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Multiplexed Droplet Digital PCR Assays for the Simultaneous Screening of Major Genetic Alterations in Tumors of the Central Nervous System
Romain Appay
,
Frederic Fina
,
Doriane Barets
,
Catherine Gallardo
,
Isabelle Nanni-Metellus
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et al.
Article dans une revue
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Targeting the genetic alterations of the PI3K–AKT–mTOR pathway: Its potential use in the treatment of bladder cancers
Nadine Houédé
,
Philippe Pourquier
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inserm-02438837v1
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Genetic polymorphisms of the XPG and XPD nucleotide excision repair genes in sarcoma patients
Valérie Le Morvan
,
Michel Longy
,
Catherine C. Bonaiti-Pellie
,
Binh Bui
,
Nadine Houédé
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et al.
Article dans une revue
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Elongation of oligonucleotide primers forming a triple helix on double-stranded DNA templates by purified DNA polymerases
Patrick Lestienne
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Philippe Pourquier
,
Jacques Bonnet
Article dans une revue
istex
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General overview on DNA repair
Philippe Pourquier
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Jacques Robert
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Early objective response may not be a prognostic factor of survival for patients with metastatic urothelial carcinoma: from a retrospective analysis of a cohort of 113 patients
Guilhem Roubaud
,
Véronique Brouste
,
Phillipe Beuzeboc
,
Aude Fléchon
,
Diego Tosi
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et al.
Article dans une revue
inserm-01264496v1
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Multiplexed-Based Assessment of DNA Damage Response to Chemotherapies Using Cell Imaging Cytometry
Nadia Vezzio-Vié
,
Marie-Alice Kong-Hap
,
Eve Combès
,
Augusto Faria Andrade
,
Maguy del Rio
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et al.
Article dans une revue
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Molecular determinants of response to topoisomerase I inhibitors
Philippe Pourquier
,
Amélie Lansiaux
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inserm-02438828v1
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Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme
Yves Pommier
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Philippe Pourquier
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Yi Fan
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Dirk Strumberg
Article dans une revue
istex
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Polymorphisms in SLCO1B3 and NR1I2 as genetic determinants of hematotoxicity of carboplatin and paclitaxel combination
Litaty Céphanoée Mbatchi
,
Antonin Schmitt
,
Fabienne Thomas
,
Yoann Cazaubon
,
Jacques Robert
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et al.
Article dans une revue
hal-01913499v1
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Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: Its potential use in the treatment of bladder cancers.
Nadine Houédé
,
Philippe Pourquier
Article dans une revue
inserm-01015885v1
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High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor
Hadjer Dellal
,
Abdelhay Boulahtouf
,
Elina Alaterre
,
Alice Cuenant
,
Marina Grimaldi
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et al.
Article dans une revue
hal-03003926v1
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Redox mechanism of levobupivacaine cytostatic effect on human prostate cancer cells
Caroline Jose
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Etienne Hebert-Chatelain
,
Nivea Dias Amoedo
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Emmanuel Roche
,
Emilie Obre
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et al.
Article dans une revue
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New Topoisomerase I mutations are associated with resistance to camptothecin.
Céline Gongora
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Nadia Vezzio-Vie
,
Sandie Tuduri
,
Vincent Denis
,
Annick Causse
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et al.
Article dans une revue
inserm-00602236v1
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Internalization of Foldamer-Based DNA Mimics through a Site-Specific Antibody Conjugate to Target HER2-Positive Cancer Cells
Valentina Corvaglia
,
Imène Ait Mohamed Amar
,
Véronique Garambois
,
Stéphanie Letast
,
Aurélie Garcin
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et al.
Article dans une revue
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Validation of a commercially available indirect ELISA using a nucleocapside recombinant protein for detection of Schmallenberg virus antibodies
Emmanuel Breard
,
Estelle Lara
,
Loic Comtet
,
Cyril Viarouge
,
Virginie Doceul
,
et al.
Article dans une revue
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Structural Basis for Topoisomerase I Inhibition by Nucleoside Analogs
William Gmeiner
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Shuyuan Yu
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Richard Pon
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Philippe Pourquier
,
Yves Pommier
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DNA Protein Cross-Links Produced by NSC 652287, a Novel Thiophene Derivative Active Against Human Renal Cancer Cells
Wilberto Nieves-Neira
,
Maria Rivera
,
Glenda Kohlhagen
,
Miriam Hursey
,
Philippe Pourquier
,
et al.
Article dans une revue
inserm-02438279v1
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Ovarian carcinoma patient derived xenografts reproduce their tumor of origin and preserve an oligoclonal structure
Pierre-Emmanuel Colombo
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Stanislas Du Manoir
,
Beatrice Orsetti
,
Rui Bras-Goncalves
,
Mario Lambros
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et al.
Article dans une revue
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Doxorubicin-induced lipid peroxidation and glutathione peroxidase activity in tumor cell lines selected for resistance to doxorubicin
M. Nabil Benchekroun
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Philippe Pourquier
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Brigitte Schott
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Jacques Robert
Article dans une revue
inserm-02438185v1
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LINE-1 as a therapeutic target for castration-resistant prostate cancer
Nadine Houédé
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Pier Vincenzo Piazza
,
Philippe Pourquier
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inserm-02438852v1
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Effects of modulators of multidrug resistance on the expression of the MDR1 gene in human KB cells in culture
Yan-Ping Hu
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Philippe Pourquier
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François Doignon
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Marc Crouzet
,
Jacques Robert
Article dans une revue
inserm-02438213v1
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Inhibition of Topoisomerase I Cleavage Activity by Thiol-reactive Compounds
Danièle Montaudon
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Komaraiah Palle
,
Laurent Rivory
,
Jacques Robert
,
Celine Douat-Casassus
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et al.
Article dans une revue
inserm-02438667v1
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Induction of Reversible Complexes between Eukaryotic DNA Topoisomerase I and DNA-containing Oxidative Base Damages
Philippe Pourquier
,
Li-Ming Ueng
,
Jolanta Fertala
,
David Wang
,
Hyun-Ju Park
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et al.
Article dans une revue
inserm-02438264v1
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Gemcitabine (2',2'-difluoro-2'-deoxycytidine), an antimetabolite that poisons topoisomerase I.
Philippe Pourquier
,
Christopher Gioffre
,
Glenda Kohlhagen
,
Yoshimasa Urasaki
,
François Goldwasser
,
et al.
Clinical Cancer Research, 2002, 8 (8), pp.2499-504
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Trapping of Mammalian Topoisomerase I and Recombinations Induced by Damaged DNA Containing Nicks or Gaps
Philippe Pourquier
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André Pilon
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Glenda Kohlhagen
,
Abhijit Mazumder
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Aditi Sharma
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et al.
Article dans une revue
inserm-02438225v1
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Transcriptional down-regulation of c-myc expression in an erythroleukemic cell line, K562, and its doxorubicin-resistant variant by two topoisomerase II inhibitors, doxorubicin and amsacrine
Audrey Clary
,
Annick Larrue
,
Philippe Pourquier
,
Jacques Robert
Article dans une revue
inserm-02438227v1
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Molecular determinants of response to topoisomerase II inhibitors
Amélie Lansiaux
,
Philippe Pourquier
Article dans une revue
inserm-02438827v1
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From old alkylating agents to new minor groove binders
Stéphane Puyo
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Danièle Montaudon
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Philippe Pourquier
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Signatures moléculaires dans les cancers de la prostate résistants à la castration : état des lieux
Nadine Houédé
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Philippe Pourquier
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hal-04065732v1
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