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The multiple facets of opioid receptor function: implications for addiction

Pierre-Eric Lutz , Brigitte L. Kieffer
Current Opinion in Neurobiology, 2013, 23 (4), pp.473-479. ⟨10.1016/j.conb.2013.02.005⟩
Article dans une revue hal-02437976v1

Epigenetic Regulation of the Kappa Opioid Receptor by Child Abuse

Pierre-Eric Lutz , Jeffrey Gross , Sabine Dhir , Gilles Maussion , Jennie Yang , et al.
Biological Psychiatry, 2018, 84 (10), pp.751-761. ⟨10.1016/j.biopsych.2017.07.012⟩
Article dans une revue hal-02437483v1
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Non-CG methylation and multiple epigenetic layers associate child abuse with immune and small GTPase dysregulation

Pierre-Eric Lutz , Marc-Aurèle Chay , Alain Pacis , Gary Chen , Zahia Aouabed , et al.
Nature Communications, 2021, ⟨10.1101/501239⟩
Article dans une revue hal-03011449v2
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Multiple serotonergic paths to antidepressant efficacy

Pierre-Eric Lutz
Journal of Neurophysiology, 2013, 109 (9), pp.2245-2249. ⟨10.1152/jn.01093.2012⟩
Article dans une revue hal-02437983v1

Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence

Pierre-Eric Lutz , Arnaud Tanti , Alicja Gasecka , Sarah Barnett-Burns , John Kim , et al.
The American Journal of Psychiatry, 2017, 174 (12), pp.1185-1194. ⟨10.1176/appi.ajp.2017.16111286⟩
Article dans une revue hal-02437484v1

Epigenetic regulation of the kappa opioid receptor gene by an insertion–deletion in the promoter region

Pierre-Eric Lutz , Daniel Almeida , Raoul Belzeaux , Ipek Yalcin , Gustavo Turecki
European Neuropsychopharmacology, 2018, 28 (2), pp.334-340. ⟨10.1016/j.euroneuro.2017.12.013⟩
Article dans une revue hal-02359772v1

Focusing on the Opioid System for Addiction Biomarker Discovery

Raoul Belzeaux , Laurence Lalanne , Brigitte Kieffer , Pierre-Eric Lutz
Trends in Molecular Medicine, 2018, 24 (2), pp.206-220. ⟨10.1016/j.molmed.2017.12.004⟩
Article dans une revue hal-04296758v1
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Functional genomic mechanisms of opioid action and opioid use disorder: a systematic review of animal models and human studies

Camille Falconnier , Alba Caparros-Roissard , Charles Decraene , Pierre-Eric Lutz
Molecular Psychiatry, In press, ⟨10.1038/s41380-023-02238-1⟩
Article dans une revue hal-04296738v1
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Hyperactivity of Anterior Cingulate Cortex Areas 24a/24b Drives Chronic Pain-Induced Anxiodepressive-like Consequences

Jim Sellmeijer , Victor Mathis , Sylvain Hugel , Xu-Hui Li , Qian Song , et al.
Journal of Neuroscience, 2018, 38 (12), pp.3102-3115. ⟨10.1523/JNEUROSCI.3195-17.2018⟩
Article dans une revue hal-02437472v1

Neural and molecular correlates of psychological pain during major depression, and its link with suicidal ideas

Fabrice Jollant , Fabricio Perreira , Laura M Fiori , Stéphane Richard-Devantoy , Pierre-Eric Lutz , et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2020, 100, ⟨10.1016/j.pnpbp.2020.109909⟩
Article dans une revue hal-02572929v1
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Childhood Maltreatment and Stress-Related Psychopathology: The Epigenetic Memory Hypothesis

Pierre-Eric Lutz , Daniel Almeida , Laura Fiori , Gustavo Turecki
Current Pharmaceutical Design, 2015, 21 (11), pp.1413-1417. ⟨10.2174/1381612821666150105124928⟩
Article dans une revue hal-02437498v1
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Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides

Arnaud Tanti , Pierre-Eric Lutz , John Kim , Liam O’leary , Jean-François Théroux , et al.
Neuropsychopharmacology, 2019, 44 (12), pp.2099-2111. ⟨10.1038/s41386-019-0471-z⟩
Article dans une revue hal-02437465v1

Transcriptomic and epigenomic biomarkers of antidepressant response

Raoul Belzeaux , Rixing Lin , Chelsey Ju , Marc-Aurele Chay , Laura Fiori , et al.
Journal of Affective Disorders, 2018, 233, pp.36-44. ⟨10.1016/j.jad.2017.08.087⟩
Article dans une revue hal-02437480v1
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Variations in 5-methylcytosine and 5-hydroxymethylcytosine among human brain, blood, and saliva using oxBS and the Infinium MethylationEPIC array

Jeffrey Gross , François Lefebvre , Pierre-Eric Lutz , François Bacot , Daniel Vincent , et al.
Biology Methods and Protocols, 2016, 1 (1), pp.1-8. ⟨10.1093/biomethods/bpw002⟩
Article dans une revue hal-02437515v1

Medications between psychiatric and addictive disorders

Laurence Lalanne , Pierre-Eric Lutz , Benoit Trojak , Jean-Philippe Lang , Brigitte L. Kieffer , et al.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2016, 65, pp.215-223. ⟨10.1016/j.pnpbp.2015.10.009⟩
Article dans une revue hal-02437494v1
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The molecular pathophysiology of mood disorders: From the analysis of single molecular layers to multi-omic integration

Amazigh Mokhtari , Baptiste Porte , Raoul Belzeaux , Bruno Etain , El Cherif Ibrahim , et al.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2022, 116, pp.110520. ⟨10.1016/j.pnpbp.2022.110520⟩
Article dans une revue hal-03568945v1
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Increased functional coupling of the mu opioid receptor in the anterior insula of depressed individuals

Pierre-Eric Lutz , Daniel Almeida , Dominique Filliol , Fabrice Jollant , Brigitte Kieffer , et al.
Neuropsychopharmacology, 2021, ⟨10.1038/s41386-021-00974-y⟩
Article dans une revue hal-03011457v1
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Distinct Mu, Delta, and Kappa Opioid Receptor Mechanisms Underlie Low Sociability and Depressive-Like Behaviors During Heroin Abstinence

Pierre-Eric Lutz , Gulebru Ayranci , Paul Chu-Sin-Chung , Audrey Matifas , Pascale Koebel , et al.
Neuropsychopharmacology, 2014, 39 (11), pp.2694-2705. ⟨10.1038/npp.2014.126⟩
Article dans une revue hal-02437506v1

The Role of Opiates in Social Pain and Suicidal Behavior

Benedicte Nobile , Pierre-Eric Lutz , Emilie Olie , Philippe Courtet
Behavioral Neurobiology of Suicide and Self Harm, 46, pp.197-210, 2020, Current Topics in Behavioral Neurosciences, 978-3-030-57576-2. ⟨10.1007/7854_2020_167⟩
Chapitre d'ouvrage hal-03341966v1

Focusing on the Opioid System for Addiction Biomarker Discovery

Raoul Belzeaux , Laurence Lalanne , Brigitte L. Kieffer , Pierre-Eric Lutz
Trends in Molecular Medicine, 2018, 24 (2), pp.206-220. ⟨10.1016/j.molmed.2017.12.004⟩
Article dans une revue hal-02437476v1
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Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine

Gary Chen , Jeffrey Gross , Pierre-Eric Lutz , Kathryn Vaillancourt , Gilles Maussion , et al.
BMC Genomics, 2017, 18, pp.96. ⟨10.1186/s12864-017-3489-9⟩
Article dans une revue hal-02437490v1
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Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicides

Pierre-Eric Lutz , Yi Zhou , Aurélie Labbe , Naguib Mechawar , Gustavo Turecki
European Neuropsychopharmacology, 2015, 25 (11), pp.2008-2014. ⟨10.1016/j.euroneuro.2015.08.015⟩
Article dans une revue hal-02437496v1
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Sequential and opposing alterations of 5-HT1A receptor function during withdrawal from chronic morphine

Pierre-Eric Lutz , Amynah A. A. Pradhan , Celia Goeldner , Brigitte L. Kieffer
European Neuropsychopharmacology, 2011, 21 (11), pp.835-840. ⟨10.1016/j.euroneuro.2011.02.002⟩
Article dans une revue hal-02437993v1

Neuropathology of suicide: recent findings and future directions

P-E Lutz , N. Mechawar , G Turecki
Molecular Psychiatry, 2017, 22 (10), pp.1395-1412. ⟨10.1038/mp.2017.141⟩
Article dans une revue hal-02437486v1
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The Kappa Opioid Receptor: From Addiction to Depression, and Back

Laurence Lalanne , Gulebru Ayranci , Brigitte L. Kieffer , Pierre-Eric Lutz
Frontiers in Psychiatry, 2014, 5, pp.170. ⟨10.3389/fpsyt.2014.00170⟩
Article dans une revue hal-02437500v1
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Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence

L. Lalanne , G. Ayranci , D. Filliol , C. Gaveriaux-Ruff , K. Befort , et al.
Addiction Biology, 2017, 22 (4), pp.1010-1021. ⟨10.1111/adb.12392⟩
Article dans une revue hal-02437492v1
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Comorbidity of chronic pain and anxiodepressive disorders: Deciphering underlying brain circuits

Léa Becker , Sarah Journée , Pierre-Eric Lutz , Ipek Yalcin
Neuroscience and Biobehavioral Reviews, 2020, 115, pp.131-133. ⟨10.1016/j.neubiorev.2020.05.013⟩
Article dans une revue hal-03010294v1
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Impaired Emotional-Like Behavior and Serotonergic Function During Protracted Abstinence from Chronic Morphine

Celia Goeldner , Pierre-Eric Lutz , Emmanuel Darcq , Thomas Halter , Daniel Clesse , et al.
Biological Psychiatry, 2011, 69 (3), pp.236-244. ⟨10.1016/j.biopsych.2010.08.021⟩
Article dans une revue hal-02437996v1

Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains

Gülebru Ayranci , Katia Befort , Laurence Lalanne , Brigitte Kieffer , Pierre-Eric Lutz
Psychopharmacology, 2015, 232 (11), pp.1957-1971. ⟨10.1007/s00213-014-3826-5⟩
Article dans une revue hal-02437502v1
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Accelerated aging in bipolar disorders: An exploratory study of six epigenetic clocks

Céline Bourdon , Bruno Etain , Luana Spano , Raoul Belzeaux , Marion Leboyer , et al.
Psychiatry Research, 2023, 327, pp.115373. ⟨10.1016/j.psychres.2023.115373⟩
Article dans une revue hal-04181925v2