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Pierre LEBLOND

Pierre Leblond
137
Documents
Affiliations actuelles
Identifiants chercheurs

Présentation

**Bio** I received my PhD in molecular genetics in 1990 under the supervision of Prof. Bernard Decaris at Université Henri Poincaré in Nancy. Then, I did my military service (1 yr) as a scientist in the lab of Profs. I. Gresser and M. Tovey at Hôpital Paul Brousse (CNRS, Villejuif). Afterwards, I joined for 2 years Pr. J. Cullum at Kaiserslautern (Germany) thanks to EMBO and European Community fellowships. I was appointed to the position of Maître de Conférences at Université Henri Poincaré and was granted a professorship in 1995. Since then, I lead a research team; today named *Streptomyces Adaptation*, StrAda. In the past, I was director of the research unit from 2007 to 2018 (co-director from 2001 to 2007). At the national level, I sat at the National University Committee (CNU 65, cellular biology, 3 terms between 2004 and 2018). I sat in several instances of the Université de Lorraine (executive board, cluster council, faculty council). I was vice-president UL in charge of technology transfer in 2017-18, and currently project manager for the construction of a research building at the Faculty of Sciences. **Research** The guiding thread of all my research is to better understand the molecular mechanisms of bacterial genome evolution. Early in my career, I met *Streptomyces* and it became my pet bacteria. I developed methods (pulsed-field gel electrophoresis) and applied approaches (genome mapping, comparative genomics, genome mining) to study genome structure, organization and dynamics. Notably, I focused on recombination mechanisms shaping the genome (homologous and illegitimate recombination). Hence, these soil bacteria have to face variable environmental (biotic and abiotic parameters) conditions. They show an extraordinary capacity to adapt and to evolve through horizontal gene transfer. We currently study this dynamic in natural populations of *Streptomyces* (isolated from grains of forest soil) in terms of acquisition and diversification of new genes (secondary metabolite gene clusters, nutriment utilization, mobile genetic elements). **Teaching** I am teaching since 1989 in the field of genetics and microbiology in undergraduate and graduate courses. I continuously managed University programs; from 1995 to 2018 Licence de Biologie, Maîtrise de Génétique Moléculaire et Cellulaire, DESS Ressources Génomiques et Traitements Informatiques, Master de Microbiologie, Master Biotechnologies, Microbiologie, Aliment, Nutrition ; and founded several of them: DESS RGTI (2001), Master de Microbiologie (2008). I also contributed to the creation of the Cursus Master of Engineering (CMI ‘Biologie Santé Environnement’) in 2010 and supervised the cursus at its opening in 2012. Since 2018, I supervise the RIM (Research in Microbiology) orientation of the Master Microbiology (M2), a project-driven course in the omics field with full immersion in research laboratories. **Contact** E-mail : <pierre.leblond@univ-lorraine.fr> Téléphone : +33 (0)3 72 74 51 43 IdeHAL **pierre-leblond**

Publications

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Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS

Oyut Dagva , Annabelle Thibessard , Jean-Noël Lorenzi , Victor Labat , Emilie Piotrowski
Nucleic Acids Research, 2024, ⟨10.1093/nar/gkae132⟩
Article dans une revue hal-04495979v1
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Genome Analysis of a Variant of Streptomyces coelicolor M145 with High Lipid Content and Poor Ability to Synthetize Antibiotics

Thierry Dulermo , Clara Lejeune , Ece Aybeke , Sonia Abreu , Jean Bleton
Microorganisms, 2023, 11 (6), pp.1470. ⟨10.3390/microorganisms11061470⟩
Article dans une revue hal-04272608v1
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Ribosomal RNA operons define a central functional compartment in the Streptomyces chromosome

Jean-Noël Lorenzi , Annabelle Thibessard , Virginia S Lioy , Frédéric Boccard , Pierre Leblond
Nucleic Acids Research, 2022, 50 (20), pp.11654-11669. ⟨10.1093/nar/gkac1076⟩
Article dans une revue hal-03971411v1
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Subtelomeres are fast-evolving regions of the Streptomyces linear chromosome

Jean-Noël Lorenzi , Olivier Lespinet , Pierre Leblond , Annabelle Thibessard
Microbial Genomics, 2021, ⟨10.1099/mgen.0.000525⟩
Article dans une revue hal-03177250v2
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One-year follow-up of microbial diversity in bioaerosols emitted in a waste sorting plant in France

Jodelle Degois , Xavier Simon , Frédéric Clerc , Cyril Bontemps , Pierre Leblond
Waste Management, 2021, 120, pp.257-268. ⟨10.1016/j.wasman.2020.11.036⟩
Article dans une revue hal-03070350v1
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Elicitation of Antimicrobial Active Compounds by Streptomyces-Fungus Co-Cultures

Matthieu Nicault , Ali Zaiter , Stéphane Dumarcay , Patrick Chaimbault , Éric Gelhaye
Microorganisms, 2021, 9 (1), pp.178. ⟨10.3390/microorganisms9010178⟩
Article dans une revue hal-03112257v1
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Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation

Virginia S Lioy , Jean-Noel Lorenzi , Soumaya Najah , Thibault Poinsignon , Herve Leh
Nature Communications, 2021, 12, pp.5221. ⟨10.1038/s41467-021-25462-1⟩
Article dans une revue hal-03128776v2
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Negative Correlation between Lipid Content and Antibiotic Activity in Streptomyces: General Rule and Exceptions

Michelle David , Clara Lejeune , Sonia Abreu , Annabelle Thibessard , Pierre Leblond
Antibiotics, 2020, 9, pp.280. ⟨10.3390/antibiotics9060280⟩
Article dans une revue hal-02624260v1
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Mining the Biosynthetic Potential for Specialized Metabolism of a Streptomyces Soil Community

Matthieu Nicault , Abdoul-Razak Tidjani , Anthony Gauthier , Stéphane Dumarcay , Éric Gelhaye
Antibiotics, 2020, 9 (5), pp.271. ⟨10.3390/antibiotics9050271⟩
Article dans une revue hal-02619232v1
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Genome Sequences of Five Streptomyces Strains Isolated at Microscale

Matthieu Nicault , Abdoul-Razak Tidjani , Éric Gelhaye , Cyril Bontemps , Pierre Leblond
Microbiology Resource Announcements, 2020, 9 (23), ⟨10.1128/MRA.00428-20⟩
Article dans une revue hal-02801725v1
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Telomeric and sub-telomeric regions undergo rapid turnover within a Streptomyces population

Abdoul-Razak Tidjani , Cyril Bontemps , Pierre Leblond
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-63912-w⟩
Article dans une revue hal-02569171v1

Characterization of experimental complex fungal bioaerosols

Jodelle Degois , Xavier Simon , Cyril Bontemps , Pierre Leblond , Philippe Duquenne
Aerosol Science and Technology, 2019, 53 (2), pp.146-159. ⟨10.1080/02786826.2018.1557320⟩
Article dans une revue hal-02177356v1
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Bacterial NHEJ: A never ending story

Claire Bertrand , Annabelle Thibessard , Claude Bruand , François Lecointe , Pierre Leblond
Molecular Microbiology, 2019, ⟨10.1111/mmi.14218⟩
Article dans une revue hal-02044826v1

Clinical, Radiological, Histopathological, Molecular Description and Identification of Prognostic Factors for Desmoplastic Infantile Gangliogliomas and Astrocytomas: A Multicentric Cohort Study

A. Gourmel , R. Perbet , K. Beccaria , C. A. Maurage , F. Escande
Pediatric Blood and Cancer, 2019, 66 (4, SI), pp.S176-S177
Article dans une revue hal-03604454v1
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Massive Gene Flux Drives Genome Diversity between Sympatric Streptomyces Conspecifics

Abdoul-Razak Tidjani , Jean-Noël Lorenzi , Maxime Toussaint , Erwin van Dijk , Delphine Naquin
Article dans une revue hal-02278804v1
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Genome Sequences of 11 Conspecific Streptomyces sp. Strains

Abdoul-Razak Tidjani , Jean-Noël Lorenzi , Maxime Toussaint , Erwin van Dijk , Delphine Naquin
Microbiology Resource Announcements, 2019, 8 (38), ⟨10.1128/MRA.00863-19⟩
Article dans une revue hal-02292599v1
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Comparative Genomics among Closely Related Streptomyces Strains Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity

Cláudia M Vicente , Annabelle Thibessard , Jean-Noël Lorenzi , Mabrouka Benhadj , Laurence Hotel
Antibiotics, 2018, 7 (4), pp.86. ⟨10.3390/antibiotics7040086⟩
Article dans une revue hal-01887213v1

An aminoacylase activity from Streptomyces ambofaciens catalyzes the acylation of lysine on α-position and peptides on N-terminal position

Léna Dettori , Florent Ferrari , Xavier Framboisier , Cédric Paris , Yann Guiavarc’h
Engineering in Life Sciences, 2018, 18 (8), pp.589-599. ⟨10.1002/elsc.201700173⟩
Article dans une revue hal-01959650v1
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Diversité et activités antimicrobiennes de souches de Streptomyces de la Fetzara (Algérie)

Mabrouka Benhadj , Djamila Gacemi-Kirane , Maxime Toussaint , Laurence Hotel , Cyril Bontemps
Annales de Biologie Clinique, 2018, 76 (1), pp.81-95. ⟨10.1684/abc.2017.1316⟩
Article dans une revue hal-01844922v1
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Draft Whole-Genome Shotgun Sequence of Streptomyces sp. Strain ETH9427

Annabelle Thibessard , Cláudia M Vicente , Claire Bertrand , Bertrand Aigle , Pierre Leblond
Microbiology Resource Announcements, 2018, 7 (12), pp.e01197. ⟨10.1128/MRA.01197-18⟩
Article dans une revue hal-01887322v1
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Genome plasticity is governed by double strand break DNA repair in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond
Scientific Reports, 2018, 8 (1), pp.5272. ⟨10.1038/s41598-018-23622-w⟩
Article dans une revue hal-01757262v1
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Implication of RuvABC and RecG in homologous recombination in Streptomyces ambofaciens

Gregory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond
Research in Microbiology, 2017, 168 (1), pp.26-35. ⟨10.1016/j.resmic.2016.07.003⟩
Article dans une revue hal-01552147v1
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First metagenomic survey of the microbial diversity in bioaerosols emitted in waste sorting plants

Jodelle Degois , Frédéric Clerc , Xavier Simon , Cyril Bontemps , Pierre Leblond
Annals of Work Exposures and Health, 2017, 61 (9), pp.1076 - 1086. ⟨10.1093/annweh/wxx075⟩
Article dans une revue hal-01655252v1

Plasmid-like replication of a minimal streptococcal integrative and conjugative element

Nicolas Carraro , Virginie Libante , Florence Charron-Bourgoin , Gérard Guédon , Catherine Morel
Microbiology, 2016, 162 (4), pp.622 - 632. ⟨10.1099/mic.0.000219⟩
Article dans une revue hal-01476043v1
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Complete Genome Sequence of Streptomyces ambofaciens DSM 40697, a Paradigm for Genome Plasticity Studies.

Annabelle Thibessard , Pierre Leblond
Genome Announcements, 2016, 4 (3), ⟨10.1128/genomeA.00470-16⟩
Article dans une revue hal-01521992v1
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Multiple and Variable NHEJ-Like Genes Are Involved in Resistance to DNA Damage in Streptomyces ambofaciens

Grégory Hoff , Claire Bertrand , Lingli Zhang , Emilie Piotrowski , Ludovic Chipot
Frontiers in Microbiology, 2016, 7, pp.1901. ⟨10.3389/fmicb.2016.01901⟩
Article dans une revue hal-01521993v1
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Whole-cell biosensor of cellobiose and application to wood decay detection

Maxime Toussaint , Cyril Bontemps , Arnaud Besserer , Laurence Hotel , Philippe Gérardin
Journal of Biotechnology, 2016, 239, pp.39 - 46. ⟨10.1016/j.jbiotec.2016.10.003⟩
Article dans une revue hal-01655326v1

Role of secondary metabolites in the interaction between Pseudomonas fluorescensand soil microorganisms under iron-limited conditions

Aurélie Deveau , Harald Gross , Béatrice Palin , Samina Mehnaz , Max Schnepf
FEMS Microbiology Ecology, 2016, 92 (8), pp.1-11. ⟨10.1093/femsec/fiw107⟩
Article dans une revue hal-01490770v1

Construction of pDYN6902, a new Streptomyces integrative expression vector designed for cloning sequences interfering with Escherichia coli viability

Annabelle Thibessard , Claire Bertrand , Julien Hiblot , Emilie Piotrowski , Pierre Leblond
Plasmid, 2015, 82, pp.43-49. ⟨10.1016/j.plasmid.2015.10.003⟩
Article dans une revue hal-01258339v1
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Pseudomonas fluorescens Pirates both Ferrioxamine and Ferricoelichelin Siderophores from Streptomyces ambofaciens.

Justine Galet , Aurélie Deveau , Laurence Hotel , Pascale Frey-Klett , Pierre Leblond
Applied and Environmental Microbiology, 2015, 81 (9), pp.3132-3141. ⟨10.1128/AEM.03520-14⟩
Article dans une revue hal-01269032v1

Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer

Annabelle Thibessard , Drago Haas , Claude Gerbaud , Bertrand Aigle , Sylvie Lautru
Journal of Biotechnology, 2015, 214, pp.117-118. ⟨10.1016/j.jbiotec.2015.09.020⟩
Article dans une revue hal-01258341v1

Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis

Lijiang Song , Luisa Laureti , Christophe Corre , Pierre Leblond , Bertrand Aigle
Journal of Antibiotics, 2014, 67 (1), pp.71 - 76. ⟨10.1038/ja.2013.119⟩
Article dans une revue hal-01474997v1
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A Single Sfp-Type Phosphopantetheinyl Transferase Plays a Major Role in the Biosynthesis of PKS and NRPS Derived Metabolites in Streptomyces ambofaciens ATCC23877

Robert Bunet , Ramona Riclea , Luisa Laureti , Laurence Hotel , Cedric Paris
PLoS ONE, 2014, 9 (1), pp.e87607. ⟨10.1371/journal.pone.0087607⟩
Article dans une revue hal-01272916v1

Genome mining of Streptomyces ambofaciens

Bertrand Aigle , Sylvie Lautru , Dieter Spiteller , Jeroen S. Dickschat , Gregory L. Challis
Journal of Industrial Microbiology and Biotechnology, 2014, 41 (2), pp.251 - 263. ⟨10.1007/s10295-013-1379-y⟩
Article dans une revue hal-01475037v1

Gluconic acid-producing Pseudomonas sp. prevent γ-actinorhodin biosynthesis by Streptomyces coelicolor A3(2)

Justine Galet , Aurélie Deveau , Laurence Hotel , Pierre Leblond , Pascale Frey-Klett
Archives of Microbiology, 2014, 196 (9), pp.619-627. ⟨10.1007/s00203-014-1000-4⟩
Article dans une revue hal-01268576v1
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The adnAB Locus, Encoding a Putative Helicase-Nuclease Activity, Is Essential in Streptomyces

L. Zhang , Cong Tu Nguyen , L. Chipot , E. Piotrowski , C. Bertrand
Journal of Bacteriology, 2014, 196 (14), pp.2701 - 2708. ⟨10.1128/JB.01513-14⟩
Article dans une revue hal-01474715v1

Taxonomic and functional diversity of Streptomyces in a forest soil

Cyril Bontemps , Maxime Toussaint , Pierre-Vincent Revol , Laurence Hotel , Mathilde Jeanbille
FEMS Microbiology Letters, 2013, 342 (2), pp.157 - 167. ⟨10.1111/1574-6968.12126⟩
Article dans une revue hal-01655681v1

Bacterial genome mining for novel natural product discovery

S. Song , L Laureti , P Gomez-Escribano , D Fox , V Yeo
Planta Medica, 2012, 78 (11), ⟨10.1055/s-0032-1320194⟩
Article dans une revue hal-01667347v1

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

Luisa Laureti , Lijiang Song , Sheng Huang , Christophe Corre , Pierre Leblond
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (15), pp.6258 - 6263. ⟨10.1073/pnas.1019077108⟩
Article dans une revue hal-02651598v1

In silico prediction of horizontal gene transfer in Streptococcus thermophilus

Catherine Eng , Annabelle Thibessard , Morten Danielsen , Thomas Bovbjerg Rasmussen , Jean-Francois Mari
Archives of Microbiology, 2011, 193 (4), pp.287-297. ⟨10.1007/s00203-010-0671-8⟩
Article dans une revue inria-00569081v1

Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of kinamycins

R. Bunet , L. Song , M. Vaz Mendez , C. Corre , L. Hotel
Journal of Bacteriology, 2011, 193 ((5)), pp. 1142-1153. ⟨10.1128/JB.01269-10⟩
Article dans une revue hal-00606766v1
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Differential regulation of two closely related integrative and conjugative elements from Streptococcus thermophilus

Nicolas Carraro , Virginie Libante , Catherine Morel , Bernard Decaris , Florence Charron-Bourgoin
BMC Microbiology, 2011, 11 (238), 13 p. ⟨10.1186/1471-2180-11-238⟩
Article dans une revue hal-02642537v1
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Diversity and Mobility of Integrative and Conjugative Elements in Bovine Isolates of Streptococcus agalactiae, S. dysgalactiae subsp dysgalactiae, and S. uberis

Marisa Haenni , Estelle Saras , Stephane Bertin , Pierre Leblond , Jean-Yves Madec
Applied and Environmental Microbiology, 2010, 76 (24), pp.7957 - 7965. ⟨10.1128/AEM.00805-10⟩
Article dans une revue hal-01637787v1
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A new data mining approach for the detection of bacterial promoters combining stochastic and combinatorial methods

Catherine Eng , Charu Asthana , Bertrand Aigle , Sébastien Hergalant , Jean-Francois Mari
Journal of Computational Biology, 2009, 16 (9), pp.1211-1225. ⟨10.1089/cmb.2008.0122⟩
Article dans une revue inria-00419969v1

An iterative nonribosomal peptide synthetase assembles the pyrrole-amide antibiotic congocidine in Streptomyces ambofaciens.

Maud Juguet , Sylvie Lautru , François-Xavier Francou , Sárka Nezbedová , Pierre Leblond
Chem Biol, 2009, 16 (4), pp.421-31. ⟨10.1016/j.chembiol.2009.03.010⟩
Article dans une revue hal-00379056v1
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Regulation of the Synthesis of the Angucyclinone Antibiotic Alpomycin in Streptomyces ambofaciens by the Autoregulator Receptor AlpZ and Its Specific Ligand

Robert Bunet , M. V. V Mendes , Nicolas Rouhier , Xiuhua Pang , L. Hotel
Journal of Bacteriology, 2008, 190 (9), pp.3293 - 3305. ⟨10.1128/JB.01989-07⟩
Article dans une revue hal-01659448v1
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SIGffRid: A tool to search for sigma factor binding sites in bacterial genomes using comparative approach and biologically driven statistics

Fabrice Touzain , Sophie Schbath , Isabelle Debled-Rennesson , Bertrand Aigle , Gregory Kucherov
BMC Bioinformatics, 2008, 9 (73), pp.on line. ⟨10.1186/1471-2105-9-73⟩
Article dans une revue inria-00580657v1

Intraspecific variability of the terminal regions of the Streptomyces ambofaciens

F. Choulet , A. Gallois , B. Aigle , S. Mangenot , C. Gerbaud
Journal of Bacteriology, 2006, 188, p 6599-6610
Article dans une revue hal-00101141v1
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Intraspecific Variability of the Terminal Inverted Repeats of the Linear Chromosome of Streptomyces ambofaciens

Frédéric Choulet , Alexandre Gallois , B. Aigle , Sophie Mangenot , Claude Gerbaud
Journal of Bacteriology, 2006, 188 (18), pp.6599 - 6610. ⟨10.1128/JB.00734-06⟩
Article dans une revue hal-01659064v1

Evolution of the terminal regions of the streptomyces linear chromosome

Frédéric Choulet , Bertrand Aigle , Alexandre Gallois , Sophie Mangenot , Claude Gerbaud
Molecular Biology and Evolution, 2006, 23 (12), pp.2361-2369. ⟨10.1093/molbev/msl108⟩
Article dans une revue hal-02661267v1

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877

Francisco Barona-Gómez , Sylvie Lautru , François-Xavier Francou , Pierre Leblond , Jean-Luc Pernodet
Microbiology, 2006, 152 (11), pp.3355-3366. ⟨10.1099/mic.0.29161-0⟩
Article dans une revue hal-02666177v1
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Involvement of AlpV, a New Member of the Streptomyces Antibiotic Regulatory Protein Family, in Regulation of the Duplicated Type II Polyketide Synthase alp Gene Cluster in Streptomyces ambofaciens

Bertrand Aigle , Xiuhua Pang , Bernard Decaris , Pierre Leblond
Journal of Bacteriology, 2005, 187 (7), pp.2491 - 2500. ⟨10.1128/JB.187.7.2491–2500.2005⟩
Article dans une revue hal-01659049v1
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Differential and Cross-Transcriptional Control of Duplicated Genes Encoding Alternative Sigma Factors in Streptomyces ambofaciens

Virginie Roth , Bertrand Aigle , Robert Bunet , Thomas Wenner , Céline Fourrier
Journal of Bacteriology, 2004, 186 (16), pp.5355 - 5365. ⟨10.1128/JB.186.16.5355–5365.2004⟩
Article dans une revue hal-01659043v1
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Functional Angucycline-Like Antibiotic Gene Cluster in the Terminal Inverted Repeats of the Streptomyces ambofaciens Linear Chromosome

Xiuhua Pang , Bertrand Aigle , Jean-Michel Girardet , Sophie Mangenot , Jean-Luc Pernodet
Antimicrobial Agents and Chemotherapy, 2004, 48 (2), pp.575 - 588. ⟨10.1128/AAC.48.2.575-588.2004⟩
Article dans une revue hal-01659031v1

End-to-end fusion of linear deleted chromosomes initiates a cycle of genome instability in Streptomyces ambofaciens

Thomas Wenner , Virginie Roth , Gilles Fischer , Céline Fourrier , Bertrand Aigle
Molecular Microbiology, 2003, 50 (2), pp.411-425. ⟨10.1046/j.1365-2958.2003.03698.x⟩
Article dans une revue hal-01659028v1

Spontaneous chromosome circularization and amplification of a new amplifiable unit of DNA belonging to the terminal inverted repeats in Streptomyces ambofaciens ATCC 23877.

Sibel Catakli , Axelle Andrieux , Pierre Leblond , Bernard Decaris , Annie Dary
Archives of Microbiology, 2003, 179 (6), pp.387-93. ⟨10.1007/s00203-003-0534-7⟩
Article dans une revue hal-01159934v1

Intragenomic and intraspecific polymorphism of the 16S–23S rDNA internally transcribed sequences of Streptomyces ambofaciens

Thomas Wenner , Virginie Roth , Bernard Decaris , Pierre Leblond
Microbiology, 2002, 148 (3), pp.633-642. ⟨10.1099/00221287-148-3-633⟩
Article dans une revue hal-01658777v1

DNA rearrangements at the extremities of the Streptomyces ambofaciens linear chromosome: Evidence for developmental control

Annie Dary , Patricia Martin , Thomas Wenner , Bernard Decaris , Pierre Leblond
Biochimie, 2000, 82 (1), pp.29-34. ⟨10.1016/S0300-9084(00)00348-5⟩
Article dans une revue hal-01659018v1
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Modulation of Lipid Metabolism and Spiramycin Biosynthesis in Streptomyces ambofaciens Unstable Mutants

Catherine Schauner , Annie Dary , Ahmed Lebrihi , Pierre Leblond , Christine Delorme
Applied and Environmental Microbiology, 1999, 65 (6), pp.2730-2737. ⟨10.1128/AEM.65.6.2730-2737.1999⟩
Article dans une revue hal-01658995v1

Modulation of lipid metabolism and spiramycin biosynthesis in Streptomyces ambofaciens unstable mutants

C. Schauner , A. Dary , A. Lebrihi , Pierre Leblond , Bernard Decaris
Applied and Environmental Microbiology, 1999, 65 (6), pp.2730-2737. ⟨10.1128/AEM.65.6.2730-2737.1999⟩
Article dans une revue hal-02693523v1
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Intraclonal polymorphism in the bacterium Streptomyces ambofaciens ATCC23877: evidence for a high degree of heterogeneity of the wild type clones

Patricia Martin , Annie Dary , Axelle André , Gilles Fischer , Pierre Leblond
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1999, 430 (1), pp.75-85. ⟨10.1016/S0027-5107(99)00149-9⟩
Article dans une revue hal-01659011v1
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Evolution of the linear chromosomal DNA in Streptomyces: is genomic variability developmentally modulated?

Annie Dary , Patricia Martin , Thomas Wenner , Pierre Leblond , Bernard Decaris
Research in Microbiology, 1999, 150 (7), pp.439-445
Article dans une revue hal-01659000v1
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Chromosomal arm replacement generates a high level of intraspecific polymorphism in the terminal inverted repeats of the linear chromosomal DNA of Streptomyces ambofaciens

Gilles Fischer , Thomas Wenner , Bernard Decaris , Pierre Leblond
Proceedings of the National Academy of Sciences of the United States of America, 1998, 7 (6), pp.14296-301. ⟨10.1073/pnas.95.24.14296⟩
Article dans une revue hal-01625341v1

Chromosome geometry and intraspecific genetic polymorphism in Gram-positive bacteria revealed by pulsed-field gel electrophoresis (minireview)

Pierre Leblond , Bernard Decaris
Electrophoresis, 1998, 19 (4), pp.582 - 588. ⟨10.1002/elps.1150190420⟩
Article dans une revue hal-01658981v1
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Replication of the linear chromosomal DNA from the centrally located oriC of Streptomyces ambofaciens revealed by PFGE gene dosage analysis

Gilles Fischer , Anne-Catherine Holl , Jean Nicolas Volff , Dominique Vandewiele , Bernard Decaris
Research in Microbiology, 1998, 149 (3), pp.203-210. ⟨10.1016/S0923-2508(98)80080-6⟩
Article dans une revue hal-01658988v1
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Genetic instabi|ity and its possible evolutionary implications on the chromosomal structure of Streptomyces

Gilles Fischer , A Kyriacou , Bernard Decaris , Pierre Leblond
Biochimie, 1997, 79, pp.555 - 558. ⟨10.1016/S0300-9084(97)82003-2⟩
Article dans une revue hal-01658975v1

Characterization of two Streptomyces ambofaciens recA mutants: identification of the RecA protein by immunoblotting

B. Aigle , Anne Catherine Holl , Jaime F. Angulo , Pierre Leblond , Bernard Decaris
FEMS Microbiology Letters, 1997, 149, pp.181-7. ⟨10.1111/j.1574-6968.1997.tb10326.x⟩
Article dans une revue hal-01658772v1

Mapping of the ribosomal operons on the linear chromosomal DNA of Streptomyces ambofaciens DSM40697

F. Berger , G. Fischer , A. Kyriacou , Bernard Decaris , Pierre Leblond
FEMS Microbiology Letters, 1996, 143, pp.167-173
Article dans une revue hal-02687566v1

The unstable region of Streptomyces ambiofaciens includes 210 kb terminal inverted repeats flanking the extremities of the linear chromosomal DNA

Pierre Leblond , G. Fischer , X. Francou , F. Berger , M. Guérineau
Molecular Microbiology, 1996, 19 (2), pp.261-271
Article dans une revue hal-02697136v1

The unstable region of Streptomyces ambofaciens includes 210 kb terminal inverted repeats flanking the extremities of the linear chromosomal DNA

Pierre Leblond , Gilles Fischer , François-Xavier Francou , Franca Berger , Michel Guérineau
Molecular Microbiology, 1996, pp.261-71. ⟨10.1046/j.1365-2958.1996.366894.x⟩
Article dans une revue hal-01658762v1

Mapping of the ribosomal operons on the linear chromosomal DNA of Streptomyces ambofaciens DSM40697

Franca Berger , Gilles Fischer , Adamantini Kyriacou , Bernard Decaris , Pierre Leblond
FEMS Microbiology Letters, 1996, pp.167-73. ⟨10.1111/j.1574-6968.1996.tb08476.x⟩
Article dans une revue hal-01658770v1

Streptomyces: l'instabilité est aux bouts du chromosome

Pierre Leblond , Bernard Decaris
Bulletin - Société Française de Microbiologie, 1994, 9 (2), n.p
Article dans une revue hal-02702159v1

New insights into the genetic instability of streptomyces

Pierre Leblond , Bernard Decaris
FEMS Microbiology Letters, 1994, 123 (3), pp.225-32
Article dans une revue hal-01658755v1

New insights into the genetic instability of streptomyces

Pierre Leblond , Bernard Decaris
FEMS Microbiology Letters, 1994, 123, pp.225-232
Article dans une revue hal-02702659v1
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Physical Map of the Streptomyces lividans 66 Genome and Comparison with That of the Related Strain Streptomyces coelicolor A3(2)

Pierre Leblond , Matfihias Redenbach , John Cullum
Journal of Bacteriology, 1993, 175 (11), pp.3422 - 3429
Article dans une revue hal-01659214v1

The Streptomyces lividans 66 chromosome contains a 1 MB deletogenic region flanked by two amplifiable regions

R Redenbach , F Flett , P Piendl , I Glocker , R Rauland
Molecular and General Genetics MGG, 1993, 241 (3-4), pp.255-62
Article dans une revue hal-01659218v1

Analysis of genome instability in Streptomyces ambofaciens

Dominique Schneider , Bertrand Aigle , Pierre Leblond , Jean-Marc Simonet , Bernard Decaris
Journal of general microbiology, 1993, 139 (11), pp.2559-2567. ⟨10.1099/00221287-139-11-2559⟩
Article dans une revue hal-01658593v1
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A chromosomal hotspot for multiple rearrangements associated with genetic instability of Streptomyces ambofaciens DSM 40697

Philippe Demuyter , Dominique Schneider , Pierre Leblond , Jean-Marc Simonet , Bernard Decaris
Journal of general microbiology, 1991, 137 (3), pp.491 - 499. ⟨10.1099/00221287-137-3-491⟩
Article dans une revue hal-01658584v1
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Genetic Instability and Associated Genome Plasticity in Streptomyces ambofaciens: Pulsed-Field Gel Electrophoresis Evidence for Large DNA Alterations in a Limited Genomic Region

Pierre Leblond , Philippe Demuyter , Jean-Marc Simonet , Bernard Decaris
Journal of Bacteriology, 1991, 173 (13), pp.4229 - 4233
Article dans une revue hal-01658749v1

Pulsed-field gel electrophoresis analysis of the genome of Streptomyces ambofaciens strains

Pierre Leblond , F X Francou , J M Simonet , B Decaris
FEMS Microbiology Letters, 1990, pp.79-88
Article dans une revue hal-01658692v1

Genetic instability and hypervariability in Streptomyces ambofaciens: towards an understanding of a mechanism of genome plasticity

P. Leblond , P. Demuyter , J. M. Simonet , B. Decaris
Molecular Microbiology, 1990, 4 (5), pp.707 - 714. ⟨10.1111/j.1365-2958.1990.tb00641.x⟩
Article dans une revue hal-01658674v1
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Hypervariability, a New Phenomenon of Genetic Instability, Related to DNA Amplification in Streptomyces ambofaciens

Pierre Leblond , Philippe Demuyter , Laurence Moutier , Mohamed Laakel , Bernard Decaris
Journal of Bacteriology, 1989, 171 (1), pp.419-423. ⟨10.1128/jb.171.1.419-423.1989⟩
Article dans une revue hal-01658652v1
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Characterization of Two Families of Spontaneously Amplifiable Units of DNA in Streptomyces ambofaciens

P. Demuyter , P. Leblond , B. Decaris , J.-M. Simonet
Microbiology, 1988, 134 (7), pp.2001 - 2007. ⟨10.1099/00221287-134-7-2001⟩
Article dans une revue hal-01658578v1

Nonhomologous End-Joining in Bacteria

Annabelle Thibessard , Claire Bertrand , Edward J Bartlett , Aidan J Doherty , Claude Bruand
Joseph Jez. Encyclopedia of Biological Chemistry 3rd Edition,, 4, Elsevier, 2021, 9780128194607
Chapitre d'ouvrage hal-03319644v1

Evolution Underway in Prokaryotes

Sébastien Wielgoss , Pierre Leblond , Catherine Masson-Boivin , Philippe Normand
Sébastien Wielgoss; Pierre Leblond; Catherine Masson-Boivin; Philippe Normand. Prokaryotes and Evolution, Springer International Publishing, pp.339-391, 2019, 978-3-319-99784-1. ⟨10.1007/978-3-319-99784-1_6⟩
Chapitre d'ouvrage hal-02477674v1

Subtelomere Plasticity in the Bacterium Streptomyces

Annabelle Thibessard , Pierre Leblond
Edward J Louis, Marion M Becker. Subtelomeres, Springer Berlin Heidelberg, pp.243-258, 2013, 978-3-642-41565-4. ⟨10.1007/978-3-642-41566-1_14⟩
Chapitre d'ouvrage hal-01478830v1

Genome-guided Exploration of Streptomyces ambofaciens Secondary Metabolism

Bertrand Aigle , Robert Bunet , Christophe Corre , Amélie Garenaux , S. Huang
Paul J Dyson Institute of Life Sciences, School of Medicine, Swansea, UK. Streptomyces: Molecular Biology and Biotechnology, Caister Academic Press, Chapter 10 pp. 179-194, 2011, 978-1-904455-77-6
Chapitre d'ouvrage hal-01667184v1
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Using Markov Models to Mine Temporal and Spatial Data

Jean-Francois Mari , Florence Le Ber , El-Ghali Lazrak , Marc Benoît , Catherine Eng
Kimito Funatsu and Kiyoshi Hasegawa. New Fundamental Technologies in Data Mining, Intech, pp.561--584, 2011, 978-953-307-547-1
Chapitre d'ouvrage inria-00566801v1
Image document

Fouille de données du génome à l'aide de modèles de Markov cachés

Sébastien Hergalant , Bertrand Aigle , Pierre Leblond , Jean-François Mari
Extraction et gestion des connaissances. EGC 2005, Cépaduès, 2005, Revue des Nouvelles Technologies de l'Information, 2-85428-677-4 2-85428-682-0 (vol. 1) 2-85428-683-9 (vol. 2)
Chapitre d'ouvrage hal-02832934v1

PFGE: électrophorèse en champs pulsés (pulse field electrophoresis)

Pierre Leblond
INRA. Principes des techniques de biologie moléculaire, INRA Editions, pp.152-153, 2004, 9782738010674
Chapitre d'ouvrage hal-01659763v1

Unstable Linear Chromosomes: the Case of Streptomyces

Pierre Leblond , Bernard Decaris
Robert L Charlebois. Organization of the prokaryotic genome, ASM Press, pp.235-262, 1999, 1-55581-151-5
Chapitre d'ouvrage hal-01659748v1

Gene flux and chromosomal recombination as key drivers of adaptability and population functioning of Streptomyces

Pierre Leblond
Actino 2020 Journées des actinobactéries (en ligne), Dec 2020, Paris, France
Communication dans un congrès hal-03059295v1

Genome dynamics of the Streptomyces genus

Jean-Noël Lorenzi , Olivier Lespinet , Pierre Leblond , Annabelle Thibessard
ACTINO 2020 - Journées des actinobactéries, Dec 2020, Gif-sur-Yvette, France
Communication dans un congrès hal-03060006v1

Diversity and mobility of conjugative elements in a population of Streptomyces isolated from a rhizospheric micro-habitat.

Caroline Choufa , Anthony Gauthier , Manar Harb , Vos Michiel , Cyril Bontemps
Journées des Actinobactéries 2020 - ACTINO 2020, Dec 2020, Conférence virtuelle Gif Sur Yvette, France
Communication dans un congrès hal-03060874v1

Suivi sur une année de la biodiversité microbienne dans les bioaerosols émis dans un centre de tri des déchets

Jodelle Degois , Frédéric Clerc , Simon Xavier , Cyril Bontemps , Pierre Leblond
Congrès français sur les aérosols 2018 (CFA), Jan 2018, Paris, France
Communication dans un congrès hal-01582590v1

Massive gene fluxes in bacterial population fuels adaptation to soil forest ecosystem

Abdoul-Razak Tidjani , Jean-Noël Lorenzi , Olivier Lespinet , Cyril Bontemps , Pierre Leblond
Functional Ecology Conference Nancy 2018, Dec 2018, Nancy, France
Communication dans un congrès hal-02306656v1

Decipher and exploit interactions between bacteria and fungi to identify new bioactive metabolites

Matthieu Nicault , Cyril Bontemps , Éric Gelhaye , Pierre Leblond
Séminaire LUE Impact/Biomolécules du futur : de la découverte aux applications, May 2018, Nancy, France
Communication dans un congrès hal-03216629v1

Micro-time scale genome evolution among natural populations of Streptomyces

Maxime Toussaint , Abdoul-Razak Tidjani , Jean-Noël Lorenzi , Laurence Hotel , Olivier Lespinet
International Symposium of the Biology of Actinomycetes, May 2017, Jeju, South Korea
Communication dans un congrès hal-01625360v1

One year follow up of microbial biodiversity in French waste sorting plant

J Degois , F. Clerc , X. Simon , C Bontemps , Pierre Leblond
9th International Symposium on Modern Principles of Air Monitoring and Biomonitoring (AIRMON 2017), Jun 2017, Dresden, Germany
Communication dans un congrès hal-01657806v1

Evolution génomique au sein d'une population naturelle de Streptomyces

Abdoul-Razak Tidjani , Maxime Toussaint , Jean-Noël Lorenzi , Laurence Hotel , Olivier Lespinet
Actino2017 Journées des Actinobactéries, Oct 2017, Lyon, France
Communication dans un congrès hal-01655238v1

Double strand break repair triggers genome plasticity in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond
Actino2017 Journées des Actinobactéries, Oct 2017, Lyon, France
Communication dans un congrès hal-01655543v1

Searching For Specialized Metabolites Gene Clusters By Mining Genomic Islands: A New Comparative Genomics-Based Approach

Drago Haas , Matthieu Barba , Cláudia M Vincente , Géraldine Le Goff , Jamal Ouazzani
International Symposium on the Biology of Actinomycetes, May 2017, Jeju, South Korea
Communication dans un congrès hal-01655211v1

Generation of a fungal consortium: impact of analytic tools on biodiversity analysis

J Degois , X. Simon , C Bontemps , Pierre Leblond , P Duquenne
European Aerosol Conference EAC 2017, Aug 2017, Zurich, Switzerland
Communication dans un congrès hal-01657801v1

Double strand break repair triggers genome plasticity in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond
Prokagenomics 2017 7th European Conference on Prokaryotic and Fungal Genomics, Sep 2017, Göttingen, Germany
Communication dans un congrès hal-01655261v1

Double strand break repair triggers genome plasticity in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Stephen T Mcgovern , François Lecointe
International Symposium on the Biology of Actinomycetes, May 2017, Jeju, South Korea
Communication dans un congrès hal-01655226v1

Mining genomic islands with Synteruptor, a new strategy for identifying secondary metabolism gene clusters

Drago Haas , Matthieu Barba , Cláudia M Vicente , Amélie Garenaux , Sárka Nezbedová
The 13th International Symposium on the Genetics of Industrial Microorganisms, Oct 2016, Wuhan, China
Communication dans un congrès hal-03042549v1

Impact of nutrient availability on the diversity, function and functioning of the forest soil bacterial communities: insights from the soil succession of the forest experimental site of Montiers.

Stephane Uroz , Marie-Pierre M.-P. Turpault , Océane Nicolitch , Yannick Colin , Marc Buée
Labex ARBRE conference, Oct 2016, Champenoux, France
Communication dans un congrès hal-03339707v1

Bioaerosol biodiversity in waste sorting plant: feasibility and uncertainty measurement

J Degois , F. Clerc , X. Simon , C Bontemps , Pierre Leblond
European Aerosol Conference EAC 2016, Sep 2016, Tours, France
Communication dans un congrès hal-01657790v1

Taxonomic and functional diversity of Streptomyces in a forest soil

Cyril Bontemps , Laurence Hotel , Pierre-Vincent Revol , Mathilde Jeanbille , Stéphane Uroz
Journées Actinomycètes, 2012, Nancy, France
Communication dans un congrès hal-01269133v1

Regulation of Streptococcus thermophilus genomic islands

Nicolas Carraro , Virginie Libante , Morel Catherine , Bernard Decaris , Florence Charron-Bourgoin
FEMS 2011, Jun 2011, Geneva, Switzerland
Communication dans un congrès hal-01909338v1

Etude de la régulation d'ICESt1 et ICESt3, deux éléments intégratifs conjugatifs de Streptococcus thermophilus

Nicolas Carraro , Morel Catherine , Bernard Decaris , Pierre Leblond , Gérard Guédon
17éme colloque du Club des Bactéries Lactiques, Oct 2010, Nancy, France
Communication dans un congrès hal-01909351v1

Etude de la régulation d'ICESt1 et ICESt3, deux éléments intégratifs conjugatifs de Streptococcus thermophilus

Nicolas Carraro , Virginie Libante , Morel Catherine , Decaris Bernard , Florence Charron-Bourgoin
GDR 2157 - Evolution des éléments transposables : des génomes aux populations, Dec 2010, Paris, France
Communication dans un congrès hal-01909335v1
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SIGffRid : Programme de recherche des sites de fixation des facteurs de transcription par approche comparative

Fabrice Touzain , Sophie Schbath , Isabelle Debled-Rennesson , Bertrand Aigle , Pierre Leblond
Journées Ouvertes Biologie Informatique Mathématiques - JOBIM'05, Guy Perrière, Alain Guénoche et Christophe Geourjon, Jul 2005, Lyon, France. pp.417-425
Communication dans un congrès inria-00000191v1
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Data Mining Using Hidden Markov Models (HMM2) to Detect Heterogeneities into Bacteria Genomes

Catherine Eng , Annabelle Thibessard , Sébastien Hergalant , Jean-François Mari , Pierre Leblond
Journées Ouvertes Biologie, Informatique et Mathématiques - JOBIM 2005, JOBIM, Jul 2005, Lyon/France, France
Communication dans un congrès inria-00000142v1
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Fouille de données du génome à l'aide de modèles de Markov cachés

Sébastien Hergalant , Bertrand Aigle , Pierre Leblond , Jean-François Mari
Extraction et Gestion de Connaissances - EGC 2005, Jan 2005, Paris/France, France. pp.141 -- 148
Communication dans un congrès inria-00001213v1
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Classification non supervisée par HMM de sites de fixation de facteurs de transcription chez les bactéries

Sébastien Hergalant , Bertrand Aigle , Bernard Decaris , Jean-François Mari , Pierre Leblond
5èmes Journées Ouvertes : Biologie, Informatique et Mathématiques - JOBIM'04, 2004, Montréal, Canada, 1 p
Communication dans un congrès inria-00107788v1

Identification of Transcription Factor Binding Sites in Streptomyces coelicolor A3(2) by Phylogenetic Comparison

Fabrice Touzain , Patricia Lavigne , Isabelle Debled-Rennesson , Bertrand Aigle , Pierre Leblond
European Conference for Computer Biology - ECCB'2003, 2003, Paris, France
Communication dans un congrès inria-00099608v1

HMM, an Efficient Way to Detect Transcriptional Promoters in Bacterial Genomes?

Sébastien Hergalant , Bertrand Aigle , Bernard Decaris , Jean-François Mari , Pierre Leblond
European Conference on Computational Biology - ECCB'2003, Sep 2003, Paris, France, pp.417--419
Communication dans un congrès inria-00099570v1

Identification of transcription factor binding sites in the genome of Streptomyces coelicolor A3(2)

Patricia Lavigne , Isabelle Debled-Rennesson , Bertrand Aigle , Pierre Leblond , Gregory Kucherov
3ème Journées Post-Génomique de la DOUA 2003 - JPGD'03, 2003, Lyon, France
Communication dans un congrès inria-00099609v1

Intragenomic reiterations detection using hidden Markov models

Sébastien Hergalant , Bertrand Aigle , Bernard Decaris , Pierre Leblond , Jean-François Mari
10th International Conference on Intelligent Systems for Molecular Biology - ISMB 2002, Aug 2002, Edmonton, Canada, 1 p
Communication dans un congrès inria-00100914v1

Fouille de données à l'aide de HMM : Application à la détection de réitérations intragénomiques

Sébastien Hergalant , Bertrand Aigle , Bernard Decaris , Pierre Leblond , Jean-François Mari
Journées Ouvertes Biologie Informatique Mathématiques - JOBIM'02, François Coste - Elisabeth Lebret, 2002, Saint Malo, France, pp.269-273
Communication dans un congrès inria-00100752v1

Identification of a new amplifiable unit of DNA located in the Terminal Inverted repeats of the chromosomal DNA of Streptomyces ambofaciens ATCC23877

Sibel Catakli , Axelle André , Pierre Leblond , Bernard Decaris , Annie Dary
12th International Symposium on the Biology of Actinomycetes (ISBA), Aug 2001, Vancouver, Canada
Communication dans un congrès hal-01161665v1

Identification d’une nouvelle séquence amplifiable localisée aux extrémités du chromosome de Streptomyces ambofaciens ATCC23877

Sibel Catakli , Axelle André , Pierre Leblond , Bernard Decaris , Annie Dary
4ème colloque des 3R : Réplication, Recombinaison et Réparation, Jul 2001, Gif-sur-Yvette, France
Communication dans un congrès hal-01161664v1

Activation of cryptic biosynthetic pathways by bacterial/fungal co-cultures

Matthieu Nicault , Cyril Bontemps , Éric Gelhaye , P. Leblond
Biomolecules: Research & Development, Markets and Acceptability - LUE Impact Biomolecule seminar, Oct 2019, Palma de Mallorca, Spain
Poster de conférence hal-03216601v1
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Massive gene flux in bacterial population fuels adaptation to forest soil ecosystem

Abdoul-Razak Tidjani , Jean-Noël Lorenzi , Olivier Lespinet , Cyril Bontemps , Pierre Leblond
15ème congrès de la Société Française de Microbiologie, Sep 2019, Paris 19ème, France. 2019
Poster de conférence hal-02314235v1
Image document

Interplay between lateral gene transfer and rhizosphere functioning

Caroline Choufa , Abdoul-Razak Tidjani , Claire Veneault-Fourrey , Vos Michiel , Cyril Bontemps
Functional ecology conference 2018, Dec 2018, Nancy, France
Poster de conférence hal-03060574v1

Deciphering and exploiting bacteria-fungi dialogues to identify new bioactive metabolites

Matthieu Nicault , Cyril Bontemps , Éric Gelhaye , Pierre Leblond
12èmes Rencontres de Phytopathologie - Mycologie de la Société Française de Phytopathologie, Jan 2018, Aussois, France
Poster de conférence hal-03216613v1
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Bacteria/fungi Interactions (BFI): a way to awake secondary metabolite gene clusters

Matthieu Nicault , Cyril Bontemps , Éric Gelhaye , Pierre Leblond
Lorraine Université d'Excellence (LUE) Séminaire Impact Biomolécules, May 2018, Nancy, France
Poster de conférence hal-03216622v1

Searching for novel specialized metabolite gene clusters, a new comparative genomics-based approach

Cláudia M Vicente , Matthieu Barba , Drago Haas , Sylvie Lautru , Olivier Lespinet
Directing Biosynthesis V, Mar 2017, Warwick, United Kingdom
Poster de conférence hal-03042555v1

Dynamics and maintenance of ICEs from Streptococcus thermophilus

Nicolas Carraro , Rossi Emmanuel , Antoine Persoons , Morel Catherine , Pierre Leblond
FEMS 2011, Jun 2011, Geneva, Switzerland
Poster de conférence hal-01909343v1

Etude de la régulation du transfert d'éléments intégratifs conjugatifs chez Streptococcus thermophilus

Nicolas Carraro , Morel Catherine , Bernard Decaris , Pierre Leblond , Gérard Guédon
16éme colloque du Club des Bactéries Lactiques, May 2009, Toulouse, France
Poster de conférence hal-01909347v1

Data Mining Using Hidden Markov Models (HMM2) to Detect Heterogeneities into Bacteria Genomes

Catherine Eng , Annabelle Thibessard , Sébastien Hergalant , Jean-François Mari , Pierre Leblond
6. Journées Ouvertes Biologie, Informatique et Mathématiques - JOBIM, Jul 2005, Lyon, France. , 1 p., 2005
Poster de conférence hal-02833554v1

Evidence for a High Heterogeneity Between the Terminal Regions of the Chromosomes of Two Phylogenetically Close Species, Streptomyces ambofaciens and Streptomyces coelicolor by Genome Comparison

Frédéric Choulet , Bertrand Aigle , F. X. Francou , Alexandre Gallois , Céline Fourrier
Streptomyces dissemination meeting, Jul 2003, Guilford, United Kingdom. 2003, Streptomyces dissemination meeting
Poster de conférence hal-01182814v1