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The Viral Class II Membrane Fusion Machinery: Divergent Evolution from an Ancestral Heterodimer

Pablo Guardado-Calvo , Félix Rey
Viruses, 2021, 13 (12), pp.2368. ⟨10.3390/v13122368⟩
Article dans une revue pasteur-03902512v1
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Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc

Pablo Guardado-Calvo , Eduardo A. Bignon , Eva Stettner , Scott Allen Jeffers , Jimena Pérez-Vargas , et al.
PLoS Pathogens, 2016, 12 (10), pp.e1005813. ⟨10.1371/journal.ppat.1005813⟩
Article dans une revue pasteur-01390226v1
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A Search for Tick-Associated, Bronnoya-like Virus Spillover into Sheep

Bianca Elena Bratuleanu , Cristian Raileanu , Delphine Chrétien , Pablo Guardado-Calvo , Thomas Bigot , et al.
Microorganisms, 2023, 11 (1), pp.209. ⟨10.3390/microorganisms11010209⟩
Article dans une revue pasteur-04103246v1

Diversity of Viruses in Ixodes ricinus in Europe including Novel and Potential Arboviruses

Bianca Elena Bratuleanu , Cristian Răileanu , Amal Bennouna , Delphine Chretien , Thomas Bigot , et al.
Transboundary and emerging diseases, 2023, 2023, pp.1-14. ⟨10.1155/2023/6661723⟩
Article dans une revue hal-04314227v1
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Recognition determinants of broadly neutralizing human antibodies against dengue viruses.

Alexander Rouvinski , Pablo Guardado-Calvo , Giovanna Barba-Spaeth , Stéphane Duquerroy , Marie-Christine Vaney , et al.
Nature, 2015, 520 (7545), pp.109-113. ⟨10.1038/nature14130⟩
Article dans une revue hal-01148962v1

A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion

Pablo Guardado-Calvo , K. Atkovska , S. A. Jeffers , N. Grau , Marija Backovic , et al.
Science, 2017, 358 (6363), pp.663 - 667. ⟨10.1126/science.aal2712⟩
Article dans une revue pasteur-01632899v1
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The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses

Arvind Sharma , Xiaokang Zhang , Wanwisa Dejnirattisai , Xinghong Dai , Danyang Gong , et al.
Cell, 2021, 184 (25), pp.6052-6066.e18. ⟨10.1016/j.cell.2021.11.010⟩
Article dans une revue pasteur-03524447v1
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The surface glycoproteins of hantaviruses

Pablo Guardado-Calvo , Félix Rey
Current Opinion in Virology, 2021, 50, pp.87-94. ⟨10.1016/j.coviro.2021.07.009⟩
Article dans une revue hal-03329508v1
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Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein

Jan Hellert , Andrea Aebischer , Ahmed Haouz , Pablo Guardado-Calvo , Sven Reiche , et al.
Cell Reports, 2023, 42 (3), pp.112142. ⟨10.1016/j.celrep.2023.112142⟩
Article dans une revue pasteur-04123190v1

Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.

Annalisa Meola , Célia Deville , Scott A Jeffers , Pablo Guardado-Calvo , Ieva Vasiliauskaite , et al.
Journal of Structural Biology, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩
Article dans une revue hal-01077147v1

The Envelope Proteins of the Bunyavirales

Pablo Guardado-Calvo , Félix Rey
Advances in Virus Research, 98, pp.83-118, 2017, 978-0-12-812596-0. ⟨10.1016/bs.aivir.2017.02.002⟩
Chapitre d'ouvrage pasteur-03207993v1
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Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope

Alexander Rouvinski , Wanwisa Dejnirattisai , Pablo Guardado-Calvo , Marie-Christine Vaney , Arvind Sharma , et al.
Nature Communications, 2017, 8, pp.15411. ⟨10.1038/ncomms15411⟩
Article dans une revue pasteur-01540166v1
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Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling

Taylor P. Light , Delphine Brun , Pablo Guardado-Calvo , Riccardo Pederzoli , Ahmed Haouz , et al.
2021
Pré-publication, Document de travail pasteur-03259671v1

Protocadherin-1 is essential for cell entry by New World hantaviruses

Rohit Jangra , Andrew Herbert , Rong Li , Lucas Jae , Lara Kleinfelter , et al.
Nature, 2018, 563 (7732), pp.559-563. ⟨10.1038/s41586-018-0702-1⟩
Article dans une revue pasteur-03207979v1
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The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism

Alexandra Serris , Robert Stass , Eduardo Bignon , Nicolás Muena , Jean-Claude Manuguerra , et al.
Cell, 2020, 183 (2), pp.442-456.e16. ⟨10.1016/j.cell.2020.08.023⟩
Article dans une revue pasteur-03207940v1
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Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection

Megan M Slough , Rong Li , Andrew S Herbert , Gorka Lasso , Ana I Kuehne , et al.
Nature Communications, 2023, 14 (1), pp.4454. ⟨10.1038/s41467-023-40126-y⟩
Article dans une revue pasteur-04364167v1

Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses

Eva Mittler , Anna Wec , Janne Tynell , Pablo Guardado-Calvo , Julia Wigren-Byström , et al.
Science Translational Medicine, 2022, 14 (636), ⟨10.1126/scitranslmed.abl5399⟩
Article dans une revue pasteur-03902510v1
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Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

Eduardo Bignon , Amelina Albornoz , Pablo Guardado-Calvo , Félix Rey , Nicole Tischler
eLife, 2019, 8, pp.e46028. ⟨10.7554/eLife.46028⟩
Article dans une revue pasteur-03207972v1
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Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling

Taylor P. Light , Delphine Brun , Pablo Guardado-Calvo , Riccardo Pederzoli , Ahmed Haouz , et al.
PLoS Biology, 2021, 19 (9), pp.e3001392. ⟨10.1371/journal.pbio.3001392⟩
Article dans une revue pasteur-03388352v1
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Editorial: Influence of Protein-Protein Interactions (PPIs) on the Outcome of Viral Infections

Rohit Jangra , Mercè Llabrés , Pablo Guardado-Calvo , Eva Mittler , Gorka Lasso
Frontiers in Microbiology, 2022, 13, pp.943379. ⟨10.3389/fmicb.2022.943379⟩
Article dans une revue pasteur-03902520v1
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Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2

Cyril Planchais , Ignacio Fernández , Timothée Bruel , Guilherme Dias de Melo , Matthieu Prot , et al.
Journal of Experimental Medicine, 2022, 219 (7), pp.e20220638. ⟨10.1084/jem.20220638⟩
Article dans une revue hal-03697587v1
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Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope

Karim Dorgham , Nicolas Pietrancosta , Amel Affoune , Olivier Lucar , Tahar Bouceba , et al.
Journal of Immunology Research, 2019, 2019, pp.9804584. ⟨10.1155/2019/9804584⟩
Article dans une revue hal-02162037v1
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Generation of plasma cells and CD27 - IgD - B cells during hantavirus infection is associated with distinct pathological findings

Priscilla F Kerkman , Andy Dernstedt , Lalitha Tadala , Eva Mittler , Mirjam Dannborg , et al.
Clinical & Translational Immunology, 2021, 10, pp.e1313. ⟨10.1002/cti2.1313⟩
Article dans une revue pasteur-03388390v1

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody

Eva Mittler , Alexandra Serris , Emma Esterman , Catalina Florez , Laura Polanco , et al.
Science Translational Medicine, 2023, 15 (700), pp.eadg1855. ⟨10.1126/scitranslmed.adg1855⟩
Article dans une revue pasteur-04129288v1
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Neutralization Determinants on Poxviruses

Vernuccio Riccardo , Guardado-Calvo Pablo
Viruses, 2023, 15 (12), pp.2396. ⟨10.3390/v15122396⟩
Article dans une revue pasteur-04364160v1
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Multimeric single-domain antibody complexes protect against bunyavirus infections

Paul Wichgers Schreur , Sandra van de Water , Michiel Harmsen , Erick Bermúdez-Méndez , Dubravka Drabek , et al.
eLife, 2020, 9, pp.e52716. ⟨10.7554/eLife.52716⟩
Article dans une revue pasteur-03207969v1
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Orthobunyavirus spike architecture and recognition by neutralizing antibodies

Jan Hellert , Andrea Aebischer , Kerstin Wernike , Ahmed Haouz , Emiliana Brocchi , et al.
Nature Communications, 2019, 10 (1), pp.879. ⟨10.1038/s41467-019-08832-8⟩
Article dans une revue pasteur-03207977v1
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Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

Taylor Engdahl , Elad Binshtein , Rebecca Brocato , Natalia Kuzmina , Lucia Principe , et al.
eLife, 2023, 12, ⟨10.7554/eLife.81743⟩
Article dans une revue pasteur-04123202v1
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Structure-function dissection of the Pseudorabies virus glycoprotein B fusion loops

Melina Vallbracht , Delphine Brun , Matteo Tassinari , Marie-Christine Vaney , Gerard Pehau-Arnaudet , et al.
Journal of Virology, 2017, 92 (1), pp.e01203-17. ⟨10.1128/JVI.01203-17⟩
Article dans une revue pasteur-01632896v1
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Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies

Akaash K Mishra , Jan Hellert , Natalia Freitas , Pablo Guardado-Calvo , Ahmed Haouz , et al.
iScience, 2022, 375 (6576), pp.104-109. ⟨10.1126/science.abl6502⟩
Article dans une revue pasteur-03525373v1