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Un nouvel axe du mal tumoral ?

Philippe Coulombe , Geneviève Rodier , Sylvain Meloche
Médecine/Sciences, 2009, 25 (8-9), pp.673-675. ⟨10.1051/medsci/2009258-9673⟩
Article dans une revue hal-03101785v1
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Proteomic data on the nuclear interactome of human MCM9

James R.A. Hutchins , Sabine Traver , Philippe Coulombe , Isabelle Peiffer , Magali Kitzmann , et al.
Data in Brief, 2016, 6, pp.410-415. ⟨10.1016/j.dib.2015.11.055⟩
Article dans une revue hal-03101781v1

Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models

Mathilde Soulez , Marc Saba-El-Leil , Benjamin Turgeon , Simon Mathien , Philippe Coulombe , et al.
Molecular and Cellular Biology, 2019, 39 (6), ⟨10.1128/MCB.00527-18⟩
Article dans une revue hal-03101787v1

Programming DNA replication origins and chromosome organization

C. Cayrou , Philippe Coulombe , Marcel Méchali
Chromosome Research, 2010, 18 (1), pp.137-145. ⟨10.1007/s10577-009-9105-3⟩
Article dans une revue hal-00463198v1

Atypical mitogen-activated protein kinases: Structure, regulation and functions

Phillipe Coulombe , Sylvain Meloche
Biochimica et Biophysica Acta - Molecular Cell Research, 2007, 1773 (8), pp.1376-1387. ⟨10.1016/j.bbamcr.2006.11.001⟩
Article dans une revue hal-03101908v1

Expression of angiotensin type II receptor downregulates Cdk4 synthesis and inhibits cell-cycle progression

Bruno Gingras , Geneviève Rodier , Edith Giasson , Philippe Coulombe , Catherine Chassagne , et al.
Oncogene, 2003, 22 (17), pp.2633-2642. ⟨10.1038/sj.onc.1206346⟩
Article dans une revue hal-03101794v1

Rapid Turnover of Extracellular Signal-Regulated Kinase 3 by the Ubiquitin-Proteasome Pathway Defines a Novel Paradigm of Mitogen-Activated Protein Kinase Regulation during Cellular Differentiation

Philippe Coulombe , Geneviève Rodier , Stéphane Pelletier , Johanne Pellerin , Sylvain Meloche
Molecular and Cellular Biology, 2003, 23 (13), pp.4542-4558. ⟨10.1128/MCB.23.13.4542-4558.2003⟩
Article dans une revue hal-03101875v1

Rho Family GTPases Are Required for Activation of Jak/STAT Signaling by G Protein-Coupled Receptors

Stéphane Pelletier , François Duhamel , Philippe Coulombe , Michel Popoff , Sylvain Meloche
Molecular and Cellular Biology, 2003, 23 (4), pp.1316-1333. ⟨10.1128/MCB.23.4.1316-1333.2003⟩
Article dans une revue hal-03101878v1

Purification Process Of Nascent DNA

Marcel Méchali , Christelle Cayrou , Philippe Coulombe , Eric Rivals
United States, Patent n° : US 61/238 315 - WO2011023827 (A1). 2010
Brevet hal-03102676v1

N-Terminal Ubiquitination of Extracellular Signal-Regulated Kinase 3 and p21 Directs Their Degradation by the Proteasome

Marcel Méchali , Kazumasa Yoshida , Philippe Pasero , Philippe Coulombe , Geneviève Rodier , et al.
Molecular and Cellular Biology, 2004, 24 (14), pp.6140-6150. ⟨10.1128/MCB.24.14.6140-6150.2004⟩
Article dans une revue hal-03101868v1
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The ORC ubiquitin ligase OBI1 promotes DNA replication origin firing

Philippe Coulombe , Joelle Nassar , Isabelle Peiffer , Slavica Stanojcic , Yvon Sterkers , et al.
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-10321-x⟩
Article dans une revue hal-02408667v1

Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APCCdh1 in G1 phase

Geneviève Rodier , Philippe Coulombe , Pierre-Luc Tanguay , Christel Boutonnet , Sylvain Meloche
EMBO Journal, 2008, 27 (4), pp.679-691. ⟨10.1038/emboj.2008.6⟩
Article dans une revue hal-03101860v1

Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5

Paul Déléris , Justine Rousseau , Philippe Coulombe , Geneviève Rodier , Pierre-Luc Tanguay , et al.
Journal of Cellular Physiology, 2008, 217 (3), pp.778-788. ⟨10.1002/jcp.21560⟩
Article dans une revue istex hal-03101848v1
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p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2

Geneviève Rodier , Constantin Makris , Philippe Coulombe , Anthony Scime , Keiko Nakayama , et al.
Journal of Cell Biology, 2005, 168 (1), pp.55-66. ⟨10.1083/jcb.200404146⟩
Article dans une revue hal-03101824v1

New insights into replication origin characteristics in metazoans

C Cayrou , Philippe Coulombe , Aurore Puy , Stéphanie Rialle , Noam Kaplan , et al.
Cell Cycle, 2012, 11 (4), pp.658-67. ⟨10.4161/cc.11.4.19097⟩
Article dans une revue hal-00668750v1

A spontaneous Cdt1 mutation in 129 mouse strains reveals a regulatory domain restraining replication licensing

P. Coulombe , Grégoire David , N. Tsanov , M. Mechali
Nature Communications, 2013, 4, pp.2065. ⟨10.1038/ncomms3065⟩
Article dans une revue hal-00852756v1
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Differential Regulation of P27Kip1 Expression by Mitogenic and Hypertrophic Factors

Marc Servant , Philippe Coulombe , Benjamin Turgeon , Sylvain Meloche
Journal of Cell Biology, 2000, 148 (3), pp.543-556. ⟨10.1083/jcb.148.3.543⟩
Article dans une revue hal-03101882v1
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Genome-Scale Analysis of Metazoan Replication Origins Reveals their Organization in Specific but Flexible Sites Defined by Conserved Features

Christelle Cayrou , Philippe Coulombe , Alice Vigneron , Slavica Stanojcic , Olivier Ganier , et al.
Genome Research, 2011, 21 (9), pp.1438-1449. ⟨10.1101/gr.121830.111⟩
Article dans une revue lirmm-00631491v1
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The chromatin environment shapes DNA replication origin organization and defines origin classes

Christelle Cayrou , Benoit Ballester , Isabelle Peiffer , Romain Fenouil , Philippe Coulombe , et al.
Genome Research, 2015, 25 (12), pp.1873-1885. ⟨10.1101/gr.192799.115⟩
Article dans une revue hal-03101863v1

Dual-tag prokaryotic vectors for enhanced expression of full-length recombinant proteins

Philippe Coulombe , Sylvain Meloche
Analytical Biochemistry, 2002, 310 (2), pp.219-222. ⟨10.1016/S0003-2697(02)00319-6⟩
Article dans une revue istex hal-03101796v1
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Involvement of G-quadruplex regions in mammalian replication origin activity

Paulina Prorok , Marie Artufel , Antoine Aze , Philippe Coulombe , Isabelle Peiffer , et al.
Nature Communications, 2019, 10 (1), pp.3274. ⟨10.1038/s41467-019-11104-0⟩
Article dans une revue hal-03101805v1
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MCM9 Is Required for Mammalian DNA Mismatch Repair

Sabine Traver , Philippe Coulombe , Isabelle Peiffer , James R. A. Hutchins , Magali Kitzmann , et al.
Molecular Cell, 2015, 59 (5), pp.831-839. ⟨10.1016/j.molcel.2015.07.010⟩
Article dans une revue hal-02361154v1

Genome-scale identification of active DNA replication origins

C Cayrou , Damien Gregoire , Philippe Coulombe , Etienne Danis , Marcel Méchali
Methods, 2012, 57 (2), pp.158-164. ⟨10.1016/j.ymeth.2012.06.015⟩
Article dans une revue istex hal-00733286v1

Involvement of the IκB Kinase (IKK)-Related Kinases Tank-Binding Kinase 1/IKKi and Cullin-Based Ubiquitin Ligases in IFN Regulatory Factor-3 Degradation

Annie Bibeau-Poirier , Simon-Pierre Gravel , Jean-François Clément , Sébastien Rolland , Geneviève Rodier , et al.
Journal of Immunology, 2006, 177 (8), pp.5059-5067. ⟨10.4049/jimmunol.177.8.5059⟩
Article dans une revue hal-03101855v1

Phosphorylation of Ser72 does not regulate the ubiquitin ligase activity and subcellular localization of Skp2

Christel Boutonnet , Pierre-Luc Tanguay , Catherine Julien , Geneviève Rodier , Philippe Coulombe , et al.
Cell Cycle, 2014, 9 (5), pp.975-979. ⟨10.4161/cc.9.5.10915⟩
Article dans une revue hal-03101801v1
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Nuclear Export of ERK3 by a CRM1-dependent Mechanism Regulates Its Inhibitory Action on Cell Cycle Progression

Catherine Julien , Philippe Coulombe , Sylvain Meloche
Journal of Biological Chemistry, 2003, 278 (43), pp.42615-42624. ⟨10.1074/jbc.M302724200⟩
Article dans une revue hal-03101852v1
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PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damage

Nikolay Tsanov , Chames Kermi , P. Coulombe , Siem van Der Laan , Dana Hodroj , et al.
Nucleic Acids Research, 2014, 42 (6), pp.3692-3706. ⟨10.1093/nar/gkt1400⟩
Article dans une revue hal-00975187v1

DNA replication origin activation in space and time

M Fragkos , O. Ganier , P. Coulombe , M. Mechali
Nature Reviews Molecular Cell Biology, 2015, 16 (6), pp.360-374. ⟨10.1038/nrm4002⟩
Article dans une revue hal-01159618v1

Purification Process Of Nascent DNA

Marcel Méchali , Philippe Coulombe , C Cayrou , Eric Rivals
United States, Patent n° : US 61/238 315 - WO2011023827 (A1). 2011, pp.N/A
Brevet lirmm-00832553v1

Genetic and epigenetic determinants of DNA replication origins, position and activation

M. Mechali , K. Yoshida , P. Coulombe , P. Pasero
Current Opinion in Genetics and Development, 2013, 23 (2), pp.124-131. ⟨10.1016/j.gde.2013.02.010⟩
Article dans une revue istex hal-00824364v1