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Multiphoton imaging of tumor biomarkers in situ using highly oriented conjugates of single-domain antibodies and quantum dots

Alyona Sukhanova , Hilal Hafian , Michel Pluot , Jacques Cohen , Jean-Marc Millot , et al.
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON), Oct 2015, Novosibirsk, France. pp.119-121, ⟨10.1109/SIBIRCON.2015.7361864⟩
Communication dans un congrès hal-03112342v1

Highly Sensitive Single Domain Antibody–Quantum Dot Conjugates for Detection of HER2 Biomarker in Lung and Breast Cancer Cells

Tatsiana Rakovich , Omar Mahfoud , Bashir Mohamed , Adriele Prina-Mello , Kieran Crosbie-Staunton , et al.
ACS Nano, 2014, 8 (6), pp.5682-5695. ⟨10.1021/nn500212h⟩
Article dans une revue hal-03136167v1

Nanosized Fluorescent Diagnostic Probes Consisting of Single-domain Antibodies Conjugated with Quantum Dots

Alyona Sukhanova , Klervi Even-Desrumeaux , Jean-Marc Millot , Patrick Chames , Daniel Baty , et al.
Materials Today: Proceedings, 2016, 3 (2), pp.518-522. ⟨10.1016/j.matpr.2016.01.083⟩
Article dans une revue hal-03112307v1
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Taking up Cancer Immunotherapy Challenges: Bispecific Antibodies, the Path Forward?

Joanie del Bano , Patrick Chames , Daniel Baty , Brigitte Kerfelec
Antibodies, 2016, 5 (1), ⟨10.3390/antib5010001⟩
Article dans une revue hal-01450799v1
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Les anticorps et scaffold bispécifiques, des médicaments innovants en oncologie impliquant le ciblage des cellules immunitaires

Patrick Chames , Thierry Wurch
Médecine/Sciences, 2019, 35 (12), pp.1072-1082. ⟨10.1051/medsci/2019242⟩
Article dans une revue hal-03017227v1

Nanophotonic tools based on the conjugates of nanoparticles with the single-domain antibodies for multi-photon micrometastases detection and ultrasensitive biochemical assays

Alyona Sukhanova , Fernanda Ramos-Gomes , Patrick Chames , Daniel Baty , Frauke Alves , et al.
Proceedings of SPIE, the International Society for Optical Engineering, 2019, pp.112072A. ⟨10.1117/12.2530233⟩
Article dans une revue hal-03007502v1
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Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation

Pauline Scholler , Damien Nevoltris , Dimitri de Bundel , Simon Bossi , David Moreno-Delgado , et al.
Nature Communications, 2017, 8 (1), pp.1967. ⟨10.1038/s41467-017-01489-1⟩
Article dans une revue hal-01672805v2
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[The future of antibody fragments, made of a single immunoglobulin domain.]

Patrick Chames , Daniel Baty
Médecine/Sciences, 2009, 25 (12), pp.1159-62
Article dans une revue inserm-00443810v1
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Single- and two-photon imaging of human micrometastases and disseminated tumour cells with conjugates of nanobodies and quantum dots

Fernanda Ramos-Gomes , Julia Bode , Alyona Sukhanova , Svetlana V Bozrova , Mara Saccomano , et al.
Scientific Reports, 2018, 8 (1), pp.4595. ⟨10.1038/s41598-018-22973-8⟩
Article dans une revue hal-01765351v1

Bi-photon imaging and diagnostics using ultra-small diagnostic probes engineered from semiconductor nanocrystals and single-domain antibodies

Hilal Hafian , Alyona Sukhanova , Patrick Chames , Daniel Baty , Michel Pluot , et al.
Proceedings of SPIE, the International Society for Optical Engineering, 2012, Nanosystems in Engineering and Medicine, 8548, pp.85480R. ⟨10.1117/12.960493⟩
Article dans une revue hal-03177842v1
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Single-domain antibodies: a versatile and rich source of binders for breast cancer diagnostic approaches.

Klervi Even-Desrumeaux , Patrick Fourquet , Véronique Secq , Daniel Baty , Patrick Chames
Molecular BioSystems, 2012, 8 (9), pp.2385-2394. ⟨10.1039/c2mb25063b⟩
Article dans une revue inserm-00722930v1
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Isolation and characterization of anti-FcgRIII (CD16) llama single-domain antibodies that activate natural killer cells

Ghislaine Béhar , Sophie Sibéril , Agnès Groulet , Patrick Chames , Martine Pugnière , et al.
Protein Engineering, Design and Selection, 2007, 21 (1), pp.1-10. ⟨10.1093/protein/gzm064⟩
Article dans une revue hal-02454965v1

Anti-Mesothelin Nanobodies for Both Conventional and Nanoparticle-Based Biomedical Applications.

Andrew M Prantner , Marc Turini , Brigitte Kerfelec , Shree Joshi , Daniel Baty , et al.
Journal of Biomedical Nanotechnology, 2015, pp.1201-12
Article dans une revue hal-01450786v1
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Single-domain antibody-based and linker-free bispecific antibodies targeting FcγRIII induce potent antitumor activity without recruiting regulatory T cells.

Caroline Rozan , Amélie Cornillon , Corinne Petiard , M. Chartier , G. Behar , et al.
Molecular Cancer Therapeutics, 2013, 12 (8), pp.1481-1491. ⟨10.1158/1535-7163.MCT-12-1012⟩
Article dans une revue hal-02454959v1

Isolation and characterization of anti-Fc{gamma}RIII (CD16) llama single-domain antibodies that activate natural killer cells.

Ghislaine Behar , Sophie Sibéril , Agnès Groulet , Patrick Chames , Martine Pugnière , et al.
Protein Engineering, Design and Selection, 2008, 21 (1), pp.1-10. ⟨10.1093/protein/gzm064⟩
Article dans une revue hal-00258940v1

Phage Display and Selections on Purified Antigens

Magali Colazet , Patrick Chames
Methods in Molecular Biology, 1827, pp.165-178, 2018, ⟨10.1007/978-1-4939-8648-4_9⟩
Chapitre d'ouvrage hal-02146005v1

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

Marion Morgand , Mélanie Bouvin-Pley , Jean-Christophe Plantier , Moreau Alain , Elodie Alessandri , et al.
Journal of Acquired Immune Deficiency Syndromes - JAIDS, 2016, 71 (3), pp.237-245. ⟨10.1097/QAI.0000000000000854⟩
Article dans une revue hal-01314296v1
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Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and co-receptor binding sites of HIV-1 gp120

Julie Matz , Pacal Kessler , Jérome Bouchet , Olivier Combes , Daniel Baty , et al.
Retrovirology, 2012, 9 (Suppl 2), pp.P214
Article dans une revue inserm-00731772v1
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Strong and oriented immobilization of single domain antibodies from crude bacterial lysates for high-throughput compatible cost-effective antibody array generation.

Klervi Even-Desrumeaux , Daniel Baty , Patrick Chames
Molecular BioSystems, 2010, 6 (11), pp.2241-8. ⟨10.1039/c005279e⟩
Article dans une revue inserm-00521371v1
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Nanobody Engineering: Toward Next Generation Immunotherapies and Immunoimaging of Cancer

Timothée Chanier , Patrick Chames
Antibodies, 2019, 8 (1), pp.13. ⟨10.3390/antib8010013⟩
Article dans une revue hal-02002577v1

Oriented conjugates of monoclonal and single-domain antibodies with quantum dots for flow cytometry and immunohistochemistry diagnostic applications

Alyona Sukhanova , Klervi Even-Desrumeaux , Jean-Marc Millot , Patrick Chames , Daniel Baty , et al.
Proceedings of SPIE, the International Society for Optical Engineering, 2012, Colloidal Nanocrystals for Biomedical Applications VII, 8232, pp.82320T. ⟨10.1117/12.905896⟩
Article dans une revue hal-03184792v1
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Engineering of ultra-small diagnostic nanoprobes through oriented conjugation of single-domain antibodies and quantum dots

Igor Nabiev , Alyona Sukhanova , Klervi Even-Desrumeaux , Patrick Chames , Daniel Baty , et al.
2021
Pré-publication, Document de travail hal-03182577v1
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A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy

Marc Turini , Patrick Chames , Pierre Bruhns , Daniel Baty , Brigitte Kerfelec
Oncotarget, 2014, 5 (14), ⟨10.18632/oncotarget.2093⟩
Article dans une revue hal-02115462v1
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Oriented Conjugates of Single-domain Antibodies and Fluorescent Quantum Dots for Highly Sensitive Detection of Tumor-associated Biomarkers in Cells and Tissues

Regina Bilan , Kristina Brazhnik , Patrick Chames , Daniel Baty , Igor Nabiev , et al.
Physics Procedia, 2015, 73, pp.228-234. ⟨10.1016/j.phpro.2015.09.162⟩
Article dans une revue hal-03112376v1

Multiphoton Imaging of Tumor Biomarkers in situ Using Single-domain Antibodies Conjugated with Quantum Dots in a Set Orientation

Alyona Sukhanova , Hilal Hafian , Marc Turini , Patrick Chames , Daniel Baty , et al.
Materials Today: Proceedings, 2016, 3 (2), pp.523-526. ⟨10.1016/j.matpr.2016.01.084⟩
Article dans une revue hal-03112311v1
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Nanobody-CD16 Catch Bond Reveals NK Cell Mechanosensitivity

Cristina González , Patrick Chames , Brigitte Kerfelec , Daniel Baty , Philippe Robert , et al.
Biophysical Journal, 2019, 116 (8), pp.1516-1526. ⟨10.1016/j.bpj.2019.03.012⟩
Article dans une revue hal-02323625v1

Conformational nanobodies reveal tethered epidermal growth factor receptor involved in EGFR/ErbB2 predimers.

Damien Nevoltris , Benjamin Lombard , Elodie Dupuis , Gérard Mathis , Patrick Chames , et al.
ACS Nano, 2015, 9 (2), pp.1388-99. ⟨10.1021/nn505752u⟩
Article dans une revue hal-01450765v1
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Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain

Jiyong Meng , Chanjuan Xu , Pierre-André Lafon , Salomé Roux , Michaël Mathieu , et al.
Nature Chemical Biology, 2022, 18, pp.894-903. ⟨10.1038/s41589-022-01050-2⟩
Article dans une revue hal-03699580v1
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Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer

Antonio Tapia-Galisteo , Íñigo Sánchez Rodríguez , Oscar Aguilar-Sopeña , Seandean Lykke Harwood , Javier Narbona , et al.
OncoImmunology, 2022, 11, ⟨10.1080/2162402x.2022.2034355⟩
Article dans une revue hal-03745498v1
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Masked Selection: A Straightforward and Flexible Approach for the Selection of Binders Against Specific Epitopes and Differentially Expressed Proteins by Phage Display

Klervi Even-Desrumeaux , Damien Nevoltris , Marie Noelle Lavaut , Karima Alim , Jean-Paul Borg , et al.
Molecular and Cellular Proteomics, 2014, 13 (2), pp.653-665. ⟨10.1074/mcp.O112.025486⟩
Article dans une revue hal-02115444v1