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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
27%
Libre accès
26
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
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Effects of maternal au-np exposure by inhalation on feto-placental development and placental function, in a rabbit modelIFPA 2019, Sep 2019, Buenos Aires, Argentina. , 135 p., 2019, IFPA 2019- VIII SLIMP Full Program Book
Poster de conférence
hal-02733979v1
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La supplémentation en céréales en fin de gestation perturbe la fonction placentaire chez la jument6. Colloque International du Groupe de la Francophonie Placentaire, Sep 2017, Grenoble, France. , 47 p., 2017, Sixième Colloque International du Groupe de la Francophonie Placentaire "De l'implantation à la parturition: Bases fondamentales et cliniques"
Poster de conférence
hal-01607380v1
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Maternal exposure to diluted diesel engine exhaust alters placental function of the first and second generation in rabbit model8. International Symposium on Nanotechnology, Occupational and Environmental Health, May 2017, Elsinore, Denmark. , 147 p., 2017, 8th International Symposium on Nanotechnology, Occupational and Environmental Health
Poster de conférence
hal-01605995v1
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystEpiconcept Conference 2016, Sep 2016, Giardini Naxos, Italy. COST Office, 84 p., 2016, Epigenetics and Periconception Environment
Poster de conférence
hal-02741142v1
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High fat maternal diet impacts the nutrient sensing signaling network in rabbit blastocystPoster de conférence hal-02741274v1 |
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The mare’s placenta is able to adapt to moderate maternal undernutrition during late gestation to sustain fetal growth18. International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. , 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR)
Poster de conférence
hal-02742103v1
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In utero exposure to diluted diesel engine exhaust alters placental function, fatty acids profiles and fetal metabolism of the second generation in rabbitsPoster de conférence hal-02741181v1 |
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Reproductive effects of gestational exposure to diesel exhaust in a rabbit modelXIV. International Congress of Toxicology, Oct 2016, Merida, Mexico. Elsevier Ireland Ltd, Toxicology Letters, 259, pp.269, 2016, Toxicology Letters. ⟨10.1016/j.toxlet.2016.07.100⟩
Poster de conférence
hal-01533918v1
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Studying the placental rabbit methylome and its alteration in intrauterine growth restriction (IUGR) cases during gestationConférence Jacques Monod, DNA methylation and demethylation, Nov 2015, Roscoff, France. , 2015, Conférence Jacques Monod, DNA methylation and demethylation
Poster de conférence
hal-02741269v1
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Developing a toolbox to study the rabbit methylome and its alteration in IUGR cases during gestationConference 2014 Epiconcept "Epigenetics and Periconception Environment", Oct 2014, Vilamoura, Portugal. COST Office European Cooperation in Science and Technology, 72 p., 2014, Epigenetics and Periconception Environment
Poster de conférence
hal-02741118v1
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