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Peggy GANDIA

38
Documents

Présentation

Professor of pharmacology/pharmacokinetics, head of the Pharmacology department at the school of pharmaceutical sciences of the Paul Sabatier University, and head of the Laboratory of Pharmacokinetics and Toxicology of the Toulouse University Hospital. I'm the coordinator of medical biology interns for the South of France. As a researcher, she is member of the research unit “UMR INTHERES” at the Toulouse National Veterinary School. This research unit is specialised in therapeutic innovations and resistance issues in the field of anti-infective therapeutics. I have published more than 80 papers in international journal (H-index: 17). Since 2018, I'm a member of the European CONCEPTION Consortium. The European CONCEPTION consortium was created in 2018 to document the passage of drugs in breast milk and the risks for the breastfed baby in case of drug intake by its mother. The project is planned to last 4 years and consists of several work packages.

Publications

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Exploration of the relationship between cumulative exposure to tobramycin and ototoxicity in patients with cystic fibrosis

Justine Madaule , Félix Valenzuela , Marie Mittaine , Yohan Gallois , Blandine Baladi
Journal of Cystic Fibrosis, 2023, pp.1-5. ⟨10.1016/j.jcf.2023.04.002⟩
Article dans une revue hal-04086358v1
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Hypoalbuminemia and Pharmacokinetics: When the Misunderstanding of a Fundamental Concept Leads to Repeated Errors over Decades

Peggy Gandia , Sarah Decheiver , Manon Picard , Romain Guilhaumou , Sarah Baklouti
Antibiotics, 2023, 12 (3), pp.515. ⟨10.3390/antibiotics12030515⟩
Article dans une revue hal-04061765v1
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“De-Shrinking” EBEs: The Solution for Bayesian Therapeutic Drug Monitoring

Sarah Baklouti , Peggy Gandia , Didier Concordet
Clinical Pharmacokinetics, 2022, 61 (5), pp.749 - 757. ⟨10.1007/s40262-021-01105-y⟩
Article dans une revue hal-03670618v1

Why Is It Desirable To Do the External Evaluation of a Population Pharmacokinetic Model?

Sarah Baklouti , S. Marolleau , P. Chavanet , E. Bonnet , Didier Concordet
Antimicrobial Agents and Chemotherapy, 2022, 66 (1), ⟨10.1128/AAC.01493-21⟩
Article dans une revue hal-03578727v1

Safety of Pyrazinamide for the Treatment of Tuberculosis in Older Patients Over 75 Years of Age

Stella Rousset , Margaux Lafaurie , Hélène Guet-Revillet , Caroline Protin , Jean Le Grusse
Drugs and Aging, 2021, 38 (1), pp.43-52. ⟨10.1007/s40266-020-00811-9⟩
Article dans une revue hal-03158686v1

Maraviroc exposure is influenced by exogenous thyrotoxicosis

David Metsu , Christian Aquilina , Pierre Delobel , Peggy Gandia , Frédérique Savagner
AIDS. Official journal of the international AIDS Society, 2021, 35 (4), pp.701-703. ⟨10.1097/QAD.0000000000002754⟩
Article dans une revue hal-03473015v1

Efficacy of dihydroartemisinin/piperaquine in patients with noncomplicated Plasmodium falciparum malaria in Yaoundé, Cameroon

Mélissa Mairet-Khedim , Sandrine Nsango , Christelle Ngou , Sandie Menard , Camille Roesch
Journal of Antimicrobial Chemotherapy, 2021, 76 (11), pp.3037-3044. ⟨10.1093/jac/dkab281⟩
Article dans une revue pasteur-03494748v1
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Neglecting plasma protein binding in COVID-19 patients leads to a wrong interpretation of lopinavir overexposure

Francoise Stanke-Labesque , Didier Concordet , Zoubir Djerada , Stephane Bouchet , Caroline Solas
Clinical Pharmacology and Therapeutics, 2021, Therapeutic Innovations in Infectious Diseases, 109 (4), pp.1030-1033. ⟨10.1002/cpt.2196⟩
Article dans une revue hal-03191652v1
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Determining the therapeutic range for ribavirin in transplant recipients with chronic hepatitis E virus infection

Midas B Mulder , Robert A Man , Nassim Kamar , Gűlcan Durmaz , Joep Bruijne
Journal of Viral Hepatitis, 2021, 28 (2), pp.431-435. ⟨10.1111/jvh.13432⟩
Article dans une revue hal-03580025v1
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Tacrolimus Intrapatient Variability After Switching From Immediate or Prolonged-Release to Extended-Release Formulation, After an Organ Transplantation

Arnaud del Bello , Clotilde Gaible , Nathalie Longlune , Anne-Laure Hebral , Lauren Esposito
Frontiers in Pharmacology, 2021, 12, ⟨10.3389/fphar.2021.602764⟩
Article dans une revue hal-03623073v1

Serious Ivermectin Toxicity and Human ABCB1 Nonsense Mutations

Eloise Baudou , Anne Lespine , Geneviève Durrieu , François André , Peggy Gandia
New England Journal of Medicine, 2020, 383 (8), pp.787--789. ⟨10.1056/NEJMc1917344⟩
Article dans une revue hal-02928174v1

Hydroxychloroquine in Coronavirus Disease 2019 Patients: What Still Needs to Be Known About the Kinetics

Guillaume Martin-Blondel , Stéphanie Ruiz , Marlene Murris , Stanilas Faguer , Véronigue Duhalde
Clinical Infectious Diseases, 2020, 71 (11), pp.2962-2964. ⟨10.1093/cid/ciaa558⟩
Article dans une revue hal-03167732v1
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Comparing ultrafiltration and equilibrium dialysis to measure unbound plasma dolutegravir concentrations based on a design of experiment approach

David Metsu , Thomas Lanot , François Fraissinet , Didier Concordet , Véronique V. Gayrard-Troy
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-69102-y⟩
Article dans une revue hal-02911804v1

Influence of extracorporeal membrane oxygenation on the pharmacokinetics of ceftolozane/tazobactam: an ex vivo and in vivo study

Camille Mané , Clément Delmas , Jean Porterie , Géraldine Jourdan , Patrick Verwaerde
Journal of Translational Medicine, 2020, 18 (1), ⟨10.1186/s12967-020-02381-1⟩
Article dans une revue hal-02940915v1

Refining the therapeutic range of posaconazole and isavuconazole for efficient therapeutic drug monitoring using a bioassay approach

Théo Willeman , Julia Tonini , Cécile Garnaud , Sébastien Bailly , Peggy Gandia
Fundamental & Clinical Pharmacology, 2019, ⟨10.1111/fcp.12507⟩
Article dans une revue hal-02976876v1

Memory impairment following intentional self-poisoning with benzodiazepines

Juliette Salles , Jérémie Pariente , Laurent Schmitt , Dominique Lauque , Thomas Lanot
Journal of Psychopharmacology, 2019, 33 (11), pp.1428-1435. ⟨10.1177/0269881119867609⟩
Article dans une revue hal-03641012v1

Suicide Attempts

Juliette Salles , Bernard Tiret , Adeline Gallini , Peggy Gandia , Christophe Arbus
Suicide and Life-Threatening Behavior, 2019, 50 (1), pp.315-328. ⟨10.1111/sltb.12586⟩
Article dans une revue hal-03464218v1
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Determination of dolutegravir's unbound fraction in human plasma using validated equilibrium dialysis and LC-MS/MS methods

David Metsu , Thomas Lanot , François Fraissinet , Mélanie Picot , Didier Concordet
Clinica Chimica Acta, 2018, 479, pp.56-65. ⟨10.1016/j.cca.2017.12.034⟩
Article dans une revue hal-02621511v1

Antiretroviral unbound concentration during pregnancy: piece of interest in the puzzle?

David Metsu , Pierre-Louis Toutain , Etienne Chatelut , Pierre Delobel , Peggy Gandia
Journal of Antimicrobial Chemotherapy, 2017, 72 (9), pp.2407-2409. ⟨10.1093/jac/dkx176⟩
Article dans une revue hal-01608734v1

Population pharmacokinetics of tracers: A new tool for medical imaging?

Peggy Gandia , Cyril Jaudet , Etienne Chatelut , Didier Concordet
Clinical Pharmacokinetics, 2017, 56 (2), pp.101-106. ⟨10.1007/s40262-016-0437-9⟩
Article dans une revue hal-01607048v1

Population pharmacokinetic approach applied to positron emission tomography: Computed tomography for tumor tissue identification in patients with glioma

Peggy Gandia , Cyril Jaudet , Hendrik Everaert , Johannes Heemskerk , Anne Marie Vanbinst
Clinical Pharmacokinetics, 2017, 56 (8), pp.953-961. ⟨10.1007/s40262-016-0490-4⟩
Article dans une revue hal-01601882v1

Is the unbound concentration of atazanavir of interest in therapeutic drug monitoring?

David Metsu , Patrick Séraissol , Pierre Delobel , Christel Cinq-Frais , Lise Cuzin
Fundamental & Clinical Pharmacology, 2017, ⟨10.1111/fcp.12245⟩
Article dans une revue hal-01907438v1

Quinine unbound concentration is the best marker for therapeutic drug monitoring.

Carlos de Pablos-Martinez , Lydie Porte , François Fraissinet , Antoine Berry , Patrick Séraissol
Thérapie, 2016, 71 (5), pp.487-489. ⟨10.1016/j.therap.2016.02.032⟩
Article dans une revue hal-01601653v1

Quinine unbound concentration has to be used for therapeutic drug monitoring.

Carlos de Pablos-Martinez , Lydie Porte , François Fraissinet , Antoine Berry , Patrick Séraissol
Therapeutic Drug Monitoring, 2016, 38 (4), pp.556-7. ⟨10.1097/FTD.0000000000000304⟩
Article dans une revue hal-02634648v1

Problèmes et difficultés rencontrés lors de la planification et de l'analyse d'un essai de bioéquivalence.

Pierre-Louis Toutain , Peggy Gandia , Alain Bousquet‐mélou
La Lettre du Pharmacologue, 2014, 28 (2), pp.37-50
Article dans une revue hal-02630493v1

Inhibition of T-cell activation and proliferation by mycophenolic acid in patients awaiting liver transplantation: PK/PD relationships.

Aurélie Prémaud , Annick Rousseau , Gyasi Johnson , Cindy Canivet , Peggy Gandia
Pharmacological Research, 2011, 63 (5), pp.432-8. ⟨10.1016/j.phrs.2011.01.005⟩
Article dans une revue inserm-00926481v1

Clomipramine in breast milk: a case study

D Khachman , Peggy Gandia , Ma Gaillard , P Seraissol , P Mendousse
Journal de Pharmacie Clinique, 2009, pp.33-38
Article dans une revue hal-02654422v1

Polyoma BK virus-associated nephropathy in kidney-transplant patients: Effects of leflunomide on T-cell functions and disease outcome.

Cindy Canivet , Lionel Rostaing , Sylvain Galvani , Torsten Böhler , Peggy Gandia
International Immunopharmacology, 2009, 9 (9), pp.1131-6. ⟨10.1016/j.intimp.2009.05.004⟩
Article dans une revue inserm-00410375v1

Transfer of benzodiazepines into breast milk: clinical and analytical aspects

D Khachman , Peggy Gandia , F Sena , C Tortissier , P Seraissol
Annale de Toxicologie Analytique, 2008, pp.165-179
Article dans une revue hal-02661242v1

Pharmacodynamic effects of cinacalcet after kidney transplantation: once- versus twice-daily dose.

Nassim Kamar , Isabelle Gennero , Luciana Spataru , Laure Esposito , Joelle Guitard
Nephrology Dialysis Transplantation, 2008, 23 (11), pp.3720-6. ⟨10.1093/ndt/gfn345⟩
Article dans une revue inserm-00409076v1

Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter.

Guylène Lafforgue , Cécile Arellano , Christelle Vachoux , John Woodley , Claude Philibert
Fundamental & Clinical Pharmacology, 2008, 22 (2), pp.189-201. ⟨10.1111/j.1472-8206.2008.00572.x⟩
Article dans une revue hal-00517537v1

Exploring of primary brains tumor heterogeneity at a voxel level with dynamic 18F-fluoro-ethyl-tyrosine (18F-FET) positon emission tomography

Cyril Jaudet , Peggy Gandia , Henrik Everaert , Rémi Servien , J.W. Heemskerk
Congress of the Radiological Sociey of North-America (RSNA), Nov 2015, Chicago, United States. pp.NM219-SD-TUA8
Communication dans un congrès hal-03277832v1