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Dysidamide : a cell death inducing drug bypassing Bcl-2 protective activity
F. Manero
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P. Sauleau
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P. Juin
,
F. Vallette
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M.L. Bourguet-Kondracki
IVth European Conference on Marine Natural Products, 2005, Paris, France
Communication dans un congrès
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Random forest of perfect trees: concept, performance, applications and perspectives
Jean-Michel Nguyen
,
Pascal Jézéquel
,
Pierre Gillois
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Luisa Silva
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Faouda Ben Azzouz
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et al.
Article dans une revue
inserm-03546813v1
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TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.
Stéphanie Thébault
,
Morgane Agez
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Xiaoke Chi
,
Johann Stojko
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Vincent Cura
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et al.
Article dans une revue
inserm-01334033v1
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The small organic compound HA14-1 sensitizes human glioblastoma cells to induction of cell death through inhibition of Bcl-2.
F. Manero
,
F. Gautier
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T. Gallenne
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N. Cauquil
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D. Grée
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et al.
Cancer Research, 2006, 66, pp.2757-2764
Article dans une revue
hal-00322859v1
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bc-GenExMiner 4.5: new mining module computes breast cancer differential gene expression analyses
Pascal Jézéquel
,
Wilfried Gouraud
,
Fadoua Ben Azzouz
,
Catherine Guérin-Charbonnel
,
Philippe Juin
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et al.
Article dans une revue
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Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic Systems Against B16-F10 Melanoma Cancer Cells
Duc Duy Vo
,
Isabelle Rouaud
,
Françoise Lohézic-Le Dévéhat
,
Fabien Gautier
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Sophie Barillé-Nion
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et al.
Medicinal Chemistry, 2016
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Survivin contributes to DNA repair by homologous recombination in breast cancer cells
Eloise Véquaud
,
Grégoire Desplanques
,
Pascal Jézéquel
,
Philippe Juin
,
Sophie Barillé-Nion
Article dans une revue
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Corrigendum to “Synthesis of new mixed phenol/heterocyclic derivatives and studies of their activity as inhibitors of Bax/Bcl-xL interaction” [Tetrahedron 70 (2014) 301–311]
Duc Duy Vo
,
Fabien Gautier
,
Sophie Barillé-Nion
,
Philippe Juin
,
Nicolas Levoin
,
et al.
Article dans une revue
hal-01153823v1
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A combination of in-silico and SAR studies to identify binding hot spots of Bcl-xL inhibitors
Nicolas Levoin
,
Duc Duy Vo
,
Fabien Gautier
,
Sophie Barillé-Nion
,
Philippe Juin
,
et al.
Article dans une revue
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Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells
Appala Venkata Ramana Murthy
,
Vennu Narendar
,
Nangunoori Sampath Kumar
,
Pasula Aparna
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Anagani Kanaka Durga Bhavani
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et al.
Article dans une revue
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First Evidence That Oligopyridines, α-Helix Foldamers, Inhibit Mcl-1 and Sensitize Ovarian Carcinoma Cells to Bcl-x L -Targeting Strategies
Céline Gloaguen
,
Anne-Sophie Voisin-Chiret
,
Jana Sopkova-de Oliveira Santos
,
Jade Fogha
,
Fabien Gautier
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et al.
Article dans une revue
hal-02043913v1
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Targeting of BCL-2 Family Members during Anticancer Treatment: A Necessary Compromise between Individual Cell and Ecosystemic Responses?
Sophie C Barillé-Nion
,
Steven Lohard
,
Philippe Juin
Article dans une revue
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HA 14-1, a small molecule inhibitor of Bcl-2, bypasses chemo-resistance in leukaemia cells.
L. Oliver
,
B. Mahé
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R. Grée
,
F.M. Vallette
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P. Juin
Leukemia Research, 2007, 31, pp.859-863
Article dans une revue
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TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax.
G. Bellot
,
P.F. Cartron
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E. Er
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L. Oliver
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P. Juin
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et al.
Cell Death and Differentiation, 2007, 14 ((4)), pp.785-94
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STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment
Steven Lohard
,
Nathalie Bourgeois
,
Laurent A Maillet
,
Fabien P Gautier
,
Aurélie Fétiveau
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et al.
Article dans une revue
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Mitochondria at Center of Exchanges between Cancer Cells and Cancer-Associated Fibroblasts during Tumor Progression
Lisa Nocquet
,
Philippe Juin
,
Frédérique Souazé
Article dans une revue
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E2F1 interacts with BCL‐xL and regulates its subcellular localization dynamics to trigger cell death
Céline Vuillier
,
Steven Lohard
,
Aurélie Fétiveau
,
Jennifer Allègre
,
Cémile Kayaci
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et al.
Article dans une revue
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Synthesis of new mixed phenol/heterocyclic derivatives and studies of their activity as inhibitors of Bax/Bcl-xL interaction
Duc Duy Vo
,
Fabien Gautier
,
Sophie Barillé-Nion
,
Philippe Juin
,
Nicolas Levoin
,
et al.
Article dans une revue
hal-01114411v1
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BCL-XL directly modulates RAS signalling to favour cancer cell stemness.
Sophie de Carné Trécesson
,
Frédérique Souazé
,
Agnes Basseville
,
Anne-Charlotte Bernard
,
Jessie Pécot
,
et al.
Article dans une revue
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Mitotic stress-induced secretome primes cancer cells to apoptosis and maximizes paclitaxel response in breast tumors when combined with BCL-xL-targeting BH3 mimetics
Steven Lohard
,
Philippe Juin
,
Sophie C Barillé-Nion
Article dans une revue
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Decoding and unlocking the BCL‐2 dependency of cancer cells
Philippe Juin
,
Olivier Geneste
,
Fabien Gautier
,
Stéphane Depil
,
Mario Campone
Article dans une revue
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Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance
Jessie Pécot
,
Laurent A Maillet
,
Janic P Le Pen
,
Céline Vuillier
,
Sophie de Carné Trécesson
,
et al.
Article dans une revue
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miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation
Christophe Denoyelle
,
Bernard Lambert
,
M Meryet-Figuière
,
N Vigneron
,
E Brotin
,
et al.
Article dans une revue
hal-02403183v1
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Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode
Siham Hedir
,
Marcella de Giorgi
,
Jade Fogha
,
Martina de Pascale
,
Louis-Bastien Weiswald
,
et al.
Article dans une revue
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The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.
Lazaro E Aira
,
Elodie Villa
,
Pascal Colosetti
,
Parvati Gamas
,
Laurie Signetti
,
et al.
Article dans une revue
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P53 and PTEN expression contribute to the inhibition of EGFR downstream signaling pathway by cetuximab
Sanae Bouali
,
Anne-Sophie Chrétien
,
Carole Ramacci
,
Marie Royer
,
Sophie Marchal
,
et al.
Article dans une revue
hal-00372449v1
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Bax activation by engagement with, then release from, the BH3 binding site of Bcl-xL.
F. Gauthier
,
Y. Guillemain
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P.F. Cartron
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T. Gallenne
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N. Cauquil
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et al.
Molecular and Cellular Biology, 2011, 31 (4), pp.832-44
Article dans une revue
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MCL-1 Modulating compounds for Cancer Treatment
Laurent Poulain
,
Anne-Sophie Voisin-Chiret
,
Jana Sopkova de Oliveira Santos
,
Ronan Bureau
,
Grégory Burzicki
,
et al.
France, Patent n° : WO 2015/132727. 2015
Brevet
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Noxa the BCL-2 Family Member behind the Scenes in Cancer Treatment
Alison Dumont
,
Steven Lohard
,
Laurent A Maillet
,
Philippe Juin
,
Sophie C Barillé-Nion
Journal of Cellular Signaling, 2020, 1 (4), pp.127
Article dans une revue
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Escape from mitotic arrest mediates long term mito-priming of cancer cells by cell autonomous and non-cell autonomous mechanisms
Sophie C Barillé-Nion
,
Steven Lohard
,
Philippe Juin
Gordon Research Conference Cell Death Mediators in Normal and Disease Physiology August 2018 Newry, ME, USA, Aug 2018, Newry, United States
Communication dans un congrès
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