Accéder directement au contenu

Philippe Lesot

12
Documents
Identifiants chercheurs

Présentation

### [**CNRS Director of research (DR-1 / INC, S-12)** ](../desktop) [(Research PI) "NMR methodologies and anisotropic deuterium NMR applications"](../desktop) #### *ORCID ID: 0000-0002-5811-7530 Researcher ID: M-3390-2017 Publons ID: Philippe Lesot* #### **RMN en Milieu Orienté, ICMMO, UMR-CNRS 8182, Bât. 410 Université Paris-Saclay 91405 Orsay cedex, Fra**nce **CONTACT &amp; WEBSITES :** Tél : ++ 33 (0)1 69 15 47 59 / 70 17 // Fax. : ++ 33 (0)1 69 15 81 05 E-mail: <philippe.lesot@u-psud.fr> ### [https://www.icmmo.u-psud.fr/fr/perso/philippe-lesot/ ](https://www.icmmo.u-psud.fr/fr/perso/philippe-lesot/)[https://www.researchgate.net/profile/Philippe\_Lesot ](https://www.researchgate.net/profile/Philippe_Lesot)<https://twitter.com/LesotPhilippe> ### [ ](https://twitter.com/LesotPhilippe)https://www.linkedin.com/in/philippe-lesot-47699b51/ **SHORT CV :** Dr. Philippe Lesot, born in October 1967, has been Research Director since 2007 at Institut de Chimie Moléculaire et des Materiaux d’Orsay (ICMMO) (France) located at Orsay (University of Paris-Sud/Paris-Saclay). He is affiliated to the french National Center for Scientific Research (CNRS since 1997. He received his Ph.D degree (cum laudae) at University of Paris-Sud (Orsay) in 1995 (supervisor: Prof. J. Courtieu), and then pursued his NMR research activities at University of Southampton (UK) with Prof. J.W. Emsley, awarded by both a grant from the Royal Society of London and the French Foreign Ministry (Lavoisier). After holding a temporary assistant professor position at Orsay for one year, he joined the CNRS in 1997. He was a recipient of the 2001 Bronze Medal from CNRS for young scientists for his pioneering work on the Natural abundance 2D-NMR spectroscopy in chiral liquid crystals. He has published over 110 publications in international, peer-review journals, 10 bbok chapters inclused two encyclopedian and given approx. 55 invited talks on the analytical and methodological developments in anisotropic NMR in collaboration with numerous (bio)chemists. His current research interests focus on the natural isotope fractionation of bioproducts by anisotropic NAD NMR and the fight against counterfeiting. **SCIENTIFIC MANAGEMENT ACTIVITY :** **\* Scientific board of the INC (CNRS)(2019-2022)** ``` <a href="http://www.cnrs.fr/comitenational/csi/csi_acc.htm">http://www.cnrs.fr/comitenational/csi/csi_acc.htm</a> <br></br><br></br> ``` #### Currently #### \* University office of Paris-Saclay (2020-2023) #### \* Board of the Academic Council of the Univeristy Paris-Saclay (2020-2023) #### \* Member of the CCSU ( 31-32-33) #### Previously : #### \* Board of the Academic Council of the COMUE Paris-Saclay (2015-2019) **\* Member of S-12 du CoNRS (2008-2012 / 2012-2016)** **\* Member of Chemistry Department COMUE Paris-Saclay (2015-2019)** **SCIENTIFIC EDITORIAL ACTIVITY :** **\* Associated Editors of Magnetic Resonance (MR) (2020-)** [https://www.magnetic-resonance-ampere.net/editorial\_board.html](http://www.magnetic-resonance-ampere.net/editorial_board.html) **\* Academic Editors of Concept in Magnetic Resonance A (2018-)** [\* https://www.hindawi.com/journals/cmra/editors/](https://www.hindawi.com/journals/cmra/editors/) ****\*** Member of editorial borad of "Spectra Analyse" PCI presse, (2014-2018)** **\* Board of the "Société Française des IsotopeS**" (SFIS) <https://www.sfis.eu> **\* Member of the India National Magnetic Resonance Society** (NMRS) [http://nmrs.iisc.ernet.in ](http://nmrs.iisc.ernet.in) #### **EXPERTISE COMMITMENT :** \* Expert for the French MESRI (BAP B) \* Expert for the «DFG» (Deutsche ForschungsGemeinschaft /Allemagne) \* Expert for the «Volskwagen Freigeist fellowships» (<http://www.volkswagenstiftung.de>) \* Expert «European Science Fundation » (<http://www..esf.org>) \* Expert «HCERES / AERES» \* Expert «ANR» \* Expert «Agences régionales» \* Chairman and expert of selection committees (ITRF, ITA, Assistant reader, **PREVIOUSLY :** \- DR1 at CNRS (2020-) \- DR2 at CNRS (2007-2019) \- CR1 at CNRS (1997 -2007) \- CR2 at CNRS (1997 -2000) \- Assistant lecturer (Univ Paris-Sud) (1996 -1997) \- Post-Doctoral researcher (University of Southamptopn, UK) (1995-1996) \- Thesis (1992-1995) **DISTINCTIONS :** \* Bronze medal of CNRS (2001) \* Royal Society of London fellowship (1995-1996) \* Lavoisier Grant (1995-1996) **SCIENTIFIC PRODUCTIONS :** \* Scientific book chapters : 8 \* Other book chapters : 2 \* Peer-reviewed articles : 114 \* Miscellaneous (large audience) articles: 13 \* Journal covers : 13 \* Cover profiles : 2 \* Invited talks: : 33 \* Seminars : 22 \* Oral communications : 67 \* Posters : 56 **CONFERENCE/WORKSHOP ORGANISATIONS :** \* "Thematic GBP NMR network" conference, France, Paris (2021) \* "GBP NMR network" Workshop, France, Orsay (2020) \* "7th Congress of SFIS, France (2019) \* "1st JFPSA", Marocco, Marrakesh, (2017) \* "Thematic GBP NMR network" conference ,France, Paris (2014) \* "GBP NMR network" Workshop, France, Orsay (2014)
Philippe Lesot, né en 1967, est directeur de recherche depuis 2007 à l'Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO) (France). Il est affilié au Centre National de la Recherche Scientifique (CNRS). Il a obtenu son doctorat (cum laudae) à l'Université de Paris-Sud (Orsay) en 1995 (superviseur : Prof. J. Courtieu), puis a poursuivi ses activités de recherche à l'Université de Southampton (UK) avec J.W. Emsley, grâce à une bourse de la Royal Society of London et du Ministère français des Affaires étrangères (Lavoisier). Après avoir occupé un poste de professeur assistant temporaire pendant un an, il a rejoint le CNRS en 1997. Il a reçu la Médaille de bronze 2001 du CNRS pour les jeunes scientifiques pour son travail de pionnier sur la RMN du NAD dans la CVX. Il a publié plus de 110 articles dans des revues internationales à comité de lecture, et a donné environ 55 conférences invitées sur les développements analytiques et méthodologiques de la RMN anisotrope en collaboration avec de nombreux (bio)chimistes. Ses intérêts de recherche actuels portent sur le fractionnement des isotopes naturels des bioproduits par RMN anisotrope NAD et la lutte contre la contrefaçon. Traduit avec www.DeepL.com/Translator

Publications

"isabelle-billault"

Analysis of NAD 2D-NMR Spectra of Saturated Fatty Acids in Polypeptide Aligning Media by Experimental and Modeling Approaches

Zeinab Serhan , Andrea Borgogno , Isabelle Billault , Alberta Ferrarini , Philippe Lesot
Chemistry - A European Journal, 2012, 18 (1), pp.117-126. ⟨10.1002/chem.201102775⟩
Article dans une revue hal-02143143v1

Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes

Isabelle Billault , Alicia Le Du , Minale Ouethrani , Zeinab Serhan , Philippe Lesot
Analytical and Bioanalytical Chemistry, 2012, 402 (9), pp.2985-2998. ⟨10.1007/s00216-012-5748-6⟩
Article dans une revue hal-02142700v1

Inside Cover: Analysis of NAD 2D-NMR Spectra of Saturated Fatty Acids in Polypeptide Aligning Media by Experimental and Modeling Approaches (Chem. Eur. J. 1/2012)

Zeinab Serhan , Andrea Borgogno , Isabelle Billault , Alberta Ferrarini , Philippe Lesot
Chemistry - A European Journal, 2012, 18 (1), pp.2-2. ⟨10.1002/chem.201190273⟩
Article dans une revue hal-02316063v1

Analytical contribution of NAD 2D-NMR spectroscopy in polypeptide mesophases to the investigation of triglycerides

Philippe Lesot , Zeinab Serhan , Christie Aroulanda , Isabelle Billault
Magnetic Resonance in Chemistry, 2012, 50, pp.S2-S11. ⟨10.1002/mrc.3855⟩
Article dans une revue hal-02311508v1

Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance H-2 NMR spectroscopy: application to conjugated linolenic methyl esters

Philippe Lesot , Zeinab Serhan , Isabelle Billault
Analytical and Bioanalytical Chemistry, 2011, 399 (3), pp.1187-1200. ⟨10.1007/s00216-010-4394-0⟩
Article dans une revue hal-02143481v1

Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance 2H NMR spectroscopy: application to conjugated linolenic methyl esters

Philippe Lesot , Zeinab Serhan , Isabelle Billault
Analytical and Bioanalytical Chemistry, 2011, 399 (3), pp.1187-1200. ⟨10.1007/s00216-010-4394-0⟩
Article dans une revue hal-02311033v1

Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases

Zeinab Serhan , Laura Martel , Isabelle Billault , Philippe Lesot
Chemical Communications, 2010, 46 (35), pp.6599-6601. ⟨10.1039/c0cc01486a⟩
Article dans une revue hal-02143503v1

Investigation of Fatty Acid Elongation and Desaturation Steps in Fusarium lateritium by Quantitative Two-dimensional Deuterium NMR Spectroscopy in Chiral Oriented Media

Vincent Baillif , Richard J. Robins , Steven Le Feunteun , Philippe Lesot , Isabelle Billault
Journal of Biological Chemistry, 2009, 284 (16), pp.10783-10792. ⟨10.1074/jbc.M807826200⟩
Article dans une revue hal-02143940v1

Combined analysis of C-18 unsaturated fatty acids using natural abundance deuterium 2D NMR spectroscopy in chiral oriented solvents

Philippe Lesot , Vincent Baillif , Isabelle Billault
Analytical Chemistry, 2008, 80 (8), pp.2963-2972. ⟨10.1021/ac702443b⟩
Article dans une revue hal-02143963v1

Assignment of Absolute Configuration of Natural Abundance Deuterium Signals Associated with ( R )- and ( S )-Enantioisotopomers in a Fatty Acid Aligned in a Chiral Liquid Crystal: Enantioselective Synthesis and NMR Analysis

Vincent Baillif , Richard Robins , Isabelle Billault , Philippe Lesot
Journal of the American Chemical Society, 2006, 128 (34), pp.11180-11187. ⟨10.1021/ja0617892⟩
Article dans une revue hal-02310912v1

Exploring the Analytical Potential of NMR Spectroscopy in Chiral Anisotropic Media for the Study of the Natural Abundance Deuterium Distribution in Organic Molecules

Philippe Lesot , Christie Aroulanda , Isabelle Billault
Analytical Chemistry, 2004, 76 (10), pp.2827-2835. ⟨10.1021/ac030385e⟩
Article dans une revue hal-03008466v1

Isotope Ratio Monitoring by NMR. Part 2: New Applications in the Field of Defining Biosynthesis

Richard J. Robins , Gérald Remaud , Isabelle Billault , Philippe Lesot
Ed. G. Webb. Modern Magnetic Resonance, 2nd Edition, Springer International Publishing, pp.1-26, 2017, 978-3-319-28275-6. ⟨10.1007/978-3-319-28275-6_9-1⟩
Chapitre d'ouvrage hal-02321193v1