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Nicolas Jonckheere

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A novel anti-galectin-9 immunotherapy limits the early progression of pancreatic neoplastic lesions in transgenic mice

Alexandre Quilbe , Rami Mustapha , Belinda Duchêne , Abhishek Kumar , Elisabeth Werkmeister
Frontiers in Immunology, 2023, 14, pp.1267279. ⟨10.3389/fimmu.2023.1267279⟩
Article dans une revue hal-04469183v1
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Metabolism of pancreatic neuroendocrine tumors: what can omics tell us?

Arnaud Jannin , Anne-Frédérique Dessein , Christine Do Cao , Marie-Christine Vantyghem , Benjamin Chevalier
Frontiers in Endocrinology, 2023, 14, ⟨10.3389/fendo.2023.1248575⟩
Article dans une revue hal-04273585v1
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Evaluation of the expression of fatty acid synthase and O ‑GlcNAc transferase in patients with liver cancer by exploration of transcriptome databases and experimental approaches

Sadia Raab , Ninon Very , Belinda Duchêne , Pierre Rybarczyk , Nicolas Jonckheere
Oncology Letters, 2022, 23 (4), pp.105. ⟨10.3892/ol.2022.13225⟩
Article dans une revue hal-03608015v2
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TRPM7 Modulates Human Pancreatic Stellate Cell Activation.

Julie Auwercx , Philippe Kischel , Thibaut Lefebvre , Nicolas Jonckheere , Alison Vanlaeys
Cells, 2022, 11 (14), pp.2255. ⟨10.3390/cells11142255⟩
Article dans une revue hal-03740502v1
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Inositol (1,4,5)-Trisphosphate Receptors in Invasive Breast Cancer: A New Prognostic Tool?

Arthur Foulon , Pierre Rybarczyk , Nicolas Jonckheere , Eva Brabencova , Henri Sevestre
International Journal of Molecular Sciences, 2022, 23 (6), pp.2962. ⟨10.3390/ijms23062962⟩
Article dans une revue hal-04326232v1
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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis

Nicolas Stoup , Maxime Liberelle , Céline Schulz , Sumeyye Cavdarli , Romain Vasseur
Cancers, 2021, 13 (22), pp.5746. ⟨10.3390/cancers13225746⟩
Article dans une revue hal-03641795v1
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Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma

Nihad Boukrout , Mouloud Souidi , Fatima Lahdaoui , Belinda Duchêne , Bernadette Neve
Cancers, 2021, 13 (24), pp.6197. ⟨10.3390/cancers13246197⟩
Article dans une revue hal-03777017v1
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Mg2+ Transporters in Digestive Cancers

Julie Auwercx , Pierre Rybarczyk , Philippe Kischel , Isabelle Dhennin-Duthille , Denis Chatelain
Nutrients, 2021, 13 (1), pp.210. ⟨10.3390/nu13010210⟩
Article dans une revue hal-03195960v1
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Mucin expression, epigenetic regulation and patient survival: A toolkit of prognostic biomarkers in epithelial cancers

Nicolas Jonckheere , Audrey Vincent , Bernadette Neve , Isabelle van Seuningen
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2021, 1876 (1), pp.188538. ⟨10.1016/j.bbcan.2021.188538⟩
Article dans une revue hal-03294583v1
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A new pancreatic adenocarcinoma‐derived organoid model of acquired chemoresistance to FOLFIRINOX: first insight of the underlying mechanisms

Elsa Hadj Bachir , Charles Poiraud , Sonia Paget , Nicolas Stoup , Soumaya El Moghrabi
Biology of the Cell, inPress, ⟨10.1111/boc.202100003⟩
Article dans une revue hal-03369738v1

EGF-Containing Membrane-Bound Mucins: A Hidden ErbB2 Targeting Pathway?

Maxime Liberelle , Nicolas Jonckheere , Patricia Melnyk , Isabelle van Seuningen , Nicolas Lebègue
Journal of Medicinal Chemistry, 2020, 63 (10), pp.5074-5088. ⟨10.1021/acs.jmedchem.9b02001⟩
Article dans une revue hal-02955348v1
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Long-term consequences of one anastomosis gastric bypass on esogastric mucosa in a preclinical rat model

Matthieu Siebert , Lara Ribeiro-Parenti , Nicholas Nguyen , Muriel Hourseau , Belinda Duchêne
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-64425-2⟩
Article dans une revue hal-02617527v1

Long non-coding RNAs: the tentacles of chromatin remodeler complexes

Bernadette Neve , Nicolas Jonckheere , Audrey Vincent , Isabelle van Seuningen
Cellular and Molecular Life Sciences, 2020, 78 (4), pp.1139-1161. ⟨10.1007/s00018-020-03646-0⟩
Article dans une revue hal-03195963v1
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Unsupervised Hierarchical Clustering of Pancreatic Adenocarcinoma Dataset from TCGA Defines a Mucin Expression Profile that Impacts Overall Survival

Nicolas Jonckheere , Julie Auwercx , Elsa Hadj Bachir , Lucie Coppin , Nihad Boukrout
Cancers, 2020, 12 (11), pp.3309. ⟨10.3390/cancers12113309⟩
Article dans une revue hal-03003452v2

Fine-tuning autophagy in pancreatic adenocarcinoma: full blockage is required

Nicolas Jonckheere , Isabelle van Seuningen
Annals of translational medicine, 2019, 7 (S1), pp.S43-S43. ⟨10.21037/atm.2019.03.01⟩
Article dans une revue hal-02358435v1
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Fine-tuning autophagy in pancreatic adenocarcinoma: full blockage is required

Nicolas Jonckheere , Isabelle van Seuningen
Annals of translational medicine, 2019, 7 (S1), pp.S43-S43. ⟨10.21037/atm.2019.03.01⟩
Article dans une revue inserm-02341315v1
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TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727

Vincent Drubay , Nicolas Skrypek , Lucie Cordiez , Romain Vasseur , Céline Schulz
Cancers, 2018, 10 (8), pii: E254. ⟨10.3390/cancers10080254⟩
Article dans une revue inserm-02341320v1
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Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

Nicolas Jonckheere , Isabelle van Seuningen
Journal of Translational Medicine, 2018, 16 (1), pp.259. ⟨10.1186/s12967-018-1632-2⟩
Article dans une revue hal-02341297v1
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Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer

Bernadette Neve , Nicolas Jonckheere , Audrey Vincent , Isabelle van Seuningen
Cancers, 2018, 10 (11), pp.440. ⟨10.3390/cancers10110440⟩
Article dans une revue inserm-02341333v1

Depletion of MUC5B mucin in gastrointestinal cancer cells alters their tumorigenic properties: implication of the Wnt/β-catenin pathway

Fatima Lahdaoui , Mathieu Messager , Audrey Vincent , Flora Hec , Anne Gandon
Biochemical Journal, 2017, 474 (22), pp.3733-3746. ⟨10.1042/BCJ20170348⟩
Article dans une revue inserm-02341337v1
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The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting

Nicolas Jonckheere , Romain Vasseur , Isabelle Van Seuningen
Critical Reviews in Oncology/Hematology, 2017, 111, pp.7-19. ⟨10.1016/j.critrevonc.2017.01.002⟩
Article dans une revue inserm-02341607v1

Flagellin-Mediated Protection against Intestinal Yersinia pseudotuberculosis Infection Does Not Require Interleukin-22.

Rémi Porte , Laurye van Maele , Natalia Muñoz-Wolf , Benoit Foligné , Laure Dumoutier
Infection and Immunity, 2017, 85 (2), pp.e00806-16. ⟨10.1128/IAI.00806-16⟩
Article dans une revue inserm-01529315v1
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The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2

Nicolas Skrypek , Romain Vasseur , Audrey Vincent , Bélinda Duchêne , Isabelle van Seuningen
Oncotarget, 2015, 6 (13), pp.10853-1067. ⟨10.18632/oncotarget.3414⟩
Article dans une revue inserm-02341515v1
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Targeting MUC4 in pancreatic cancer: miRNAs

Nicolas Jonckheere , Fatima Lahdaoui , Isabelle van Seuningen
Oncoscience, 2015, 2 (10), pp.799-800. ⟨10.18632/oncoscience.249⟩
Article dans une revue hal-02905858v1
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Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells

Solange Tréhoux , Fatima Lahdaoui , Yannick Delpu , Florence Renaud , Emmanuelle Leteurtre
Biochimica et Biophysica Acta - Molecular Cell Research, 2015, ⟨10.1016/j.bbamcr.2015.05.033⟩
Article dans une revue hal-02905657v1
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Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival

Thibault Desurmont , Nicolas Skrypek , Alain Duhamel , Nicolas Jonckheere , Guillaume Millet
Cancer Science, 2015, 106 (3), pp.262-269. ⟨10.1111/cas.12603⟩
Article dans une revue hal-02954490v1
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miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer

F Lahdaoui , Y Delpu , A. Vincent , F. Renaud , M Messager
Oncogene, 2015, 34, pp.780 - 788. ⟨10.1038/onc.2014.11⟩
Article dans une revue hal-02905857v1
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The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways

Romain Vasseur , Nicolas Skrypek , Belinda Duchêne , Florence Renaud , Daniel Martínez-Maqueda
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2015, 1849 (12), pp.1375-1384. ⟨10.1016/j.bbagrm.2015.10.014⟩
Article dans une revue hal-02906327v1
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Cryosectioning the intestinal crypt-villus axis: An ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells

Audrey Vincent , Catherine Kazmierczak , Belinda Duchêne , Nicolas Jonckheere , Emmanuelle Leteurtre
Stem Cell Research, 2015, 14, ⟨10.1016/j.scr.2014.12.002⟩
Article dans une revue hal-02905864v1
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Of autophagy and in vivo pancreatic carcinogenesis: The p53 status matters!

Nicolas Jonckheere , Audrey Vincent , Isabelle Van Seuningen
Clinics and Research in Hepatology and Gastroenterology, 2014, 38 (4), pp.423-425. ⟨10.1016/j.clinre.2014.04.009⟩
Article dans une revue inserm-02341594v1
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Mucins and tumor resistance to chemotherapeutic drugs

Nicolas Jonckheere , Nicolas Skrypek , Isabelle Van Seuningen
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2014, 1846 (1), pp.142-151. ⟨10.1016/j.bbcan.2014.04.008⟩
Article dans une revue inserm-02341531v1
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The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42-44 MAPK, Akt, Bcl-2 and MMP13 pathways

Solange Tréhoux , Bélinda Duchêne , Nicolas Jonckheere , Isabelle van Seuningen
Biochemical and Biophysical Research Communications, 2014, ⟨10.1016/j.bbrc.2014.12.025⟩
Article dans une revue hal-02905690v1
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Helicobacter pylori urease and flagellin alter mucin gene expression in human gastric cancer cells

Michael Perrais , Christel Rousseaux , Marie-Paule Ducourouble , René Courcol , Pascal Vincent
Gastric Cancer, 2014, 17, pp.235-246. ⟨10.1007/s10120-013-0267-5⟩
Article dans une revue hal-02905802v1
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The MUC1 mucin regulates the tumorigenic properties of human esophageal adenocarcinomatous cells

Caroline Gronnier , Emilie Bruyère , Fatima Lahdaoui , Nicolas Jonckheere , Michael Perrais
Biochimica et Biophysica Acta - Molecular Cell Research, 2014, ⟨10.1016/j.bbamcr.2014.06.021⟩
Article dans une revue hal-02905652v1
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Comment on: Functional MUC4 suppress epithelial-mesenchymal transition in lung adenocarcinoma metastasis. Gao L, Liu J, Zhang B, Zhang H, Wang D, Zhang T, Liu Y, Wang C. Tumour Biol. 2013, in press

Nicolas Jonckheere , Isabelle van Seuningen
Tumor Biology, 2014, 35 (4), pp.3941-3942. ⟨10.1007/s13277-013-1390-y⟩
Article dans une revue inserm-02371186v1
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Membrane-bound mucin modular domains: from structure to function.

Nicolas Jonckheere , Nicolas Skrypek , Frédéric Frénois , Isabelle van Seuningen
Biochimie, 2013, 95 (6), pp.1077-86. ⟨10.1016/j.biochi.2012.11.005⟩
Article dans une revue inserm-00807818v1
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The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family.

Nicolas Skrypek , Bélinda Duchêne , Mohamed Hebbar , Emmanuelle Leteurtre , Isabelle van Seuningen
Oncogene, 2013, 32 (13), pp.1714-23. ⟨10.1038/onc.2012.179⟩
Article dans une revue inserm-00807837v1

Membrane-bound mucin modular domains: From structure to function

Nicolas Jonckheere , Frédéric Frénois , Isabelle van Seuningen , Nicolas Q1 , Nicolas Skrypek
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2012, ⟨10.1016/j.biochi.2012.11.005⟩
Article dans une revue hal-02905700v1
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The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways.

Nicolas Jonckheere , Nicolas Skrypek , Johann Merlin , Anne Frédérique Dessein , Patrick Dumont
PLoS ONE, 2012, 7 (2), pp.e32232. ⟨10.1371/journal.pone.0032232⟩
Article dans une revue inserm-00807830v1
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GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells.

Nicolas Jonckheere , Audrey Vincent , Hélène Franquet-Ansart , Janneke Witte-Bouma , Anita Korteland-van Male
BBA - Biochimica et Biophysica Acta, 2012, 1819 (8), pp.869-76. ⟨10.1016/j.bbagrm.2012.04.003⟩
Article dans une revue inserm-00807845v1
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Tif1γ Suppresses Murine Pancreatic Tumoral Transformation by a Smad4-Independent Pathway

David Vincent , Johann Gout , Nicolas Chuvin , Vanessa Arfi , Roxane M. Pommier
American Journal of Pathology, 2012, 180 (6), pp.2214-2221. ⟨10.1016/j.ajpath.2012.02.006⟩
Article dans une revue hal-02954464v1
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The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors.

Nicolas Jonckheere , Amélie Velghe , Marie-Paule Ducourouble , Marie-Christine Copin , Ingrid B. Renes
FEBS Journal, 2011, 278 (2), pp.282-94. ⟨10.1111/j.1742-4658.2010.07945.x⟩
Article dans une revue inserm-00807850v1
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The MUC4 membrane-bound mucin regulates esophageal cancer cell proliferation and migration properties: Implication for S100A4 protein

Emilie Bruyère , Nicolas Jonckheere , Frédéric Frénois , Christophe Mariette , Isabelle van Seuningen
Biochemical and Biophysical Research Communications, 2011, pp.325-329. ⟨10.1016/j.bbrc.2011.08.095⟩
Article dans une revue hal-02905689v1

Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells

Anne-Frédérique Dessein , Laurence Stechly , Nicolas Jonckheere , Patrick Dumont , Didier Monté
Cancer Research, 2010, 70 (11), pp.4644-4654. ⟨10.1158/0008-5472.CAN-09-3828⟩
Article dans une revue hal-02106460v1
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Mucins and Pancreatic Cancer

Nicolas Jonckheere , Nicolas Skrypek , Isabelle van Seuningen
Cancers, 2010, 2, pp.1794-1812. ⟨10.3390/cancers2041794⟩
Article dans une revue inserm-00807873v1
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The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers

Nicolas Jonckheere , Isabelle van Seuningen
Article dans une revue hal-02905696v1

Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression.

Nicolas Jonckheere , Valérie Fauquette , Laurence Stechly , Nathalie Saint-Laurent , Sébastien Aubert
British Journal of Cancer, 2009, 101 (4), pp.637-44. ⟨10.1038/sj.bjc.6605190⟩
Article dans une revue inserm-00410436v1
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Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation

Nicolas Jonckheere , Erin Mayes , Hung-Ping Shih , Boan Li , Oleg Lioubinski
Developmental Biology, 2008, 318 (2), pp.224-235. ⟨10.1016/j.ydbio.2008.03.014⟩
Article dans une revue hal-02954468v1
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The Membrane-Bound Mucins: How Large O-Glycoproteins Play Key Roles in Epithelial Cancers and Hold Promise as Biological Tools for Gene-Based and Immunotherapies

Nicolas Jonckheere , Isabelle Van Seuningen
Critical Review in Oncogenesis, 2008, 14 (2-3), pp.177-196. ⟨10.1615/CritRevOncog.v14.i2-3.30⟩
Article dans une revue hal-02905788v1
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Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1α

Guillaume Piessen , Nicolas Jonckheere , Audrey Vincent , Brigitte Hemon , Marie-Paule Ducourouble
Biochemical Journal, 2007, 402, pp.81 - 91. ⟨10.1042/BJ20061461⟩
Article dans une revue hal-02905759v1
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The Human Mucin MUC4 Is Transcriptionally Regulated by Caudal-related Homeobox, Hepatocyte Nuclear Factors, Forkhead Box A, and GATA Endodermal Transcription Factors in Epithelial Cancer Cells

Nicolas Jonckheere , Audrey Vincent , Michaël Perrais , Marie-Paule Ducourouble , Anita Korteland-van Male
Journal of Biological Chemistry, 2007, ⟨10.1074/jbc.M700905200⟩
Article dans une revue hal-02905844v1
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Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1{alpha}

Guillaume Piessen , Nicolas Jonckheere , Audrey Vincent , Brigitte Hémon , Marie-Paule Ducourouble
Biochemical Journal, 2006, 402 (1), pp.81-91. ⟨10.1042/BJ20061461⟩
Article dans une revue hal-00478670v1

Evidence for a functional genetic polymorphism of the human retinoic acid–metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida

Emmanuel Rat , Ingrid Billaut-Laden , Delphine Allorge , Jean-Marc Lo-Guidice , Marie Tellier
Birth Defects Research Part A: Clinical and Molecular Teratology, 2006, 76 (6), pp.491-498. ⟨10.1002/bdra.20275⟩
Article dans une revue hal-02954484v1

The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells

Valérie Fauquette , Michael Perrais , Sylvain Cerulis , Nicolas Jonckheere , Marie-Paule Ducourouble
Biochemical Journal, 2005, 386 (1), pp.35-45. ⟨10.1042/BJ20040706⟩
Article dans une revue hal-02954487v1
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The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells

Valérie Fauquette , Michael Perrais , Sylvain Cerulis , Nicolas Jonckheere , Marie-Paule Ducourouble
Biochemical Journal, 2005, 386, pp.35 - 45
Article dans une revue hal-02905757v1
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A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-b in pancreatic carcinogenesis

Nicolas Jonckheere , Michael Perrais , Christophe Mariette , Surinder K Batra , Jean-Pierre Aubert
Oncogene, 2004, 23, pp.5729 - 5738. ⟨10.1038/sj.onc.1207769⟩
Article dans une revue hal-02905851v1
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The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells

Maria van Der Sluis , Monique H M Melis , Nicolas Jonckheere , Marie-Paule Ducourouble , Hans A Bü Ller A
Biochemical and Biophysical Research Communications, 2004, 325, pp.952 - 960. ⟨10.1016/j.bbrc.2004.10.108⟩
Article dans une revue hal-02905675v1
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Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-β/Smad4 signalling pathway is potentiated by Sp1

Nicolas Jonckheere , Maria van Der Sluis , Amélie Velghe , Marie-Pierre Buisine , Marjolein Sutmuller
Biochemical Journal, 2004, 377, pp.797 - 808
Article dans une revue hal-02905715v1
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Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway

Michael Perrais , Brigitte Hemon , Isabelle van Seuningen , Christophe Mariette , Michaël Perrais
Biochemical Journal, 2004, 377, pp.701 - 708
Article dans une revue hal-02905748v1

Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway

Christophe Mariette , Michaël Perrais , Emmanuelle Leteurtre , Nicolas Jonckheere , Brigitte Hémon
Biochemical Journal, 2004, 377 (3), pp.701-708. ⟨10.1042/bj20031132⟩
Article dans une revue hal-03314562v1
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Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway

Christophe Mariette , Michael Perrais , Emmanuelle Leteurtre , Nicolas Jonckheere , Brigitte Hemon
Biochemical Journal, 2004, 377, pp.701 - 708
Article dans une revue hal-02905712v1
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Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-β/Smad4 signalling pathway is potentiated by Sp1

Nicolas Jonckheere , Maria van Der Sluis , Amélie Velghe , Marie-Pierre Buisine , Marjolein Sutmuller
Biochemical Journal, 2004, 377, pp.797 - 808. ⟨10.1042/BJ20030948⟩
Article dans une revue hal-02905751v1
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Human MUC2 Mucin Gene Is Transcriptionally Regulated by Cdx Homeodomain Proteins in Gastrointestinal Carcinoma Cell Lines

Patrícia Mesquita , Nicolas Jonckheere , Raquel Almeida , Marie-Paule Ducourouble , Jacinta Serpa
Journal of Biological Chemistry, 2003, ⟨10.1074/jbc.M309019200⟩
Article dans une revue hal-02905842v1

Deciphering and targeting GD2 ganglioside O-Acetylation pathways in neuroectoderm-derived cancers

Angélina Kasprowicz , Sumeyye Cavdarli , Christine Bal , Tiziano Ingegnere , Silvia Gaggero
15èmes Journées scientifiques du Cancéropôle Nord-Ouest (CNO) 2023., 2023, Deauville, France
Poster de conférence hal-04466124v1

Acquisition d’un phénotype myofibroblastique par les cellules stellaires pancréatiques exposées au cadmium.

Mathilde Fourgeaud , Sara Agrane , Océane Dusailly , Sylvie Brassart-Pasco , Julie Auwercx
Club Français du Pancréas, 2023, Lille, France
Poster de conférence hal-04466501v1

Deciphering and targeting GD2 ganglioside O-Acetylation pathways in neuroectoderm-derived cancers

Angélina Kasprowicz , Sumeyye Cavdarli , Christine Bal , Tiziano Ingegnere , Silvia Gaggero
1 st ONCOLille days, Oct 2022, Deauville, France
Poster de conférence hal-04466201v1

Bioinformatics identification of key regulators associated with MUC4 expression in pancreatic adenocarcinoma.

Nicolas Jonckheere , Julie Auwercx , Elsa Hadj Bachir , Lucie Coppin , Audrey Vincent
Mucins in health and Disease, Jul 2022, Utrecht (Netherland), Netherlands
Poster de conférence hal-04465160v1

L’alpha-kinase de TRPM7: comprendre son rôle dans les propriétés invasives de l’adénocarcinome canalaire pancréatique

Julie Auwercx , Alison Vanlaeys , Isabelle Dhennin-Duthille , Philippe Kischel , Frédéric Hague
Journées scientifiques du Cancéropôle Nord-Ouest (CNO) 2022, 2022, Deauville, France
Poster de conférence hal-04465802v1

Abstract 2965: Epigenetic mechanisms involved in acquired resistance to combined chemotherapies in digestive cancer cells

Elsa Hadj Bachir , Charles Poiraud , Hugo Claux , Soumaya El Moghrabi , Sonia Paget
AACR Annual Meeting 2022, 2022, New Orleans (Louisiana), United States. 82 (12_Supplement), pp.2965-2965, 2022, ⟨10.1158/1538-7445.AM2022-2965⟩
Poster de conférence hal-04465616v1

Établissement d’une signature prédictive de la survie globale des patients atteints de cancer colique basée sur le profil d’expression d’enzymes responsables de modifications épigénétiques.

Elsa Hadj Bachir , Bernadette Neve , Guillaum Piessen , Emmanuelle Leteurtre , Florence Renaud
Journées scientifiques du Cancéropôle Nord-Ouest (CNO) 2022, 2022, Deauville, France
Poster de conférence hal-04465808v1

MUC4 interactants: to infinity and beyond.

Nicolas Stoup , Tristan Girgin , Maxime Liberelle , Leila Moum , Nicolas Jonckheere
Mucins in health and Disease, Jul 2022, Utrecht (Netherland), Netherlands
Poster de conférence hal-04465179v1

MAGNESIUM TRANSPORTERS EXPRESSION AND PROGNOSTIC IMPACT IN DIGESTIVE CANCERS

Julie Auwercx , Pierre Rybarczyk , Philippe Kischel , Isabelle Dhennin-Duthille , Denis Chatelain
Future Physiology 2021, Apr 2021, On line conference, United Kingdom
Poster de conférence hal-04465644v1

Abstract LB106: The EGF domains of MUC4 oncomucin interact with ErbB2 and mediate tumorigenic activity of cancer cells represent new potential therapeutic targets

Nicolas Stoup , Maxime Liberelle , Céline Schulz , Romain Vasseur , Romain Magnez
AACR Annual Meeting 2021, 2021, Philadelphia, United States. 81 (13_Supplement), pp.LB106-LB106, 2021, ⟨10.1158/1538-7445.AM2021-LB106⟩
Poster de conférence hal-04465601v1

Expression des transporteurs au magnésium et impact pronostic dans les cancers digestifs.

Julie Auwercx , Pierre Rybarczyk , Philippe Kischel , Isabelle Dhennin-Duthille , Denis Chatelain
Journées scientifiques du Cancéropôle Nord-Ouest (CNO) 2021, 2021, Deauville, France
Poster de conférence hal-04465849v1

Le rôle du domaine kinase de TRPM7 : A la recherche de nouveaux partenaires d’interaction dans l’adénocarcinome canalaire pancréatique.

Julie Auwercx , Alison Vanlaeys , Frédéric Hague , Philippe Kischel , Bernadette Neve
Club Français du Pancréas, 2021, Bron, France
Poster de conférence hal-04465863v1

Pnliprp1 hypermethylation in human exocrine pancreas reveals a link between diabetes and pancreatic cancer

Amna Khamis , Mickael Canouil , Lorella Marselli , Raphaël Boutry , Mara Suleiman
56th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD)., 2020, virtual meeting, United Kingdom
Poster de conférence hal-04465919v1

Evaluation in vitro et in vivo d'une Nouvelle Stratégie d’Immunothérapie ciblant la Galectine-9 dans un modèle de cancer pancréatique.

Alexandre Quilbe , Rami Mustapha , S Renaud , Belinda Duchêne , Clémentine de Schutter
12èmes journées scientifiques du Cancéropôle Nord-Ouest, 2019, Deauville, France
Poster de conférence hal-04466053v1

Roles of the MUC4-miRNA loop in pancreatic carcinogenesis and chemoresistance.

Nihad Boukrout , Fatima Lahdaoui , Céline Schulz , Romain Vasseur , Belinda Duchêne
12èmes journées scientifiques du Cancéropôle Nord-Ouest, 2019, Deauville, France
Poster de conférence hal-04466063v1

Roles of the MUC4-miRNA loop in pancreatic carcinogenesis and chemoresistance.

Nihad Boukrout , Fatima Lahdaoui , Céline Schulz , Romain Vasseur , Belinda Duchêne
11èmes journées scientifiques du Cancéropôle Nord-Ouest, 2018, Deauville, France
Poster de conférence hal-04466077v1

Evaluation of a New Anti-Galectin 9 Immunotherapy Strategy in Pancreatic Cancers.

Alexandre Quilbe , Rami Mustapha , S Renaud , Belinda Duchêne , Clémentine de Schutter
11èmes journées scientifiques du Cancéropôle Nord-Ouest, 2018, Deauville, France
Poster de conférence hal-04466070v1

L’alpha-kinase de TRPM7 : un acteur impliqué dans la migration, l’invasion et la TEM des cellules cancéreuses pancréatiques humaines.

Julie Auwercx , Bernadette Neve , Alison Vanlaeys , Sylvie Brassart-Pasco , Mathilde Fourgeaud
15èmes journées scientifiques du Cancéropôle Nord-Ouest, Deauville, 2023., 2023, Deauville, France
Communication dans un congrès hal-04466150v1

TRPM7 Modulates Human Pancreatic Stellate Cell Activation.

Julie Auwercx , Philippe Kischel , Thibault Lefebvre , Nicolas Jonckheere , Alison Vanlaeys
XVI International Magnesium Symposium (SDRM)., Jun 2022, Glasgow, United Kingdom
Communication dans un congrès hal-04465334v1

In Vitro Study of the Role of TRPM7 Kinase in Metastatic Mechanisms of Pancreatic Cancer Cells.

Julie Auwercx , Alison Vanlaeys , Frédéric Hague , Isabelle Dhennin-Duthille , Philippe Kischel
1 st ONCOLille days, Oct 2022, Lille, France
Communication dans un congrès hal-04466179v1

Magnesium transporters: discovering new potential biomarkers in digestive cancers.

Julie Auwercx , Pierre Rybarczyk , Philippe Kischel , Isabelle Dhennin-Duthille , Denis Chatelain
XV International Magnesium Symposium (SDRM)., Jun 2021, online virtual meeting, United Kingdom
Communication dans un congrès hal-04465355v1

Evaluation of a New Anti-Galectin 9 Immunotherapy Strategy in Pancreatic Cancers.

Alexandre Quilbe , Rami Mustapha , Belinda Duchêne , S Renaud , Clémentine de Schutter
Club Français du Pancréas, 2019, Bron, France
Communication dans un congrès hal-04465692v1

Roles of MUC4-miR-210 in pancreatic carcinogenesis and Chemotherapy resistance.

Nihad Boukrout , Fatima Lahdaoui , Céline Schulz , Romain Vasseur , Belinda Duchêne
Mucins in health and disease (15th International Workshop on Carcinoma-associated Mucins), 2019, Cambridge, United Kingdom
Communication dans un congrès hal-04465368v1

Evaluation of a New Anti-Galectin 9 Immunotherapy Strategy in Pancreatic Cancers

Alexandre Quilbe , Rami Mustapha , S Renaud , Belinda Duchêne , Clémentine de Schutter
4ème Journée Scientifique de l’Association pour la Recherche sur le Cancer du pancréas (AFRCP), 2018, Clichy, France
Communication dans un congrès hal-04465715v1

Evaluation of a New Anti-Galectin 9 Immunotherapy Strategy in Pancreatic Cancers

Alexandre Quilbe , Rami Mustapha , S Renaud , Belinda Duchêne , Clémentine de Schutter
11èmes journées scientifiques du Cancéropole Nord Ouest, 2018, Deauville, France
Communication dans un congrès hal-04465768v1

Evaluation of a New Anti-Galectin 9 Immunotherapy Strategy in Pancreatic Cancers

Alexandre Quilbe , Rami Mustapha , S Renaud , Belinda Duchêne , Clémentine de Schutter
5th European Congress of Immunology, 2018, Amsterdam, Netherlands
Communication dans un congrès hal-04465749v1

Strategy of inhibition of TRPM7 channel in pancreatic cancer cells by CRISPR/Cas9.

Alison Vanlaeys , Bernadette Neve , Mouloud Souidi , Isabelle van Seuningen , Halima Ouadid-Ahidouch
4ème Journée Scientifique de l’Association pour la Recherche sur le Cancer du pancréas (AFRCP), 2018, Clichy, France
Communication dans un congrès hal-04465699v1

The MUC4 membrane-bound mucin mediates FOLFIRINOX drugs resistance of human pancreatic cancer cells.

Nicolas Skrypek , Luc Kotzmann , Romain Vasseur , Fatima Lahdaoui , Belinda Duchêne
Mucins in health and disease (13th International Workshop on Carcinoma-associated Mucins), 2015, Cambridge, United Kingdom
Communication dans un congrès hal-04465781v1