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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
56%
Libre accès
18
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
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Equine blastocyst size affects gene expressionJournal of Equine Veterinary Science, 2022, 113 (27), pp.103982. ⟨10.1016/j.jevs.2022.103982⟩
Article dans une revue
hal-03703215v1
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Maternal age affects equine day 8 embryo gene expression both in trophoblast and inner cell massBMC Genomics, 2022, 23 (1), pp.443. ⟨10.1186/s12864-022-08593-7⟩
Article dans une revue
hal-03695686v2
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Effect of sex on gene expression in equine blastocystsJournal of Equine Veterinary Science, 2022, 113 (25), pp.103980. ⟨10.1016/j.jevs.2022.103980⟩
Article dans une revue
hal-03703063v1
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105 Sexual dimorphism in equine D8 blastocysts (abstract)Journal of Equine Veterinary Science, 2021, 100, pp.103568. ⟨10.1016/j.jevs.2021.103568⟩
Article dans une revue
hal-03288513v1
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Effect of sex on gene expression in equine blastocysts.10th International Symposium on Equine Embryo Transfer and technology, University of Pisa, Jun 2022, Pise, Italy
Communication dans un congrès
hal-03716812v1
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Nursing in the periconceptional period alters placental gene expression and subsequent foal growth18th European Placenta Group IFPA meeting, European Placenta Group, Nov 2022, Jouy en Josas, France
Communication dans un congrès
hal-03903205v1
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142 Nulliparity alters gene expression in inner cell mass and trophoblast of equine blastocysts in old mares47TH ANNUAL CONFERENCE OF THE IETS, Jan 2021, online, United States. pp.179, ⟨10.1071/RDv33n2Ab142⟩
Communication dans un congrès
hal-03153864v1
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Mares’ age affects embryo ICM and trophoblast RNA-seq transcriptome at about D8International Symposium on Equine Embryo Transfer, Jul 2020, Pisa, Italy. pp.103031, ⟨10.1016/j.jevs.2020.103031⟩
Communication dans un congrès
hal-03029288v1
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Proteomic, metabolomic and fatty acid composition in lactating and non-lactating mares’ uterine fluids46th IETS conference, Jan 2020, New York, United States. ⟨10.1071/RDv32n2abs⟩
Communication dans un congrès
hal-02454910v1
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Placental gene expression reveals reduced angiogenesis in primiparous maresXIIth International Symposium on Equine Reproduction (ISER), Jul 2023, Fos do Iguaçu, Brazil. Journal of equine veterinary science, 125, pp.104763, 2023, ⟨10.1016/j.jevs.2023.104763⟩
Poster de conférence
hal-04147559v1
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Equine embryo size does matter!48th Annual Conference of the International Society of Embryo Technology, Jan 2022, Savannah, GA, United States. , Reproduction, Fertility and Development, 34 (1-2), pp.261, 2022, Proceedings of the Annual Conference of the International Embryo Technology Society, Savannah, Georgia, 10–13 January 2022. ⟨10.1071/RDv34n2Ab52⟩
Poster de conférence
hal-03538184v1
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NURSING IN THE PERICONCEPTIONAL PERIOD ALTERS PLACENTAL GENE EXPRESSION AND SUBSEQUENT FOAL GROWTHPoster de conférence hal-03793660v1 |
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Maternal age alters gene expression in blastocyst trophoblast and term placenta as well as term placental structurePoster de conférence hal-03348714v1 |
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Dimorphisme sexuel chez les blastocystes équinsPoster de conférence hal-03469695v1 |
L'âge maternel modifie l'expression des gènes de l'embryonJournées sciences et innovations équines, Nov 2020, Jouy-en-Josas, France. 2020
Poster de conférence
hal-03290867v1
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Nulliparity affects the expression of a limited number of genes and pathways in Day 8 equine embryos2024
Pré-publication, Document de travail
hal-04446593v1
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Maternal parity affects Day 8 embryo gene expression in old mares2021
Pré-publication, Document de travail
hal-04446577v1
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230 Slight alterations of trophoblast gene expression are related to the term placenta morphology and gene expression in horsesInternational Embryo Technology Society (IETS), Reproduction, Fertility and Development, 35 (2), pp. 244-244, 2022, ⟨10.1071/RDv35n2Ab230⟩
Proceedings/Recueil des communications
hal-04444899v1
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