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Nuclear molecular outflow in the Seyfert galaxy NGC 3227

A. Alonso-Herrero , S. García-Burillo , M. Pereira-Santaella , R. Davies , F. Combes , et al.
Astronomy and Astrophysics - A&A, 2019, 628, pp.A65. ⟨10.1051/0004-6361/201935431⟩
Article dans une revue hal-03127724v1
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Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis

Amandine Cartier-Michaud , Anne-Laure Bailly , Stéphane Betzi , Xiaoli Shi , Jean-Claude Lissitzky , et al.
PLoS Genetics, 2017, 13 (6), ⟨10.1371/journal.pgen.1006803⟩
Article dans une revue hal-01542697v1
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Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer

Laetitia Ganier , Stéphane Betzi , Carine Derviaux , Philippe Roche , Charlotte Dessaux , et al.
ACS Chemical Biology, 2022, 17 (5), pp.1061-1072. ⟨10.1021/acschembio.1c00826⟩
Article dans une revue hal-03817750v1

Molecular dynamics of the FixJ receiver domain: movement of the beta4-alpha4 loop correlates with the in and out flip of Phe101

P. Roche , L. Mouawad , D. Perahia , J.P. Samama , D. Kahn
Protein Science, 2002, 11, pp.2622-2630
Article dans une revue hal-00427236v1

Rhizobium nodulation signals

Jean Dénarié , P. Roche
Molecular signals in plant-microbe communications, CRC Press, 1992
Chapitre d'ouvrage hal-02845578v1
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Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

R. Leblanc , R. Kashyap , K. Barral , A.L. Egea‐jimenez , D. Kovalskyy , et al.
Journal of Extracellular Vesicles, 2020, 10 (2), ⟨10.1002/jev2.12039⟩
Article dans une revue hal-03152593v1
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2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions

Marie-Jeanne Basse , Stéphane Betzi , Xavier Morelli , Philippe Roche
Database - The journal of Biological Databases and Curation, 2016, 2016, pp.6. ⟨10.1093/database/baw007⟩
Article dans une revue hal-01307114v1
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Rational Design of PDZ Domain Inhibitors: Discovery of Small Organic Compounds Targeting PDZ Domains

Laurent Hoffer , Philippe Roche , Xavier Morelli
Jean-Paul Borg. PDZ Mediated Interactions. Methods and Protocols, 2256, Springer US, pp.277-289, 2021, Methods in Molecular Biology, 978-1-0716-1165-4. ⟨10.1007/978-1-0716-1166-1_16⟩
Chapitre d'ouvrage hal-03380205v1

Sulphated lipo-oligosaccharide signals of Rhizobium meliloti elicit root nodule organogenesis in alfalfa

G. Truchet , P. Roche , Patrice Lerouge , Jacques Vasse , Sylvie Camut , et al.
Nature, 1991, 351, 4 p
Article dans une revue hal-02714633v1
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Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors

Jessica Hernandez , Laurent Hoffer , Bruno Coutard , Gilles Quérat , Philippe Roche , et al.
European Journal of Medicinal Chemistry, 2019, 161 (4), pp.323-333. ⟨10.1016/j.ejmech.2018.09.056⟩
Article dans une revue inserm-02378768v1

The genetics of Rhizobium host range control: allelic and non-allelic variation

Frederic Debellé , P. Roche , C. Plazanet , Fabienne Maillet , C. Pujol , et al.
Nitrogen fixation: fundamentals and applications, Kluwer Academic Publishers, 1995
Chapitre d'ouvrage hal-02849646v1

The common nodABC genes of Rhizobium meliloti are host-range determinants

P. Roche , Fabienne Maillet , C. Plazanet , Frederic Debellé , Myriam Ferro , et al.
Proceedings of the National Academy of Sciences of the United States of America, 1996, 93, pp.15305-15310
Article dans une revue hal-02688426v1

The NodA proteins of Rhizobium meliloti and Rhizobium tropici specify the N-acylation of Nod factors by different fatty acids

Frederic Debellé , C. Plazanet , P. Roche , C. Pujol , A. Savagnac , et al.
Molecular Microbiology, 1996, 22 (2), pp.303-314
Article dans une revue hal-02697215v1
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CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation

Kendall Carrasco , Camille Montersino , Carine Derviaux , Magali Saez-Ayala , Laurent Hoffer , et al.
Journal of Medicinal Chemistry, 2022, pp.acs.jmedchem.1c02168. ⟨10.1021/acs.jmedchem.1c02168⟩
Article dans une revue hal-03624836v1
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From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia

Magali Saez-Ayala , Laurent Hoffer , Sébastien Abel , Khaoula Ben Yaala , Benoit Sicard , et al.
Nature Communications, 2023, 14 (1), pp.3079. ⟨10.1038/s41467-023-38668-2⟩
Article dans une revue hal-04237671v1

Molecular basis of symbiotic host specificity in Rhizobium meliloti: nodH and nodPQ genes encode the sulfation of lipo-oligosaccharide signals

P. Roche , Frederic Debellé , Fabienne Maillet , Patrice Lerouge , C. Faucher , et al.
Cell, 1991, 67, pp.1131-1143
Article dans une revue hal-02714087v1

Symbiotic host-specificity of Rhizobium meliloti is determined by a sulphated and acylated glucosamine oligosaccharide signal

Patrice Lerouge , P. Roche , C. Faucher , Fabienne Maillet , G. Truchet , et al.
Nature, 1990, 344, pp.781-784
Article dans une revue hal-02713445v1

Pre-B cell receptor activation : common and distinctive features in human and mouse.

M. Espeli , B. Rossi , S. Mancini , P. Roche , L. Gauthier , et al.
Seminars in Immunology, 2006, 18
Article dans une revue hal-00080908v1
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Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

Laurent Hoffer , Yuliia Voitovich , Brigitt Raux , Kendall Carrasco , Christophe Muller , et al.
Journal of Medicinal Chemistry, 2018, 61 (13), pp.5719-5732. ⟨10.1021/acs.jmedchem.8b00653⟩
Article dans une revue hal-02067797v1

Accelerating small compounds discovery targeting protein-protein interaction

S. Milhas , S. Betzi , P. Roche , M. Cholay , A. Restouin , et al.
FEBS Journal, 2015, 282 (1, SI), pp.134
Article dans une revue hal-01439038v1

In Rhizobium meliloti, the operon associated with the nod box n5 comprises nodL, noeA and noeB, three host-range genes specifically required for the nodulation of particular Medicago species

M. Ardourel , G. Lortet , Fabienne Maillet , P. Roche , G. Truchet , et al.
Molecular Microbiology, 1995, 17 (4), pp.687-699
Article dans une revue hal-02713394v1
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Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein–Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach

Laurent Hoffer , Manon Garcia , Raphael Leblanc , Mikael Feracci , Stéphane Betzi , et al.
Journal of Medicinal Chemistry, 2023, ⟨10.1021/acs.jmedchem.2c01569⟩
Article dans une revue hal-04048842v1

F-18-FDOPA PET/CT Imaging of MAX-Related Pheochromocytoma

David Taieb , Abhishek Jha , Carole Guerin , Ying Pang , Karen T. Adams , et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2018, 103 (4), pp.1574-1582. ⟨10.1210/jc.2017-02324⟩
Article dans une revue hal-02143581v1
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Fragment-based drug design targeting syntenin PDZ2 domain involved in exosomal release and tumour spread

Manon Garcia , Laurent Hoffer , Raphaël Leblanc , Fatiha Benmansour , Mikael Feracci , et al.
European Journal of Medicinal Chemistry, 2021, 223, pp.113601. ⟨10.1016/j.ejmech.2021.113601⟩
Article dans une revue hal-03379016v1