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A p53 score derived from TP53 CRISPR/Cas9 HMCLs predicts survival and reveals major role of BAX in BH3 mimetics response

 Romane Durand , Géraldine Descamps , Christelle Dousset , Céline Bellanger , Sophie Maïga , et al.
Blood, In press, ⟨10.1182/blood.2023021581⟩
Article dans une revue hal-04359884v1
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Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells

 Benoit Tessoulin , Géraldine Descamps , Christelle Dousset , Martine Amiot , Catherine Pellat-Deceunynck
Frontiers in Oncology, 2019, ⟨10.3389/fonc.2019⟩
Article dans une revue inserm-02055153v1
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p53 regulates CD46 expression and measles virus infection in myeloma cells

 Anne Lok , Géraldine Descamps , Benoit Tessoulin , David Chiron , Marion Eveillard , et al.
Blood Advances, 2018, 2 (23), pp.3492-3505. ⟨10.1182/bloodadvances.2018025106⟩
Article dans une revue inserm-01957487v1
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TLR9 Ligand Induces the Generation of CD20+ Plasmablasts and Plasma Cells from CD27+ Memory B-Cells

 Alexandrine Geffroy-Luseau , David Chiron , Géraldine Descamps , Gaëtan Jégo , Martine Amiot , et al.
Frontiers in Immunology, 2011, 2, ⟨10.3389/fimmu.2011.00083⟩
Article dans une revue inserm-03290331v1
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CARD11 gain of function upregulates BCL2A1 and promotes resistance to targeted therapies combination in B-cell lymphoma

 Salomé Decombis , Céline Bellanger , Yannick Le Bris , Candice Madiot , Jane Jardine , et al.
Blood, In press, ⟨10.1182/blood.2023020211⟩
Article dans une revue hal-04195394v1
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Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma

 David Chiron , Christelle Dousset , Carole Brosseau , Cyrille Touzeau , Sophie Maïga , et al.
Oncotarget, 2015, 6 (11), pp.8750-9. ⟨10.18632/oncotarget.3275⟩
Article dans une revue inserm-02534385v1
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Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups

 Patricia Gomez-Bougie , Maxime Halliez , Sophie Maïga , Catherine Godon , Charlotte Kervoëlen , et al.
Cancer Biology and Therapy, 2015, 16 (1), pp.60-5. ⟨10.4161/15384047.2014.986997⟩
Article dans une revue inserm-02534388v1
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Decitabine and Melphalan Fail to Reactivate p73 in p53 Deficient Myeloma Cells

 Pierre-Samuel Gillardin , Géraldine Descamps , Sophie Maiga , Benoit Tessoulin , Hanane Djamai , et al.
International Journal of Molecular Sciences, 2017, 19 (1), ⟨10.3390/ijms19010040⟩
Article dans une revue inserm-01691503v1
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The origin of the plasma-cell heterogeneity

 Catherine Pellat-Deceunynck , Thierry Defrance
Frontiers in Immunology, 2015, 6
Article dans une revue inserm-01820475v1
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RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53 abnormal myeloma cells independently of the p53 pathway

 Sylvanie Surget , Géraldine Descamps , Carole Brosseau , Vincent Normant , Sophie Maïga , et al.
BMC Cancer, 2014, 14 (14), pp.437. ⟨10.1186/1471-2407-14-437⟩
Article dans une revue inserm-03290484v1
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A Functional, New Short Isoform of Death Receptor 4 in Ewing's Sarcoma Cell Lines May be Involved in TRAIL Sensitivity/Resistance Mechanisms

 Gaëlle Picarda , Sylvanie Surget , Romain Guiho , Stéphane Teletchea , Martine Berreur , et al.
Molecular Cancer Research, 2012, 10 (3), pp.336-346. ⟨10.1158/1541-7786.MCR-11-0390⟩
Article dans une revue inserm-02438684v1

Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy

 Denis Puthier , Catherine Pellat-Deceunynck , S. Barille , N. Robillard , M. J. Rapp , et al.
Leukemia, 1999, 13 (2), pp.289--294
Article dans une revue hal-01595832v1

Toll-like receptors: lessons to learn from normal and malignant human B cells

 David Chiron , Isabelle Bekeredjian-Ding , Catherine Pellat-Deceunynck , Régis Bataille , Gaetan Jego
Blood, 2008, ⟨10.1182/blood-2008-02-140673⟩
Article dans une revue inserm-02459027v1
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Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways

 Benoit Tessoulin , Agnès Moreau-Aubry , Géraldine Descamps , Patricia Gomez-Bougie , Sophie Maiga , et al.
Journal of Hematology and Oncology, 2018, 11 (1), pp.137. ⟨10.1186/s13045-018-0679-0⟩
Article dans une revue inserm-01958772v1
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The REFRACT-LYMA cohort study: a French observational prospective cohort study of patients with mantle cell lymphoma.

 Matthieu Hanf , David Chiron , Sophie de Visme , Cyrille Touzeau , Hervé Maisonneuve , et al.
BMC Cancer, 2016, 16 (1), pp.802. ⟨10.1186/s12885-016-2844-6⟩
Article dans une revue hal-01524145v1
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Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis

 Sophie Bustany , Julie Cahu , Géraldine Descamps , Catherine Pellat-Deceunynck , Brigitte Sola
Journal of Hematology and Oncology, 2015, 8 (1), pp.40. ⟨10.1186/s13045-015-0135-3⟩
Article dans une revue inserm-01237704v1
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CSF1R and BTK inhibitions as novel strategies to disrupt the dialogue between mantle cell lymphoma and macrophages

 Antonin Papin , Benoit Tessoulin , Céline Bellanger , Anne Moreau , Yannick Le Bris , et al.
Leukemia, In press, Epub ahead of print
Article dans une revue inserm-02081007v1
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Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/ BAK hetero-complexes

 Carolane Seiller , Sophie Maiga , Cyrille Touzeau , Céline Bellanger , Charlotte Kervoëlen , et al.
Cell Death and Disease, 2020, 11, pp.316. ⟨10.1038/s41419-020-2505-1⟩
Article dans une revue inserm-02563554v1
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Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells

 Benoit Tessoulin , Geraldine Descamps , Christelle Dousset , Martine Amiot , Catherine Pellat-Deceunynck
Frontiers in Oncology, 2019, 9, ⟨10.3389/fonc.2019.00128⟩
Article dans une revue inserm-04154942v1
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p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell

 Benoit Tessoulin , Marion Eveillard , Anne Lok , David Chiron , Philippe Moreau , et al.
Blood Reviews, 2017, [Epub ahead of print]. ⟨10.1016/j.blre.2017.03.001⟩
Article dans une revue inserm-01493742v1
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BH3 profiling as a tool to identify acquired resistance to venetoclax in multiple myeloma

 Christelle Dousset , Sophie Maïga , Patricia Gomez-Bougie , Joy Le Coq , Cyrille Touzeau , et al.
British Journal of Haematology, 2016, [Epub ahead of print]. ⟨10.1111/bjh.14251⟩
Article dans une revue inserm-01353369v1
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Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma

 C Grandclément , C Estoppey , E Dheilly , M Panagopoulou , T Monney , et al.
Nature Communications, 2024, 15, pp.2054. ⟨10.1038/s41467-024-46310-y⟩
Article dans une revue hal-04496386v1
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Generation and characterization of novel anti-DR4 and anti-DR5 antibodies developed by genetic immunization

 Agathe Dubuisson , Cécile Favreau , Eric Fourmaux , Sabrina Lareure , Rafael Rodrigues-Saraiva , et al.
Cell Death and Disease, 2019, 10 (2), ⟨10.1038/s41419-019-1343-5⟩
Article dans une revue inserm-02006230v1
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Mcl-1L cleavage is involved in TRAIL-R1– and TRAIL-R2–mediated apoptosis induced by HGS-ETR1 and HGS-ETR2 human mAbs in myeloma cells

 Emmanuelle Menoret , Patricia Gomez-Bougie , Alexandrine Geffroy-Luseau , Sylvanne Daniels , Philippe Moreau , et al.
Blood, 2006, 108, pp.1346 - 1352. ⟨10.1182/blood-2005-12-007971⟩
Article dans une revue inserm-03290205v1
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Pre-clinical characterization of ISB 1342, a CD38xCD3 T-cell engager for relapsed/refractory multiple myeloma

 Blandine Pouleau , Carole Estoppey , Perrine Suere , Emilie Nallet , Amélie Laurendon , et al.
Blood, 2023, 142 (3), pp.260-273. ⟨10.1182/blood.2022019451⟩
Article dans une revue hal-04240669v1
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BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment

 Patricia Gomez-Bougie , Sophie Maïga , Benoit Tessoulin , Jessie Bourcier , Antoine Bonnet , et al.
Blood, 2018, Epub ahead of print. ⟨10.1182/blood-2018-03-836718⟩
Article dans une revue inserm-01900681v1
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Emergence and evolution of TP53 mutations are a key feature of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide.

 Laurence Lodé , Audrey Ménard , Laurent Flet , Steven Richebourg , Marion Loirat , et al.
Haematologica, 2018, Epub ahead of print. ⟨10.3324/haematol.2017.181404⟩
Article dans une revue inserm-01691580v1
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Myeloma Cell Self-Renewal Depends on JAG2 Expression and Is Mediated by IGF1 or SCF Loop

 David Chiron , Sophie Maiga , Géraldine Descamps , Severine Marionneau-Lambot , Catherine Pellat-Deceunynck
ASH meeting 2010, Dec 2010, Orlando, United States. pp.127, ⟨10.1182/blood.V116.21.127.127⟩
Communication dans un congrès inserm-02459063v1
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The REFRACT-LYMA cohort study: a French observational prospective cohort study of patients with mantle cell lymphoma

 Matthieu Hanf , David Chiron , Sophie de Visme , Cyrille Touzeau , Hervé Maisonneuve , et al.
BMC Cancer, 2016, 16 (1), pp.802. ⟨10.1186/s12885-016-2844-6⟩
Article dans une revue inserm-01381110v1
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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.

 Jérôme Moreaux , Bernard Klein , Régis Bataille , Géraldine Descamps , Sophie Maïga , et al.
Haematologica, 2011, 96 (4), pp.574-82. ⟨10.3324/haematol.2010.033456⟩
Article dans une revue inserm-00550232v1
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