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Asymmetric α-Fluoroalkyl-α-Amino Acids: Recent Advances in Their Synthesis and Applications

Nathan Picois , Yazid Boutahri , Pierre Milbeo , Chiara Zanato , Nathalie Lensen , et al.
Molecules, 2024, 29 (6), pp.1408. ⟨10.3390/molecules29061408⟩
Article dans une revue hal-04516441v1

N-Pyrrolidine-based alpha/beta-peptides incorporating ABOC, a constrained bicyclic beta-amino acid, for asymmetric aldol reaction catalysis

Pierre Milbeo , Kelly Maurent , Laure Moulat , Aurelien Lebrun , Claude Didierjean , et al.
Tetrahedron, 2016, 72 (13), pp.1706-1715. ⟨10.1016/j.tet.2016.02.027⟩
Article dans une revue hal-01532027v1

C 1 -Symmetric 1,2-Diaminobicyclo[2.2.2]octane Ligands in Copper-Catalyzed Asymmetric Henry Reaction: Catalyst Development and DFT Studies

Pierre Milbeo , Laure Moulat , Claude Didierjean , Emmanuel Aubert , Jean Martinez , et al.
European Journal of Organic Chemistry, 2018, 2018 (2), pp.178-187. ⟨10.1002/ejoc.201701452⟩
Article dans une revue hal-02419329v1

Synthesis of Enantiopure 1,2-Diaminobicyclo[2.2.2]octane Derivatives, C 1 -Symmetric Chiral 1,2-Diamines with a Rigid Bicyclic Backbone

Pierre Milbeo , Laure Moulat , Claude Didierjean , Emmanuel Aubert , Jean Martinez , et al.
Journal of Organic Chemistry, 2017, 82 (6), pp.3144 - 3151. ⟨10.1021/acs.joc.7b00122⟩
Article dans une revue hal-01552321v1
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A bicyclic unit reversal to stabilize the 12/14-helix in mixed homochiral oligoureas

Pierre Milbeo , Matthieu Simon , Claude Didierjean , Emmanuel Wenger , Emmanuel Aubert , et al.
Chemical Communications, 2020, 56 (57), pp.7921-7924. ⟨10.1039/d0cc02902e⟩
Article dans une revue hal-03080580v1
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1-Aminobicyclo[2.2.2]octane-2-carboxylic acid and derivatives as chiral constrained bridged scaffolds for foldamers and chiral catalysts

Pierre Milbeo , Jean Martinez , Muriel Amblard , Monique Calmès , Baptiste Legrand
Accounts of Chemical Research, 2021, 54 (3), pp.685-696. ⟨10.1021/acs.accounts.0c00680⟩
Article dans une revue hal-03371473v1

12/10‐Helix in Mixed β‐Peptides Alternating Bicyclic and Acyclic β‐Amino Acids: Probing the Relationship between Bicyclic Side Chain and Helix Stability

Matthieu Simon , Pierre Milbeo , Hongtao Liu , Christophe Andre , Emmanuel Wenger , et al.
Chemistry - A European Journal, 2018, 24 (70), pp.18795-18800. ⟨10.1002/chem.201804404⟩
Article dans une revue hal-02403147v1
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Synthesis, characterisation and cytotoxic activity evaluation of new metal-salen complexes based on the 1,2-bicyclo[2.2.2]octane bridge

Pierre Milbeo , François Quintin , Laure Moulat , Claude Didierjean , Jean Martinez , et al.
Tetrahedron Letters, 2021, 63, pp.152706. ⟨10.1016/j.tetlet.2020.152706⟩
Article dans une revue hal-03103305v1