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43

Sanders Pascal


 

SANDERS Pascal

 

5, rue des Artisans

 

35133 JAVENE

 

56 ans, marié, 3 enfants.

 

 

 

Directeur du Laboratoire de Fougères

 

Agence Nationale de Sécurité Sanitaire, Alimentation, Environnement Travail

 

 

 

DIPLOMES

 

2000

Diplomate of the European College of Veterinary Pharmacology and Toxicology (Dip.ECVPT)

European Board of Veterinary Specialisation

1997

Habilitation à Diriger des Recherches

 

Institut National Polytechnique de Toulouse

1992

Doctorat de l'Institut National Polytechnique de Toulouse

 

Spécialité : Production animale et Qualité des denrées.

 

Lauréat du prix de thèse Léopold Escande 1993

1989

DEA Traitement des données statistiques

 

Suivi des cours et attestation d’études approfondies.

 

Faculté de Rennes

1986

Certificat de statistique appliquée à la médecine

 

Option Recherche Clinique

 

Institut de Statistique des Universités de Paris.

1985

Doctorat Vétérinaire

 

Faculté de Médecine de Toulouse

 

 

 

EXPERIENCE PROFESSIONNELLE

 

 

 

Depuis Août 2017

Directeur Scientifique « Exposition-Toxicologie »
Direction Stratégie et programmation.

Depuis Mai 1999

Directeur du Laboratoire

 

Responsable hiérarchique des unités de recherches et des services du laboratoire.

 

 

1996-1999

Chef du Département “ Médicament Vétérinaire ”

 

Animation scientifique et technique de 3 unités de recherches et d’appui scientifique et technique. Membre de la Direction Générale du CNEVA

 

 

1989-1997

Chef de l'unité de Pharmacocinétique

 

Travaux de recherches en bioanalytique et pharmacocinétique. Contrôle de la partie efficacité des dossiers d'AMM

 

 

1985-1989.

Attaché de Recherches

Travaux de recherches en bioanalytique et pharmacocinétique. Contrôle de la partie efficacité des dossiers d'AMM

 

 

 


Journal articles33 documents

  • Pascal Sanders, Claire Chauvin. Premiers résultats du programme de recherches "EFFORT: Ecology from farm to fork of antimicrobial resistance transmission". Bulletin des G.T.V., 2019, pp.14-14. ⟨anses-02305850⟩
  • Philip Joosten, Steven Sarrazin, Liese van Gompel, Roosmarijn Luiken, Jaap Wagenaar, et al.. Quantitative and qualitative analysis of antimicrobial usage at farm and flock level on 181 broiler farms in nine European countries. Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (3), pp.798-806. ⟨10.1093/jac/dky498⟩. ⟨anses-02335839⟩
  • Roosmarijn Luiken, Liese van Gompel, Patrick Munk, Steven Sarrazin, Philip Joosten, et al.. Associations between antimicrobial use and the faecal resistome on broiler farms from nine European countries. Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (9), pp.2596-2604. ⟨10.1093/jac/dkz235⟩. ⟨anses-02335763⟩
  • S.E.P Mensah, H. Dakpogan, A. B. Aboh, K. Chabi Sika, M. Abléto, et al.. Occurrence of antibiotic residues in raw fish Clarias gariepinus and Oreochromis niloticus from intensive rearing system in Benin. Veterinaria, Veterinary Faculty Sarajevo, 2019, 68 (2), pp.91-94. ⟨anses-02336074⟩
  • Patrick Munk, Berith Elkær Knudsen, Oksana Lukjancenko, Ana Sofia Ribeiro Duarte, Liese van Gompel, et al.. Abundance and diversity of the faecal resistome in slaughter pigs and broilers in nine European countries. Nature Microbiology, Nature Publishing Group, 2018, 3 (8), pp.898 - 908. ⟨10.1038/s41564-018-0192-9⟩. ⟨anses-01873810⟩
  • Jérôme Henri, Anne-Marie Jacques, Pascal Sanders, Anne Chevance, Michel Laurentie. The present and future of withdrawal period calculations for milk in the European Union: Dealing with data below the limit of quantification. Journal of Veterinary Pharmacology and Therapeutics, Wiley-Blackwell, 2017, 40 (2), pp.116-122. ⟨10.1111/jvp.12343⟩. ⟨anses-01421392⟩
  • Anne Chevance, Anne-Marie Jacques, Michel Laurentie, Pascal Sanders, Jérôme Henri. The present and future of withdrawal period calculations for milk in the European Union: Focus on heterogeneous, nonmonotonic data. Journal of Veterinary Pharmacology and Therapeutics, Wiley-Blackwell, 2017, 40 (3), pp.218-230. ⟨10.1111/jvp.12351⟩. ⟨anses-01419605⟩
  • Brigitte Roudaut, Isabelle Fournet, Dominique Hurtaud Pessel, Pascal Sanders. Recherche de résidus d'antibiotiques dans la filière bovine française: des progrès à intensifier. Point Vétérinaire (Éd. Expert Rural), 2017, pp.64-68. ⟨anses-01555594⟩
  • Ijaz Ahmad, Lingli Huang, Haihong Hao, Pascal Sanders, Zonghui Yuan. Corrigendum to “Application of PK/PD Modeling in Veterinary Field: Dose Optimization and Drug Resistance Prediction”. BioMed Research International , Hindawi Publishing Corporation, 2017, 2017, pp.1408737. ⟨10.1155/2017/1408737⟩. ⟨anses-01670638⟩
  • Ijaz Ahmad, Lingli Huang, Haihong Hao, Pascal Sanders, Zonghui Yuan. Application of PK/PD Modeling in Veterinary Field: Dose Optimization and Drug Resistance Prediction. BioMed Research International , Hindawi Publishing Corporation, 2016, pp.1-13. ⟨10.1155/2016/5465678⟩. ⟨anses-01347805⟩
  • Haihong Hao, Pascal Sanders, Zahid Iqbal, Yuliang Wang, Guyue Cheng, et al.. The Risk of Some Veterinary Antimicrobial Agents on Public Health Associated with Antimicrobial Resistance and their Molecular Basis. Frontiers in Microbiology, Frontiers Media, 2016, 7, pp.1626 - 1637. ⟨10.3389/fmicb.2016.01626⟩. ⟨anses-01418411⟩
  • Pascal Sanders, Jérôme Henri, Michel Laurentie. Tools to evaluate pharmacokinetics data for establishing maximum residue limits for approved veterinary drugs: examples from JECFA's work. Drug Testing and Analysis, John Wiley, 2016, 8 (5-6), pp.565-571. ⟨10.1002/dta.2006⟩. ⟨anses-01348712⟩
  • Jérôme Henri, Romain Carrez, Bertrand Méda, Michel Laurentie, Pascal Sanders. A physiologically based pharmacokinetic model for chickens exposed to feed supplemented with monensin during their lifetime. Journal of Veterinary Pharmacology and Therapeutics, Wiley-Blackwell, 2016, 40 (4), pp.1-13. ⟨10.1111/jvp.12370⟩. ⟨anses-01418236⟩
  • Ahmad Ijaz, Hao Haihong, Huang Lingli, Pascal Sanders, Wang Xu, et al.. Integration of PK/PD for dose optimization of Cefquinome against Staphylococcus aureus causing septicemia in cattle. Frontiers in microbiology, Frontiers Research Foundation, 2015, 6, pp.588. ⟨10.3389/fmicb.2015.00588⟩. ⟨anses-01203282⟩
  • Boudewijn Catry, Marco Cavaleri, Keith Baptiste, Kari Grave, Kornelia Grein, et al.. Use of colistin-containing products within the European Union and European Economic Area (EU/EEA): development of resistance in animals and possible impact on human and animal health. International Journal of Antimicrobial Agents, Elsevier, 2015, 46 (3), pp.297-306. ⟨10.1016/j.ijantimicag.2015.06.005⟩. ⟨anses-01193099⟩
  • Isabelle Kempf, Eric Jouy, Sophie A Granier, Claire Chauvin, Pascal Sanders, et al.. Comment on “Impact of antibiotic use in the swine industry”, by Mary D. Barton [Curr. Opin. Microbiol. 19 (June 2014) 9–15]. Current Opinion in Microbiology, Elsevier, 2015, pp.1-1. ⟨10.1016/j.mib.2015.06.013⟩. ⟨anses-01193151⟩
  • Eric Verdon, Mélaine Bessiral, Marie-Pierre Chotard, Pierrick Couëdor, Marie-Pierre Fourmond, et al.. The Monitoring of Triphenylmethane Dyes in Aquaculture Products Through the European Union Network of Official Control Laboratories. Journal of AOAC INTERNATIONAL, AOAC International, 2015, 98 (3), pp.649-657. ⟨10.5740/jaoacint.15-008⟩. ⟨anses-01193283⟩
  • Jérôme Henri, Antoine Huguet, Jean-Michel Delmas, Aurore Besson, Pascal Sanders, et al.. Low in vitro permeability of the cyanotoxin microcystin-LR across a Caco-2 monolayer: With identification of the limiting factors using modelling. Toxicon, Elsevier, 2014, pp.1-11. ⟨10.1016/j.toxicon.2014.07.023⟩. ⟨hal-01076975⟩
  • Claire Fromentin, Daniel Tomé, Francoise Nau, Laurent Flet, Catherine Luengo, et al.. Dietary Proteins Contribute Little to Glucose Production, Even Under Optimal Gluconeogenic Conditions in Healthy Humans. Diabetes, American Diabetes Association, 2013, 62 (5), pp.1435-1442. ⟨10.2337/db12-1208⟩. ⟨hal-01547485⟩
  • Pascal Sanders. La résistance aux antibiotiques en médecine vétérinaire : La résistance aux antibiotiques en milieu vétérinaire, quelles définitions ?. Les cahiers de la Recherche. Santé, Environnement, Travail, ANSES, 2013, Les multi-résistances, pp.53-55. ⟨anses-01709104⟩
  • Pascal Sanders, Michel Laurentie. Definitions of antimicrobial resistance in veterinary medicine: Epidemiological or prognostic//Définitions de la résistance aux antibiotiques en médecine vétérinaire: Épidémiologique ou pronostique. Bulletin de l'Académie Vétérinaire de France, Académie vétérinaire de France, 2012, 165 (3), pp.261-269. ⟨anses-00749794⟩
  • Natsuko Takakura, Pascal Sanders, Valérie Fessard, Ludovic Le Hégarat. In vitro combined cytotoxic effects of pesticide cocktails simultaneously found in the French diet.. Food and Chemical Toxicology, Elsevier, 2012, 52C, pp.153-162. ⟨10.1016/j.fct.2012.11.011⟩. ⟨hal-00766599⟩
  • Jérôme Henri, R. Maurice, G. Postollec, Estelle Dubreil-Cheneau, Brigitte Roudaut, et al.. Comparison of the oral bioavailability and tissue disposition of monensin and salinomycin in chickens and turkeys.. Journal of Veterinary Pharmacology and Therapeutics, Wiley-Blackwell, 2011, epub ahead of print. ⟨10.1111/j.1365-2885.2011.01285.x⟩. ⟨hal-00601106⟩
  • Engeline van Duijkeren, Boudewijn Catry, Christina Greko, Miguel A Moreno, M Constança Pomba, et al.. Review on methicillin-resistant Staphylococcus pseudintermedius.. Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2011, 66 (12), pp.2705-14. ⟨10.1093/jac/dkr367⟩. ⟨hal-00653456⟩
  • Anne-Sylvie Kesteman, Agnès Perrin-Guyomard, Michel Laurentie, Pascal Sanders, Pierre-Louis Toutain, et al.. Emergence of resistant Klebsiella pneumoniae in the intestinal tract during successful treatment of Klebsiella pneumoniae lung infection in rats.. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2010, 54 (7), pp.2960-4. ⟨10.1128/AAC.01612-09⟩. ⟨hal-00517528⟩
  • Anne-Sylvie Kesteman, Aude A Ferran, Agnès Perrin-Guyomard, Michel Laurentie, Pascal Sanders, et al.. Influence of inoculum size and marbofloxacin plasma exposure on the amplification of resistant subpopulations of Klebsiella pneumoniae in a rat lung infection model.. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2009, 53 (11), pp.4740-8. ⟨10.1128/AAC.00608-09⟩. ⟨hal-00517531⟩
  • Anne-Sylvie Kesteman, Aa Ferran, A Perrin-Guyomard, Michel Laurentie, Pascal Sanders, et al.. Impact of marbofloxacin dosing regimen on intestinal flora in a dixenic rat model with Klebsiella pneumoniae lung infection. Journal of Veterinary Pharmacology and Therapeutics, Wiley-Blackwell, 2009, 32 (s1), pp.150-151. ⟨hal-02656744⟩
  • Anne-Sylvie Kesteman, Aa Ferran, A Perrin-Guyomard, Michel Laurentie, Pascal Sanders, et al.. Influence of inoculum size and dosing regimen on the selection of marbofloxacin resistant mutants in experimental rat Klebsiella pneumoniae lung infection. Journal of Veterinary Pharmacology and Therapeutics, Wiley-Blackwell, 2009, 32 (s1), pp.63-63. ⟨hal-02654001⟩
  • Valerie Gaudin, Murielle Juhel-Gaugain, Jean-Pierre Morétain, Pascal Sanders. AFNOR validation of Premi Test, a microbiological-based screening tube-test for the detection of antimicrobial residues in animal muscle tissue.. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2008, 25 (12), pp.1451-1464. ⟨10.1080/02652030802429088⟩. ⟨hal-00606192⟩
  • Pascal Sanders, Dominique Meunier, Gabrielle Moulin, A Dernburg, M Bruneau, et al.. Modalités d'appréciation de l'utilisation des antibiotiques et du développement de la résistance aux antibiotiques en production bovine. Bulletin des G.T.V., 2005, pp.37-42. ⟨hal-02673775⟩
  • Claire Chauvin, Isabelle Bouvarel, Pierre-Alexandre Belœil, Jean-Pierre Orand, Didier Guillemot, et al.. A pharmaco-epidemiological analysis of factors associated with antimicrobial consumption level in turkey broiler flocks. Veterinary Research, BioMed Central, 2005, 36 (2), pp.199-211. ⟨10.1051/vetres:2004064⟩. ⟨hal-00902967⟩
  • Claire Chauvin, François Madec, Didier Guillemot, Pascal Sanders. The crucial question of standardisation when measuring drug consumption. Veterinary Research, BioMed Central, 2001, 32 (6), pp.533-543. ⟨10.1051/vetres:2001145⟩. ⟨hal-00902729⟩
  • Jean-Louis Martel, Florence Tardy, Pascal Sanders, Jacques Boisseau. New trends in regulatory rules and surveillance of antimicrobial resistance in bacteria of animal origin. Veterinary Research, BioMed Central, 2001, 32 (3-4), pp.381-392. ⟨10.1051/vetres:2001131⟩. ⟨hal-00902710⟩

Conference papers5 documents

  • Pascal Sanders. Value of farm-level interventions. Antimicrobial resistance in the food chain - from science to policy, Nov 2018, Utrecht, Netherlands. ⟨anses-01984947⟩
  • Francoise Nau, Claire Gaudichon, Pascal Sanders, Catherine Guérin-Dubiard, Didier Dupont. OVONUTRIAL project: technologies impact on nutritional value and allergenicity of egg proteins. XIIIth European symposium on the quality of eggs and eggproducts, Jun 2009, Turku (FI), Finland. ⟨hal-00730037⟩
  • As Kesteman, Aa Ferran, A Perrin-Guyomard, Michel Laurentie, Pascal Sanders, et al.. Impact d'une fluoroquinolone sur la flore pathogène et la flore commensale intestinale dans un modèle d'infection pulmonaire par Klebsiella pneumoniae chez le rat dixénique. Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu. ⟨hal-02822116⟩
  • As Kesteman, Aa Ferran, A Perrin-Guyomard, Michel Laurentie, Pascal Sanders, et al.. Influence of inoculum size and dosing regimen on the selection of marbofloxacin resistant mutants in experimental rat Klebsiella pneumoniae lung infection. 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany. ⟨hal-02751484⟩
  • As Kesteman, Aa Ferran, A Perrin-Guyomard, Michel Laurentie, Pascal Sanders, et al.. Impact of marbofloxacin dosing regimen on intestinal flora in a dixenic rat model with Klebsiella pneumoniae lung infection. 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany. ⟨hal-02752387⟩

Poster communications1 document

  • As Kesteman, Aude Ferran, A Perrin-Guyomard, Michel Laurentie, Pascal Sanders, et al.. Influence of inoculum size and dosing regimen on the selection of marbofloxacin resistant mutants in experimental Klebsiella pneumonia lung infection in rats. 3rd Symposium on Antimicrobial Resistance in Animals and the Environment, 2009, Tours, France. pp.Inconnu, 2009. ⟨hal-02815427⟩

Book sections2 documents

  • Pascal Sanders. Médicaments vétérinaires et santé humaine. CNRS. L’alimentation à découvert, 2015, 978-2-271-08300-5. ⟨anses-01203327⟩
  • Anne Brisabois, Isabelle Kempf, Dominique Meunier, Yves Millemann, Pascal Sanders, et al.. Section II : Impact de l'usage des antibiotiques sur la résistance chez l'animal (incluant la surveillance de la résistance batérienne chez l'animal). Usages vétérinaires des antibiotiques, résistance bactérienne et conséquences pour la santé humaine, AFSSA - Agence Française de Sécurité Sanitaire des Aliments, 2006. ⟨hal-02816483⟩

Other publications1 document

  • Joe Boison, Pascal Sanders, Alan Chicoine, Stefan Scheid. Zilpaterol hydrochloride. 2016. ⟨anses-01335049⟩

Reports1 document

  • Jean-François Guillot, Jacqueline Bastien, Joel Bertin, Alain Bousquet-Melou, Mireille Bruneau, et al.. Evaluation des risques d’émergence d’antibiorésistances liés aux modes d’utilisation des antibiotiques dans le domaine de la santé animale. [Technical Report] ANSES. 2014. ⟨hal-01590019⟩