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	Pour les 25 documents Envoyer sur ORCID RSS ATOM Exporter BibTeX XML-TEI CSV RTF EndNote PDF HTML Export avancé	Page :	triés par Pertinence Auteur A→Z Auteur Z→A Titre A→Z Titre Z→A Date de publication croissante Date de publication décroissante Date de dépôt croissante Date de dépôt décroissante

		Design, synthesis and antimalarial activity of novel, quinoline-Based, zinc metallo-aminopeptidase inhibitors Marian Flipo , Isabelle Florent , Philippe Grellier , Christian Sergheraert , Rebecca Déprez-Poulain Bioorganic and Medicinal Chemistry Letters, 2003, 13 (16), pp.2659-2662. ⟨10.1016/S0960-894X(03)00550-X⟩ Article dans une revue mnhn-02867485v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry Benoit Deprez , Damien Bosc , Julie Charton , Cyril Couturier , Rebecca Deprez-Poulain , et al. Molecules, 2021, 26 (19), pp.6083. ⟨10.3390/molecules26196083⟩ Article dans une revue hal-04465890v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Novel Selective Inhibitors of the Zinc Plasmodial Aminopeptidase PfA-M1 as Potential Antimalarial Agents Marion Flipo , Terence Beghyn , Virginie Leroux , Isabelle Florent , Benoit Déprez , et al. Journal of Medicinal Chemistry, 2007, 50 (6), pp.1322-1334. ⟨10.1021/jm061169b⟩ Article dans une revue istex mnhn-02904302v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Chimie thérapeutique et chémobiologie. Rebecca Déprez , Frédéric Schmidt , Brigitte Lesur L'Actualité Chimique, 2021 Article dans une revue hal-03514288v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors Rébecca F. Déprez-Poulain , Marion Flipo , Catherine Piveteau , Florence Leroux , Sandrine Dassonneville , et al. Journal of Medicinal Chemistry, 2012, 55 (24), pp.10909-10917. ⟨10.1021/jm301506h⟩ Article dans une revue hal-03051765v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Solvent-free microwave-assisted Meyers’ lactamization Mouhamad Jida , Rebecca Deprez-Poulain , Sandra Malaquin , Pascal Roussel , Francine Agbossou-Niedercorn , et al. Green Chemistry, 2010, 12, pp.961-964. ⟨10.1039/b924111f⟩ Article dans une revue istex hal-02269383v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis of a 200-member library of squaric acid N-hydroxylamide amides. Julie Charton , Benoît P. Déprez , Rébecca F. Déprez-Poulain Bioorganic and Medicinal Chemistry Letters, 2008, 18 (18), pp.4968-71. ⟨10.1016/j.bmcl.2008.08.025⟩ Article dans une revue istex inserm-00323821v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates Alice Legru , Federica Verdirosa , Yen Vo-Hoang , Giusy Tassone , Filippo Vascon , et al. Journal of Medicinal Chemistry, 2022, 65 (24), pp.16392-16419. ⟨10.1021/acs.jmedchem.2c01257⟩ Article dans une revue hal-03978634v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice Rebecca Déprez-Poulain , Nathalie Hennuyer , Damien Bosc , Wenguang Liang , Emmanuelle Enée , et al. Nature Communications, 2015, 6 (8250), ⟨10.1038/ncomms9250⟩ Article dans une revue hal-02511111v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening Florence Leroux , Damien Bosc , Terence Beghyn , Paul Hermant , Sandrine Warenghem , et al. European Journal of Medicinal Chemistry, 2019, 179, pp.557-566. ⟨10.1016/j.ejmech.2019.06.057⟩ Article dans une revue hal-03243182v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds. Julie Charton , Lise Charruault , Rebecca Déprez-Poulain , Benoit Déprez Combinatorial Chemistry and High Throughput Screening, 2008, 11 (4), pp.294-303. ⟨10.2174/138620708784246013⟩ Article dans une revue inserm-00281198v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A simple reaction to produce small structurally complex and diverse molecules Rebecca Deprez-Poulain , Nicolas Willand , Christophe Boutillon , Guy Nowogrocki , Nathalie Azaroual , et al. Tetrahedron Letters, 2004, 45 (27), pp.5287-5290. ⟨10.1016/j.tetlet.2004.05.008⟩ Article dans une revue inserm-00110443v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Discovery, Structure–Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5 Sylvain Picon , Rajaa Boulahjar , Vanessa Hoguet , Morgane Baron , Isabelle Duplan , et al. Journal of Medicinal Chemistry, 2023, ⟨10.1021/acs.jmedchem.2c01881⟩ Article dans une revue hal-04192205v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis, Antimalarial Activity, and Molecular Modeling of New Pyrrolo[1,2- a ]quinoxalines, Bispyrrolo[1,2- a ]quinoxalines, Bispyrido[3,2- e ]pyrrolo[1,2- a ]pyrazines, and Bispyrrolo[1,2- a ]thieno[3,2- e ]pyrazines Jean Guillon , Philippe Grellier , Mehdi Labaied , Pascal Sonnet , Jean-Michel Léger , et al. Journal of Medicinal Chemistry, 2004, 47 (8), pp.1997-2009. ⟨10.1021/jm0310840⟩ Article dans une revue istex mnhn-02867477v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Insulin-Degrading Enzyme, an Under-Estimated Potential Target to Treat Cancer? Laetitia Lesire , Florence Leroux , Rebecca Déprez-Poulain , Benoit Deprez Cells, 2022, 11 (7), pp.1228. ⟨10.3390/cells11071228⟩ Article dans une revue hal-03657094v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease Florent Letronne , Geoffroy Laumet , Anne-Marie Ayral , Julien Chapuis , Florie Demiautte , et al. EBioMedicine, 2016, 9, pp.278-292. ⟨10.1016/j.ebiom.2016.06.002⟩ Article dans une revue hal-02155738v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis and in Vitro and in Vivo Antimalarial Activity of N 1 -(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives Adina Ryckebusch , Rebecca Déprez-Poulain , Louis Maes , Marie-Ange Debreu-Fontaine , Elisabeth Mouray , et al. Journal of Medicinal Chemistry, 2003, 46 (4), pp.542-557. ⟨10.1021/jm020960r⟩ Article dans une revue istex mnhn-02867486v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives. Julie Charton , Rebecca Deprez-Poulain , Nathalie Hennuyer , Anne Tailleux , Bart Staels , et al. Bioorganic and Medicinal Chemistry Letters, 2009, 19 (2), pp.489-92. ⟨10.1016/j.bmcl.2008.11.040⟩ Article dans une revue inserm-00360276v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Kinetic Target-Guided Synthesis: Reaching the Age of Maturity Damien Bosc , Virgyl Camberlein , Ronan Gealageas , Omar Castillo-Aguilera , Benoit Deprez , et al. Journal of Medicinal Chemistry, 2019, 63 (8), pp.3817-3833. ⟨10.1021/acs.jmedchem.9b01183⟩ Article dans une revue hal-03051818v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Identification of indole-based activators of insulin degrading enzyme Nicolas Kraupner , Chau Phi Dinh , Xiaoan Wen , Valérie Landry , Adrien Herledan , et al. European Journal of Medicinal Chemistry, 2021, pp.113982. ⟨10.1016/j.ejmech.2021.113982⟩ Article dans une revue hal-03430475v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Hydroxamates: Relationships between Structure and Plasma Stability Marion Flipo , Julie Charton , Akila Hocine , Sandrine Dassonneville , Benoit Deprez , et al. Journal of Medicinal Chemistry, 2009, 52 (21), pp.6790-6802. ⟨10.1021/jm900648x⟩ Article dans une revue hal-03051799v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening. Marion Flipo , Terence Beghyn , Julie Charton , Virginie A. Leroux , Benoit Déprez , et al. Bioorganic and Medicinal Chemistry, 2007, 15 (1), pp.63-76. ⟨10.1016/j.bmc.2006.10.010⟩ Article dans une revue istex inserm-00323832v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Drug Target Engagement using coupled Cellular Thermal Shift Assay -acoustic Reverse Phase Protein Array Adrien Herledan , Marine Andres , Aurore Lejeune-Dodge , Florence Leroux , Alexandre Biela , et al. Slas Discovery, 2019, 25 (2), pp.207-214. ⟨10.1177/2472555219897256⟩ Article dans une revue hal-03051837v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox Paul Hermant , Damien Bosc , Catherine Piveteau , Ronan Gealageas , Baovy Lam , et al. Journal of Medicinal Chemistry, 2017, 60 (21), pp.9067-9089. ⟨10.1021/acs.jmedchem.7b01444⟩ Article dans une revue hal-03054238v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Modulators of hERAP2 discovered by High-Throughput Screening Laura Medve , Ronan Gealageas , Vy Lam Bao , Valentin Guillaume , Omar Castillo-Aguilera , et al. European Journal of Medicinal Chemistry, 2020, 211, pp.113053. ⟨10.1016/j.ejmech.2020.113053⟩ Article dans une revue hal-03059990v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More

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Design, synthesis and antimalarial activity of novel, quinoline-Based, zinc metallo-aminopeptidase inhibitors

Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry

Novel Selective Inhibitors of the Zinc Plasmodial Aminopeptidase PfA-M1 as Potential Antimalarial Agents

Chimie thérapeutique et chémobiologie.

Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors

Solvent-free microwave-assisted Meyers’ lactamization

Synthesis of a 200-member library of squaric acid N-hydroxylamide amides.

Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening

Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds.

A simple reaction to produce small structurally complex and diverse molecules

Discovery, Structure–Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5

Synthesis, Antimalarial Activity, and Molecular Modeling of New Pyrrolo[1,2- a ]quinoxalines, Bispyrrolo[1,2- a ]quinoxalines, Bispyrido[3,2- e ]pyrrolo[1,2- a ]pyrazines, and Bispyrrolo[1,2- a ]thieno[3,2- e ]pyrazines

Insulin-Degrading Enzyme, an Under-Estimated Potential Target to Treat Cancer?

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

Synthesis and in Vitro and in Vivo Antimalarial Activity of N 1 -(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.

Kinetic Target-Guided Synthesis: Reaching the Age of Maturity

Identification of indole-based activators of insulin degrading enzyme

Hydroxamates: Relationships between Structure and Plasma Stability

A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening.

Drug Target Engagement using coupled Cellular Thermal Shift Assay -acoustic Reverse Phase Protein Array

Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox

Modulators of hERAP2 discovered by High-Throughput Screening