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Cytochrome P450 enzymes mechanism based inhibitors: Common sub-structures and reactivity

Elena Fontana , Patrick M. Dansette , Sonia Maria Poli
Current Drug Metabolism, 2005, 6, pp.413-454. ⟨10.2174/138920005774330639⟩
Article dans une revue hal-00068554v1
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Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, cis-Dihydroxylation and Epoxidation

Derek Boyd , Narain Sharma , Paul Stevenson , Patrick Hoering , Christopher Allen , et al.
International Journal of Molecular Sciences, 2022, 23, ⟨10.3390/ijms23020909⟩
Article dans une revue hal-03656571v1

THE STRUCTURE OF A SUBSTRATE COMPLEX OF MAMMALIAN CYTOCHROME P450 2C 5 AT 2.3A RESOLUTION : EVIDENCE FOR MULTIPLE SUBSTRATE BINDING MODES

Michael R. Wester , Eric F. Johnson , Cristina Marques-Soares , Patrick M. Dansette , Daniel Mansuy , et al.
Biochemistry, 2003, 42, pp.6370-6379
Article dans une revue hal-00018700v1
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Identification of liver protein targets modified by tienilic acid metabolites using a two-dimensional Western blot-mass spectrometry approach

Ruth Menque Methogo , Patrick M. Dansette , Klaus Klarskov
International Journal of Mass Spectrometry, 2007, 268 (2-3), pp.284-295. ⟨10.1016/j.ijms.2007.06.002⟩
Article dans une revue hal-00192244v1

Kinetics of tienilic acid bioactivation and functional generation of drug–protein adducts in intact rat hepatocytes

Maria Pilar López-García , Patrick M. Dansette , Julio Coloma
Biochemical Pharmacology, 2005, 70, pp.1870-1882. ⟨10.1016/j.bcp.2005.09.026⟩
Article dans une revue istex hal-00068621v1

Mechanism of H 2 S Formation from the Metabolism of Anetholedithiolethione and Anetholedithiolone by Rat Liver Microsomes

Martin Dulac , Citra Nagarathinam , Patrick M. Dansette , Daniel Mansuy , Jean-Luc Boucher
Drug Metabolism and Disposition, 2019, 47 (10), pp.1061-1065. ⟨10.1124/dmd.119.087205⟩
Article dans une revue hal-02398998v1

STRUCTURE OF MAMMALIAN CYTOCHROME P450 2C5 COMPLEXED WITH DICLOFENAC AT 2.Å RESOLUTION : EVIDENCE FOR AN INDUCED FIT MODEL OF SUBSTRATE BINDING

Michael R. Wester , Eric F. Johnson , Cristina Marques-Soares , Sylvie Dijols , Patrick M. Dansette , et al.
Biochemistry, 2003, 42, pp.9335-9345
Article dans une revue hal-00079218v1

Sulfaphenazole Derivatives as Tools for Comparing Cytochrome P450 2C5 and Human Cytochromes P450 2Cs: Identification of a New High Affinity Substrate Common to Those Enzymes

Cristina Marques-Soares , Sylvie Dijols , Anne-Christine Macherey , Michael R. Wester , Eric F. Johnson , et al.
Biochemistry, 2003, 42, pp.6363-6369. ⟨10.1021/bi027391+S0006-2960(02)07391-9⟩
Article dans une revue hal-00068736v1

SULFAPHENAZOLE DERIVATIVES AS TOOLS FOR COMPARING CYTOCHROME P450 2C5 AND HUMAN CYTOCHROMES P450 2Cs : IDENTIFICATION OF A NEW HIGH AFFINITY SUBSTRATE COMMON TO THOSE ENZYMES

Cristina Marques-Soares , Sylvie Dijols , Anne-Christine Macherey , Michael R. Wester , Eric F. Johnson , et al.
Biochemistry, 2003, 42, pp.6363-6369
Article dans une revue hal-00018698v1

Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid

Armelle Melet , Nadine Assrir , Pascale Jean , Maria Pilar López-García , Cristina Marques-Soares , et al.
Archives of biochemistry and biophysics., 2003, 409, pp.80-91. ⟨10.1016/S0003-9861(02)00548-9⟩
Article dans une revue istex hal-00069626v1
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A NEW THIOPHENE METABOLITE: NADPH, O 2 AND THIOL DEPENDENT FORMATION OF A THIOPHENE HYDRATE FROM (S)-MTPPA BY CYP2C9

Patrick M. Dansette , Shigeyuki Kitamura , Gildas Bertho , Daniel Mansuy
ISSX-JSSX joint symposium, Maui (Hawai) USA, novembre 2005, Nov 2005, Wailea, Maui, United States
Poster de conférence hal-03515695v1
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Preparation of aromatic aldehydes and aromatic acids (14C) and (3H) (laboratoty note)

Patrick M. Dansette , Robert Azerad
Bulletin de la Societe Chimique de France, 1968, 1968 (6), pp.2492-2493
Article dans une revue hal-04332322v1
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Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.

Pierre Lafite , Sylvie Dijols , Darryl C Zeldin , Patrick M Dansette , Daniel Mansuy
Archives of Biochemistry and Biophysics, 2007, 464 (2), pp.155-68. ⟨10.1016/j.abb.2007.03.028⟩
Article dans une revue hal-00191990v1

Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes.

Michael R. Wester , Eric F. Johnson , Cristina Marques-Soares , Patrick M. Dansette , Daniel Mansuy , et al.
Biochemistry, 2003, 42, pp.4370-4379. ⟨10.1021/bi0273922⟩
Article dans une revue istex hal-00068735v1

Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2

Pierre Lafite , François André , Joan P. Graves , Darryl C. Zeldin , Patrick M. Dansette , et al.
International Journal of Molecular Sciences, 2018, 19 (7), pp.2066. ⟨10.3390/ijms19072066⟩
Article dans une revue hal-02180797v1

Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2

Pierre Lafite , Sylvie Dijols , Didier Buisson , Anne-Christine Macherey , Darryl C. Zeldin , et al.
Bioorganic and Medicinal Chemistry Letters, 2006, 16, pp.2777-2780. ⟨10.1016/j.bmcl.2006.02.004⟩
Article dans une revue hal-00068615v1
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Drug metabolism artifacts: formation of cytochrome P450 dependent amide metabonate from thioesters and thiolactones

Patrick M. Dansette , Assia Hessani , Dan Levent , Daniel Mansuy
"20th International Conference on Cytochrome P450"., Aug 2017, Dusseldorf, Germany
Poster de conférence hal-02314472v1
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Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation

Yong Wang , Marie-Aude Richard , Siden Top , Patrick M. Dansette , Pascal Pigeon , et al.
Angewandte Chemie, 2016, 55 (35), pp.10431-10434. ⟨10.1002/anie.201603931⟩
Article dans une revue hal-01345781v1
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Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression

Alejandro Orrico-Sanchez , Laetitia Chausset-Boissarie , Rodolphe Alves de Sousa , Basile Coutens , Sara Rezai Amin , et al.
Molecular Psychiatry, 2020, 25 (6), pp.1245-1259. ⟨10.1038/s41380-019-0548-4⟩
Article dans une revue inserm-03943549v1

Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding.

Michael R. Wester , Eric F. Johnson , Cristina Marques-Soares , Sylvie Dijols , Patrick M. Dansette , et al.
Biochemistry, 2003, 42, pp.9335-9345. ⟨10.1021/bi034556l⟩
Article dans une revue istex hal-00068734v1

Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.

Armelle Melet , Cristina Marques-Soares , Guillaume A. A. Schoch , Anne-Christine Macherey , Maryse Jaouen , et al.
Biochemistry, 2004, 43, pp.15379-15392. ⟨10.1021/bi0489309⟩
Article dans une revue istex hal-00068689v1
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Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

Marie-Aude Richard , Didier Hamels , Pascal Pigeon , Siden Top , Patrick M. Dansette , et al.
ChemMedChem, 2015, 10 (6), pp.981-990. ⟨10.1002/cmdc.201500075⟩
Article dans une revue hal-01230370v1
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Etude sur la biosynthèse de Naphtoquinones végétales et bactériennes

Patrick M Dansette
Biologie végétale. Université Paris Sud - Paris XI, 1972. Français. ⟨NNT : ⟩
Thèse tel-00663831v1
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Cytochrome P450 dependent metabolism of fluindione in vitro in rat and human microsomes and in vivo in rat.

Patrick M. Dansette , Assia Hessani , Virginie Siguret , Catherine Boisson-Vidal , Jean-Luc Boucher , et al.
MDO-JSSX joint confrerence, Oct 2018, Kanazawa, Japan. ⟨10.13140/RG.2.2.30474.31680⟩
Poster de conférence hal-02348026v1

SYNTHESIS AND SPECTROSCOPIC, ELECTROCHEMICAL, AND CATALYTIC PROPERTIES OF A NEW MANGANESE PORPHYRIN BEARING FOUR POSITIVE CHARGES CLOSE TO THE METAL

Constance Bochot , Jean-François Bartoli , Yves Michel Frapart , Patrick M. Dansette , Daniel Mansuy , et al.
Journal of Molecular Catalysis A: Chemical, 2006, 263, pp.200-205
Article dans une revue hal-00110137v1

Mechanism of the Aromatic Hydroxylation of Thiophene by Acid-Catalyzed Peracid Oxidation.

Alexander Treiber , Patrick M. Dansette , Daniel Mansuy
Journal of Organic Chemistry, 2003, 67, pp.7261-7266. ⟨10.1021/jo0202177S0022-3263(02)00217-7⟩
Article dans une revue hal-00069712v1

First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives

Patrick M. Dansette , Gildas Bertho , Daniel Mansuy
Biochemical and Biophysical Research Communications, 2005, 338, pp.450-455. ⟨10.1016/j.bbrc.2005.08.091⟩
Article dans une revue hal-00068627v1
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Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells

Yong Wang , Pascal Pigeon , Wei Li , Jiangkun Yan , Patrick M Dansette , et al.
European Journal of Medicinal Chemistry, 2022, 234, pp.114202. ⟨10.1016/j.ejmech.2022.114202⟩
Article dans une revue hal-03599161v1
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Inhibitory Effect of Trapping Agents of Reactive Intermediates of Sulfur-containing Drugs Against Major Human Cytochrome P450

Patrick M Dansette , Jasleen K Sodhi , Marie Delarosa , Jason S Halladay , James P Driscoll , et al.
20th International Conference on Cytochrome P450 (ICCP 20), Aug 2017, Dusseldorf, Germany.
Poster de conférence hal-03539866v1

MECHANISM OF THE AROMATIC HYDROXYLATION OF THIOPHENE BY ACID-CATALYZED PERACID OXIDATION

Alexander Treiber , Patrick M. Dansette , Daniel Mansuy
Journal of Organic Chemistry, 2003, 67, pp.7261-7266
Article dans une revue hal-00018696v1