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Farnesyltransferase inhibition overcomes the adaptive resistance to osimertinib in EGFR-mutant NSCLC

 Sarah Figarol , Célia Delahaye , Rémi Gence , Raghda Asslan , Sandra Pagano , et al.
2022
Pré-publication, Document de travail hal-03843955v1
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RhoB Determines Tumor Aggressiveness in a Murine EGFRL858R-Induced Adenocarcinoma Model and Is a Potential Prognostic Biomarker for Lepidic Lung Cancer

 Olivier Calvayrac , Anne Pradines , Isabelle Raymond-Letron , Isabelle Rouquette , Emilie Bousquet , et al.
Clinical Cancer Research, 2014, 20 (24), pp.6541-6550. ⟨10.1158/1078-0432.CCR-14-0506⟩
Article dans une revue hal-03026035v1
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Matrix Metalloproteinase-10 Is Upregulated by Thrombin in Endothelial Cells and Increased in Patients With Enhanced Thrombin Generation

 Josune Orbe , José A Rodríguez , Olivier Calvayrac , Ricardo Rodríguez-Calvo , Cristina Rodríguez , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, 29 (12), pp.2109-2116. ⟨10.1161/ATVBAHA.109.194589⟩
Article dans une revue hal-03026100v1
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La GTPase RhoB, un nouvel acteur de la résistance adaptative aux inhibiteurs de la tyrosine kinase du récepteur de l'EGF dans les cancers du poumon

 Olivier Calvayrac , Anne Pradines , Julien Mazières , Gilles Favre
Médecine/Sciences, 2018, 34 (1), pp.12-14. ⟨10.1051/medsci/20183401003⟩
Article dans une revue hal-03025984v1
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Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma

 Emilie Bousquet Mur , Sara Bernardo , Laura Papon , Maicol Mancini , Eric Fabbrizio , et al.
Journal of Clinical Investigation, 2019, 130 (2), pp.612-624. ⟨10.1172/JCI126896⟩
Article dans une revue hal-03025960v1
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Fibulin-5 Is Up-regulated by Hypoxia in Endothelial Cells through a Hypoxia-inducible Factor-1 (HIF-1α)-dependent Mechanism

 Anna Guadall , Mar Orriols , Ricardo Rodríguez-Calvo , Olivier Calvayrac , Javier Crespo , et al.
Journal of Biological Chemistry, 2011, 286 (9), pp.7093-7103. ⟨10.1074/jbc.M110.162917⟩
Article dans une revue hal-03026092v1
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Vγ9Vδ2 T Cells Activation Through Phosphoantigens Can Be Impaired by a RHOB Rerouting in Lung Cancer

 Chloé Laplagne , Jean-Jacques Fournié , Mary Poupot , Stéphanie Cabantous , Sarah Figarol , et al.
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01396⟩
Article dans une revue hal-03025949v1
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RhoB loss induces Rac1-dependent mesenchymal cell invasion in lung cells through PP2A inhibition

 E Bousquet , O Calvayrac , J Mazières , I Lajoie-Mazenc , N Boubekeur , et al.
Oncogene, 2016, 35 (14), pp.1760-1769. ⟨10.1038/onc.2015.240⟩
Article dans une revue hal-03026032v1

Cytoplasmic p27 Kip1 promotes tumorigenesis via suppression of RhoB activity

 Olivier Calvayrac , Ada Nowosad , Stéphanie Cabantous , Lin-Po Lin , Sarah Figarol , et al.
Journal of Pathology, 2018, 247 (1), pp.60-71. ⟨10.1002/path.5167⟩
Article dans une revue hal-02329383v1
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The RAS ‐related GTP ase RHOB confers resistance to EGFR ‐tyrosine kinase inhibitors in non‐small‐cell lung cancer via an AKT ‐dependent mechanism

 Olivier Calvayrac , Julien Mazières , Sarah Figarol , Claire Marty‐detraves , Isabelle Raymond‐letron , et al.
EMBO Molecular Medicine, 2017, 9 (2), pp.238-250. ⟨10.15252/emmm.201606646⟩
Article dans une revue hal-03026004v1
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Over-expression of Neuron-derived Orphan Receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury

 Ricardo Rodríguez-Calvo , Anna Guadall , Olivier Calvayrac , María A Navarro , Judith Alonso , et al.
Human Molecular Genetics, 2013, 22 (10), pp.1949-1959. ⟨10.1093/hmg/ddt042⟩
Article dans une revue hal-03026064v1
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CCL20 Is Increased in Hypercholesterolemic Subjects and Is Upregulated By LDL in Vascular Smooth Muscle Cells

 Olivier Calvayrac , Ricardo Rodríguez-Calvo , Judith Alonso , Josune Orbe , Jose Luis Martín-Ventura , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, 31 (11), pp.2733-2741. ⟨10.1161/ATVBAHA.111.235721⟩
Article dans une revue hal-03026087v1
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Clinical and molecular analysis of lung cancers associated with fibrosing interstitial lung disease

 Valentin Héluain , Grégoire Prévot , Bastien Cabarrou , Olivier Calvayrac , Estelle Taranchon- Clermont , et al.
Respiratory Medicine and Research, 2023, 83, pp.100946. ⟨10.1016/j.resmer.2022.100946⟩
Article dans une revue hal-04308863v1
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Synergistic Effect of Thrombin and CD40 Ligand on Endothelial Matrix Metalloproteinase-10 Expression and Microparticle Generation In Vitro and In Vivo

 Sara Martínez de Lizarrondo , Carmen Roncal , Olivier Calvayrac , Cristina Rodríguez , Nerea Varo , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2012, 32 (6), pp.1477-1487. ⟨10.1161/ATVBAHA.112.248773⟩
Article dans une revue hal-03026076v1
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The RAS‐related GTPase RHOB confers resistance to EGFR‐tyrosine kinase inhibitors in non‐small‐cell lung cancer via an AKT‐dependent mechanism

 Olivier Calvayrac , Julien Mazières , Sarah Figarol , Claire Marty‐detraves , Isabelle Raymond‐letron , et al.
EMBO Molecular Medicine, 2017, 9 (2), pp.238 - 250. ⟨10.15252/emmm.201606646⟩
Article dans une revue hal-01504463v1
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Early Steps of Resistance to Targeted Therapies in Non-Small-Cell Lung Cancer

 Celia Delahaye , Sarah Figarol , Anne Pradines , Gilles Favre , Julien Mazieres , et al.
Cancers, 2022, 14 (11), pp.2613. ⟨10.3390/cancers14112613⟩
Article dans une revue hal-03820489v1

RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway

 Fatéméh Dubois , Maureen Keller , Olivier Calvayrac , Fabrice Soncin , Lily Hoa , et al.
Cancer Research, 2016, 76 (6), pp.1627-1640. ⟨10.1158/0008-5472.CAN-15-1008⟩
Article dans une revue hal-02037182v1
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