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Tau Regulates Glioblastoma Progression, 3D Cell Organization, Growth and Migration via the PI3K-AKT Axis

Alessandra Pagano , Gilles Breuzard , Fabrice Parat , Aurelie Tchoghandjian , Dominique Figarella‑branger , et al.
Cancers, 2021, 13 (22), pp.5818. ⟨10.3390/cancers13225818⟩
Article dans une revue hal-03470226v1
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Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation- dependent mechanism

Sacnicte Ramirez-Rios , Eric Denarier , Elea Prezel , Angélique Vinit , Virginie Stoppin-Mellet , et al.
Molecular Biology of the Cell, 2016, 27 (19), pp.2924-2934. ⟨10.1091/mbc.E16-01-0029)⟩
Article dans une revue hal-01478521v1
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Theoretical studies of the ground state and of the spectroscopic properties of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate analogs

M Sarrazin , Pascale Barbier , C Briand , V Peyrot
Journal of Molecular Structure: THEOCHEM, 2001, 541 (1-3), pp.253-262. ⟨10.1016/S0166-1280(00)00809-5⟩
Article dans une revue hal-01480677v1
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Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics

Badreddine Douzi , Nhung Trinh , Sandra Michel-Souzy , Aline Desmyter , Genevieve Ball , et al.
mBio, 2017, 8 (5), ⟨10.1128/mBio.01185-17⟩
Article dans une revue hal-01744494v1
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2-Aminothiazole-Flavonoid Hybrid Derivatives Binding to Tau Protein and Responsible for Antitumor Activity in Glioblastoma

Rayane Hedna , Attilio Dimaio , Maxime Robin , Diane Allegro , Mario Tatoni , et al.
International Journal of Molecular Sciences, 2023, 24 (20), pp.15050. ⟨10.3390/ijms242015050⟩
Article dans une revue hal-04281487v1

Synthesis and complete assignment of the 1H and 13C NMR signals of new acetamido and aminoflavonoid derivatives

Gilles Casano , Maxime Robin , Pascale Barbier , Vincent Peyrot , Robert Faure
Magnetic Resonance in Chemistry, 2010, 48 (9), pp.738 - 744. ⟨10.1002/mrc.2638⟩
Article dans une revue istex hal-01753144v1
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Direct evidence for the interaction of stathmin along the length and the plus end of microtubules in cells

Roqiya Nouar , Gilles Breuzard , Sonia Bastonero , Svetlana Gorokhova , Pascale Barbier , et al.
FASEB Journal, 2016, 30 (9), pp.3202 - 3215. ⟨10.1096/fj.201500125R⟩
Article dans une revue inserm-01472736v1

Hsp90 Oligomers Interacting with the Aha1 Cochaperone: An Outlook for the Hsp90 Chaperone Machineries

Eléonore Lepvrier , Laura Moullintraffort , Michaël Nigen , Renan Goude , Diane Allegro , et al.
Analytical Chemistry, 2015, 87 (14), pp.7043-7051. ⟨10.1021/acs.analchem.5b00051⟩
Article dans une revue hal-01175535v1
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Microtubule and MAPs: thermodynamics of complex formation by AUC, ITC, fluorescence, and NMR.

François Devred , Pascale Barbier , Daniel Lafitte , Isabelle Landrieu , Guy Lippens , et al.
Methods in Cell Biology, 2010, 95, pp.449-480. ⟨10.1016/S0091-679X(10)95023-1⟩
Article dans une revue hal-00508818v1

Tau aggregation in Alzheimer's disease : what role for phosphorylation ?

Guy Lippens , Alain Sillen , Isabelle Landrieu , Laziza Amniai , Nathalie Sibille , et al.
Prion, 2007, 1 (1), pp.21-25
Article dans une revue hal-00161158v1
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Microtubule-Associated Proteins and Tubulin Interaction by Isothermal Titration Calorimetry

Philipp O Tsvetkov , Pascale Barbier , Gilles Breuzard , Vincent Peyrot , François Devred
Methods in Cell Biology, 115, pp.283 - 302, 2013, Microtubules, In Vitro 978-0-12-407757-7. ⟨10.1016/B978-0-12-407757-7.00018-9⟩
Chapitre d'ouvrage hal-01478645v1
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Self-assembly of XcpQ secretin N domain into hexamer of dimers provides new molecular insights into architecture and dynamics of widespread outer membrane channels

Badreddine Douzi , Romé Voulhoux , - Nhung. T. T. Trinh , - Sandra Michel-Souzy , Aline Desmyter , et al.
New Approaches and Concepts in Microbiology, Jun 2017, Heidelberg, Germany. , 2017
Poster de conférence hal-02737898v1

Caulerpenyne binding to tubulin: structural modifications by a non conventional pharmacological agent.

Julien Bourdron , Pascale Barbier , Diane Allegro , Claude Villard , Daniel Lafitte , et al.
Medicinal Chemistry, 2009, 5 (2), pp.182-90
Article dans une revue hal-00678950v1

Molecular mechanisms of Tau binding to microtubules and its role in microtubule dynamics in live cells.

Gilles Breuzard , Pierre Hubert , Roqiya Nouar , Tiphany De Bessa , François Devred , et al.
Journal of Cell Science, 2013, 126 (Pt 13), pp.2810--9. ⟨10.1242/jcs.120832⟩
Article dans une revue hal-01458234v1
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Tau Interaction with Tubulin and Microtubules: From Purified Proteins to Cells

Tiphany de Bessa , Gilles Breuzard , Diane Allegro , François Devred , Vincent Peyrot , et al.
Tau Protein, 1523, pp.61-85, 2017, ⟨10.1007/978-1-4939-6598-4_4⟩
Chapitre d'ouvrage hal-01744157v2
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Tau Induces Ring and Microtubule Formation from R-Tubulin Dimers under Nonassembly Conditions

François Devred , Pascale Barbier , Soazig Douillard , Octavio Monasterio , José Manuel Andreu , et al.
Biochemistry, 2004, 43 (32), pp.10520-10531. ⟨10.1021/bi0493160⟩
Article dans une revue hal-01340743v1

Insights into the coiled-coil organization of the Hendra virus phosphoprotein from combined biochemical and SAXS studies

Matilde Beltrandi , David Blocquel , Jenny Erales , Pascale Barbier , Andrea Cavalli , et al.
Virology, 2015, 477, pp.42-55. ⟨10.1016/j.virol.2014.12.029⟩
Article dans une revue hal-01439015v1

Apo-Hsp90 coexists in two open conformational states in solution.

Patrick Bron , Emmanuel Giudice , Jean-Paul Rolland , Rubén M Buey , Pascale Barbier , et al.
Biology of the Cell, 2008, 100 (7), pp.413-25. ⟨10.1042/BC20070149⟩
Article dans une revue hal-00290075v1

Hsp90 Oligomerization Process: How Can p23 Drive the Chaperone Machineries?

Eléonore Lepvrier , Michaël Nigen , Laura Moullintraffort , Sophie Chat , Diane Allegro , et al.
Biochimica et Biophysica Acta Proteins and Proteomics, 2015, 1854 (10), pp.1412-1424. ⟨10.1016/j.bbapap.2015.07.003⟩
Article dans une revue hal-01174219v1
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Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat.

Caroline Egelé , Pascale Barbier , Pascal Didier , Etienne Piémont , Diane Allegro , et al.
Retrovirology, 2008, 5, pp.62. ⟨10.1186/1742-4690-5-62⟩
Article dans une revue hal-00321631v1

Allocolchicinoids bearing a Michael acceptor fragment for possible irreversible binding of tubulin

Ekaterina Sazanova , Iuliia Gracheva , Diane Allegro , Pascale Barbier , Sébastien Combes , et al.
RSC Medicinal Chemistry, 2020, 11 (6), pp.696-706. ⟨10.1039/D0MD00060D⟩
Article dans une revue hal-02997624v1

The Indolylcoumarin Coufin Exhibits Potent Activity Against Renal Carcinoma Cells without Affecting Hematopoietic System.

Pierre Champelovier , Pascale Barbier , Etienne Daras , Soazig Douillard , Bertrand Toussaint , et al.
Current Medicinal Chemistry Anticancer Agents, 2014, epub ahead of print. ⟨10.2174/1871520614666140223190829⟩
Article dans une revue hal-01005896v1
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Deciphering the molecular mechanisms of anti-tubulin plant derived drugs

Pascale Barbier , Philipp O. Tsvetkov , Gilles Breuzard , François Devred
Phytochemistry Reviews, 2014, 13 (1), pp.157-169. ⟨10.1007/s11101-013-9302-8⟩
Article dans une revue hal-01470519v1
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Quantitative Analysis of Tau-Microtubule Interaction Using FRET

Isabelle L. Di Maio , Pascale Barbier , Diane Allegro , Cédric Brault , Vincent Peyrot
International Journal of Molecular Sciences, 2014, 15 (8), pp.14697-14714. ⟨10.3390/ijms150814697⟩
Article dans une revue hal-01314628v1
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Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

Francois Iv , Carla Silva Martins , Gerard Castro-Linares , Cyntia Taveneau , Pascale Barbier , et al.
Journal of Cell Science, 2021, 134 (15), pp.jcs258484. ⟨10.1242/jcs.258484⟩
Article dans une revue hal-03119193v1

Synthesis and Biological Evaluation of Furanoallocolchicinoids

Yuliya Voitovich , Ekaterina Shegravina , Nikolay Sitnikov , Vladimir Faerman , Valery Fokin , et al.
Journal of Medicinal Chemistry, 2014, 58 (2), pp.692 - 704. ⟨10.1021/jm501678w⟩
Article dans une revue hal-01744566v1
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Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges

Marlène Martinho , Diane Allegro , Isabelle Huvent , Charlotte Chabaud , Emilien Etienne , et al.
Scientific Reports, 2018, 8 (1), pp.13846. ⟨10.1038/s41598-018-32096-9⟩
Article dans une revue hal-01883844v1

NMR Investigation of the Interaction between the Neuronal Protein Tau and the Microtubules.

Alain Sillen , Pascale Barbier , Isabelle Landrieu , Sylvie Lefebvre , Jean-Michel Wieruszeski , et al.
Biochemistry, 2007, 46 (11), pp.3055-3064. ⟨10.1021/bi061920i⟩
Article dans une revue istex hal-00139673v1

Interactions of long-chain homologues of colchicine with tubulin

Ana Marzo-Mas , Pascale Barbier , Gilles Breuzard , Diane Allegro , Eva Falomir , et al.
European Journal of Medicinal Chemistry, 2017, 126, pp.526 - 535. ⟨10.1016/j.ejmech.2016.11.049⟩
Article dans une revue hal-01744468v1
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Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

Pascale Barbier , Orgeta Zejneli , Marlène Martinho , Alessia Lasorsa , Valérie Belle , et al.
Frontiers in Aging Neuroscience, 2019, 11, ⟨10.3389/fnagi.2019.00204⟩
Article dans une revue hal-02279660v1