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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
22%
Libre accès
23
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit model18. International Congress on Animal Reproduction (ICAR), International Organisation on Animal Reproduction. FRA., Jun 2016, Tours, France. 676 p
Communication dans un congrès
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Maternal exposure to diesel exhaust alters placental function and induces intergenerational effects in rabbits44. Annual Conference of the European Teratology Society, European Teratology Society (ETS). GBR., Sep 2016, Dublin, Ireland. 210 p., ⟨10.1016/j.reprotox.2016.06.054⟩
Communication dans un congrès
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit model3. congrès de la SF-DOHaD, Société Francophone pour la Recherche et l'Education sur les Origines Développementales, Environnementales et Epigénétiques de la Santé et des Maladies (SF-DOHAD). FRA., Dec 2016, Paris, France. 84 p
Communication dans un congrès
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Diet around puberty and mammary gland development in the rabbitCOST RGB TD1101 Meeting, Mar 2012, Bologne, Italy. 13 diapositives
Communication dans un congrès
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Effet de l'adiposité sur le développement de la glande mammaire2.Congrès de Médecine périconceptionnelle - In utero, Association Française de Pédiatrie Ambulatoire (AFPA). FRA., Oct 2012, Paris, France. pp.6
Communication dans un congrès
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Diet-induced adiposity leads to early mammary gland development during pregnancy in the rabbit4. International Rabbit Biotechnology Meeting, Jun 2011, Budapest, Hungary. 1 p
Communication dans un congrès
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Effets du régime alimentaire sur le développement de la glande mammaire et la qualité de l'allaitement14. Journées de la Recherche Cunicole, Nov 2011, Le Mans, France. pp.49-52
Communication dans un congrès
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Long-term effects of nutrition on mammary gland development and milk composition leading to offspring predisposition to obesity8. International Symposium on Milk Genomics & Human Health, Nov 2011, Melbourne, Australia. 1 p
Communication dans un congrès
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Nutrition at puberty and mammary gland development2. International Symposium on Breast Cancer Prevention, Oct 2011, Rennes, France
Communication dans un congrès
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Rôle de l’état d’adiposité sur le développement de la glande mammaire chez le lapinJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase), Oct 2010, Tours, France
Communication dans un congrès
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Placental expression of leptin and neonatal plasma concentrations in horses and ponies61. Annual Meeting of the European Association for Animal Production, Aug 2010, Heraklion, Greece
Communication dans un congrès
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Analyse des fonctions biologiques de l'OPL par transfection transitoire d'ARNI in vivo : développement des approches et résultats préliminairesJournées de Restitution des Projets financés sur Crédits Incitatifs en 2006 et 2007 - Département de Physiologie Animale et Système d'Elevage, Nov 2008, Tours, France
Communication dans un congrès
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Effets d’une exposition maternelle aux nanoparticules diesel sur le développement de la glande mammaire et la lactation4. Congrès de la SF-Dohad, Nov 2018, Grenoble, France. , pp.120, 2018, Proceedings du 4ème congrès de la SF-DOHaD
Poster de conférence
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit modelXIV. International Congress of Toxicology, Oct 2016, Merida, Mexico. Elsevier Ireland Ltd, Toxicology Letters, 259, pp.269, 2016, Toxicology Letters. ⟨10.1016/j.toxlet.2016.07.100⟩
Poster de conférence
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In utero diesel exhaust exposure induces altered placenta vascularization, placental nanoparticles transfer and intergenerational effects55. Annual Meeting and ToxExpo, Mar 2016, New Orléans, Louisiane, United States. , Toxicological Sciences, 150 (S1), 384 p., 2016, Toxicological Sciences
Poster de conférence
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Effets à long terme de l’adiposité sur la qualité du lait et le développement de la glande mammaire de la descendance12. Journées Francophones de Nutrition, Dec 2014, Bruxelles, Belgique. Elsevier Mason SAS, Nutrition Clinique et Métabolisme, 28 (S1), 240 p., 2014, 12èmes Journées Francophones de Nutrition, JFN 2014. ⟨10.1016/S0985-0562(14)70805-2⟩
Poster de conférence
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Role of leptin in milk for development programming using a rabbit modelGEMINI Group III Workshop, May 2011, Jerusalem, Israel. Cost Office, pp.65, 2011, GEMINI Periconceptional Developmental Programming
Poster de conférence
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Diet-induced obesity leads to early mammary gland development during pregnancy in the rabbit6. International Symposium Milk Genomics & Human Health, Sep 2009, Paris, France. n.p., 2009
Poster de conférence
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