Researcher identifiers

Number of documents


Dr. Philippe Lesot (Director of research / Senior scientist)

CNRS Director of research (INC, S-12)
(Research PI) "NMR methodologies and anisotropic deuterium NMR applications"

ORCID ID: 0000-0002-5811-7530
Researcher ID: M-3390-2017
Publons ID: Philippe Lesot

RMN en Milieu Orienté, ICMMO, UMR-CNRS 8182, Bât. 410
Université de Paris-Sud / Paris-Saclay 91405 Orsay cedex, Fra


Tél  : ++ 33 (0)1 69 15 47 59 / 70 17 // Fax. : ++ 33 (0)1 69 15 81 05



Dr. Philippe Lesot, born in October 1967, has been Research Director since 2007 at Institut de Chimie Moléculaire et des Materiaux d’Orsay (ICMMO) (France) located at Orsay (University of Paris-Sud/Paris-Saclay).  He is affiliated to the french National Center for Scientific Research (CNRS since 1997.  

He received his Ph.D degree (cum laudae) at University of Paris-Sud (Orsay) in 1995 (supervisor: Prof. J. Courtieu), and then pursued his NMR research activities at University of Southampton (UK) with Prof. J.W. Emsley, awarded by both a grant from the Royal Society of London and the French Foreign Ministry (Lavoisier).  

After holding a temporary assistant professor position at Orsay for one year, he joined the CNRS in 1997.  He was a recipient of the 2001 Bronze Medal from CNRS for young scientists for his pioneering work on the Natural abundance 2D-NMR spectroscopy in chiral liquid crystals.

He has published over 110 publications in international, peer-review journals, 10 bbok chapters inclused two encyclopedian and given approx. 55 invited talks on the analytical and methodological developments in anisotropic NMR in collaboration with numerous (bio)chemists.  His current research interests focus on the natural isotope fractionation of bioproducts by anisotropic NAD NMR and the fight against counterfeiting.



* Scientific board of the INC (CNRS)(2019-2024)  

* Member of S-12 du CoNRS (2008-2016)

* Board of the Academic Council of the COMUE Paris-Saclay (2015-2019)



* Associated Editors of Magnetic Resonance (MR)

* Academic Editors of Concept in Magnetic Resonance A


* Member of editorial borad of "Spectra Analyse" PCI presse, (2014-2018)


* Board of the "Société Française des IsotopeS" (SFIS)

* Member of  the India National Magnetic Resonance Society (NMRS) 


* Expert for the French MESRI (BAP B) 

* Expert for the «DFG» (Deutsche ForschungsGemeinschaft /Allemagne)
* Expert for the «Volskwagen Freigeist fellowships» (
* Expert «European Science Fundation »  (

* Expert «HCERES / AERES»
* Expert «ANR»
* Expert «Agences régionales»   

Chairman and expert of selection committees (ITRF, ITA, Assistant reader,  


- DR2 at CNRS (2007-2019)
- CR1 at CNRS (1997 -2007)
- CR2 at CNRS (1997 -2000)
- Assistant lecturer (Univ Paris-Sud) (1996 -1997)
- Post-Doctoral researcher (University of Southamptopn, UK) (1995-1996)
- Thesis (1992-1995)


* Bronze medal of CNRS (2001)
* Royal Society of London fellowship (1995-1996)
* Lavoisier Grant (1995-1996)


* Scientific book chapters : 9
* Other book chapters : 2
* Communications : 19
* Full articles : 80
* Review/feature articles : 9
* Miscellaneous : 12

* Invited talks:  : 33
* Seminars : 22
* Oral communications : 67
* Posters : 56


* "Thematic GBP NMR network" conference, France, Paris (2020)
* "GBP NMR network" Workshop, France, Orsay (2020)
* "7th Congress of SFIS, France (2019)
* "1st JFPSA", Marocco, Marrakesh, (2017)
* "Thematic GBP NMR network" conference ,France, Paris (2014)
* "GBP NMR network" Workshop, France, Orsay (2014)



Journal of the American Chemical Society   

Journal articles8 documents

  • Philippe Lesot, Olivier Lafon, Herbert Zimmermann, Zeev Luz. Enantiodiscrimination in Deuterium NMR Spectra of Flexible Chiral Molecules with Average Axial Symmetry Dissolved in Chiral Liquid Crystals: The Case of Tridioxyethylenetriphenylene. Journal of the American Chemical Society, American Chemical Society, 2008, 130 (27), pp.8754-8761. ⟨10.1021/ja800957a⟩. ⟨hal-02310973⟩
  • Vincent Baillif, Richard Robins, Isabelle Billault, Philippe Lesot. Assignment of Absolute Configuration of Natural Abundance Deuterium Signals Associated with ( R )- and ( S )-Enantioisotopomers in a Fatty Acid Aligned in a Chiral Liquid Crystal: Enantioselective Synthesis and NMR Analysis. Journal of the American Chemical Society, American Chemical Society, 2006, 128 (34), pp.11180-11187. ⟨10.1021/ja0617892⟩. ⟨hal-02310912⟩
  • Philippe Lesot, Muriel Sarfati, Denis Merlet, Bernard Ancian, James Emsley, et al.. 2D-NMR Strategy Dedicated to the Analysis of Weakly Ordered, Fully Deuterated Enantiomers in Chiral Liquid Crystals. Journal of the American Chemical Society, American Chemical Society, 2003, 125 (25), pp.7689-7695. ⟨10.1021/ja021277x⟩. ⟨hal-02310635⟩
  • Philippe Lesot, Denis Merlet, Muriel Sarfati, Jacques Courtieu, Herbert Zimmermann, et al.. Enantiomeric and Enantiotopic Analysis of Cone-Shaped Compounds with C 3 and C 3 v Symmetry Using NMR Spectroscopy in Chiral Anisotropic Solvents. Journal of the American Chemical Society, American Chemical Society, 2002, 124 (34), pp.10071-10082. ⟨10.1021/ja020269d⟩. ⟨hal-02310599⟩
  • Christie Aroulanda, Denis Merlet, Jacques Courtieu, Philippe Lesot. NMR Experimental Evidence of the Differentiation of Enantiotopic Directions in Cs and C2v Molecules Using Partially Oriented, Chiral Media. Journal of the American Chemical Society, American Chemical Society, 2001, 123 (48), pp.12059-12066. ⟨10.1021/ja011685l⟩. ⟨hal-02309135⟩
  • Denis Merlet, Bernard Ancian, Jacques Courtieu, Philippe Lesot. Two-Dimensional Deuterium NMR Spectroscopy of Chiral Molecules Oriented in a Polypeptide Liquid Crystal: Applications for the Enantiomeric Analysis through Natural Abundance Deuterium NMR. Journal of the American Chemical Society, American Chemical Society, 1999, 121 (22), pp.5249-5258. ⟨10.1021/ja9837699⟩. ⟨hal-02309106⟩
  • D. Merlet, A. Loewenstein, W. Smadja, J. Courtieu, Philippe Lesot. Quantitative Description of the Facial Discrimination of Molecules Containing a Prochiral Group by NMR in a Chiral Liquid Crystal. Journal of the American Chemical Society, American Chemical Society, 1998, 120 (5), pp.963-969. ⟨10.1021/ja9726466⟩. ⟨hal-02309088⟩
  • A. Meddour, P. Berdague, A. Hedli, J. Courtieu, Philippe Lesot. Proton-decoupled carbon-13 NMR spectroscopy in a lyotropic chiral nematic solvent as an analytical tool for the measurement of the enantiomeric excess. Journal of the American Chemical Society, American Chemical Society, 1997, 119 (19), pp.4502-4508. ⟨10.1021/ja964002o⟩. ⟨hal-02324618⟩