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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
29%
Libre accès
28
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
Publications
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Effect of sex on gene expression in equine blastocysts.10th International Symposium on Equine Embryo Transfer and technology, University of Pisa, Jun 2022, Pise, Italy
Communication dans un congrès
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Effets d’un régime maternel hypergras sur le transcriptome ovocytaire et embryonnaireSociété Francophone du Diabète, May 2022, Nice, France
Communication dans un congrès
hal-03808248v1
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142 Nulliparity alters gene expression in inner cell mass and trophoblast of equine blastocysts in old mares47TH ANNUAL CONFERENCE OF THE IETS, Jan 2021, online, United States. pp.179, ⟨10.1071/RDv33n2Ab142⟩
Communication dans un congrès
hal-03153864v1
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Impact d’un environnement (pré)-diabétique sur le développement embryonnaire précoceSF-DOHAD, Nov 2021, Jouy-en-Josas, France
Communication dans un congrès
hal-03808220v1
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Mares’ age affects embryo ICM and trophoblast RNA-seq transcriptome at about D8International Symposium on Equine Embryo Transfer, Jul 2020, Pisa, Italy. pp.103031, ⟨10.1016/j.jevs.2020.103031⟩
Communication dans un congrès
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Identification des voies fonctionnelles altérées par un régime maternal hypergras dans l’embryon pré-implantatoire de lapinJournées d’Animation Scientifique du Département PHASE, Apr 2018, Rennes, France
Communication dans un congrès
hal-02737130v1
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit model18. International Congress on Animal Reproduction (ICAR), International Organisation on Animal Reproduction. FRA., Jun 2016, Tours, France. 676 p
Communication dans un congrès
hal-02740895v1
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit model3. congrès de la SF-DOHaD, Société Francophone pour la Recherche et l'Education sur les Origines Développementales, Environnementales et Epigénétiques de la Santé et des Maladies (SF-DOHAD). FRA., Dec 2016, Paris, France. 84 p
Communication dans un congrès
hal-02743432v1
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Maternal exposure to diesel engine exhaust during pregnancy affects early embryo development in a rabbit model41. Annual Conference of IETS, International Embryo Transfer Society (IETS). USA., Jan 2015, Versailles, France. ⟨10.1071/RDv27n1Ab120⟩
Communication dans un congrès
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Sexual dimorphism starting from the blastocyst stage in response to an imbalanced maternal diet in a rabbit modelMeeting of the International Federation of Placenta Associations (IFPA), Sep 2013, Whistler, British Columbia, Canada. ⟨10.1016/j.placenta.2013.06.054⟩
Communication dans un congrès
hal-01190599v1
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Hyperlipidic hypercholesterolemic maternal died affects early embryonic gene expression and trophoblast functionColloque SF-DOHaD, Société Francophone pour la Recherche et l'Education sur les Origines Développementales, Environnementales et Epigénétiques de la Santé et des Maladies (SF-DOHAD). FRA., Nov 2012, Paris, France
Communication dans un congrès
hal-02744786v1
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Analyses des conséquences de régimes hyperlipidiques administrés à la mère dans la période périconceptionnelle sur l'expression génique précoce de l'embryonJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase), Oct 2010, Tours, France. 1 p
Communication dans un congrès
hal-02820969v1
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Influence of a hyperlidic hypercholesterolemic diet on folliculogenesis and adipophlin expression in the preimplantation embryo in rabbitsProceeding of the 2nd General Meeting GEMINI: Maternal Communication with Gametes and Embryos, Oct 2009, Sardinia, Italy
Communication dans un congrès
hal-02756721v1
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Rabbit as a model for embryo development2. International Meeting on Rabbit Biotechnology, Jun 2007, Jouy en Josas, France. 1 p
Communication dans un congrès
hal-02823822v1
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Equine embryo size does matter!48th Annual Conference of the International Society of Embryo Technology, Jan 2022, Savannah, GA, United States. , Reproduction, Fertility and Development, 34 (1-2), pp.261, 2022, Proceedings of the Annual Conference of the International Embryo Technology Society, Savannah, Georgia, 10–13 January 2022. ⟨10.1071/RDv34n2Ab52⟩
Poster de conférence
hal-03538184v1
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Dimorphisme sexuel chez les blastocystes équinsPoster de conférence hal-03469695v1 |
L'âge maternel modifie l'expression des gènes de l'embryonJournées sciences et innovations équines, Nov 2020, Jouy-en-Josas, France. 2020
Poster de conférence
hal-03290867v1
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystEpiconcept Conference 2016, Sep 2016, Giardini Naxos, Italy. COST Office, 84 p., 2016, Epigenetics and Periconception Environment
Poster de conférence
hal-02741142v1
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystPoster de conférence hal-02741274v1 |
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit modelXIV. International Congress of Toxicology, Oct 2016, Merida, Mexico. Elsevier Ireland Ltd, Toxicology Letters, 259, pp.269, 2016, Toxicology Letters. ⟨10.1016/j.toxlet.2016.07.100⟩
Poster de conférence
hal-01533918v1
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Nulliparity affects the expression of a limited number of genes and pathways in Day 8 equine embryos2024
Pré-publication, Document de travail
hal-04446593v1
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