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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
42%
Libre accès
65
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
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Effect of sex on gene expression in equine blastocysts.10th International Symposium on Equine Embryo Transfer and technology, University of Pisa, Jun 2022, Pise, Italy
Communication dans un congrès
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Effects of F0 maternal diesel engine exhaust exposure during gestation on F1 and F2 offspring phenotypeESRI, Mar 2022, Paris, France. ⟨10.1016/j.jri.2022.103562⟩
Communication dans un congrès
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Effets d’un régime maternel hypergras sur le transcriptome ovocytaire et embryonnaireSociété Francophone du Diabète, May 2022, Nice, France
Communication dans un congrès
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142 Nulliparity alters gene expression in inner cell mass and trophoblast of equine blastocysts in old mares47TH ANNUAL CONFERENCE OF THE IETS, Jan 2021, online, United States. pp.179, ⟨10.1071/RDv33n2Ab142⟩
Communication dans un congrès
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Effets de l'exposition aux nanoparticules d'or par inhalation sur la fonction placentaire et le phénotype de la descendanceGFP-Groupe de la Francophonie Placentaire, Sep 2021, Nantes, France
Communication dans un congrès
hal-03341279v1
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Impact d’un environnement (pré)-diabétique sur le développement embryonnaire précoceSF-DOHAD, Nov 2021, Jouy-en-Josas, France
Communication dans un congrès
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Long term effects of ART: lessons from animal modelsFertility 2020, Jan 2020, Edinburg, United Kingdom
Communication dans un congrès
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Mares’ age affects embryo ICM and trophoblast RNA-seq transcriptome at about D8International Symposium on Equine Embryo Transfer, Jul 2020, Pisa, Italy. pp.103031, ⟨10.1016/j.jevs.2020.103031⟩
Communication dans un congrès
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Effets de l’exposition maternelle aux nanoparticules d’or par ingestion, pendant la gestation, sur le développement foeto-placentaire et la fonction placentaire, dans un modèle lapin.7. Rencontre du Groupe de la Francophonie Placentaire 2019, Groupe de la francophonie Placentaire (GfP). FRA., Mar 2019, Paris, France. 36 p
Communication dans un congrès
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Effects of maternal au-np exposure by inhalation on foeto-placental development and placental function, in a rabbit modelIPTC, Sep 2019, Salzburg, Austria
Communication dans un congrès
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Epigenetics, developmental programming and nutrition in herbivores10th International Symposium on the Nutrition of Herbivores, Sep 2018, Clermont-Ferrand, France. pp.500, ⟨10.1017/S2040470018000146⟩
Communication dans un congrès
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Détermination de la fenêtre de vulnérabilité à une surnutrition lipidique maternelle pour le développement foeto-placentaire: période pré-conceptionnelle et/ou période gestationnelle?4. Congrès de la SF-Dohad, Société Francophone-DOHaD. FRA., Nov 2018, Grenoble, France. pp.120
Communication dans un congrès
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Effects of maternal Au-NP exposure by ingestion on feto-placental development and placental function, in a rabbit model6. International Conference on Health and Safety issues related to nanomaterials for a socially responsible approach, The Nanosafety Platform-CEA., Nov 2018, Grenoble, France. pp.212
Communication dans un congrès
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Effets de l’exposition maternelle aux nanoparticules d’or par ingestion pendant la gestation, sur le développement foeto-placentaire et la fonction placentaire, dans un modèle lapin4. Congrès de la SF-Dohad, Société Francophone-DOHaD. FRA., Nov 2018, Grenoble, France. pp.120
Communication dans un congrès
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Identification des voies fonctionnelles altérées par un régime maternal hypergras dans l’embryon pré-implantatoire de lapinJournées d’Animation Scientifique du Département PHASE, Apr 2018, Rennes, France
Communication dans un congrès
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Comparative development of embryos and placenta in mammals: how to choose the right biomedical modelCOST Action BM 1308 « Sharing Advances on Large Animal Models - SAALAM », Ludwig Maximilians University of Munich (LMU). DEU. European Cooperation in Science and Technology (COST), BEL., Sep 2017, Halle, Germany
Communication dans un congrès
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Maternal exposure to diluted diesel engine exhaust alters placental function of the first and second generation in rabbit model35. Congrès de la Société Française de Toxicologie Génétique "Conséquences pour l'homme et l'environnement des effets génotoxiques et épigénétiques transgénérationnels", Société Française de Toxicologie Génétique. FRA., Oct 2017, Marseille, France
Communication dans un congrès
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit model18. International Congress on Animal Reproduction (ICAR), International Organisation on Animal Reproduction. FRA., Jun 2016, Tours, France. 676 p
Communication dans un congrès
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Breeding animals for quality products: not only geneticsAnnual Conference of the International Embryo Transfer Society, International Embryo Transfer Society (IETS). USA., Jan 2016, Louisville, United States. ⟨10.1071/RD15353⟩
Communication dans un congrès
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A short periconceptional maternal hyperglycemia is sufficient to disrupt the feto-placental phenotype in a rabbit model41. Annual Conference of IETS, International Embryo Transfer Society (IETS). USA., Jan 2015, Versailles, France. ⟨10.1071/RDv27n1Ab119⟩
Communication dans un congrès
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Maternal exposure to diesel engine exhaust during pregnancy affects early embryo development in a rabbit model41. Annual Conference of IETS, International Embryo Transfer Society (IETS). USA., Jan 2015, Versailles, France. ⟨10.1071/RDv27n1Ab120⟩
Communication dans un congrès
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A short periconceptional maternal hyperglycemia is sufficient to disrupt the feto-placental phenotype in a rabbit model2. Colloque de la SF-DOHaD, Origine Développementale de la santé et des maladies et épigénétique, Société Francophone pour la Recherche et l'Education sur les Origines Développementales, Environnementales et Epigénétiques de la Santé et des Maladies (SF-DOHAD). FRA., Nov 2014, Nantes, France. 57 p
Communication dans un congrès
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Sexual dimorphism starting from the blastocyst stage in response to an imbalanced maternal diet in a rabbit modelMeeting of the International Federation of Placenta Associations (IFPA), Sep 2013, Whistler, British Columbia, Canada. ⟨10.1016/j.placenta.2013.06.054⟩
Communication dans un congrès
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L'expression des gènes embryonnaires et la fonction trophoblastique sont modifiés en réponse à un régime maternel enrichi en lipides et en cholestérol chez le lapinColloque fondateur SF-DOHaD, Société Francophone-DOHaD. FRA., Nov 2012, Paris, France
Communication dans un congrès
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Learning from each other. The mutual benefit of live stock and human reproduction studies28. Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Jul 2012, Istanbul, Turkey. pp.ii35
Communication dans un congrès
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Hyperlipidic hypercholesterolemic maternal died affects early embryonic gene expression and trophoblast functionColloque SF-DOHaD, Société Francophone pour la Recherche et l'Education sur les Origines Développementales, Environnementales et Epigénétiques de la Santé et des Maladies (SF-DOHAD). FRA., Nov 2012, Paris, France
Communication dans un congrès
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Analyses des conséquences de régimes hyperlipidiques administrés à la mère dans la période périconceptionnelle sur l'expression génique précoce de l'embryonJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase), Oct 2010, Tours, France. 1 p
Communication dans un congrès
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Influence of a hyperlidic hypercholesterolemic diet on folliculogenesis and adipophlin expression in the preimplantation embryo in rabbitsProceeding of the 2nd General Meeting GEMINI: Maternal Communication with Gametes and Embryos, Oct 2009, Sardinia, Italy
Communication dans un congrès
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Genomic instability following somatic cell nuclear transfer in cattle60. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2009, Barcelona, Spain
Communication dans un congrès
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Rabbit as a model for embryo development2. International Meeting on Rabbit Biotechnology, Jun 2007, Jouy en Josas, France. 1 p
Communication dans un congrès
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Equine embryo size does matter!48th Annual Conference of the International Society of Embryo Technology, Jan 2022, Savannah, GA, United States. , Reproduction, Fertility and Development, 34 (1-2), pp.261, 2022, Proceedings of the Annual Conference of the International Embryo Technology Society, Savannah, Georgia, 10–13 January 2022. ⟨10.1071/RDv34n2Ab52⟩
Poster de conférence
hal-03538184v1
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Dimorphisme sexuel chez les blastocystes équinsPoster de conférence hal-03469695v1 |
L'âge maternel modifie l'expression des gènes de l'embryonJournées sciences et innovations équines, Nov 2020, Jouy-en-Josas, France. 2020
Poster de conférence
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A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit modelJournée Aviesan, Jun 2019, Paris, France. , 2019, ITMO " Translational research on diabetic cardiomyopathy"
Poster de conférence
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Effects of maternal au-np exposure by inhalation on feto-placental development and placental function, in a rabbit modelIFPA 2019, Sep 2019, Buenos Aires, Argentina. , 135 p., 2019, IFPA 2019- VIII SLIMP Full Program Book
Poster de conférence
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A new culture model of rabbit trophoblastic cells to explore cell function and transplacental transfersAnnual Meeting 2018 CellFit, Oct 2018, Hvar Island, Croatia. School of Medicine University of Zagreb, Editors Tiziana Brevini, Alireza Fazeli, Ana Katusic, Ana Vidos, Georgia May, pp.109, 2018, Proceedings of CellFit Meeting 2018 « in vitro 3-D Total Cell Guidance and fitness »
Poster de conférence
hal-02738050v1
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A new culture model of rabbit trophoblastic cells to explore cell function and transplacental transfersPoster de conférence hal-02788443v1 |
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A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placentalphenotypein a rabbit modelIFPA 2018, Sep 2018, Tokyo, Japan. , Placenta, 9, pp.93, 2018, Abstracts for the forthcoming International Federation of Placenta Associations Meeting, Tokyo, Japan
Poster de conférence
hal-02734076v1
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Maternal exposure to diluted diesel engine exhaust alters placental function of the first and second generation in rabbit model8. International Symposium on Nanotechnology, Occupational and Environmental Health, May 2017, Elsinore, Denmark. , 147 p., 2017, 8th International Symposium on Nanotechnology, Occupational and Environmental Health
Poster de conférence
hal-01605995v1
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Détermination de la plus critique fenêtre d'exposition d'une surnutrition lipidique maternelle pour le développement foeto-placentaire: entre la période préconceptionnelle et la période gestationnelleJFN 2017, Journées Francophones de Nutrition, Dec 2017, Nantes, France. , pp.460, 2017, Livre des résumés Journées Francophones de Nutrition
Poster de conférence
hal-02735162v1
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystPoster de conférence hal-02741274v1 |
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystEpiconcept Conference 2016, Sep 2016, Giardini Naxos, Italy. COST Office, 84 p., 2016, Epigenetics and Periconception Environment
Poster de conférence
hal-02741142v1
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Tentative de démonstration de la pluripotence des cellules iPS de lapin par injection micro-échoguidée in vivo au stade péri-implantatoireJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase 2016), Apr 2016, Tours, France. , 115 p., 2016, Crédits Incitatifs financés entre 2011 et 2014
Poster de conférence
hal-02741331v1
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit modelXIV. International Congress of Toxicology, Oct 2016, Merida, Mexico. Elsevier Ireland Ltd, Toxicology Letters, 259, pp.269, 2016, Toxicology Letters. ⟨10.1016/j.toxlet.2016.07.100⟩
Poster de conférence
hal-01533918v1
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In utero exposure to diluted diesel engine exhaust alters placental function, fatty acids profiles and fetal metabolism of the second generation in rabbitsPoster de conférence hal-02741181v1 |
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The use of ultrasound biomicroscopy for embryo injectionsPoster de conférence hal-02741280v1 |
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The use of ultrasound biomicroscopy for embryo injectionsEpiconcept Conference 2015 - Epigenetics and Periconception Environment, Oct 2015, Hersonissos, Crete, Greece. Cost Office, 9, 2015, Epigenetics and Periconception Environment
Poster de conférence
hal-02741023v1
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Nulliparity affects the expression of a limited number of genes and pathways in Day 8 equine embryos2024
Pré-publication, Document de travail
hal-04446593v1
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Maternal parity affects Day 8 embryo gene expression in old mares2021
Pré-publication, Document de travail
hal-04446577v1
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230 Slight alterations of trophoblast gene expression are related to the term placenta morphology and gene expression in horsesInternational Embryo Technology Society (IETS), Reproduction, Fertility and Development, 35 (2), pp. 244-244, 2022, ⟨10.1071/RDv35n2Ab230⟩
Proceedings/Recueil des communications
hal-04444899v1
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