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63

Pierre Sibille


Titulaire d'un doctorat en Immunologie j'exerce depuis 1997 dans le domaine des interactions Hôte-pathogène. Depuis maintenant 10 ans, mes activités de recherche concernent l'étude eds déterminants structuraux qui gouvernent le tropisme de différentes souches de prions.  Mon expertise concerne principalement l'immunologie, la biochimie et la biophysique des interactions hôte-pathogène


Journal articles28 documents

  • Iman Al-Dybiat, Mohammed Moudjou, Davy Martin, Fabienne Reine, Laetitia Herzog, et al.. Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures. Scientific Reports, Nature Publishing Group, 2019, 9 (1), 14 p. ⟨10.1038/s41598-019-51084-1⟩. ⟨hal-02627362⟩
  • Angelique Egalon, Vincent Beringue, Human Rezaei, Pierre Sibille. Prion Strains and Transmission Barrier Phenomena. Pathogens, MDPI, 2018, 7 (1), ⟨10.3390/pathogens7010005⟩. ⟨hal-02626379⟩
  • Mohammed Moudjou, Jerome Chapuis, Meriem Mekrouti, Fabienne Reine, Laetitia Herzog, et al.. Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification. Scientific Reports, Nature Publishing Group, 2016, 6, ⟨10.1038/srep29116⟩. ⟨hal-02629949⟩
  • Danica Ciric, Charles-Adrien Richard, Mohammed Moudjou, Jerome Chapuis, Pierre Sibille, et al.. Interaction between Shadoo and PrP Affects the PrP-Folding Pathway. Journal of Virology, American Society for Microbiology, 2015, 89 (12), pp.6287-6293. ⟨10.1128/JVI.03429-14⟩. ⟨hal-02636090⟩
  • Mohammed Moudjou, Pierre Sibille, Guillaume Fichet, Fabienne Reine, Jerome Chapuis, et al.. Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification. mBio, American Society for Microbiology, 2014, 5 (1), ⟨10.1128/mBio.00829-13⟩. ⟨hal-02636078⟩
  • - Thien-Phong Vu Manh, Hélène Marty, Pierre Sibille, Yves Le Vern, Bernd Kaspers, et al.. Existence of conventional dendritic cells in Gallus gallus revealed by comparative gene expression profiling. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2014, 192 (10), pp.4510-4517. ⟨10.4049/jimmunol.1303405⟩. ⟨hal-02640822⟩
  • Pascale Quéré, Josette Pierre, My Dung Hoang, Evelyne Esnault, Jorge Domenech, et al.. Presence of dendritic cells in chicken spleen cell preparations and their functional interaction with the parasite Toxoplasma gondii. Veterinary Immunology and Immunopathology, Elsevier, 2013, 153 (1-2), pp.57-69. ⟨10.1016/j.vetimm.2013.02.007⟩. ⟨hal-02648390⟩
  • Florent Laferrière, Philippe Tixador, Mohammed Moudjou, Jerome Chapuis, Pierre Sibille, et al.. Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics. PLoS Pathogens, Public Library of Science, 2013, 9 (10), ⟨10.1371/journal.ppat.1003702⟩. ⟨hal-02650542⟩
  • Vincent Beringue, Laetitia Herzog, Emilie Jaumain, Fabienne Reine, Pierre Sibille, et al.. Facilitated cross-species transmission of prions in extraneural tissue. Science, American Association for the Advancement of Science, 2012, 335 (6067), pp.472-475. ⟨10.1126/science.1215659⟩. ⟨hal-01019814⟩
  • Nicolas Lebonvallet, Christine Jeanmaire, Louis Danoux, Pierre Sibille, Gilles Pauly, et al.. The evolution and use of skin explants: potential and limitations for dermatological research.. European Journal of Dermatology, John Libbey Eurotext, 2010, 20 (6), pp.671-84. ⟨10.1684/ejd.2010.1054⟩. ⟨hal-00946758⟩
  • Iciar Munoz, Magali Berges, Claire Bonsergent, Fleur Aline, Pascale Quéré, et al.. Cloning, expression and functional characterization of chicken CCR6 and its ligand CCL20. Molecular Immunology, Elsevier, 2009, 47 (2-3), pp.551-559. ⟨10.1016/j.molimm.2009.07.010⟩. ⟨hal-02656782⟩
  • B.E.F. Gourbal, Frédéric Guillou, G. Mitta, P. Sibille, A. Théron, et al.. Excretory-secretory products of larval Fasciola hepatica investigated using a two-dimensional proteomic approach. Molecular and Biochemical Parasitology, Elsevier, 2008, 161 (1), pp.63-66. ⟨10.1016/j.molbiopara.2008.05.002⟩. ⟨halsde-00332385⟩
  • Irène Gabriel, S. Mallet, Pierre Sibille. La microflore digestive des volailles : facteurs de variation et conséquences pour l'animal. Productions animales, Institut National de la Recherche Agronomique, 2005, 18 (5), pp.309-322. ⟨hal-02681958⟩
  • Pierre Sibille, Omar Tliba, Chantal Boulard. Early and transient cytotoxic response of peritoneal cells from Fasciola hepatica-infected rats. Veterinary Research, BioMed Central, 2004, 35, pp.573-584. ⟨hal-02675045⟩
  • C. Boulard, Guanlin He, Pierre Sibille, H. Yin. Preface - Hypodermosis in China, Eu and Central Asia. Chinese Journal of Veterinary Parasitology, 2004, 12 (suppl.), n.p. ⟨hal-02671965⟩
  • Pierre Sibille, C. Boulard. Control of cattle grub in Europe. Chinese Journal of Veterinary Parasitology, 2004, 12 (suppl.), pp.106-110. ⟨hal-02672415⟩
  • S. Maes, Pierre Sibille, C. Boulard. Deer myiasis in France. Chinese Journal of Veterinary Parasitology, 2004, 12 (suppl.), pp.123-131. ⟨hal-02681898⟩
  • Pierre Sibille, Omar Tliba, Chantal Boulard. Early and transient cytotoxic response of peritoneal cells from Fasciola hepatica-infected rats. Veterinary Research, BioMed Central, 2004, 35 (5), pp.573-584. ⟨10.1051/vetres:2004033⟩. ⟨hal-00902797⟩
  • O. Tliba, Nathalie Moiré, Yves Le Vern, C. Boulard, A. Chauvin, et al.. Early hepatic immune response in rats infected with Fasciola hepatica. Veterinary Research, BioMed Central, 2002, 33, pp.261-270. ⟨hal-02676863⟩
  • O. Tliba, A. Chauvin, Yves Le Vern, C. Boulard, Pierre Sibille. Evaluation of the hepatic NK cell response during the early phase of Fasciola hepatica infection in rats. Veterinary Research, BioMed Central, 2002, 33, pp.327-332. ⟨hal-02677079⟩
  • O. Tliba, Pierre Sibille, C. Boulard, A. Chauvin. Early hepatic cytokine mRNA expression in experimental rat fasciolosis. Veterinary Parasitology, Elsevier, 2002, 103 (3), pp.237-349. ⟨hal-02673017⟩
  • V. Leriche, Pierre Sibille, B. Carpentier. Use of an enzyme-linked lectinsorbent assay to monitor the shift in polysaccharide composition in bacterial biofilms. Applied and Environmental Microbiology, American Society for Microbiology, 2000, 66 (5), pp.1851-1856. ⟨hal-02698447⟩
  • O. Tliba, Pierre Sibille, C. Boulard, A. Chauvin. Local hepatic immune response in rats during primary infection with Fasciola hepatica. Parasite, EDP Sciences, 2000, 7 (1), pp.9-18. ⟨10.1051/parasite/2000071009⟩. ⟨hal-02696964⟩
  • Cecile Calléja, K. Bigot, C. Eeckhoutte, Pierre Sibille, C. Boulard, et al.. Comparison of hepatic and renal drug-metabolising enzyme activities in sheep given single or two-fold challenge infections with Fasciola hepatica. International Journal for Parasitology, Elsevier, 2000, 30 (8), pp.953-958. ⟨hal-02695314⟩
  • Pierre Sibille, Cecile Calléja, Florence Carreras, K. Bigot, Pierre Galtier, et al.. Fasciola hepatica: influence of gender and liver biotransformations on flukicide treatment efficacy of rats infested and cured with either clorsulon/ivermectin or Triclabendazole. Experimental Parasitology, Elsevier, 2000, 94, pp.227-237. ⟨hal-02694634⟩
  • Pierre Sibille, Thérèse Ternynck, Faridabano Nato, Gérard Buttin, Donny Strosberg, et al.. Mimotopes of polyreactive anti-DNA antibodies identified using phage-display peptide libraries. European Journal of Immunology, Wiley-VCH Verlag, 1997, 27 (5), pp.1221-1228. ⟨10.1002/eji.1830270525⟩. ⟨hal-02696137⟩
  • Pierre Sibille, a D Strosberg. A FIV epitope defined by a phage peptide library screened with a monoclonal anti-FIV antibody. Immunology Letters, Elsevier, 1997, 59 (3), pp.133-137. ⟨10.1016/S0165-2478(97)00111-9⟩. ⟨hal-02699260⟩
  • Pierre Sibille, A. Avrameas, A. Moraillon, J. Richardson, P. Sonigo, et al.. Comparison of serological tests for the diagnosis of feline immunodeficiency virus infection of cats. Veterinary Microbiology, Elsevier, 1994, 45, pp.259-267. ⟨hal-02706916⟩

Conference papers27 documents

  • Françoise Bussière, Alisson Niepceron, Yves Le Vern, Alix Sausset, Sonia Lamandé, et al.. CCL20 production by Eimeria tenella infected chicken epithelial cells: a new mechanism to control the infection?. 34. Congrès du club d'étude des cellules épithéliales digestives (CECED), Mar 2017, Paris, France. ⟨hal-01602314⟩
  • Mohammed Moudjou, Jerome Chapuis, Meriem Mekrouti, Fabienne Reine, Laetitia Herzog, et al.. PrP glycosylation-independent amplification of prions using highly efficient cell-based protein misfolded cyclic amplification. Prion, Institut National de la Recherche Agronomique (INRA). FRA., 2016, PHILADELPHIA, United States. pp.1. ⟨hal-02738985⟩
  • Françoise Bussière, Marion Vergonjeanne, Alisson Niepceron, Sonia Lacroix Lamandé, Anne Silvestre, et al.. CCL20 production by Eimeria tenella infected chicken epithelial cells: a new mechanism to control the infection ?. 5. Journées d'animation scientifique de la FéRI, Fédération de recherche en infectiologie (FéRI)., Jul 2016, Tours, France. ⟨hal-02794437⟩
  • Mohammed Moudjou, Pierre Sibille, Guillaume Fichet, Fabienne Reine, Jerome Chapuis, et al.. Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification. International Prion Congress 2014, May 2014, Trieste, Italy. ⟨10.4161/pri.29370⟩. ⟨hal-02739413⟩
  • Pascale Quéré, Josette Pierre, My Dung Hoang, Evelyne Esnault, Jorge Domenech, et al.. Characterization of chicken adherent spleen cells and functional interaction with Toxoplasma gondii protozoan. 12. Avian Immunology Research Group Meeting (AIRG2012), BBSRC Roslin Institute. Edinburgh, GBR., Aug 2012, Edinburgh, United Kingdom. pp.36. ⟨hal-02749918⟩
  • Pascale Quéré, Pierre Sibille, Nicolas Bruneau, T.X. Toan, J.C. Maillard, et al.. Antibody response to H5N9 inactivated vaccine and MHC diversity in the chicken. 8. Journées du réseau francophone d'Immunologie des Animaux Domestiques (IAD), May 2011, Marcy l'Etoile, France. pp.20. ⟨hal-01001392⟩
  • Claire Bonsergent, Pierre Sibille, C. Bernard, Valérie Labas, Paul Langlois, et al.. Production de la chimiokine aviaire CCL20 en système CELO et potentiel adjuvant en liaison avec un fragment de l'hémagglutinine du virus influenza aviaire. 7. Rencontre du Réseau d'Immunologie des Animaux Domestiques (IAD), May 2010, Maisons-Alfort, France. 1 p. ⟨hal-02816430⟩
  • Bertrand Bed'Hom, Pascale Quéré, Pierre Sibille, Magalie Bergès, Nicolas Bruneau, et al.. Antibody response to H5N9 inactivated vaccine and MHC diversity in the chicken. XIth Meeting of the Avian Immunology Research Group, 2010, Budapest, Hungary. ⟨hal-02817298⟩
  • I. Munoz, Pascale Quéré, Pierre Sibille. Cloning, expression and functional characterization of chicken CCR6 and its ligand CCL20. Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Oct 2008, Nouzilly, France. 1 p. ⟨hal-02812923⟩
  • Pascale Quere, Josette Pierre, Paul Langlois, Pierre Sibille, Isabelle Dimier. Cellules dendritiques spléniques aviaires : résultats préliminaires d'isolement et de caractérisation. Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Oct 2008, Nouzilly, France. 1 p. ⟨hal-02823981⟩
  • Pascale Quéré, Josette Pierre, Paul Langlois, Pierre Sibille, Isabelle Dimier-Poisson. Characterization of chicken splenic dendritic cells and enrichment protocol to develop cell lines : preliminary results. Journée d'Animation du Réseau Immunologie des Animaux Domestiques (IAD), Oct 2008, Nouzilly, France. pp.Inconnu. ⟨hal-02824031⟩
  • Bertrand Bed'Hom, Nicolas Bruneau, Magali Berges, Pascale Quere, Pierre Sibille. Le niveau de la réponse vaccinale au virus influenza est déterminé par le génotype au CMH chez la poule.. Journées Scientifiques, Département de Génétique Animale, Apr 2008, Lacanau. ⟨hal-02751210⟩
  • I Munoz, Pascale Quéré, Pierre Sibille. Cloning, expression and functional characterization of chicken CCR6 and its ligand CCL20. 10th Avian Immunology Research Group Conference, 2008, Gold Coast, Australia. 1 p. ⟨hal-02813554⟩
  • Bertrand Bed'Hom, Nicolas Bruneau, Magali Berges, Pascale Quéré, Pierre Sibille. Le niveau de la réponse vaccinale au virus influenza est déterminé par le génotype au CMH chez la poule. Journées Scientifiques du Département Génétique Animale, 2008, Lacanau, France. 1 p. ⟨hal-02814827⟩
  • I Munoz, Pierre Sibille, Pascale Quéré. Clonage moléculaire et caractérisation de la chimiokine CCL20 et de son récepteur CCR6 chez le poulet. Journées d’Animation Scientifique du Département de Santé Animale, 2007, Tours, France. pp.Inconnu. ⟨hal-02813177⟩
  • Pierre Sibille, Christine Coustau. Do Digenean parasites use different or common strategies to escape intermediate and definitive host's immune response?, session 1 "From innate to adaptive immunity". 2nd European Veterinary Immunology Workshop, Sep 2006, Paris, France. ⟨hal-02752776⟩
  • Pierre Sibille, C. Boulard. Control of cattle grub in Europe. Hypodermosis in China, EU and Central Asia, Oct 2004, Lanzhou, China. ⟨hal-02828450⟩
  • O. Tliba, E. Khaznadji, M. Sabau, Nathalie Moiré, Pierre Sibille. Immune modulation by newly excysted juveniles of Fasciola hepatica. 5. Framework, Mar 2004, Bordeaux, France. ⟨hal-02762234⟩
  • Frédéric Lantier, Pierre Sibille. Création sur le centre Inra de Tours-Nouzilly d'une nouvelle animalerie en confinement P3 destinée aux ruminants et aux souris infectés par les agents des ESST ou par d'autres pathogènes. 3. Séminaire sur les Recherches engagées à l'INRA sur les ESST et les Prions, Feb 2003, Le Croisic, France. n.p. ⟨hal-02825917⟩
  • C. Boulard, Guanlin He, Pierre Sibille, H. Yin. Preface - Hypodermosis in China, Eu and Central Asia. Hypodermosis in China, EU and Central Asia, Oct 2001, Lanzhou, China. ⟨hal-02830118⟩
  • O. Tliba, Pierre Sibille, C. Boulard, A. Chauvin. Early hepatic immune response in Fasciola hepatica infected rats. 6. International Veterinary Immunology Symposium, Jul 2001, Uppsala, Sweden. ⟨hal-02762023⟩
  • Pierre Sibille, A. Chauvin. Isolation of an immunosuppressive fraction of adult F. hepatica excretion/secretion products using a Galanthus nivalis agglutinin. 6. International Veterinary Immunology Symposium, Jul 2001, Uppsala, Sweden. ⟨hal-02761938⟩
  • S. Maes, Pierre Sibille, C. Boulard. Deer myiasis in France. Hypodermosis in China, EU and Central Asia, Oct 2001, Lanzhou, China. ⟨hal-02827738⟩
  • E. Khaznadji, Nathalie Moiré, Pierre Sibille, Florence Carreras, C. Boulard, et al.. Réalisation d'une banque soustractive entre les stades juvéniles nouvellement excystés et adultes du parasite Fasciola hepatica. Forum de l'école doctorale, May 2000, Tours, France. ⟨hal-02770096⟩
  • O. Tliba, Pierre Sibille, C. Boulard, A. Chauvin. Caractérisation des ARNm des cytokines libérées localement durant la phase d'une infestation expérimentale par F. hepatica chez le rat. Congrès Annuel de la Société Française d'Immunologie, Nov 2000, Paris, France. pp.149. ⟨hal-02837984⟩
  • O. Tliba, Pierre Sibille, C. Boulard, A. Chauvin, . Université de Tours. Quantification des ARNm de cytokines chez le rat infesté expérimentalement par Fasciola hepatica (phase précoce). Forum de l'école doctorale, May 2000, Tours, France. ⟨hal-02769314⟩
  • Ginette Dambrine, M.C. Fauré, Pierre Sibille. La démarche qualité recherche à la PAP. 1. Rencontres de la qualité en recherche, Mar 2000, Draveil, France. ⟨hal-02769860⟩

Poster communications6 documents

  • Iman Al-Dybiat, Mohammed Moudjou, Fabienne Reine, Laetitia Herzog, Patricia Berthon, et al.. Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures. 11. Symposium of the French Domestic Animal Immunology Network (IAD 2018), Mar 2018, Tours, France. 56 p., 2018. ⟨hal-02737597⟩
  • Françoise Bussière, Alisson Niepceron, Sonia Lacroix Lamandé, Pierre Sibille, Pascale Quéré, et al.. CCL20 production by Eimeria tenella infected chicken epithelial cells: a new mechanism to control the infection ?. 14. Avian Immunology Research Group (AIRG) Meeting 2016, Sep 2016, Herrsching am Ammersee, Germany. 120 p., 2016. ⟨hal-02739230⟩
  • Pascale Quéré, Thien-Phong Vu Manh, Hélène Marty, Yves Le Vern, Pierre Sibille, et al.. Conventional dendrtitic cells are present in the chicken. 13. International Symposium on Dendritic Cells, Sep 2014, Tours, France. 2014, DC 2014. ⟨hal-02739720⟩
  • Florent Lafferiere, Philippe Tixador, Mohammed Moudjou, Jerome Chapuis, Pierre Sibille, et al.. Size, not density of strain-specific prion particles determines their replication dynamics. PRION 2013: Conquering Frontiers, May 2013, Banff, Alberta, Canada. Landes Bioscience, Prion, 7 (Suppl.), 2013. ⟨hal-02748301⟩
  • Pierre Sibille, Christine Coustau. Digenean parasites use common strategies to avoid intermediate and definitive hosts immune response. 16. European Congress of Immunology, Sep 2006, Paris, France. 1 p., 2006. ⟨hal-02814517⟩
  • Pierre Sibille, O. Tliba, Chantal Boulard. Early transient cytotoxic response of peritoneal cells from Fasciola hepatica-infected rats. European Workshop in Veterinary Immunology, Sep 2006, Paris, France. 1 p., 2006. ⟨hal-02812415⟩

Patents1 document

  • Alexandre Avraméas, Gianfranco Pancino, Pierre Sibille, Pierre Sonigo, Arthur Donny Strosberg. Fragment peptidique spécifique du virus de l'immunodéficience féline (FIV) et son utilisation comme réactif de diagnostic. France, N° de brevet: FR2721031 (A1). 1994. ⟨hal-03002362⟩

Habilitation à diriger des recherches1 document

  • Pierre Sibille. Habilitation à diriger les recherches. Sciences du Vivant [q-bio]. 2002. ⟨tel-02831273⟩