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ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells

Emmanuelle Despras , Fayza Daboussi , Olivier Hyrien , Kathrin Marheineke , Patricia Kannouche
Human Molecular Genetics, 2010, 19 (9), pp.1690-1701. ⟨10.1093/hmg/ddq046⟩
Article dans une revue hal-02963047v1

Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum

Alain Sarasin , Samuel Quentin , Nathalie Droin , Mourad Sahbatou , Véronique Saada , et al.
Blood, 2019, 133 (25), pp.2718-2724. ⟨10.1182/blood-2019-01-895698⟩
Article dans une revue hal-02391880v1

XPC and POLH/XPV Genes Mutated in a Genetic Cluster of Xeroderma Pigmentosum Patients in Northeast Brazil

Ligia Pereira Castro , Danilo Batista-Vieira , Tiago Antonio de Souza , Ana Rafaela de Souza Timoteo , Jessica Dayanna Landivar Coutinho , et al.
Frontiers in Genetics, 2022, 12, ⟨10.3389/fgene.2021.784963⟩
Article dans une revue hal-03852553v1
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First description of ultramutated endometrial cancer caused by germline loss-of-function and somatic exonuclease domain mutations in POLE gene

Reginaldo Cruz Alves Rosa , Andrey A Yurchenko , Fernando Chahud , Alfredo Ribeiro-Silva , Mariângela Ottoboni Brunaldi , et al.
Genetics and Molecular Biology, 2020, 43, ⟨10.1590/1678-4685-gmb-2020-0100⟩
Article dans une revue hal-03853568v1

Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers

Laetitia Nebot-Bral , Antoine Hollebecque , Andrey Yurchenko , Louise de Forceville , Mathieu Danjou , et al.
Journal for Immunotherapy of Cancer, 2022, 10 (7), pp.e005059. ⟨10.1136/jitc-2022-005059⟩
Article dans une revue hal-03852523v1

Suleiman-El-Hattab syndrome: a histone modification disorder caused by TASP1 deficiency

Korbinian Riedhammer , Anna Burgemeister , Vincent Cantagrel , Jeanne Amiel , Karine Siquier-Pernet , et al.
Human Molecular Genetics, 2022, 31 (18), pp.3083-3094. ⟨10.1093/hmg/ddac098⟩
Article dans une revue hal-03852536v1
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A homologous recombination defect affects replication-fork progression in mammalian cells.

Fayza Daboussi , Sylvain Courbet , Simone Benhamou , Patricia Kannouche , Malgorzata Z Zdzienicka , et al.
Journal of Cell Science, 2008, 121 (Pt 2), pp.162-6. ⟨10.1242/jcs.010330⟩
Article dans une revue hal-00282471v1
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Suleiman-El-Hattab syndrome: a histone modification disorder caused by TASP1 deficiency

Korbinian M Riedhammer , Anna L Burgemeister , Jeanne Amiel , Vincent Cantagrel , Karine Siquier-Pernet , et al.
Human Molecular Genetics, 2022, 31 (18), pp.3083 - 3094. ⟨10.1093/hmg/ddac098⟩
Article dans une revue hal-03853581v1
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DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability

Barbara Ben Yamin , Sana Ahmed‐seghir , Junya Tomida , Emmanuelle Despras , Caroline Pouvelle , et al.
EMBO Journal, 2021, 49, pp.8120 - 8134. ⟨10.15252/embj.2020104543⟩
Article dans une revue hal-03353667v1
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Changes in the architecture and abundance of replication intermediates delineate the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells

Yann Benureau , Caroline Pouvelle , Pauline Dupaigne , Sonia Baconnais , Eliana Moreira Tavares , et al.
Nucleic Acids Research, 2022, 50 (17), pp.9909-9929. ⟨10.1093/nar/gkac746⟩
Article dans une revue hal-03853540v1
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Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine

Laetitia Nebot-Bral , David Brandao , Loic Verlingue , Etienne Rouleau , Olivier Caron , et al.
European Journal of Cancer, 2017, 84, pp.290-303. ⟨10.1016/j.ejca.2017.07.026⟩
Article dans une revue hal-04265871v1
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XPC and POLH/XPV Genes Mutated in a Genetic Cluster of Xeroderma Pigmentosum Patients in Northeast Brazil

Ligia Pereira Castro , Danilo Batista-Vieira , Tiago Antonio de Souza , Ana Rafaela de Souza Timoteo , Jessica Dayanna Landivar Coutinho , et al.
Frontiers in Genetics, 2022, 12, ⟨10.3389/fgene.2021.784963⟩
Article dans une revue hal-03853572v1
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Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial

Fernanda Mosele , Elise Deluche , Amelie Lusque , Loïc Le Bescond , Thomas Filleron , et al.
Nature Medicine, 2023, 29 (8), pp.2110 - 2120. ⟨10.1038/s41591-023-02478-2⟩
Article dans une revue hal-04187928v1
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Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers

Laetitia Nebot-Bral , Antoine Hollebecque , Andrey A Yurchenko , Louise de Forceville , Mathieu Danjou , et al.
Journal for Immunotherapy of Cancer, 2022, 10, pp.e005059. ⟨10.1136/jitc-2022-005059⟩
Article dans une revue hal-03853375v1
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The SLX4 Complex Is a SUMO E3 Ligase that Impacts on Replication Stress Outcome and Genome Stability

Jean-Hugues Guervilly , Arato Takedachi , Valeria L Naim , Sarah Scaglione , Charly Chawhan , et al.
Molecular Cell, 2015, 57 (1), pp.123-137. ⟨10.1016/j.molcel.2014.11.014⟩
Article dans une revue hal-01429041v1

PUB-NChIP--"in vivo biotinylation" approach to study chromatin in proximity to a protein of interest

Muhammad Shoaib , Arman Kulyyassov , Chloé Robin , Kinga Winczura , Pavel Tarlykov , et al.
Genome Research, 2013, 23 (2), pp.331-340. ⟨10.1101/gr.134874.111⟩
Article dans une revue hal-02159970v1

Why is immunotherapy effective (or not) in patients with MSI/MMRD tumors?

Laetitia Nebot-Bral , Clélia Coutzac , Patricia L Kannouche , Nathalie Chaput
Bulletin du Cancer, 2019, 106 (2), pp.105-113. ⟨10.1016/j.bulcan.2018.08.007⟩
Article dans une revue hal-02425478v1
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In vivo reduction of RAD51 ‐mediated homologous recombination triggers aging but impairs oncogenesis

Gabriel Matos-Rodrigues , Vilma Barroca , Ali‐akbar Muhammad , Elodie Dardillac , Awatef Allouch , et al.
EMBO Journal, 2023, 42 (20), pp.e110844. ⟨10.15252/embj.2022110844⟩
Article dans une revue hal-04256476v1

Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers

Laetitia Nebot-Bral , Antoine Hollebecque , Andrey Yurchenko , Louise de Forceville , Mathieu Danjou , et al.
Journal for Immunotherapy of Cancer, 2022, 10 (7), pp.e005059. ⟨10.1136/jitc-2022-005059⟩
Article dans une revue hal-04542069v1

DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability

Barbara Ben Yamin , Sana Ahmed-Seghir , Junya Tomida , Emmanuelle Despras , Caroline Pouvelle , et al.
EMBO Journal, 2021, 40 (21), ⟨10.15252/embj.2020104543⟩
Article dans une revue hal-04522249v1

Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein.

Agnès Tissier , Patricia Kannouche , Marie-Pierre Reck , Alan R Lehmann , Robert P P Fuchs , et al.
DNA Repair, 2004, 3 (11), pp.1503-14. ⟨10.1016/j.dnarep.2004.06.015⟩
Article dans une revue istex hal-00188915v1
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Targeting genome integrity dysfunctions impedes metastatic potency in non–small cell lung cancer circulating tumor cell–derived explants

Tala Tayoun , Vincent Faugeroux , Marianne Oulhen , Olivier Déas , Judith Michels , et al.
JCI Insight, 2022, 7, ⟨10.1172/jci.insight.155804⟩
Article dans une revue hal-03853591v1
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Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients

Andrey A Yurchenko , Fatemeh Rajabi , Tirzah Braz-Petta , Hiva Fassihi , Alan Lehmann , et al.
Nature Communications, 2023, 14 (1), pp.2561. ⟨10.1038/s41467-023-38311-0⟩
Article dans une revue hal-04187974v1
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In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

Gabriel Matos-Rodrigues , Vilma Barroca , Ali-Akbar Muhammad , Awatef Allouch , Stéphane Koundrioukoff , et al.
2022
Pré-publication, Document de travail hal-03860785v1