiological case study. The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2016, 16 (8), pp.971-979. ⟨10.1016/S1473-3099(16)00175-4⟩. ⟨hal-01364002⟩
  • Nolwenn M Dheilly, Fanny Maure, Marc Ravallec, Richard Galinier, Josée Doyon, et al.. Who is the puppet master? Replication of a parasitic wasp-associated virus correlates with host behaviour manipulation. Proceedings of the Royal Society B: Biological Sciences, Royal Society, The, 2015, 282 (1803), pp.20142773. ⟨10.1098/rspb.2014.2773⟩. ⟨hal-01141139⟩
  • Nolwenn M Dheilly, David Duval, Gabriel Mouahid, Rémi Emans, Jean-François Allienne, et al.. A family of variable immunoglobulin and lectin domain containing molecules in the snail Biomphalaria glabrata. Developmental and Comparative Immunology, Elsevier, 2015, 48 (1), pp.234-243. ⟨10.1016/j.dci.2014.10.009⟩. ⟨hal-01082870⟩
  • David Duval, Richard Galinier, Gabriel Mouahid, Eve Toulza, Jean-François Allienne, et al.. A Novel Bacterial Pathogen of Biomphalaria glabrata: A Potential Weapon for Schistosomiasis Control?. PLoS Neglected Tropical Diseases, Public Library of Science, 2015, 9 (2), pp.e0003489. ⟨10.1371/journal.pntd.0003489.s002⟩. ⟨hal-01162649⟩
  • Richard Galinier, Julien Portela, Yves Moné, Jean-François Allienne, Hélène Henri, et al.. Biomphalysin, a new β pore-forming toxin involved in Biomphalaria glabrata immune defense against Schistosoma mansoni.. PLoS Pathogens, Public Library of Science, 2013, 9 (3), pp.e1003216. ⟨10.1371/journal.ppat.1003216⟩. ⟨halsde-00823685⟩
  • Julien Portela, David Duval, Anne Rognon, Richard Galinier, Jérôme Boissier, et al.. Evidence for Specific Genotype-Dependent Immune Priming in the Lophotrochozoan Biomphalaria glabrata Snail.. Journal of Innate Immunity, Karger, 2013, 5 (3), pp.261-276. ⟨10.1159/000345909⟩. ⟨halsde-00790554⟩
  • Rodrigue Mintsa Nguema, Juliette Langand, Richard Galinier, Mohamed A Idris, Mahmoud A Shaban, et al.. Genetic diversity, fixation and differentiation of the freshwater snail Biomphalaria pfeifferi (Gastropoda, Planorbidae) in arid lands.. Genetica, Springer Verlag, 2013, 141, pp.171-184. ⟨10.1007/s10709-013-9715-8⟩. ⟨halsde-00823688⟩
  • Richard Galinier, Steven Van Beurden, Elsa Amilhat, Jeannette Castric, Guy Schoehn, et al.. Complete genomic sequence and taxonomic position of eel virus European X (EVEX), a rhabdovirus of European eel.. Virus Res, 2012, 166 (1-2), pp.1-12. ⟨10.1016/j.virusres.2012.02.020⟩. ⟨halsde-00700373⟩
  • Gabriel Mouahid, Rodrigue Mintsa Nguema, M.A. Idris, M.A. Shaban, S. Al Yafee, et al.. High phenotypic frequencies of complete albinism in wild populations of Biomphalaria pfeifferi (Gastropoda: Pulmonata). Malacologia, 2010, 53 (1), pp.161-166. ⟨halsde-00608656⟩
  • Mathieu Badets, Guillaume Mitta, Richard Galinier, Olivier Verneau. Expression patterns of Abd-A/Lox4 in a monogenean parasite with alternative developmental paths.. Molecular and Biochemical Parasitology, Elsevier, 2010, 173 (2), pp.154-157. ⟨10.1016/j.molbiopara.2010.05.011⟩. ⟨halsde-00504771⟩
  • Emmanuel Roger, Christoph Grunau, Raymond Pierce, Hirohisa Hirai, Benjamin Gourbal, et al.. Controlled chaos of polymorphic mucins in a metazoan parasite (Schistosoma mansoni) interacting with its invertebrate host (Biomphalaria glabrata).. PLoS Neglected Tropical Diseases, Public Library of Science, 2008, 2 (11), pp.e330. ⟨10.1371/journal.pntd.0000330⟩. ⟨halsde-00344615⟩
  • François Guillou, Guillaume Mitta, Richard Galinier, Christine Coustau. Identification and expression of gene transcripts generated during an anti-parasitic response in Biomphalaria glabrata.. Developmental and Comparative Immunology, Elsevier, 2007, 31 (7), pp.657-71. ⟨10.1016/j.dci.2006.10.001⟩. ⟨hal-00170685⟩
  • Richard Galinier, Evelyne Gout, Hugues Lortat-Jacob, Jonathan Wood, Jadwiga Chroboczek. Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases.. Biochemistry, American Chemical Society, 2002, 41 (48), pp.14299-305. ⟨hal-01061430⟩

Poster communications1 document