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Pascale Chavatte-Palmer

Pascale Chavatte-Palmer, INRAE Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort France
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Présentation

**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement** Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).

Publications

sophie-calderari

Effets d’un régime maternel hypergras sur le transcriptome ovocytaire et embryonnaire

Sophie Calderari , Catherine Archilla , Luc Jouneau , Nathalie Daniel , Nathalie N. Peynot
Société Francophone du Diabète, May 2022, Nice, France
Communication dans un congrès hal-03808248v1

Impact d’un environnement (pré)-diabétique sur le développement embryonnaire précoce

Sophie Calderari , Catherine Archilla , Luc Jouneau , Nathalie Daniel , Nathalie N. Peynot
SF-DOHAD, Nov 2021, Jouy-en-Josas, France
Communication dans un congrès hal-03808220v1
Image document

Effets de l’exposition maternelle aux nanoparticules d’or par ingestion, pendant la gestation, sur le développement foeto-placentaire et la fonction placentaire, dans un modèle lapin.

Camille Rousseau , Delphine Rousseau-Ralliard , Michèle Dahirel , Luc Jouneau , Josiane Aioun
7. Rencontre du Groupe de la Francophonie Placentaire 2019, Groupe de la francophonie Placentaire (GfP). FRA., Mar 2019, Paris, France. 36 p
Communication dans un congrès hal-02734084v1

Identification des voies fonctionnelles altérées par un régime maternal hypergras dans l’embryon pré-implantatoire de lapin

Sophie Calderari , Nathalie Daniel , Catherine Archilla , Eve Mourier , Christophe Richard
Journées d’Animation Scientifique du Département PHASE, Apr 2018, Rennes, France
Communication dans un congrès hal-02737130v1
Image document

Effets de l’exposition maternelle aux nanoparticules d’or par ingestion pendant la gestation, sur le développement foeto-placentaire et la fonction placentaire, dans un modèle lapin

Camille Rousseau , Delphine Rousseau-Ralliard , Michèle Dahirel , Christophe Richard , Luc Jouneau
4. Congrès de la SF-Dohad, Société Francophone-DOHaD. FRA., Nov 2018, Grenoble, France. pp.120
Communication dans un congrès hal-02734001v1

High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocyst

Sophie Calderari , Catherine Archilla , Luc Jouneau , Nathalie N. Peynot , Nathalie N. Daniel
Epiconcept Conference 2016, Sep 2016, Giardini Naxos, Italy. COST Office, 84 p., 2016, Epigenetics and Periconception Environment
Poster de conférence hal-02741142v1

High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocyst

Sophie Calderari , Catherine Archilla , Luc Jouneau , Nathalie Peynot , Nathalie Daniel
3. congrès de la SF-DOHaD, Dec 2016, Paris, France. , 84 p., 2016, 3ème congrès de la SF-DOHaD
Poster de conférence hal-02741274v1