Pascal Pigeon

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91000

Identifiants chercheurs

pascal-pigeon
ResearcherId : F-9758-2014
IdRef : 196560039
0000-0001-5374-5346
Google Scholar : http://scholar.google.fr/citations?user=JA7gN3sAAAAJ

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https://ipcm.fr/index.php/en/en-research/en-presentation-chembio-group/en-chembio-group-members/en-pascal-pigeon/

Présentation

Domaines de recherche

Chimie organique Chimie thérapeutique

Publications

"anne-vessieres"

	Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure Pierre Idlas , Elise Lepeltier , Guillaume Bastiat , Pascal Pigeon , Michael Mcglinchey Langmuir, 2023, 39 (5), pp.1885-1896. ⟨10.1021/acs.langmuir.2c02910⟩ Article dans une revue hal-03955374v1
	Synthesis, Electrochemical and Fluorescence Properties of the First Fluorescent Member of the Ferrocifen Family and of its Oxidized Derivatives Charles Fayolle , Pascal Pigeon , Nathalie Fischer-Durand , Michèle Salmain , Olivier O. Buriez Molecules, 2022, 27 (19), pp.6690. ⟨10.3390/molecules27196690⟩ Article dans une revue hal-03807919v1
	Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens Juan Sanz Garcia , Marie Gaschard , Isabelle Navizet , Mehdi Sahihi , Siden Top European Journal of Inorganic Chemistry, 2022, 2022 (9), pp.e202101075. ⟨10.1002/ejic.202101075⟩ Article dans une revue hal-03527077v1
	Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes Anne Vessieres , Emie Quissac , Nolwenn Lemaire , Agusti Alentorn , Patrycja Domeracka International Journal of Molecular Sciences, 2021, 22 (19), pp.10404. ⟨10.3390/ijms221910404⟩ Article dans une revue hal-03356305v1
	Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects Federica Tonolo , Michèle Salmain , Valeria Scalcon , Siden Top , Pascal Pigeon ChemMedChem, 2019, 14 (19), pp.1717-1726. ⟨10.1002/cmdc.201900430⟩ Article dans une revue hal-02282225v1
	Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells Valeria Scalcon , Michèle Salmain , Alessandra Folda , Siden Top , Pascal Pigeon Metallomics, 2017, 9 (7), pp.949-959. ⟨10.1039/C7MT00121E⟩ Article dans une revue hal-01611386v1
	Side-Chain Effects on the 1-(Bis-aryl-methylidene)-[3]ferrocenophane Skeleton: Antiproliferative Activity against TNBC Cancer Cells and Comparison with the Acyclic Ferrocifen Series Meral Gormen , Pascal Pigeon , Yong Wang , Anne Vessières , Siden Top European Journal of Inorganic Chemistry, 2017, Special Issue: The Multifaceted Chemistry of Ferrocene (Cluster Issue), 2017 (2), pp.454-465. ⟨10.1002/ejic.201601088⟩ Article dans une revue hal-01408995v1
	Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro Valeria Scalcon , Anna Citta , Alessandra Folda , Alberto Bindoli , Michèle Salmain Journal of Inorganic Biochemistry, 2016, 165, pp.146-151. ⟨10.1016/j.jinorgbio.2016.08.005⟩ Article dans une revue hal-01401089v1
	Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation Yong Wang , Marie-Aude Richard , Siden Top , Patrick M. Dansette , Pascal Pigeon Angewandte Chemie, 2016, 55 (35), pp.10431-10434. ⟨10.1002/anie.201603931⟩ Article dans une revue hal-01345781v1
	Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites Marie-Aude Richard , Didier Hamels , Pascal Pigeon , Siden Top , Patrick M. Dansette ChemMedChem, 2015, 10 (6), pp.981-990. ⟨10.1002/cmdc.201500075⟩ Article dans une revue hal-01230370v1
	Evidence for Targeting Thioredoxin Reductases with Ferrocenyl Quinone Methides. A Possible Molecular Basis for the Antiproliferative Effect of Hydroxyferrocifens on Cancer Cells Anna Citta , Alessandra Folda , Alberto Bindoli , Pascal Pigeon , Siden Top Journal of Medicinal Chemistry, 2014, 57 (21), pp.8849-8859. ⟨10.1021/jm5013165⟩ Article dans une revue hal-01230376v1
	Ferrocifen derivatives that induce senescence in cancer cells: selected examples Celine Bruyere , Veronique Mathieu , Anne Vessières , Pascal Pigeon , Siden Top Journal of Inorganic Biochemistry, 2014, 141, pp.144-151. ⟨10.1016/j.jinorgbio.2014.08.015⟩ Article dans une revue hal-01230377v1
	Ferrocenyl flavonoid-induced morphological modifications of endothelial cells and cytotoxicity against B16 murine melanoma cells Jean-Philippe Monserrat , Keshri Nath Tiwari , Lionel Quentin , Pascal Pigeon , Gérard Jaouen Journal of Organometallic Chemistry, 2013, 734 (SI), pp.78-85. ⟨10.1016/j.jorganchem.2012.12.031⟩ Article dans une revue hal-01230380v1
	The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer Anne-Laure Lainé , Eric Adriaenssens , Anne Vessières , Gérard Jaouen , Cyril Corbet Biomaterials, 2013, 34 (28), pp.6949-6956. ⟨10.1016/j.biomaterials.2013.05.065⟩ Article dans une revue hal-01230382v1
	Synthesis and Antiproliferative Effects of [3]Ferrocenophane Transposition Products and Pinacols Obtained from McMurry Cross-Coupling Reactions Meral Görmen , Pascal Pigeon , Elisabeth A. Hillard , Anne Vessières , Michel Huché Organometallics, 2012, 31 (16), pp.5856-5866. ⟨10.1021/om300382h⟩ Article dans une revue hal-01230386v1
	Ferrocenyl catechols: synthesis, oxidation chemistry and anti-proliferative effects on MDA-MB-231 breast cancer cells Yong Leng Kelvin Tan , Pascal Pigeon , Siden Top , Eric Labbé , Olivier Buriez Dalton Transactions, 2012, 41 (25), pp.7537-7549. ⟨10.1039/c2dt30700f⟩ Article dans une revue hal-01230385v1
	Evaluation of bactericidal and fungicidal activity of ferrocenyl or phenyl derivatives in the diphenyl butene series Mehdi El Arbi , Pascal Pigeon , Siden Top , Ali Rhouma , Sami Aifa Journal of Organometallic Chemistry, 2011, 696 (5), pp.1038-1048. ⟨10.1016/j.jorganchem.2010.09.015⟩ Article dans une revue hal-01230388v1
	A new series of ferrocifen derivatives, bearing two aminoalkyl chains, with strong antiproliferative effects on breast cancer cells Pascal Pigeon , Siden Top , Anne Vessières , Michel Huché , Meral Goermen New Journal of Chemistry, 2011, 35 (10), pp.2212-2218. ⟨10.1039/c1nj20192a⟩ Article dans une revue hal-01230387v1
	Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines Meral Görmen , Pascal Pigeon , Siden Top , Anne Vessières , Marie-Aude Plamont MedChemComm, 2010, 1 (2), pp.149-151. ⟨10.1039/c0md00026d⟩ Article dans une revue hal-01230393v1
	Synthesis, Cytotoxicity, and COMPARE Analysis of Ferrocene and [3]Ferrocenophane Tetrasubstituted Olefin Derivatives against Human Cancer Cells Meral Goermen , Pascal Pigeon , Siden Top , Elisabeth A. Hillard , Michel Huché ChemMedChem, 2010, 5 (12), pp.2039-2050. ⟨10.1002/cmdc.201000286⟩ Article dans une revue hal-01230394v1
	Comparative toxicity of [3]ferrocenophane and ferrocene moieties on breast cancer cells Meral Görmen , Damian Plazuk , Pascal Pigeon , Elisabeth A. Hillard , Marie-Aude Plamont Tetrahedron Letters, 2010, 51 (1), pp.118-120. ⟨10.1016/j.tetlet.2009.10.102⟩ Article dans une revue hal-01230391v1
	The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-1-ene compounds against breast cancer cells Pascal Pigeon , Siden Top , Ouardia O. Zekri , Elisabeth A. Hillard , Anne A. Vessieres Journal of Organometallic Chemistry, 2009, 694, pp.895-901. ⟨10.1016/j.jorganchem.2008.11.035⟩ Article dans une revue hal-00376093v1
	A [3]Ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines Damian Plazuk , Anne Vessières , Elisabeth A. Hillard , Olivier Buriez , Eric Labbé Journal of Medicinal Chemistry, 2009, 52, pp.4964-4967. ⟨10.1021/jm900297x⟩ Article dans une revue hal-00448988v1
	Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol Yong Leng Kelvin Tan , Pascal Pigeon , Elisabeth A. Hillard , Siden Top , Marie-Aude Plamont Dalton Transactions, 2009, 48, pp.10871-10881. ⟨10.1039/b913570g⟩ Article dans une revue hal-01230395v1
	Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds Ouardia Zekri , Elisabeth A. Hillard , Siden Top , Anne Vessières , Pascal Pigeon Dalton Transactions, 2009, 22, pp.4318-4326. ⟨10.1039/B819812H⟩ Article dans une revue hal-00449003v1
	Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment. Anh Nguyen , Véronique Marsaud , Céline Bouclier , Siden Top , Anne Vessieres International Journal of Pharmaceutics, 2008, 347 (1-2), pp.128-35. ⟨10.1016/j.ijpharm.2007.06.033⟩ Article dans une revue hal-00180710v1
	Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas. Emilie Allard , Catherine Passirani , Emmanuel Garcion , Pascal Pigeon , Anne Vessières Journal of Controlled Release, 2008, 130 (2), pp.146-53. ⟨10.1016/j.jconrel.2008.05.027⟩ Article dans une revue inserm-00343557v1
	Ferrocenyl compounds possessing protected phenol and thiophenol groups: Synthesis, X-ray structure, and in vitro biological effects against breast cancer Julia B. Heilmann , Elisabeth A. Hillard , Marie-Aude Plamont , Pascal Pigeon , Michael Bolte Journal of Organometallic Chemistry, 2008, 693 (8-9), pp.1716-1722. ⟨10.1016/j.jorganchem.2007.12.011⟩ Article dans une revue hal-01230397v1
	Organometallic diphenols: The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells Elisabeth A. Hillard , Anne Vessières , Siden Top , Pascal Pigeon , Konrad Kowalski Journal of Organometallic Chemistry, 2007, 692 (6), pp.1315-1326. ⟨10.1016/j.jorganchem.2006.10.041⟩ Article dans une revue hal-01230402v1
	The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif Elisabeth A. Hillard , Pascal Pigeon , Anne Vessières , Christian Amatore , Gérard Jaouen Dalton Transactions, 2007, 43, pp.5073-5081. ⟨10.1039/b705030e⟩ Article dans une revue hal-01230399v1
	Ferrocifens and ferrocifenols as new potential weapons against breast cancer Anh Nguyen , Anne Vessières , Elisabeth A. Hillard , Siden Top , Pascal Pigeon CHIMIA, 2007, 61 (11), pp.716-724. ⟨10.2533/chimia.2007.716⟩ Article dans une revue hal-01230400v1
	Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen Anh Nguyen , Siden Top , Anne Vessières , Pascal Pigeon , Michel Huché Journal of Organometallic Chemistry, 2007, 692 (6, SI), pp.1219-1225. ⟨10.1016/j.jorganchem.2006.11.016⟩ Article dans une revue hal-01230401v1
	Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior Pascal Pigeon , Siden Top , Anne Vessières , Michel Huché , Elisabeth A. Hillard Journal of Medicinal Chemistry, 2005, 48 (8), pp.2814-2821. ⟨10.1021/jm049268h⟩ Article dans une revue hal-00093015v1
	First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects Gérard Jaouen , Siden Top , Anne Vessieres , Pascal Pigeon , Guy Leclercq Chemical Communications, 2001, 4, pp.383-384. ⟨10.1039/b009553m⟩ Article dans une revue hal-01230409v1

Pascal Pigeon

Présentation

Domaines de recherche

Publications

Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure

Synthesis, Electrochemical and Fluorescence Properties of the First Fluorescent Member of the Ferrocifen Family and of its Oxidized Derivatives

Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens

Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes

Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects

Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells

Side-Chain Effects on the 1-(Bis-aryl-methylidene)-[3]ferrocenophane Skeleton: Antiproliferative Activity against TNBC Cancer Cells and Comparison with the Acyclic Ferrocifen Series

Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro

Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

Evidence for Targeting Thioredoxin Reductases with Ferrocenyl Quinone Methides. A Possible Molecular Basis for the Antiproliferative Effect of Hydroxyferrocifens on Cancer Cells

Ferrocifen derivatives that induce senescence in cancer cells: selected examples

Ferrocenyl flavonoid-induced morphological modifications of endothelial cells and cytotoxicity against B16 murine melanoma cells

The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer

Synthesis and Antiproliferative Effects of [3]Ferrocenophane Transposition Products and Pinacols Obtained from McMurry Cross-Coupling Reactions

Ferrocenyl catechols: synthesis, oxidation chemistry and anti-proliferative effects on MDA-MB-231 breast cancer cells

Evaluation of bactericidal and fungicidal activity of ferrocenyl or phenyl derivatives in the diphenyl butene series

A new series of ferrocifen derivatives, bearing two aminoalkyl chains, with strong antiproliferative effects on breast cancer cells

Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines

Synthesis, Cytotoxicity, and COMPARE Analysis of Ferrocene and [3]Ferrocenophane Tetrasubstituted Olefin Derivatives against Human Cancer Cells

Comparative toxicity of [3]ferrocenophane and ferrocene moieties on breast cancer cells

The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-1-ene compounds against breast cancer cells

A [3]Ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines

Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol

Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds

Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment.

Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas.

Ferrocenyl compounds possessing protected phenol and thiophenol groups: Synthesis, X-ray structure, and in vitro biological effects against breast cancer

Organometallic diphenols: The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells

The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif

Ferrocifens and ferrocifenols as new potential weapons against breast cancer

Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen

Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior

First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects