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Protein Phosphorylation in Cancer: Unraveling the Signaling Pathways

Peter Coopman
Biomolecules, 2022, 12 (8), pp.1036. ⟨10.3390/biom12081036⟩
Article dans une revue hal-04285632v1
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The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex

Toufic Kassouf , Romain Maxime Larive , Anne Morel , Serge Urbach , Nadir Bettache , et al.
Cancers, 2019, 11 (12), pp.1974. ⟨10.3390/cancers11121974⟩
Article dans une revue hal-02401110v1
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Dual Role of the PTPN13 Tyrosine Phosphatase in Cancer

Soha Mcheik , Leticia Aptecar , Peter Coopman , Véronique D’hondt , Gilles Gf Freiss
Biomolecules, 2020, 10, ⟨10.3390/biom10121659⟩
Article dans une revue hal-03116270v1
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PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness

Mohamed Hamyeh , Florence F. Bernex , Romain M Larive , Aurélien Naldi , S Urbach , et al.
Theranostics, In press, 10 (3), pp.1016-1032. ⟨10.7150/thno.38537⟩
Article dans une revue hal-02401068v1
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Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells

Aurélien Naldi , Romain Larive , Urszula Czerwinska , Serge Urbach , Philippe Montcourrier , et al.
PLoS Computational Biology, 2017, 13 (3), pp.e1005432. ⟨10.1371/journal.pcbi.1005432⟩
Article dans une revue hal-02073659v1
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Protein Phosphorylation in Cancer: Unraveling the Signaling Pathways

Peter Coopman
Biomolecules, 2022, 12 (8), pp.1036. ⟨10.3390/biom12081036⟩
Article dans une revue hal-03800648v1
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High PTPN13 expression in high grade serous ovarian carcinoma is associated with a better patient outcome

Véronique D’hondt , Magalie Lacroix-Triki , Marta Jarlier , Florence Boissière-Michot , Carole Puech , et al.
Oncotarget, 2017, 8 (56), ⟨10.18632/oncotarget.21175⟩
Article dans une revue hal-02313763v1
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Centrosomal targeting of Syk kinase is controlled by its catalytic activity and depends on microtubules and the dynein motor.

Guillaume Fargier , Cyril Favard , Andrea Parmeggiani , Alain Sahuquet , Fabrice Mérezègue , et al.
FASEB Journal, 2013, 27 (1), pp.109-22. ⟨10.1096/fj.11-202465⟩
Article dans une revue inserm-00749959v1
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Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions

Marion Buffard , Aurélien Naldi , Gilles Gf Freiss , Marcel Deckert , Ovidiu Radulescu , et al.
Biomolecules, 2021, 11 (2), pp.308. ⟨10.3390/biom11020308⟩
Article dans une revue hal-03160560v1
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Catalytically inactive human cathepsin D triggers fibroblast invasive growth.

Valérie Laurent-Matha , Sharon Maruani-Herrmann , Christine Prébois , Mélanie Beaujouin , Murielle Glondu , et al.
Journal of Cell Biology, 2005, 168 (3), pp.489-99. ⟨10.1083/jcb.200403078⟩
Article dans une revue inserm-00153783v1
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SYK Inhibition Potentiates the Effect of Chemotherapeutic Drugs on Neuroblastoma Cells in Vitro

Conny Tümmler , Gianina Dumitriu , Malin Wickström , Peter Coopman , Andrey Valkov , et al.
Cancers, 2019, 11 (2), pp.202. ⟨10.3390/cancers11020202⟩
Article dans une revue hal-02371232v1

Cell membrane extensions, generated by mechanical constraint, are associated with a sustained lipid raft patching and an increased cell signaling.

Romain M Larive , Laurent Baisamy , Serge Urbach , Peter Coopman , Nadir Bettache
Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (3), pp.389-400. ⟨10.1016/j.bbamem.2009.11.016⟩
Article dans une revue hal-00492403v1

An integrated cell line-based discovery strategy identified follistatin and kallikrein 6 as serum biomarker candidates of breast carcinoma

Alain Mangé , Lampros Dimitrakopoulos , Antoninus Soosaipillai , Peter Coopman , Eleftherios Diamandis , et al.
Journal of Proteomics, 2016, 142, pp.114 - 121. ⟨10.1016/j.jprot.2016.04.050⟩
Article dans une revue hal-01868329v1
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FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer

Alain Mangé , Etienne Coyaud , Caroline Desmetz , Estelle Laurent , Benoit Béganton , et al.
Theranostics, 2019, 9 (23), pp.7003-7015. ⟨10.7150/thno.35561⟩
Article dans une revue hal-02359160v1

Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion.

R. M. Larive , Serge Urbach , Joël Poncet , Patrick Jouin , G. Mascré , et al.
Oncogene, 2009, 28 (24), pp.2337-47. ⟨10.1038/onc.2009.99⟩
Article dans une revue hal-00400163v1

Characterization of centrosomal localization and dynamics of Cdc25C phosphatase in mitosis.

Jérôme Bonnet , Peter Coopman , May C Morris
Cell Cycle, 2008, 7 (13), pp.1991-8. ⟨10.4161/cc.7.13.6095⟩
Article dans une revue hal-00350866v1
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PTPN13 Participates in the Regulation of Epithelial–Mesenchymal Transition and Platinum Sensitivity in High-Grade Serous Ovarian Carcinoma Cells

Leticia Aptecar , Carole Puech , Evelyne Lopez-Crapez , Marion Peter , Peter Coopman , et al.
International Journal of Molecular Sciences, 2023, 24 (20), pp.15413. ⟨10.3390/ijms242015413⟩
Article dans une revue hal-04285044v1

Abstract 1978: The tyrosine kinase Syk plays a role in the maintenance of intercellular adhesive junctions in human breast cancer cells

Toufic Kassouf , Philippe Montcourrier , Romain Larive , Nadir Bettache , Anne Morel , et al.
Cancer Research, 2014, 74 (19S), pp.1978-1978. ⟨10.1158/1538-7445.AM2014-1978⟩
Article dans une revue hal-03575279v1
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Network Reconstruction and Significant Pathway Extraction Using Phosphoproteomic Data from Cancer Cells

Marion Buffard , Aurélien Naldi , Ovidiu Radulescu , Peter Coopman , Romain Larive , et al.
Proteomics, 2019, 19 (21-22), pp.1800450. ⟨10.1002/pmic.201800450⟩
Article dans une revue hal-03049205v1

Phosphorylated Tyr142 β-catenin localizes to centrosomes and is regulated by Syk

Deepshikha Bhardwaj , Mireia Náger , Anna Visa , Marta Sallán , Peter Coopman , et al.
Journal of Cellular Biochemistry, 2018, 119 (4), pp.3632-3640. ⟨10.1002/jcb.26571⟩
Article dans une revue hal-02281444v1
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Detection of known and novel ALK fusion transcripts in lung cancer patients using next-generation sequencing approaches

Julie A. Vendrell , Sylvie Taviaux , Beno\ⁱt Béganton , Sylvain Godreuil , Patricia Audran , et al.
Scientific Reports, 2017, 7 (1), pp.12510. ⟨10.1038/s41598-017-12679-8⟩
Article dans une revue hal-01743905v1
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Circulating Cell Free Tumor DNA Detection as a Routine Tool forLung Cancer Patient Management

Julie A Vendrell , Frédéric Tran Mau-Them , Benoît Beganton , Sylvain Godreuil , Peter Coopman , et al.
International Journal of Molecular Sciences, 2017, 18 (2), pp.264. ⟨10.3390/ijms18020264⟩
Article dans une revue hal-01784728v1
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Pro-cathepsin D interacts with the extracellular domain of the {beta} chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

Mélanie Beaujouin , Christine Prébois , Danielle Derocq , Valérie Laurent-Matha , Olivier Masson , et al.
Journal of Cell Science, 2010, 123 (19), pp.3336-3346. ⟨10.1242/jcs.070938⟩
Article dans une revue inserm-00518213v1
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Adherens Junction and E-Cadherin complexes regulation by epithelial polarity

Peter Coopman , Alexandre Djiane
Cellular and Molecular Life Sciences, 2016, ⟨10.1007/s00018-016-2260-8⟩
Article dans une revue inserm-01332606v1
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La résistance aux inhibiteurs de BRAF, les leçons de la clinique

Cylia Dahmani , Eulalie Corre , Sarah Dandou , Alain Mangé , Ovidiu Radulescu , et al.
Médecine/Sciences, 2022, 38 (6-7), pp.570-578. ⟨10.1051/medsci/2022083⟩
Article dans une revue hal-03805000v1
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The therapeutic effectiveness of 177Lu-lilotomab in B-cell non- Hodgkin lymphoma involves modulation of G2/M cell cycle arrest

Alexandre Pichard , Sara Marcatili , Jihad Karam , Julie Constanzo , Riad Ladjohounlou , et al.
Leukemia, 2019, 34 (5), pp.1315-1328. ⟨10.1038/s41375-019-0677-4⟩
Article dans une revue inserm-03024614v1