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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
36%
Libre accès
39
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
Publications
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Effets d’un régime maternel hypergras sur le transcriptome ovocytaire et embryonnaireSociété Francophone du Diabète, May 2022, Nice, France
Communication dans un congrès
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Effect of sex on gene expression in equine blastocysts.10th International Symposium on Equine Embryo Transfer and technology, University of Pisa, Jun 2022, Pise, Italy
Communication dans un congrès
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142 Nulliparity alters gene expression in inner cell mass and trophoblast of equine blastocysts in old mares47TH ANNUAL CONFERENCE OF THE IETS, Jan 2021, online, United States. pp.179, ⟨10.1071/RDv33n2Ab142⟩
Communication dans un congrès
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Impact d’un environnement (pré)-diabétique sur le développement embryonnaire précoceSF-DOHAD, Nov 2021, Jouy-en-Josas, France
Communication dans un congrès
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Mares’ age affects embryo ICM and trophoblast RNA-seq transcriptome at about D8International Symposium on Equine Embryo Transfer, Jul 2020, Pisa, Italy. pp.103031, ⟨10.1016/j.jevs.2020.103031⟩
Communication dans un congrès
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Identification des voies fonctionnelles altérées par un régime maternal hypergras dans l’embryon pré-implantatoire de lapinJournées d’Animation Scientifique du Département PHASE, Apr 2018, Rennes, France
Communication dans un congrès
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Détermination de la fenêtre de vulnérabilité à une surnutrition lipidique maternelle pour le développement foeto-placentaire: période pré-conceptionnelle et/ou période gestationnelle?4. Congrès de la SF-Dohad, Société Francophone-DOHaD. FRA., Nov 2018, Grenoble, France. pp.120
Communication dans un congrès
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Analyse des échanges transplacentaires par perfusion placentaire ex-vivo ou par des modèles cellulaires in vitroJournées d'Animation Scientifique du Département PHASE, Apr 2018, Rennes, France
Communication dans un congrès
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit model3. congrès de la SF-DOHaD, Société Francophone pour la Recherche et l'Education sur les Origines Développementales, Environnementales et Epigénétiques de la Santé et des Maladies (SF-DOHAD). FRA., Dec 2016, Paris, France. 84 p
Communication dans un congrès
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit model18. International Congress on Animal Reproduction (ICAR), International Organisation on Animal Reproduction. FRA., Jun 2016, Tours, France. 676 p
Communication dans un congrès
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Maternal exposure to diesel engine exhaust during pregnancy affects early embryo development in a rabbit model41. Annual Conference of IETS, International Embryo Transfer Society (IETS). USA., Jan 2015, Versailles, France. ⟨10.1071/RDv27n1Ab120⟩
Communication dans un congrès
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A short periconceptional maternal hyperglycemia is sufficient to disrupt the feto-placental phenotype in a rabbit model41. Annual Conference of IETS, International Embryo Transfer Society (IETS). USA., Jan 2015, Versailles, France. ⟨10.1071/RDv27n1Ab119⟩
Communication dans un congrès
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A short periconceptional maternal hyperglycemia is sufficient to disrupt the feto-placental phenotype in a rabbit model2. Colloque de la SF-DOHaD, Origine Développementale de la santé et des maladies et épigénétique, Société Francophone pour la Recherche et l'Education sur les Origines Développementales, Environnementales et Epigénétiques de la Santé et des Maladies (SF-DOHAD). FRA., Nov 2014, Nantes, France. 57 p
Communication dans un congrès
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Generation of a cloned green fluorescent protein (GFP) expressing transgenic sheep for muscle stem cell graft experiments37. Annual Conference of the IETS, International Embryo Transfer Society (IETS). USA., Jan 2011, Orlando, United States. pp.259, ⟨10.1071/RDv23n1Ab325⟩
Communication dans un congrès
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Rabbit as a model for embryo development2. International Meeting on Rabbit Biotechnology, Jun 2007, Jouy en Josas, France. 1 p
Communication dans un congrès
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Equine embryo size does matter!48th Annual Conference of the International Society of Embryo Technology, Jan 2022, Savannah, GA, United States. , Reproduction, Fertility and Development, 34 (1-2), pp.261, 2022, Proceedings of the Annual Conference of the International Embryo Technology Society, Savannah, Georgia, 10–13 January 2022. ⟨10.1071/RDv34n2Ab52⟩
Poster de conférence
hal-03538184v1
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L'âge maternel modifie l'expression des gènes de l'embryonJournées sciences et innovations équines, Nov 2020, Jouy-en-Josas, France. 2020
Poster de conférence
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A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit modelJournée Aviesan, Jun 2019, Paris, France. , 2019, ITMO " Translational research on diabetic cardiomyopathy"
Poster de conférence
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A new culture model of rabbit trophoblastic cells to explore cell function and transplacental transfersAnnual Meeting 2018 CellFit, Oct 2018, Hvar Island, Croatia. School of Medicine University of Zagreb, Editors Tiziana Brevini, Alireza Fazeli, Ana Katusic, Ana Vidos, Georgia May, pp.109, 2018, Proceedings of CellFit Meeting 2018 « in vitro 3-D Total Cell Guidance and fitness »
Poster de conférence
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A new culture model of rabbit trophoblastic cells to explore cell function and transplacental transfersPoster de conférence hal-02788443v1 |
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A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placentalphenotypein a rabbit modelIFPA 2018, Sep 2018, Tokyo, Japan. , Placenta, 9, pp.93, 2018, Abstracts for the forthcoming International Federation of Placenta Associations Meeting, Tokyo, Japan
Poster de conférence
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Détermination de la plus critique fenêtre d'exposition d'une surnutrition lipidique maternelle pour le développement foeto-placentaire: entre la période préconceptionnelle et la période gestationnelleJFN 2017, Journées Francophones de Nutrition, Dec 2017, Nantes, France. , pp.460, 2017, Livre des résumés Journées Francophones de Nutrition
Poster de conférence
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystEpiconcept Conference 2016, Sep 2016, Giardini Naxos, Italy. COST Office, 84 p., 2016, Epigenetics and Periconception Environment
Poster de conférence
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The use of ultrasound biomicroscopy for embryo injectionsPoster de conférence hal-02741280v1 |
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Tentative de démonstration de la pluripotence des cellules iPS de lapin par injection micro-échoguidée in vivo au stade péri-implantatoireJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase 2016), Apr 2016, Tours, France. , 115 p., 2016, Crédits Incitatifs financés entre 2011 et 2014
Poster de conférence
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit modelXIV. International Congress of Toxicology, Oct 2016, Merida, Mexico. Elsevier Ireland Ltd, Toxicology Letters, 259, pp.269, 2016, Toxicology Letters. ⟨10.1016/j.toxlet.2016.07.100⟩
Poster de conférence
hal-01533918v1
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystPoster de conférence hal-02741274v1 |
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The use of ultrasound biomicroscopy for embryo injectionsEpiconcept Conference 2015 - Epigenetics and Periconception Environment, Oct 2015, Hersonissos, Crete, Greece. Cost Office, 9, 2015, Epigenetics and Periconception Environment
Poster de conférence
hal-02741023v1
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Maternal parity affects Day 8 embryo gene expression in old mares2021
Pré-publication, Document de travail
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