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Regulating the expression of therapeutic transgenes by controlled intake of dietary essential amino acids

 Alain Bruhat , Pierre Fafournoux
ESGCT XXV Anniversary Congress, Oct 2017, Berlin, Germany. 2017, ⟨10.1038/nbt.3582⟩
Poster de conférence hal-02737715v1
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UBE2L3, a Partner of MuRF1/TRIM63, Is Involved in the Degradation of Myofibrillar Actin and Myosin

 Dulce Peris-Moreno , Mélodie Malige , Agnès Claustre , Andrea Armani , Cécile Coudy-Gandilhon , et al.
Cells, 2021, 10 (8), pp.1974. ⟨10.3390/cells10081974⟩
Article dans une revue hal-04183808v1
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Rôle des processus de transport dans l'utilisation hépatique des acides aminés

 P Fafournoux , C Demigné , C Remésy
Reproduction Nutrition Development, 1990, 30 (1), pp.138-138
Article dans une revue hal-00899240v1
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Amino Acid Availability Controls TRB3 Transcription in Liver through the GCN2/eIF2 alpha/ATF4 Pathway

 Valerie Carraro , Anne-Catherine Maurin , Sarah Lambert-Langlais , Julien Averous , Cedric Chaveroux , et al.
PLoS ONE, 2010, 5 (12), ⟨10.1371/journal.pone.0015716⟩
Article dans une revue hal-02660079v1
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The eIF2 alpha/ATF4 pathway is essential for stress-induced autophagy gene expression

 Wafa B'Chir , Anne-Catherine Maurin , Valerie Carraro , Julien Averous , Céline Jousse , et al.
Nucleic Acids Research, 2013, 41 (16), pp.7683 - 7699. ⟨10.1093/nar/gkt563⟩
Article dans une revue hal-01056786v1

Dual role for CHOP in the crosstalk between autophagy and apoptosis to determine cell fate in response to amino acid deprivation

 Wafa B'Chir , Cedric Chaveroux , Valerie Carraro , Julien Averous , Anne-Catherine Maurin , et al.
Cellular Signalling, 2014, 26 (7), pp.1385 - 1391. ⟨10.1016/j.cellsig.2014.03.009⟩
Article dans une revue hal-02638190v1
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Dietary Amino Acid Source Elicits Sex‐Specific Metabolic Response to Diet‐Induced NAFLD in Mice

 Clémence Rives , Céline Marie Pauline Martin , Lauris Evariste , Arnaud Polizzi , Marine Huillet , et al.
Molecular Nutrition and Food Research, 2023, ⟨10.1002/mnfr.202300491⟩
Article dans une revue hal-04287354v1

La kinase GCN2 régule le comportement alimentaire des omnivores afin de maintenir l’homéostasie des acides aminés

 Anne-Catherine Maurin , Céline Jousse , Michelle M. Balage , Julien Averous , Laurent Parry , et al.
Médecine/Sciences, 2005, 21 (10), pp.799-801
Article dans une revue hal-02681321v1

Stabilization of IGFBP-1 mRNA by ethanol in hepatoma cells involves the JNK pathway

 Laurent Magne , Etienne Blanc , Alexandre Marchand , Pierre Fafournoux , Robert Barouki , et al.
Journal of Hepatology, 2007, 47 (5), pp.691-698. ⟨10.1016/j.jhep.2007.05.018⟩
Article dans une revue istex hal-02664643v1
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GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid

 Anne-Catherine Maurin , Laurent Parry , Wafa B’chir , Valérie Carraro , Cécile Coudy-Gandilhon , et al.
Autophagy Reports, 2022, 1 (1), pp.119-142. ⟨10.1080/27694127.2022.2049045⟩
Article dans une revue hal-03749953v1

Leucine : A key amino acid in ageing-associated sarcopeniau?

 Dominique Dardevet , I. Rieu , Pierre Fafournoux , Claire Sornet , Lydie Combaret , et al.
Nutrition Research Reviews, 2003, 16 (1), pp.61-70
Article dans une revue hal-02676366v1

Complex Mechanisms Link Dietary Sulfur Amino Acid Restriction to Health Improvement

 Alain Bruhat , Isabelle Papet , Pierre Fafournoux
Journal of Nutrition, 2021, 151 (4), pp.749-750. ⟨10.1093/jn/nxaa457⟩
Article dans une revue hal-04213087v1

Mécanismes d'action de la leucine au cours de la myogénèse en relation avec la régulation du métabolisme protéique

 Jeremie Talvas , Alain Obled , Pierre Fafournoux , Sylvie Mordier
Journée Scientifique du CNRH D'Auvergne, Apr 2004, Theix, France. 1 p., 2004
Poster de conférence hal-02825341v1

Adaptation of hepatic glutamine metabolism to high-protein diets

 Pierre Fafournoux , Christian Demigné , Christian Remesy
Konferenz der Gesellschaft fuer Biologische Chemie, May 1990, Titisee, Germany
Communication dans un congrès hal-02845609v1

Cellular adaptation to amino acid availability : Mechanisms involved in the regulation of gene expression and protein metabolism

 Sylvie Mordier , Alain Bruhat , Julien Averous , Pierre Fafournoux
Cell and molecular response to stress. Volume 3 : Sensing, signalling and cell adaptation, 3, Elsevier, 2002, 0-444-51147-4
Chapitre d'ouvrage hal-02826696v1

Compréhension de la nutrition au niveau moléculaire

 Pierre Fafournoux
Université d’ÉTÉ de Nutrition 2018, Centre de Recherche en Nutrition Humaine (CRNH). FRA., Sep 2018, Clermont-Ferrand, France
Communication dans un congrès hal-01883231v1

Cellular adaptation to amino acid availability: mechanisms involved in the regulation of gene expression

 Julien Averous , Sarah Langlais , Cedric Chaveroux , Laurent Parry , Valerie Carraro , et al.
Amino acids in human nutrition and health, CABI Publishing, pp.14, 2012, 978-1-84593-798-0
Chapitre d'ouvrage hal-02805890v1

The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores

 Anne-Catherine Maurin , Celine Jousse , Julien Averous , Laurent Parry , Alain Bruhat , et al.
Cell Metabolism, 2005, 1 (4), pp.273-277. ⟨10.1016/j.cmet.2005.03.004⟩
Article dans une revue hal-02454718v1
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GCN2 contributes to mTORC1 inhibition by leucine deprivation through an ATF4 independent mechanism

 Julien Averous , Sarah Lambert-Langlais , Florent Mesclon , Valerie Carraro , Laurent Parry , et al.
Scientific Reports, 2016, 6 (1), pp.27698. ⟨10.1038/srep27698⟩
Article dans une revue hal-01438154v1
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Liver GCN2 controls hepatic FGF21 secretion and modulates whole-body postprandial oxidation profile under a low-protein diet

 Tristan Chalvon Demersay , Joanna Moro , Patrick Even , Catherine C. Chaumontet , Daniel Tomé , et al.
AJP - Endocrinology and Metabolism, 2019, 317 (6), pp.E1015-E1021. ⟨10.1152/ajpendo.00022.2019⟩
Article dans une revue hal-02308960v1
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Perinatal Protein Malnutrition Affects Mitochondrial Function in Adult and Results in a Resistance to High Fat Diet-Induced Obesity

 Céline Jousse , Yuki Muranishi , Laurent Parry , Christophe Montaurier , Patrick Even , et al.
PLoS ONE, 2014, 9 (8), pp.e104896. ⟨10.1371/journal.pone.0104896⟩
Article dans une revue hal-01365546v1

The CCAAT/enhancer-binding protein–ATF response elements-luciferase mouse model, an innovative tool to monitor the integrated stress response pathway in vivo

 Alain Bruhat , Pierre Fafournoux
Current Opinion in Clinical Nutrition and Metabolic Care, 2017, 20 (3), pp.175-180. ⟨10.1097/MCO.0000000000000359⟩
Article dans une revue hal-01595543v1

In vivo imaging of the spatiotemporal activity of the eIF2 -ATF4 signaling pathway: Insights into stress and related disorders

 C. Chaveroux , V. Carraro , L. Canaple , Julien Averous , Anne-Catherine Maurin , et al.
Science Signaling, 2015, 8 (374), pp.rs5-rs5. ⟨10.1126/scisignal.aaa0549⟩
Article dans une revue hal-02459218v1
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Protein restricted diet during gestation and/or lactation in mice affects 15N natural isotopic abundance of organs in the offspring: Effect of diet 15N content and growth

 Karine Bernardo , Céline Jousse , Pierre Fafournoux , Anne Marie Schiphorst , Mathilde Grand , et al.
PLoS ONE, 2018, 13 (10), ⟨10.1371/journal.pone.0205271⟩
Article dans une revue hal-01915683v1

Regulating the expression of therapeutic transgenes by controlled intake of dietary essential amino acids

 Cedric Chaveroux , Alain Bruhat , Valerie Carraro , Céline Jousse , Julien Averous , et al.
Nature Biotechnology, 2016, 34, pp.746-751. ⟨10.1038/nbt.3582⟩
Article dans une revue hal-01594469v1

Recent advances in the understanding of amino acid regulation of gene expression

 Julien Averous , Alain Bruhat , Sylvie Mordier , Pierre Fafournoux
2. Workshop on the Assessment of Adequate Intake of Dietary Amino Acids, Oct 2002, Honolulu, United States
Communication dans un congrès hal-02828538v1
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Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response

 Alain Bruhat , Julien Averous , Valerie Carraro , Can Zhong , Andreas M. Reimold , et al.
Journal of Biological Chemistry, 2002, 277 (50), pp.48107-48114. ⟨10.1074/jbc.M206149200⟩
Article dans une revue hal-02683499v1

Utilisation des substrats glucoformateurs par les hepatocytes isoles de mouton

 Christian Demigné , Pierre Fafournoux , Christian Remesy , C. Yacoub
Reproduction Nutrition Development, 1986, 26 (1B), pp.369-370
Article dans une revue hal-02725377v1

Amino Acids Control Mammalian Gene Transcription: Activating Transcription Factor 2 Is Essential for the Amino Acid Responsiveness of the CHOP Promoter

 Alain Bruhat , Valérie Carraro , Andreas Reimold , Marc M. Ferrara , Pierre Fafournoux
Molecular and Cellular Biology, 2000, 20 (19), pp.7192-7204. ⟨10.1128/mcb.20.19.7192-7204.2000⟩
Article dans une revue hal-02941593v1

Physiological concentration of amino acids regulates insulin-like-growth-factor-binding protein 1 expression

 Céline Jousse , Alain Bruhat , Marc Ferrara , Pierre Fafournoux
Biochemical Journal, 1998, 334 (1), pp.147-153. ⟨10.1042/bj3340147⟩
Article dans une revue hal-02941605v1
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