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Sodium background currents in endocrine/neuroendocrine cells: towards unraveling channel identity and contribution in hormone secretion

Nathalie C. Guérineau , Arnaud Monteil , Philippe Lory
Frontiers in Neuroendocrinology, 2021, 63, pp.100947. ⟨10.1016/j.yfrne.2021.100947⟩
Article dans une revue hal-03364483v1

Phosphorylation of the Cav3.2 T-type calcium channel directly regulates its gating properties

Iulia Blesneac , Jean Chemin , Isabelle Bidaud , Sylvaine Huc-Brandt , Franck Vandermoere , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (44), pp.13705-10. ⟨10.1073/pnas.1511740112⟩
Article dans une revue hal-02064367v1
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Activity-dependent regulation of T-type calcium channels by submembrane calcium ions

Magali Cazade , Isabelle Bidaud , Philippe Lory , Jean Chemin
Article dans une revue hal-02440428v1
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The sodium leak channel, NALCN, in health and disease

Maud Cochet-Bissuel , Philippe Lory , Arnaud Monteil
Frontiers in Cellular Neuroscience, 2014, 8, pp.132. ⟨10.3389/fncel.2014.00132⟩
Article dans une revue hal-01950130v1
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A novel phospho-modulatory mechanism contributes to the calcium-dependent regulation of T-type Ca2+ channels

Jean Chemin , Tamara Timic Stamenic , Magali Cazade , Iulia Blesneac , Jodie Llinares , et al.
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-52194-6⟩
Article dans une revue hal-02348120v1
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Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability

Tiphaine Voisin , Emmanuel Bourinet , Philippe Lory
The Journal of Physiology, 2016, 594 (13), pp.3561--74. ⟨10.1113/JP271925⟩
Article dans une revue hal-01940961v1

Mouse hippocampal phosphorylation footprint induced by generalized seizures: Focus on ERK, mTORC1 and Akt/GSK-3 pathways

Giuseppe Gangarossa , Sophie Sakkaki , Philippe Lory , Emmanuel Valjent
Neuroscience, 2015, 311, pp.474-483. ⟨10.1016/j.neuroscience.2015.10.051⟩
Article dans une revue hal-02067117v1
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Modulation of T-type Ca2+ channels by Lavender and Rosemary extracts

Chaymae El Alaoui , Jean Chemin , Taoufiq Fechtali , Philippe Lory
PLoS ONE, 2017, 12 (10), pp.e0186864. ⟨10.1371/journal.pone.0186864⟩
Article dans une revue hal-02059065v1
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A sodium background conductance controls the spiking pattern of mouse adrenal chromaffin cells in situ

Alexandre Milman , Stephanie Venteo , Jean‐louis Bossu , Pierre Fontanaud , Arnaud Monteil , et al.
The Journal of Physiology, 2021, 599 (6), pp.1855-1883. ⟨10.1113/jp281044⟩
Article dans une revue hal-03138604v1
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New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN

Arnaud Monteil , Nathalie C. Guérineau , Antonio Gil-Nagel , Paloma Parra- Diaz , Philippe Lory , et al.
Physiological Reviews, In press, 104 (1), pp.399-472. ⟨10.1152/physrev.00014.2022⟩
Article dans une revue hal-04189096v1

Regulation of T-type calcium channels: Signalling pathways and functional implications

Sylvaine Huc-Brandt , Arnaud Monteil , Isabelle Bidaud , Guillaume Barbara , Jean Chemin , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1793 (6), pp.947-952. ⟨10.1016/j.bbamcr.2008.11.003⟩
Article dans une revue hal-02282056v1

RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2

Julie Salvi , Federica Bertaso , Anne-Laure Mausset-Bonnefont , Alexandra Metz , Céline Lemmers , et al.
Neurobiology of Disease, 2014, 68, pp.47--56. ⟨10.1016/j.nbd.2014.04.005⟩
Article dans une revue hal-01944935v1

T-type voltage gated calcium channels are involved in endothelium-dependent relaxation of mice pulmonary artery

Guillaume Gilbert , Arnaud Courtois , Mathilde Dubois , Laure-Anne Cussac , Thomas Ducret , et al.
Biochemical Pharmacology, 2017, 138, pp.61-72. ⟨10.1016/j.bcp.2017.04.021⟩
Article dans une revue hal-02060440v1

De novo mutations in NALCN cause a syndrome characterized by congenital contractures of the limbs and face, hypotonia, and developmental delay

J. X. Chong , M. J. Mcmillin , K. M. Shively , A. E. Beck , C. T. Marvin , et al.
American Journal of Human Genetics, 2015, 96 (3), pp.462-73. ⟨10.1016/j.ajhg.2015.01.003⟩
Article dans une revue hal-02064371v1

Deciphering pathogenic mechanisms underlying human calcium channelopathies

Philippe Lory , Jean Chemin , Arnaud Monteil , Nathalie C. Guérineau , Sophie Nicole , et al.
Congrès de la Société Française de Physiologie, Jun 2019, Montpellier, France
Communication dans un congrès hal-03020963v1
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New Challenges Resulting From the Loss of Function of Nav1.4 in Neuromuscular Diseases

Sophie Nicole , Philippe Lory
Frontiers in Pharmacology, 2021, 12, pp.751095. ⟨10.3389/fphar.2021.751095⟩
Article dans une revue hal-03406031v1

Design of Carrier Peptide-Oligonucleotide Conjugates with Rapid Membrane Translocation and Nuclear Localization Properties

L. Chaloin , P. Vidal , Philippe Lory , J. Mery , N. Lautredou , et al.
Biochemical and Biophysical Research Communications, 1998, 243 (2), pp.601-608. ⟨10.1006/bbrc.1997.8050⟩
Article dans une revue istex hal-02088286v1
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Structural basis for human Cav3.2 inhibition by selective antagonists

Jian Huang , Xiao Fan , Xueqin Jin , Chen Lyu , Qinmeng Guo , et al.
Cell Research, In press, ⟨10.1038/s41422-024-00959-8⟩
Article dans une revue hal-04549967v1
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The sodium leak channel NALCN regulates cell excitability of pituitary endocrine cells

Hathaichanok Impheng , Céline Lemmers , Malik Bouasse , Christian Legros , Narawut Pakaprot , et al.
FASEB Journal, 2021, 35 (5), pp.e21400. ⟨10.1096/fj.202000841rr⟩
Article dans une revue hal-03188856v1

Characterization of the dominant inheritance mechanism of Episodic Ataxia type 2

Kevin Dorgans , Julie Salvi , Federica Bertaso , Ludivine Bernard , Philippe Lory , et al.
Neurobiology of Disease, 2017, 106, pp.110-123. ⟨10.1016/j.nbd.2017.07.004⟩
Article dans une revue hal-02058986v1
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A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia

Marie Coutelier , Iulia Blesneac , Arnaud Monteil , Marie-Lorraine Monin , Kunie Ando , et al.
American Journal of Human Genetics, 2015, 97 (5), pp.726-737. ⟨10.1016/j.ajhg.2015.09.007⟩
Article dans une revue hal-01223815v1
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Functional expression of CLIFAHDD and IHPRF pathogenic variants of the NALCN channel in neuronal cells reveals both gain- and loss-of-function properties

Malik Bouasse , Hathaichanok Impheng , Zoe Servant , Philippe Lory , Arnaud Monteil
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-48071-x⟩
Article dans une revue hal-02328271v1

α 1H mRNA in single skeletal muscle fibres accounts for T‐type calcium current transient expression during fetal development in mice

Christine Berthier , Arnaud Monteil , Philippe Lory , Caroline Strube
The Journal of Physiology, 2002, 539 (3), pp.681-691. ⟨10.1113/jphysiol.2001.013246⟩
Article dans une revue hal-03093134v1

The involvement of Cav3.2/alpha1H T-type calcium channels in excitability of mouse embryonic primary vestibular neurones

L. Autret , I. Mechaly , F. Scamps , J. Valmier , Philippe Lory , et al.
The Journal of Physiology, 2005, 567, pp.67-78. ⟨10.1113/jphysiol.2005.089342⟩
Article dans une revue hal-00016895v1
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Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons

Neus Bayo-Puxan , Ana Paula Terrasso , Sophie Creyssels , Daniel Simao , Christina Begon-Pescia , et al.
Scientific Reports, 2018, 8, pp.16644. ⟨10.1038/s41598-018-34523-3⟩
Article dans une revue hal-02090806v1

Blockade of T-type calcium channels prevents tonic-clonic seizures in a maximal electroshock seizure model

Sophie Sakkaki , Giuseppe Gangarossa , Benoit Lerat , D. Francon , Luc Forichon , et al.
Neuropharmacology, 2016, 101, pp.320--9. ⟨10.1016/j.neuropharm.2015.09.032⟩
Article dans une revue hal-01936765v1

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone

Magali Cazade , Isabelle Bidaud , P. B. Hansen , Philippe Lory , Jean Chemin
Pflügers Archiv European Journal of Physiology, 2014, 466 (9), pp.1759--68. ⟨10.1007/s00424-013-1411-0⟩
Article dans une revue hal-01942946v1
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CACNA1H Mutations Are Associated With Different Forms of Primary Aldosteronism

Georgios Daniil , Fabio L. Fernandes-Rosa , Jean Chemin , Iulia Blesneac , Jacques Beltrand , et al.
EBioMedicine, 2016, 13, pp.225 - 236. ⟨10.1016/j.ebiom.2016.10.002⟩
Article dans une revue hal-01936768v1

T-type Ca v 3.3 calcium channels produce spontaneous low-threshold action potentials and intracellular calcium oscillations

Marc Chevalier , Philippe Lory , Chantal Mironneau , Nathalie Macrez , Jean-François Quignard
European Journal of Neuroscience, 2006, 23 (9), pp.2321-2329. ⟨10.1111/j.1460-9568.2006.04761.x⟩
Article dans une revue istex hal-02342104v1

De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene

Jean Chemin , Karine Siquier-Pernet , Michael Nicouleau , Giulia Barcia , Ali Ahmad , et al.
Brain - A Journal of Neurology , 2018, 141 (7), pp.1998-2013. ⟨10.1093/brain/awy145⟩
Article dans une revue hal-02017665v1