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Loss of miR-198 and-206 during primary tumor progression enables metastatic dissemination in human osteosarcoma

Steven Georges , Lidia Rodriguez Calleja , Camille Jacques , Melanie Lavaud , Brice Moukengue , et al.
Oncotarget, 2018, 9, pp.35726 - 35741. ⟨10.18632/oncotarget.26284⟩
Article dans une revue inserm-01982044v1
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Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma

Marion Rabé , Solenne Dumont , Arturo Álvarez-Arenas , Hicham Janati , Juan Belmonte-Beitia , et al.
Cell Death and Disease, 2020, 11 (1), ⟨10.1038/s41419-019-2200-2⟩
Article dans une revue hal-02429194v1
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Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth

Mathilde M Cheray , Romain M Pacaud , Arulraj M Nadaradjane , Lisa M Oliver , François M Vallette , et al.
Theranostics, 2016, 6, pp.1988 - 1999. ⟨10.7150/thno.9150⟩
Article dans une revue inserm-01414173v1

The acquired resistance of mammary cancer cells to CDK4/6 inhibitors drives a DNA methylation reprogramming of genes encoding for BCL2 family members that confers a phenotype of high apopto-sensitivity induced by a BH3-mimetic drug

Jean-Sebastien Frenel , Deborah Voisin , Arulraj Nadaradjane , Gwenola Bougras-Catron , Mario Campone , et al.
San Antonio Breast Cancer Symposium, Dec 2019, San Antonio, United States. pp.P4-04-09-P4-04-09, ⟨10.1158/1538-7445.SABCS19-P4-04-09⟩
Communication dans un congrès inserm-03500281v1
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N6-Adenosine Methylation of miRNA-200b-3p Influences Its Functionality and Is a Theranostic Tool

Joséphine Briand , Aurelien A Serandour , Arulraj Nadaradjane , Gwenola Bougras-Cartron , Dominique Heymann , et al.
Molecular Therapy - Nucleic Acids, 2020, 22, pp.72-83. ⟨10.1016/j.omtn.2020.08.010⟩
Article dans une revue hal-03004313v1
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The TET2 Expression Level Correlates with a Short Relapse Time in Glioblastoma Multiforme

Josephine Briand , Arulraj Nadaradjane , François M. Vallette , Pierre Francois Cartron
Journal of Clinical Epigenetics / J Clin Epigenet, 2018, 04 (02), pp.12. ⟨10.21767/2472-1158.100097⟩
Article dans une revue inserm-01981842v1
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The First alpha Helix of Bax Plays a Necessary Role in Its Ligand-Induced Activation by the BH3-Only Proteins Bid and PUMA

Pierre-Francois Cartron , Tristan Gallenne , Gwenola Bougras , Fabien Gautier , Florence Manero , et al.
Molecular Cell, 2004, 16, pp.807 - 818. ⟨10.1016/j.molcel.2004.10.028⟩
Article dans une revue inserm-02481083v1
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The Activation of Mesenchymal Stem Cells by Glioblastoma Microvesicles Alters Their Exosomal Secretion of miR-100-5p, miR-9-5p and let-7d-5p

Delphine Garnier , Edward Ratcliffe , Joséphine Briand , Pierre-Francois Cartron , Lisa Oliver , et al.
Biomedicines, 2021, 10 (1), pp.112. ⟨10.3390/biomedicines10010112⟩
Article dans une revue inserm-03549681v1
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Cell-free circulating epimarks in cancer monitoring

Manon Duforestel , Josephine Briand , Gwenola Bougras-Cartron , Dominique Heymann , Jean-Sébastien Frenel , et al.
Epigenomics, 2020, 12 (2), pp.145-155. ⟨10.2217/epi-2019-0170⟩
Article dans une revue inserm-02484725v1
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Epigenetic protein complexes: the adequate candidates for the use of a new generation of epidrugs in personalized and precision medicine in cancer

Pierre-Francois Cartron , Mathilde Cheray , Laurent Bretaudeau
Epigenomics, 2019, 12 (2), pp.171-177. ⟨10.2217/epi-2019-0169⟩
Article dans une revue inserm-02484714v1
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TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

Lisenn Lalier , Vincent Mignard , Marie-Pierre Joalland , Didier Lanoé , Pierre-Francois Cartron , et al.
Cell Death and Disease, 2021, 12 (2), pp.182. ⟨10.1038/s41419-021-03471-8⟩
Article dans une revue inserm-03145368v1
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Drug resistance in glioblastoma: are persisters the key to therapy?

Lisa Oliver , Lisenn Lalier , Céline Salaud , Dominique Heymann , Pierre Francois Cartron , et al.
Cancer Drug Resistance, 2020, 3, Online ahead of print. ⟨10.20517/cdr.2020.29⟩
Article dans une revue inserm-02913818v1
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The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

Carmen Brenner , Judith Luciani , Martin Bizet , Matladi Ndlovu , Eleonore Josseaux , et al.
Oncotarget, 2016, [Epub ahead of print]. ⟨10.18632/oncotarget.10624⟩
Article dans une revue inserm-01414047v1

Alterations in DNA methylation/demethylation intermediates predict clinical outcome in chronic lymphocytic leukemia

Cristina Bagacean , Adrian Tempescul , Christelle Le Dantec , Anne Bordron , Audrey Mohr , et al.
Article dans une revue hal-01573947v1

Utilisation d'un composé organométallique en tant que qu'agent de déméthylation de l'ADN

Stéphanie Grandemange , Antonio Monari , Philippe Gros , Pierre-François Cartron
France, N° de brevet: FR3088200. BioSiS. 2020
Brevet hal-02987504v1
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Histone H3 Phosphorylation in GBM: a New Rational to Guide the Use of Kinase Inhibitors in anti-GBM Therapy

Romain Pacaud , Mathilde Cheray , Arulraj Nadaradjane , François M. Vallette , Pierre-François Cartron
Theranostics, 2015, 5 (1), pp.12 - 22. ⟨10.7150/thno.8799⟩
Article dans une revue inserm-01820696v1
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miR-370-3p Is a Therapeutic Tool in Anti-glioblastoma Therapy but Is Not an Intratumoral or Cell-free Circulating Biomarker

Arulraj Nadaradjane , Joséphine Briand , Gwenola Bougras-Cartron , Valentine Disdero , François M. Vallette , et al.
Molecular Therapy - Nucleic Acids, 2018, 13, pp.642-650. ⟨10.1016/j.omtn.2018.09.007⟩
Article dans une revue inserm-01982015v1
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The phosphorylation of Metaxin 1 controls Bak activation during TNFα induced cell death

Elise Petit , Pierre-François Cartron , Lisa Oliver , François M Vallette
Cellular Signalling, 2016, 30, pp.171-178. ⟨10.1016/j.cellsig.2016.11.008⟩
Article dans une revue inserm-01398677v1
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Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death

Irena Moserova , Iva Truxova , Abhishek Garg , Jakub Tomala , Patrizia Agostinis , et al.
OncoImmunology, 2017, 6 (1), pp.e1258505. ⟨10.1080/2162402X.2016.1258505⟩
Article dans une revue inserm-01819520v1
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Kinetics of DNA methylation inheritance by the Dnmt1-including complexes during the cell cycle.

Eric Hervouet , Arulraj Nadaradjane , Marine Gueguen , François Vallette , Pierre-François Cartron
Cell Division, 2012, 7 (1), pp.5. ⟨10.1186/1747-1028-7-5⟩
Article dans une revue inserm-00680687v1

Méthylation/déméthylation de l’ADN et expression du génome

Pierre-François Cartron , Romain Pacaud , Gilles Salbert
Revue Francophone des Laboratoires, 2015, Épigénétique et biologie, 2015 (473), pp.37--48. ⟨10.1016/S1773-035X(15)30158-1⟩
Article dans une revue hal-01165107v1
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Prostaglandins antagonistically control Bax activation during apoptosis

Lisenn Lalier , Pierre-François Cartron , Christophe Olivier , Cedric Logé , Gwenola Bougras , et al.
Cell Death and Differentiation, 2010, ⟨10.1038/cdd.2010.128⟩
Article dans une revue hal-00587969v1
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Control of glioma cell death and differentiation by PKM2–Oct4 interaction

M Morfouace , Lisenn Lalier , L Oliver , M Cheray , Claire Pecqueur , et al.
Cell Death and Disease, 2014, 5, pp.e1036. ⟨10.1038/cddis.2013.561⟩
Article dans une revue inserm-03369748v1
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Disruption of Dnmt1/PCNA/UHRF1 Interactions Promotes Tumorigenesis from Human and Mice Glial Cells

Eric Hervouet , Emilie Debien , Mathilde Cheray , Audrey Geairon , Hélène Rogniaux , et al.
PLoS ONE, 2010, 5 (6), pp.14-14. ⟨10.1371/journal.pone.0011333⟩
Article dans une revue hal-02661168v1
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Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma

Eric Hervouet , Paul Peixoto , Régis Delage-Mourroux , Michaël Boyer-Guittaut , Pierre-François Cartron
Clinical Epigenetics, 2018, 10, pp.17. ⟨10.1186/s13148-018-0450-y⟩
Article dans une revue inserm-01981717v1
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Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner

Manon Duforestel , Arulraj M Nadaradjane , Gwenola Bougras-Cartron , Josephine Briand , Christophe Olivier , et al.
Frontiers in Genetics, 2019, 10, ⟨10.3389/fgene.2019.00885⟩
Article dans une revue inserm-02309615v1
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From 1957 to Nowadays: A Brief History of Epigenetics

Paul Peixoto , Pierre-Francois Cartron , Aurélien A Serandour , Eric Hervouet
International Journal of Molecular Sciences, 2020, 21 (20), pp.7571. ⟨10.3390/ijms21207571⟩
Article dans une revue inserm-03497189v1

Radiotherapy-induced overexpression of exosomal miRNA-378a-3p in cancer cells limits natural killer cells cytotoxicity

Joséphine Briand , Delphine Garnier , Arulraj Nadaradjane , Karen Clément-Colmou , Vincent Potiron , et al.
Epigenomics, 2020, 12 (5), pp.397-408. ⟨10.2217/epi-2019-0193⟩
Article dans une revue inserm-03498832v1
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Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation

Vassilios Myrianthopoulos , Pierre-Francois Cartron , Zita Liutkeviciute , Saulius Klimasauskas , Daumantas Matulis , et al.
European Journal of Medicinal Chemistry, 2016, 114, pp.390 - 396. ⟨10.1016/j.ejmech.2016.02.043⟩
Article dans une revue inserm-01414204v1
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Loss of miR-198 and -206 during primary tumor progression enables metastatic dissemination in human osteosarcoma

Steven Georges , Lidia Rodriguez Calleja , Camille Jacques , Melanie Lavaud , Brice Moukengue , et al.
Oncotarget, 2018, 9 (87), pp.35726 - 35741. ⟨10.18632/oncotarget.26284⟩
Article dans une revue hal-02103169v1