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GC content shapes mRNA storage and decay in human cells

Maïté Courel , Yves Clément , Clémentine Bossevain , Dominika Foretek , Olivia Vidal Cruchez , et al.
eLife, 2019, 8, pp.e49708. ⟨10.7554/elife.49708⟩
Article dans une revue hal-03457618v1
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Characterizing isomiR variants within the micro RNA ‐34/449 family

Olivier Mercey , Alexandra Popa , Amélie Cavard , Agnès Paquet , Benoît Chevalier , et al.
FEBS Letters, 2017, 591 (5), pp.693 - 705. ⟨10.1002/1873-3468.12595⟩
Article dans une revue hal-03044331v1

MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib

Sandra Lassalle , Joséphine Zangari , Alexandra Popa , Marius I. Ilie , Véronique Hofman , et al.
Oncotarget, 2016, 7 (21), ⟨10.18632/oncotarget.8458⟩
Article dans une revue hal-02531830v1
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KRAS and NRAS Translation Is Increased upon MEK Inhibitors-Induced Processing Bodies Dissolution

Olivia Vidal-Cruchez , Victoria Nicolini , Tifenn Rete , Karine Jacquet , Roger Rezzonico , et al.
Cancers, 2023, 15 (12), pp.3078. ⟨10.3390/cancers15123078⟩
Article dans une revue hal-04266131v1

Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

Sadal Refae , Jocelyn Gal , Nathalie Ebran , Josiane Otto , Delphine Borchiellini , et al.
Investigational New Drugs, 2020, 38 (1), pp.160-171. ⟨10.1007/s10637-019-00845-w⟩
Article dans une revue hal-02526331v1

Risk predisposition for Crohn disease A "menage a trois" combining IRGM allele, miRNA and xenophagy

Patrick Brest , Pierre Lapaquette , Baharia Mograbi , Arlette Darfeuille-Michaud , Paul Hofman
Autophagy, 2011, 7 (7), pp.786 - 787. ⟨10.4161/auto.7.7.15595⟩
Article dans une revue hal-02650930v1

Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?

Sandra Lassalle , Véronique Hofman , Marius I. Ilie , Christelle Bonnetaud , Marie-Pierre Puisségur , et al.
Endocrine-Related Cancer, 2011, 18 (5), pp.579-594. ⟨10.1530/ERC-10-0283⟩
Article dans une revue hal-00625798v1

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

Amine Belaid , Michaël Cerezo , Abderrahman Chargui , Elisabeth Corcelle-Termeau , Florence Pedeutour , et al.
Cancer Research, 2013, 73 (14), pp.4311-22. ⟨10.1158/0008-5472.CAN-12-4142⟩
Article dans une revue hal-00912953v1

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

Joséphine Zangari , Marius I. Ilie , Florian Rouaud , Laurie Signetti , Mickaël Ohanna , et al.
Nucleic Acids Research, 2017, 8 (34), pp.gkw1284. ⟨10.1093/nar/gkw1284⟩
Article dans une revue hal-02526314v1
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Autophagy : Moving Benchside Promises to Patient Bedsides

Amine Belaïd , Papa Diogop Ndiaye , Harilaos Filippakis , Jérémie Roux , Eric Röttinger , et al.
Current Cancer Drug Targets, 2015, 15 (8), pp.684-702. ⟨10.2174/156800961508151001102452⟩
Article dans une revue hal-02411388v1

GC content shapes mRNA storage and decay in human cells

Maïté Courel , Yves Clément , Clémentine Bossevain , Dominika Foretek , Olivia Vidal Cruchez , et al.
eLife, 2019
Article dans une revue hal-03023372v1

Differential expression and regulation of ADAM17 and TIMP3 in acute inflamed intestinal epithelia.

Annabelle Cesaro , Abakar Abakar-Mahamat , Patrick Brest , Sandra Lassalle , Eric Selva , et al.
AJP - Gastrointestinal and Liver Physiology, 2009, 296 (6), pp.G1332-43. ⟨10.1152/ajpgi.90641.2008⟩
Article dans une revue hal-00408450v1

Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration.

Annabelle Cesaro , Patrick Brest , Véronique Hofman , Xavier Hébuterne , Scott Wildman , et al.
AJP - Gastrointestinal and Liver Physiology, 2010, 299 (1), pp.G32-42. ⟨10.1152/ajpgi.00282.2009⟩
Article dans une revue hal-00553099v1

MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells.

Patrick Brest , Sandra Lassalle , Veronique Hofman , Olivier Bordone , Virginie Gavric Tanga , et al.
Endocrine-Related Cancer, 2011, 18 (6), pp.711-9. ⟨10.1530/ERC-10-0257⟩
Article dans une revue hal-00724345v1

Etiology of Crohn's disease: many roads lead to autophagy

Pierre Lapaquette , Patrick Brest , Paul Hofman , Arlette Darfeuille-Michaud
Journal of Molecular Medicine, 2012, 90 (9), pp.987 - 996. ⟨10.1007/s00109-012-0934-8⟩
Article dans une revue istex hal-02644445v1

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease.

Patrick Brest , Pierre Lapaquette , Mouloud Souidi , Kevin Lebrigand , Annabelle Cesaro , et al.
Nature Genetics, 2011, 43 (3), pp.242-5. ⟨10.1038/ng.762⟩
Article dans une revue hal-04284572v1

Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients

Alexander Falk , Nathalie Yazbeck , Nicolas Guibert , Emmanuel Chamorey , Agnès Paquet , et al.
Lung Cancer, 2018, 121, pp.70-75. ⟨10.1016/j.lungcan.2018.05.009⟩
Article dans une revue hal-02531817v1
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LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition

Sarah Proteau , Imène Krossa , Chrystel Husser , Maxime Guéguinou , Federica Sella , et al.
EMBO Molecular Medicine, 2023, ⟨10.15252/emmm.202317719⟩
Article dans une revue hal-04290204v1
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Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics

Sadal Refae , Jocelyn Gal , Patrick Brest , Damien Giacchero , Delphine Borchiellini , et al.
Scientific Reports, 2020, 10 (1), pp.3565. ⟨10.1038/s41598-020-60437-0⟩
Article dans une revue inserm-02497242v1

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

Joséphine Zangari , Marius Ilie , Florian Rouaud , Laurie Signetti , Mickaël Ohanna , et al.
Nucleic Acids Research, 2018, 46 (7), pp.3813-3814. ⟨10.1093/nar/gky213⟩
Article dans une revue hal-02413532v1

Characterizing isomiR variants within the micro RNA ‐34/449 family

Olivier Mercey , Alexandra Popa , Amelie Cavard , Agnès Paquet , Benoît Chevalier , et al.
FEBS Letters, 2017, 591 (5), pp.693-705. ⟨10.1002/1873-3468.12595⟩
Article dans une revue hal-02531825v1
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Subversion of autophagy in adherent invasive Escherichia coli-infected neutrophils induces inflammation and cell death

Abderrahman Chargui , Annabelle Cesaro , Sanda Mimouna , Mohamed Fareh , Patrick Brest , et al.
PLoS ONE, 2012, 7 (12), ⟨10.1371/journal.pone.0051727⟩
Article dans une revue hal-02649883v1

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease.

Patrick Brest , Pierre Lapaquette , Mouloud Souidi , Kevin Lebrigand , Annabelle Cesaro , et al.
Nature Genetics, 2011, 43 (3), pp.242-5. ⟨10.1038/ng.762⟩
Article dans une revue hal-00626157v1
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Germinal immunogenetics as a predictive factor for immunotherapy

Sadal Refae , Jocelyn Gal , Patrick Brest , Gérard Milano
Critical Reviews in Oncology/Hematology, 2019, 141, pp.146-152. ⟨10.1016/j.critrevonc.2019.06.013⟩
Article dans une revue hal-02531811v1

MiR-223-3p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma

Alexandre Bozec , Joséphine Zangari , Mathilde Butori-Pepino , Marius I. Ilie , Salomé Lalvée , et al.
Oncotarget, 2017, 8 (34), ⟨10.18632/oncotarget.19170⟩
Article dans une revue hal-02531822v1

Gene expression profiling in human gastric mucosa infected with Helicobacter pylori.

Véronique J Hofman , Chimène Moreilhon , Patrick D Brest , Sandra Lassalle , Kevin Le Brigand , et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2007, ⟨10.1038/modpathol.3800930⟩
Article dans une revue hal-00166154v1
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Profiling the Non-genetic Origins of Cancer Drug Resistance with a Single-Cell Functional Genomics Approach Using Predictive Cell Dynamics

Mickael Meyer , Agnès Paquet , Marie-Jeanne Arguel , Ludovic Peyre , Luis Gomes-Pereira , et al.
Cell Systems, 2020, 11 (4), pp.367-374. ⟨10.1016/j.cels.2020.08.019⟩
Article dans une revue hal-03001650v1
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GC content shapes mRNA decay and storage in human cells

Maïte Courel , Yves Clément , Dominika Foretek , Olivia Vidal Cruchez , Zhou Yi , et al.
2019
Pré-publication, Document de travail hal-02415568v1
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Host Polymorphisms May Impact SARS-CoV-2 Infectivity

Patrick Brest , Sadal Refae , Baharia Mograbi , Paul Hofman , Gerard Milano
Trends in Genetics, 2020, 36, pp.813 - 815. ⟨10.1016/j.tig.2020.08.003⟩
Article dans une revue hal-03493508v1

High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness

Elodie Long , Marius I. Ilie , Coraline Bence , Catherine Butori , Eric Selva , et al.
Cancer Medicine, 2016, 5 (6), pp.1022-1030. ⟨10.1002/cam4.661⟩
Article dans une revue hal-02531827v1