Recherche - Archive ouverte HAL Accéder directement au contenu

Filtrer vos résultats

72 résultats
Page :
triés par
Image document

Targeting DNA Methylation with Small Molecules: What’s Next?

 Alexandre Erdmann , Ludovic Halby , Jacques Fahy , Paola B Arimondo
Journal of Medicinal Chemistry, 2015, 58 (6), pp.2569-2583. ⟨10.1021/jm500843d⟩
Article dans une revue hal-03043209v1

Identification of novel quinazoline derivatives as potent antiplasmodial agents

 Anne Bouchut , Dante Rotili , Christine Pierrot , Sergio Valente , Sophia Lafitte , et al.
European Journal of Medicinal Chemistry, 2019, 161, pp.277-291. ⟨10.1016/j.ejmech.2018.10.041⟩
Article dans une revue pasteur-03036828v1

DNA Methylation Analysis of ChIP Products at Single Nucleotide Resolution by Pyrosequencing®

 Céline Moison , Fanny Assemat , Antoine Daunay , Paola B Arimondo , Jörg Tost
Pyrosequencing, 1315, Springer, pp.315 - 333, 2015, Methods in Molecular Biology, 978-1-4939-2715-9. ⟨10.1007/978-1-4939-2715-9_22⟩
Chapitre d'ouvrage pasteur-03046253v1
Image document

The Many Faces of Epigenetics Oxford, December 2017

 Paola Arimondo , Anouk Barberousse , Gaëlle Pontarotti
Epigenetics, 2019, 14 (6), pp.623-631. ⟨10.1080/15592294.2019.1595298⟩
Article dans une revue pasteur-03026588v1

Combined analysis of DNA methylation and cell cycle in cancer cells

 Cecile Desjobert , Mounir El Mai , Tom Gerard-Hirne , Dominique Guianvarc'H , Arnaud Carrier , et al.
Epigenetics, 2015, 10 (1), pp.82-91. ⟨10.1080/15592294.2014.995542⟩
Article dans une revue hal-01365337v1
Image document

Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation

 Elie Hammam , Ameya Sinha , Sebastian Baumgarten , Flore Nardella , Jiaqi Liang , et al.
mBio, 2021, 12, pp.e02558-21. ⟨10.1128/mBio.02558-21⟩
Article dans une revue pasteur-03427780v1
Image document

New insights into the role of DNA methylation in Biomphalaria glabrata infection susceptibility

 Nelia Luviano , Marie Lopez , Fleur Gawehns , Cristian Chaparro , Paola B Arimondo , et al.
XVI Symposium on Schistosomiasis, FIOCRUZ, Nov 2022, Ouro Preto, Brazil
Communication dans un congrès hal-03963335v1

Triplex Formation on DNA Targets: How To Choose the Oligonucleotide

 Pierre Vekhoff , Alexandre Ceccaldi , David Polverari , Jean Pylouster , Claudio Pisano , et al.
Biochemistry, 2008, 47 (47), pp.12277-12289
Article dans une revue hal-01991319v1
Image document

Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum

 Flore Nardella , Irina Dobrescu , Haitham Hassan , Fabien Rodrigues , Sabine Thiberge , et al.
iScience, 2023, 26 (2), pp.105940. ⟨10.1016/j.isci.2023.105940⟩
Article dans une revue pasteur-04099097v1

Synthesis and biological study of a new series of 4'-O-Demethyl-epipodophyllotoxin derivatives.

 M. Duca , D. Guianvarc'H , P. Meresse , E. Bertounesque , Daniel Dauzonne , et al.
Journal of Medicinal Chemistry, 2005, 48(2), pp.593-603
Article dans une revue hal-00017177v1

C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development.

 Alexandre Ceccaldi , Arumugam Rajavelu , Christine Champion , Christine Rampon , Renata Z. Jurkowska , et al.
ChemBioChem, 2011, (12) (9), pp.1337-45. ⟨10.1002/cbic.201100130⟩
Article dans une revue istex hal-00632453v1

Dichapetalins from Dichapetalum species and their cytotoxic properties

 Christophe Long , Yannick Aussagues , Nicolas Molinier , Laurence Marcourt , Laure Vendier , et al.
Phytochemistry, 2013, 94, pp.184-191. ⟨10.1016/j.phytochem.2013.03.023⟩
Article dans une revue istex hal-02908188v1
Image document

Quinazoline-based analog of adenine as an antidote against MLL-rearranged leukemia cells: synthesis, inhibition assays and docking studies

 Corentin Bon , Magdalena Barbachowska , Nemanja Djokovic , Dusan Ruzic , Yang Si , et al.
Future Medicinal Chemistry, 2022, 14 (8), pp.557-570. ⟨10.4155/fmc-2021-0251⟩
Article dans une revue pasteur-03704094v1

Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors

 Grégoire Rondelet , Laurence Fleury , Céline Faux , Véronique Masson , Jean Dubois , et al.
Future Medicinal Chemistry, 2017, 9 (13), pp.1465-1481. ⟨10.4155/fmc-2017-0074⟩
Article dans une revue pasteur-03033303v1

Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches

 Manuela Sabatino , Dante Rotili , Alexandros Patsilinakos , Mariantonietta Forgione , Daniela Tomaselli , et al.
Journal of Computer-Aided Molecular Design, 2018, 32 (3), pp.435-458. ⟨10.1007/s10822-018-0096-z⟩
Article dans une revue pasteur-03033244v1

Drug Discovery Methods

 Marie Lopez , Maxime Leroy , Chantal Etiévant , Frédéric Ausseil , Alexandre Gagnon , et al.
Drug Discovery in Cancer Epigenetics, Elsevier, pp.63-95, 2016, ⟨10.1016/b978-0-12-802208-5.00003-5⟩
Chapitre d'ouvrage hal-02399880v1
Image document

DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness

 Arnaud Carrier , Cécile Desjobert , Loic Ponger , Laurence Lamant , Matias Bustos , et al.
eLife, 2022, 11, pp.e78587. ⟨10.7554/eLife.78587⟩
Article dans une revue hal-03798060v1
Image document

Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein

 Corentin Bon , Yang Si , Melanie Pernak , Magdalena Barbachowska , Eva Levi-Acobas , et al.
Molecules, 2021, Special Issue The Chemical Biology Research in France, 26 (17), pp.5300. ⟨10.3390/molecules26175300⟩
Article dans une revue pasteur-03411876v1
Image document

Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs

 Dany Pechalrieu , Fanny Assemat , Ludovic Halby , Marlene Marcellin , Pengrong Yan , et al.
ACS Chemical Biology, 2020, 15 (4), pp.952-961. ⟨10.1021/acschembio.9b00965⟩
Article dans une revue pasteur-03026521v1
Image document

Epigenetically regulated PCDHB15 impairs aggressiveness of metastatic melanoma cells

 Arnaud Carrier , Cécile Desjobert , Valérie Lobjois , Lise Rigal , Florence Busato , et al.
Clinical Epigenetics, 2022, 14 (1), pp.156. ⟨10.1186/s13148-022-01364-x⟩
Article dans une revue pasteur-03946850v2
Image document

New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors

 Christina Gros , Laurence Fleury , Virginie Nahoum , Céline Faux , Sergio Valente , et al.
Journal of Biological Chemistry, 2014, 290, pp.6293 - 6302. ⟨10.1074/jbc.m114.594671⟩
Article dans une revue hal-03002969v1
Image document

A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation

 Lounis Yakhou , Anaelle Azogui , Nikhil Gupta , Julien Richard Albert , Fumihito Miura , et al.
Nucleic Acids Research, 2023, pp.gkad719. ⟨10.1093/nar/gkad719⟩
Article dans une revue pasteur-04197719v1
Image document

Targeting DOT1L for mixed-lineage rearranged leukemia

 Corentin Bon , Yang Si , Paola B Arimondo
Histone Modifications in Therapy, 20, Elsevier, pp.81-99, 2020, Translational Epigenetics, 978-0-12-816422-8. ⟨10.1016/B978-0-12-816422-8.00005-2⟩
Chapitre d'ouvrage pasteur-03414682v1
Image document

Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells

 Kosuke Yamaguchi , Xiaoying Chen , Brianna Rodgers , Fumihito Miura , Pavel Bashtrykov , et al.
2023
Pré-publication, Document de travail hal-04295168v1

The DNMT3A R882H mutant displays altered flanking sequence preferences

 Max Emperle , Arumugam Rajavelu , Stefan Kunert , Paola Arimondo , Richard Reinhardt , et al.
Nucleic Acids Research, 2018, 46 (6), pp.3130-3139. ⟨10.1093/nar/gky168⟩
Article dans une revue hal-02383683v1

DNA Methyltransferase Inhibitors: Development and Applications

 Marie Lopez , Ludovic Halby , Paola Arimondo
DNA Methyltransferases - Role and Function, pp.431-473, 2016, ⟨10.1007/978-3-319-43624-1_16⟩
Chapitre d'ouvrage hal-02399858v1
Image document

Wandering along the epigenetic timeline

 Clémence Topart , Emilie Werner , Paola B Arimondo
Clinical Epigenetics, 2020, 12 (1), pp.97. ⟨10.1186/s13148-020-00893-7⟩
Article dans une revue pasteur-03043377v1
Image document

DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge

 Omar Castillo-Aguilera , Patrick Depreux , Ludovic Halby , Paola B. Arimondo , Laurence Goossens
Biomolecules, 2017, 7 (1), pp.3. ⟨10.3390/biom7010003⟩
Article dans une revue pasteur-03043584v1
Image document

Identification of Chemical Probes Targeting MBD2

 Diane Erdmann , Jean Contreras , Rémy Le Meur , Bruno Vitorge , Vincent Saverat , et al.
ACS Chemical Biology, 2022, Published as part of the ACS Chemical Biology special issue “Epigenetics 2022”., 17 (6), pp.1415-1426. ⟨10.1021/acschembio.1c00959⟩
Article dans une revue pasteur-03688129v1
Image document

The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor

 Nelia Luviano , Marie Lopez , Fleur Gawehns , Cristian Chaparro , Paola B Arimondo , et al.
Epigenetics & Chromatin, 2021, 14 (1), pp.48. ⟨10.1186/s13072-021-00422-7⟩
Article dans une revue pasteur-03427775v2
Page :