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53 résultats

	Pour les 53 documents Envoyer sur ORCID RSS ATOM Exporter BibTeX XML-TEI CSV RTF EndNote PDF HTML Export avancé	Page : Page précédente 1 2 Page suivante	triés par Pertinence Auteur A→Z Auteur Z→A Titre A→Z Titre Z→A Date de publication croissante Date de publication décroissante Date de dépôt croissante Date de dépôt décroissante

		Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors Amélie Bruel , Romain Bénéteau , Mylène Chabanne , Olivier Lozach , Rémy Le Guevel , et al. Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5037 - 5040. ⟨10.1016/j.bmcl.2014.09.017⟩ Article dans une revue hal-01086026v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A facile consensus ranking approach enhances virtual screening robustness and identifies a cell-active DYRK1α inhibitor Maria Mavrogeni , Filippos Pronios , Danae Zareifi , Sofia Vasilakaki , Olivier Lozach , et al. Future Medicinal Chemistry, 2018, 10 (20), pp.2411 - 2430. ⟨10.4155/fmc-2018-0198⟩ Article dans une revue hal-01906403v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: Synthesis, biological evaluation and molecular modeling studies Cédric Logé , Alexandra Testard , Valérie Thiéry , Olivier Lozach , Mélina Blairvacq , et al. European Journal of Medicinal Chemistry, 2008, 43 (7), pp.1469-1477. ⟨10.1016/j.ejmech.2007.09.020⟩ Article dans une revue istex hal-02357774v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors. Rajâa Boulahjar , Aziz Ouach , Stéphane Bourg , Pascal Bonnet , Olivier Lozach , et al. European Journal of Medicinal Chemistry, 2015, 101, pp.274-287. ⟨10.1016/j.ejmech.2015.06.046⟩ Article dans une revue hal-01212495v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted Pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors Oussama Dehbi , Abdellatif Tikad , Stéphane Bourg , Pascal Bonnet , Olivier Lozach , et al. European Journal of Medicinal Chemistry, 2014, 80, pp.352-363. ⟨10.1016/j.ejmech.2014.04.055⟩ Article dans une revue hal-02904758v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis and evaluation of the antiproliferative activity of novel thiazoloquinazolinone kinases inhibitors. Alexandra Testard , Laurent Picot , Olivier Lozach , Melina Blairvacq , Laurent Meijer , et al. Journal of Enzyme Inhibition and Medicinal Chemistry, 2005, 20 (6), pp.557-568. ⟨10.1080/14756360500212399⟩ Article dans une revue hal-01443570v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		An efficient method for the preparation of new analogs of Leucettamine B under solvent-free microwave irradiation. Mansour Debdab , Stéven Renault , Samar Eid , Olivier Lozach , Laurent Meijer , et al. Heterocycles, 2009, pp.1191-1203 Article dans une revue hal-00411456v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Novel Tetrahydropyrido[1,2- a ]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts Rajâa Boulahjar , Aziz Ouach , Chiurato Matteo , Stéphane Bourg , Myriam Ravache , et al. Journal of Medicinal Chemistry, 2012, 55 (22), pp.9589-9606. ⟨10.1021/jm3008536⟩ Article dans une revue hal-02904751v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp. Dominique Laurent , Valérie Jullian , Arnaud Parenty , Martine Knibiehler , Dominique Dorin , et al. Bioorganic and Medicinal Chemistry, 2006, 14(13), pp.4477-4482 Article dans une revue hal-00090890v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3 Alexandra Testard , Cédric Logé , Benoît Léger , Jean-Michel Robert , Olivier Lozach , et al. Bioorganic and Medicinal Chemistry Letters, 2006, 16 (13), pp.3419-3423. ⟨10.1016/j.bmcl.2006.04.006⟩ Article dans une revue istex hal-02357746v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors Aziz Ouach , Rajâa Boulahjar , Christine Vala , Stéphane Bourg , Pascal Bonnet , et al. European Journal of Medicinal Chemistry, 2016, 115, pp.311--325. ⟨10.1016/j.ejmech.2016.02.072⟩ Article dans une revue hal-01295635v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthetic phospholipids and phospho-bola-amphiphiles for nucleic acid delivery Mathieu Berchel , Olivier Lozach , Wilfried Berthe , Sylvie Hernot , Hélène Couthon , et al. Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 191 (11-12), pp.1485 - 1487. ⟨10.1080/10426507.2016.1212049⟩ Article dans une revue hal-01539538v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis and kinase inhibitory activity of novel substituted indigoids Anne Beauchard , Helene Laborie , Hervé Rouillard , Olivier Lozach , Yoan Ferandin , et al. Bioorganic and Medicinal Chemistry Letters, 2009, 17 (17), pp.6257-6263. ⟨10.1016/j.bmc.2009.07.051⟩ Article dans une revue istex hal-02357759v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Natural aristolactams and aporphine alkaloids as inhibitors of CDK1/cyclin B and DYRK1A. Guillaume Marti , Véronique Eparvier , Barbara Morleo , Jessica Le Ven , Cécile Apel , et al. Molecules, 2013, 18 (3), pp.3018-27. ⟨10.3390/molecules18033018⟩ Article dans une revue hal-00856752v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis, protein kinase inhibitory potencies and in vitro antiproliferative activities of meridianin derivatives. Francis Giraud , Georges Alves , Eric Debiton , Lionel Nauton , Vincent Thery , et al. Journal of Medicinal Chemistry, 2011, 54, pp.4474-4489 Article dans une revue hal-00609607v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents. Yoan Ferandin , Karima Bettayeb , Marina Kritsanida , Olivier Lozach , Panagiotis Polychronopoulos , et al. Journal of Medicinal Chemistry, 2006, 49 (15), pp.4638-49. ⟨10.1021/jm060314i⟩ Article dans une revue istex hal-00169375v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A Pd(0) based cross-coupling approach to the synthesis of 2-amidopurines and their evaluation as CDK inhibitors. Lucie Vandromme , Michel Legraverend , Sergio Kreimerman , Olivier Lozach , Laurent Meijer , et al. Bioorganic and Medicinal Chemistry, 2007, 15 (1), pp.130-41. ⟨10.1016/j.bmc.2006.10.003⟩ Article dans une revue istex hal-00169386v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors. Caroline Corbel , Qian Wang , Hadjira Bousserouel , Amel Hamdi , Bing Zhang , et al. Biotechnology Journal, 2011, 6 (7), pp.860-70. ⟨10.1002/biot.201100138⟩ Article dans une revue istex hal-00628746v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Dérivés d'imidazolones, procédé de préparation et applications biologiques. J.P. Bazureau , François Carreaux , Stéven Renault , Laurent Meijer , Olivier Lozach Patent n° : FR 291 9608 (A1). 2009 Brevet hal-00411458v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors. Mansour Debdab , Stéven Renault , Olivier Lozach , Laurent Meijer , Ludovic Paquin , et al. European Journal of Medicinal Chemistry, 2010, 45 (2), pp.805-10. ⟨10.1016/j.ejmech.2009.10.009⟩ Article dans une revue istex hal-00869769v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Identification of potential cellular targets of aloisine A by affinity chromatography. Caroline Corbel , Rose Haddoub , Damien Guiffant , Olivier Lozach , David Gueyrard , et al. Bioorganic and Medicinal Chemistry, 2009, 17 (15), pp.5572-82. ⟨10.1016/j.bmc.2009.06.024⟩ Article dans une revue istex hal-00416033v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis and biological evaluation of bolaamphiphilic sophorolipids Elisabeth Delbeke , Jonas Everaert , Olivier Lozach , Tony Le Gall , Mathieu Berchel , et al. ACS Sustainable Chemistry & Engineering, 2018, 6 (7), pp.8992-9005. ⟨10.1021/acssuschemeng.8b01354⟩ Article dans une revue hal-01806695v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Acridone Alkaloids from Glycosmis chlorosperma as DYRK1A Inhibitors Mehdi A. Beniddir , Erell Le Borgne , Bogdan I. Iorga , Nadège Loaëc , Olivier Lozach , et al. Journal of Natural Products, 2014, 77 (5), pp.1117-1122. ⟨10.1021/np400856h⟩ Article dans une revue hal-01162685v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Rebeccamycin derivatives as dual DNA damaging agents and potent checkpoint kinase 1 inhibitors. Christelle Marminon , Fabrice Anizon , Pascale Moreau , Bruno Pfeiffer , Alain Pierre , et al. Molecular Pharmacology, 2008, 74 (6), pp.1620-1629. ⟨10.1124/mol.108.049346⟩ Article dans une revue hal-00319800v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		An expeditious, environment-friendly, and microwave-assisted synthesis of 5-isatinylidenerhodanine derivatives Abdelmounaim Safer , Mustapha Rahmouni , François Carreaux , Ludovic Paquin , Olivier Lozach , et al. Chemical Papers, 2011, 65 (3), pp.332-337. ⟨10.2478/s11696-010-0104-9⟩ Article dans une revue hal-00869920v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors Christophe Labrière , Olivier Lozach , Mélina Blairvacq , Laurent Meijer , Catherine Guillou European Journal of Medicinal Chemistry, 2016, 124, pp.920 - 934. ⟨10.1016/j.ejmech.2016.08.069⟩ Article dans une revue hal-01517780v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents. Pamela Kassis , Joanna Brzeszcz , Valérie Bénéteau , Olivier Lozach , Laurent Meijer , et al. European Journal of Medicinal Chemistry, 2011, 46 (11), pp.5416-34. ⟨10.1016/j.ejmech.2011.08.048⟩ Article dans une revue istex hal-00720615v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Substitution of unsaturated lipid chains by thioether-containing lipid chains in cationic amphiphiles: physicochemical consequences and application for gene delivery Amal Bouraoui , Mathieu Berchel , Rosy Ghanem , Véronique Vie , Gilles Paboeuf , et al. Organic & Biomolecular Chemistry, 2019, 17 (14), pp.3609-3616. ⟨10.1039/c9ob00473d⟩ Article dans une revue hal-02088106v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Lipophosphoramidate-based bipolar amphiphiles: their syntheses and transfection properties Mathieu Berchel , Tony Le Gall , Olivier Lozach , Jean-Pierre Haelters , Tristan Montier , et al. Organic & Biomolecular Chemistry, 2016, 14 (10), pp.2846 - 2853. ⟨10.1039/C5OB02512E⟩ Article dans une revue hal-01539654v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases. T .B. Nguyen , Olivier Lozach , Georgiana Surpateanu , Qian Wang , Pascal Retailleau , et al. Journal of Medicinal Chemistry, 2012, 55 (6), pp.2811-9. ⟨10.1021/jm201727w⟩ Article dans une revue hal-00692489v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More

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Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors

A facile consensus ranking approach enhances virtual screening robustness and identifies a cell-active DYRK1α inhibitor

Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: Synthesis, biological evaluation and molecular modeling studies

Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.

Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted Pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors

Synthesis and evaluation of the antiproliferative activity of novel thiazoloquinazolinone kinases inhibitors.

An efficient method for the preparation of new analogs of Leucettamine B under solvent-free microwave irradiation.

Novel Tetrahydropyrido[1,2- a ]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts

Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp.

Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors

Synthetic phospholipids and phospho-bola-amphiphiles for nucleic acid delivery

Synthesis and kinase inhibitory activity of novel substituted indigoids

Natural aristolactams and aporphine alkaloids as inhibitors of CDK1/cyclin B and DYRK1A.

Synthesis, protein kinase inhibitory potencies and in vitro antiproliferative activities of meridianin derivatives.

3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.

A Pd(0) based cross-coupling approach to the synthesis of 2-amidopurines and their evaluation as CDK inhibitors.

First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors.

Dérivés d'imidazolones, procédé de préparation et applications biologiques.

Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors.

Identification of potential cellular targets of aloisine A by affinity chromatography.

Synthesis and biological evaluation of bolaamphiphilic sophorolipids

Acridone Alkaloids from Glycosmis chlorosperma as DYRK1A Inhibitors

Rebeccamycin derivatives as dual DNA damaging agents and potent checkpoint kinase 1 inhibitors.

An expeditious, environment-friendly, and microwave-assisted synthesis of 5-isatinylidenerhodanine derivatives

Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors

Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents.

Substitution of unsaturated lipid chains by thioether-containing lipid chains in cationic amphiphiles: physicochemical consequences and application for gene delivery

Lipophosphoramidate-based bipolar amphiphiles: their syntheses and transfection properties

Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases.