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Patrizia Giannoni


 

 

EDUCATION


2008            Doctorat ès Pharmacologie et Toxicologie délivré par l'Université de Florence, Italie

2004             Doctorat ès Pharmacie cum laude délivré par l'Université de Florence, Italie

 

PARCOURS PROFESSIONNEL

2018- present      Maître de conférences;  Université de Nimes,  Equipe Chrome (EA7352),  Nimes, France

2016- 2018           ATER en biologie; Université de Nimes,  Equipe Chrome (EA7352),  Nimes, France

2011-2016            Stage post-doctoral; Institut de Génomique Fonctionnelle (IGF), Montpellier, France

2008-2011            Stage post-doctoral; New York University Medical center, New York, NY, USA 


Journal articles20 documents

  • Patrizia Giannoni, Silvia Fossati, Elena Marcello, Sylvie Claeysen. Editorial: Identification of Multiple Targets in the Fight Against Alzheimer's Disease. Frontiers in Aging Neuroscience, Frontiers, 2020, 1, ⟨10.3389/fnagi.2020.00169⟩. ⟨hal-02871844⟩
  • Sandrine Bayle, B Martinez-Arribas, S. Jarraud, Patrizia Giannoni, L Garrelly, et al.. Development of a DGGE method to explore Legionella communities. Heliyon, Elsevier 2020, 6 (1), pp.e03149. ⟨10.1016/j.heliyon.2019.e03149⟩. ⟨hal-02430628⟩
  • Patrizia Giannoni, Sylvie Claeysen, Francesco Noe, Nicola Marchi. Peripheral Routes to Neurodegeneration: Passing Through the Blood–Brain Barrier. Frontiers in Aging Neuroscience, Frontiers, 2020, 12, pp.3. ⟨10.3389/fnagi.2020.00003⟩. ⟨hal-02465771⟩
  • Christophe Rochais, Cédric Lecoutey, Katia Hamidouche, Patrizia Giannoni, Florence Gaven, et al.. Donecopride, a Swiss army knife with potential interest against Alzheimer's disease. British Journal of Pharmacology, Wiley, In press, ⟨10.1111/bph.14964⟩. ⟨hal-02428730⟩
  • Patrizia Giannoni, Jerome Badaut, Cyril Dargazanli, Alexis Fayd'Herbe de Maudave, Wendy Klement, et al.. The pericyte–glia interface at the blood–brain barrier. Clinical Science, Portland Press, 2018, 132 (3), pp.361-374. ⟨10.1042/CS20171634⟩. ⟨hal-02074159⟩
  • Kévin Baranger, Patrizia Giannoni, Stéphane Girard, Sarah Girot, Florence Gaven, et al.. Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease. Neuropharmacology, Elsevier, 2017, 126, pp.128-141. ⟨10.1016/j.neuropharm.2017.08.031⟩. ⟨hal-01799428⟩
  • Farron Mcintee, Patrizia Giannoni, Steven Blais, George Sommer, Thomas Neubert, et al.. In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein. Frontiers in Aging Neuroscience, Frontiers, 2016, 8, ⟨10.3389/fnagi.2016.00223⟩. ⟨hal-01705732⟩
  • Patrizia Giannoni, Margarita Arango-Lievano, Ines das Neves, Marie-Claude Rousset, Kévin Baranger, et al.. Cerebrovascular pathology during the progression of experimental Alzheimer's disease. Neurobiology of Disease, Elsevier, 2016, 88, pp.107-117. ⟨10.1016/j.nbd.2016.01.001⟩. ⟨hal-01477817⟩
  • Margarita Arango-Lievano, Patrizia Giannoni, Sylvie Claeysen, Nicola Marchi, Freddy Jeanneteau. Longitudinal in vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases. Journal of visualized experiments : JoVE, JoVE, 2016, ⟨10.3791/54796⟩. ⟨hal-02368047⟩
  • Silvia Fossati, Patrizia Giannoni, Maria Solesio, Sarah Cocklin, Erwin Cabrera, et al.. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain. Neurobiology of Disease, Elsevier, 2016, 86, pp.29-40. ⟨10.1016/j.nbd.2015.11.006⟩. ⟨hal-01997866⟩
  • Christophe Rochais, Cédric Lecoutey, Florence Gaven, Patrizia Giannoni, Katia Hamidouche, et al.. Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride. Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (7), pp.3172-3187. ⟨10.1021/acs.jmedchem.5b00115⟩. ⟨hal-02043873⟩
  • Sylvie Claeysen, Joël Bockaert, Patrizia Giannoni. Serotonin: a new hope in Alzheimer's disease?. ACS Chemical Neuroscience, American Chemical Society (ACS), 2015, 6 (7), pp.940-943. ⟨10.1021/acschemneuro.5b00135⟩. ⟨hal-01792388⟩
  • Cédric Lecoutey, Damien Hedou, Thomas Freret, Patrizia Giannoni, Florence Gaven, et al.. Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩. ⟨hal-01800439v2⟩
  • Patrizia Giannoni, Florence Gaven, Dimitri de Bundel, Kévin Baranger, Evelyne Marchetti-Gauthier, et al.. Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer’s disease. Frontiers in Aging Neuroscience, Frontiers, 2013, 5, pp.96. ⟨10.3389/fnagi.2013.00096⟩. ⟨hal-01703910⟩
  • Sylvie Claeysen, Maud Cochet-Bissuel, Romain Donneger, Aline Dumuis, Joël Bockaert, et al.. Alzheimer culprits: cellular crossroads and interplay. Cellular Signalling, Elsevier, 2012, 24 (9), pp.1831-1840. ⟨10.1016/j.cellsig.2012.05.008⟩. ⟨hal-01792371⟩
  • Patrizio Blandina, Leonardo Munari, Patrizia Giannoni, Chiara Mariottini, Maria Passani. HISTAMINE NEURONAL SYSTEM AS THERAPEUTIC TARGET FOR THE TREATMENT OF COGNITIVE DISORDERS. Future Neurology, Future Medicine, 2010, ⟨10.2217/fnl.10.30⟩. ⟨hal-01793879⟩
  • Patrizia Giannoni, Andrew Medhurst, M. Passani, M. Giovannini, C. Ballini, et al.. Regional Differential Effects of the Novel Histamine H3 Receptor Antagonist 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on Histamine Release in the Central Nervous System of Freely Moving Rats. Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2009, 332 (1), pp.164 - 172. ⟨10.1124/jpet.109.158444⟩. ⟨hal-01764810⟩
  • Patrizia Giannoni, Maria-Beatrice Passani, Daniele Nosi, Paul L Chazot, Fiona C Shenton, et al.. Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat. European Journal of Neuroscience, Wiley, 2009. ⟨hal-01756945⟩
  • Maria Beatrice Passani, Corrado Bucherelli, Elisabetta Baldi, Patrizio Blandina, Patrizia Giannoni. Histamine in the brain: Beyond sleep and memory. Biochemical Pharmacology, Elsevier, 2007, 73 (8), pp.1113 - 1122. ⟨10.1016/j.bcp.2006.12.002⟩. ⟨hal-01762502⟩
  • Gabriele Cenni, Patrizio Blandina, Ken Mackie, Daniele Nosi, Lucia Formigli, et al.. Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain. European Journal of Neuroscience, Wiley, 2006, 24 (6), pp.1633 - 1644. ⟨10.1111/j.1460-9568.2006.05046.x⟩. ⟨hal-01764807⟩

Book sections3 documents

Conference papers8 documents

  • Patrizia Giannoni, Florence Gaven, Sylvie Claeysen. Caractérisation immunohistologique de la pathologie amyloïde et des symptômes associés dans un modèle murin dela maladie d'Alzheimer. (Conférencière invitée). AFH: association française d'histotechnologie, Jun 2015, Montpellier, France. ⟨hal-02918582⟩
  • Patrizia Giannoni, Kevin Baranger, Sarah Girot, Stéphane Girard, Florence Gaven, et al.. Memory deficits of 5xFAD mice in the olfactory H maze test correlate with plaques development and are prevented by 5-HT4R agonist treatments.. AAIC, Jul 2014, Copenhague, Denmark. ⟨hal-02918560⟩
  • Patrizia Giannoni, Florence Gaven, Kevin Baranger, Santiago Rivera, Philippe Marin, et al.. Activation chronique du récepteur de la sérotonine de type 4 : Effet préventif dans un model murin de la maladied’Alzheimer. (Conférencière invitée). Réunion francophone sur la maladie d'Alzheimer, Jun 2014, Montpellier, France. ⟨hal-02918585⟩
  • Patrizia Giannoni, Florence Gaven, Kevin Baranger, Santiago Rivera, Philippe Marin, et al.. New insights in molecular aspects of Alzheimer’s disease. Conférencière invitée.. Sindem, Mar 2013, Perugia, Italy. ⟨hal-02918588⟩
  • Patrizia Giannoni, Florence Gaven, Kevin Baranger, Santiago Rivera, Philippe Marin, et al.. 5-HT4 agonists: novel promising agents for AD prevention. (Conférencière invitée). 36 th meeting of Societa’ Italiana di Farmacologia, 2013, Turin (Italie), October 23, Oct 2013, Turin, Italy. ⟨hal-02918587⟩
  • Patrizia Giannoni, Florence Gaven, Kevin Baranger, Santiago Rivera, Philippe Marin, et al.. Prodromal stimulation of 5-HT4 receptors reduces amyloid pathology in 5XFAD mice.. Club de neuroprotection, Nov 2012, Paris, France. ⟨hal-02918562⟩
  • Patrizia Giannoni, Maria Beatrice Passani, Daniele Nosi, Andrew Medhurst, Paul L Chazot, et al.. Detection of functional heterogeneity of histaminergic neurons in response to GSK189254, a novel H3 antagonist.. 36 th meeting of the European Histamine Research Society, May 2007, Florence, Italy. ⟨hal-02918563⟩
  • Patrizia Giannoni, Gabriele Cenni, Maria Beatrice Passani, Pier Francesco Mannaioni, Andrew Medhurst, et al.. Different response to GABAa or H3 antagonists suggest the existence of distinct subpopulations among histaminergic neurons.. 35 th meeting of the European Histamine Research Society, May 2006, Delphes, Greece. ⟨hal-02918566⟩

Poster communications6 documents

  • Patrizia Giannoni, Bérengère Coupé, Florence Gaven, Kevin Baranger, Santiago Rivera, et al.. Impact du microbiote intestinal dans un modèle murin de maladie d’Alzheimer.. Réunion francophone sur la maladie d’Alzheimer et les syndromes apparentés, Jun 2016, Lyon, France. ⟨hal-02917762⟩
  • Patrizia Giannoni, Yacine Belkacemi, Marie-Claude Rousset, Baddreddine Boussadia, Florence Gaven, et al.. Longitudinal cerebrovascular changes in a genetic model of Alzheimer’s disease.. AD/PD, Mar 2015, Nice, France. ⟨hal-02918542⟩
  • Patrizia Giannoni, Margarita Arango-Lievano, Ines das Neves, Marie-Claude Rousset, Kevin Baranger, et al.. Time dependent vascular pericyte changes in a genetic model of Alzheimer’s disease.. CBV: Conference on Cerebral Vascular Biology, Jul 2015, Paris, France. ⟨hal-02917765⟩
  • Patrizia Giannoni, Florence Gaven, Kevin Baranger, Santiago Rivera, Philippe Marin, et al.. 5 HT4 agonists: novel promising agents for AD prevention.. Congrès des Neurosciences Francaises, May 2013, Lyon, France. ⟨hal-02918543⟩
  • Patrizia Giannoni, Florence Gaven, Kevin Baranger, Santiago Rivera, Philippe Marin, et al.. 5 HT4 agonists: novel promising agents for AD prevention.. AD/PD 2013, Mar 2013, Florence, Italy. ⟨hal-02918547⟩
  • Patrizia Giannoni, Gabriele Cenni, Maria Beatrice Passani, Pier Francesco Mannaioni, Andrew Medhurst, et al.. Functional heterogeneity of histaminergic neurons suggest interesting applications of GSK189254, a novel H3 receptor antagonist. 33 rd meeting of Societa’ Italiana di Farmacologia, Jun 2007, Cagliari, Italy. ⟨hal-02918555⟩