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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
18%
Libre accès
11
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
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Impact of exposure to diesel exhaust during pregnancy on mammary gland development and milk composition in the rabbitPLoS ONE, 2019, 14 (2), pp.1-18. ⟨10.1371/journal.pone.0212132⟩
Article dans une revue
hal-02050122v1
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An Obesogenic Diet Started Before Puberty Leads to Abnormal Mammary Gland Development During Pregnancy in the RabbitDevelopmental Dynamics, 2011, 240 (2), pp.347-356. ⟨10.1002/dvdy.22536⟩
Article dans une revue
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Effets du régime alimentaire sur le développement de la glande mammaire et la qualité de l'allaitement14. Journées de la Recherche Cunicole, Nov 2011, Le Mans, France. pp.49-52
Communication dans un congrès
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Diet-induced adiposity leads to early mammary gland development during pregnancy in the rabbit4. International Rabbit Biotechnology Meeting, Jun 2011, Budapest, Hungary. 1 p
Communication dans un congrès
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Long-term effects of nutrition on mammary gland development and milk composition leading to offspring predisposition to obesity8. International Symposium on Milk Genomics & Human Health, Nov 2011, Melbourne, Australia. 1 p
Communication dans un congrès
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Nutrition at puberty and mammary gland development2. International Symposium on Breast Cancer Prevention, Oct 2011, Rennes, France
Communication dans un congrès
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Rôle de l’état d’adiposité sur le développement de la glande mammaire chez le lapinJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase), Oct 2010, Tours, France
Communication dans un congrès
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Transgenerational effects of a maternal hyperlipidic hypercholesterolemic diet on the morphology of placentas, in a rabbit modelThe Perinatal Determinants of Adult Health and Disease & 13. International Symposium on Perinatal Nephrology: "Early Determinants of Renal Function & Disease at Adulthood, Jun 2010, Marseille, France
Communication dans un congrès
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Transgenerational effects of a maternal hyperlipidic hypercholesterolemic diet on the morphology of placentas, in a rabbit model3. General Meeting of Gemini: Maternal Communication with Gametes and Embryos, Oct 2010, Soustons, France
Communication dans un congrès
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Effets à long terme de l’adiposité sur la qualité du lait et le développement de la glande mammaire de la descendance12. Journées Francophones de Nutrition, Dec 2014, Bruxelles, Belgique. Elsevier Mason SAS, Nutrition Clinique et Métabolisme, 28 (S1), 240 p., 2014, 12èmes Journées Francophones de Nutrition, JFN 2014. ⟨10.1016/S0985-0562(14)70805-2⟩
Poster de conférence
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Diet-induced obesity leads to early mammary gland development during pregnancy in the rabbit6. International Symposium Milk Genomics & Human Health, Sep 2009, Paris, France. n.p., 2009
Poster de conférence
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