Nicolas SAVY

Olivier Catteau, Anne Mayère, Nicolas Savy, Odile Beyne-Rauzy. Équiper et évaluer un « certificat de compétences cliniques ». STICEF (Sciences et Technologies de l'Information et de la Communication pour l'Éducation et la Formation), ATIEF, 2021, Numéro Spécial - Sélection de la conférence EIAH 2019, 27 (2), pp.1-28. ⟨10.23709/sticef.27.2.1⟩. ⟨hal-03186732⟩

Loic Bethencourt, Walid Dabachine, Vincent Dejouy, Zakaria Lalmiche, Karl Neuberger, et al.. Guiding measurement protocols of connected medical devices using digital twins: A statistical methodology applied to detecting and monitoring lymphedema. IEEE Access, IEEE, 2021, Online ahead of print. ⟨10.1109/ACCESS.2021.3063786⟩. ⟨inserm-03167145⟩

Nicolas Savy, Anne Mayère, Anja Martin-Scholz, François Lambotte. La fabrique des données à l’épreuve des programmes de big data. Actualité et dossier en santé publique, la Documentation française, 2020, Dossier thématique Données massives et santé publique, pp.27-29. ⟨hal-03352270⟩

Valérie Garès, Chloé Dimeglio, Grégory Guernec, Romain Fantin, Benoit Lepage, et al.. On the use of optimal transportation theory to recode variables and application to database merging. International Journal of Biostatistics, De Gruyter, 2020, 16 (1), pp.article number : 20180106. ⟨10.1515/ijb-2018-0106⟩. ⟨hal-01905857v2⟩

Michael Mounié, Nadège Costa, Cécile Conte, Dominique Petiot, Didier Fabre, et al.. Real-world costs of illness of Hodgkin and the main B-Cell Non-Hodgkin lymphomas in France. Journal of Medical Economics, Taylor & Francis, 2020, 23 (3), pp.235-242. ⟨10.1080/13696998.2019.1702990⟩. ⟨hal-02533775⟩

Xavier Coumoul, Rémi Servien, Ludmila Juricek, yael Kaddouch-Amar, yannick Lippi, et al.. The GMO90+ Project: Absence of Evidence for Biologically Meaningful Effects of Genetically Modified Maize-based Diets on Wistar Rats After 6-Months Feeding Comparative Trial. Toxicological Sciences, Oxford University Press (OUP), 2019, 168 (2), pp.315-338. ⟨10.1093/toxsci/kfy298⟩. ⟨hal-02196332⟩

Hélène Charbonneau, Marie Pasquié, Benoit Peyronnet, Aurélien Descazeaud, Nicolas Barry-Delongchamps, et al.. Stopping or maintaining oral anticoagulation in patients undergoing photoselective vaporization of the prostate (SOAP) surgery for benign prostate obstruction: study protocol for a multicentre randomized controlled trial. Trials, BioMed Central, 2018, 19 (1), ⟨10.1186/s13063-018-3066-9⟩. ⟨hal-02180512⟩

Michael Mounié, Nadège Costa, Martin Gauthier, Aurore Palmaro, Cyrille Delpierre, et al.. Évaluation du coût de la prise en charge des patients atteints de Leucémie Myéloïde Chronique (LMC) en Midi-Pyrénées : impact économique des différents Inhibiteurs de Protéines Kinases. Journal de gestion et d’économie médicales, Editions ESKA, 2018, 36 (2), pp.109. ⟨hal-01976692⟩

Michael Mounié, Nadège Costa, Laurent Sailler, Maryse Lapeyre-Mestre, Robert Bourrel, et al.. Incremental Costs in Giant Cell Arteritis. Arthritis Care & Research = Arthritis Care and Research, Wiley-Blackwell, 2018, 70 (7), pp.1074 - 1081. ⟨10.1002/acr.23429⟩. ⟨hal-01864221⟩

Nicolas Savy, Josep Vives. Anticipative Integrals with respect to a filtered Lévy Process and Lévy-Itô decomposition. Communications on Stochastic Analysis, 2017, 11 (1), pp.63-85. ⟨hal-01864321⟩

Nathan Minois, Valerie Lauwers-Cances, Stephanie Savy, Michel Attal, Sandrine Andrieu, et al.. Using Poisson-gamma model to evaluate the duration of recruitment process when historical trials are available. Statistics in Medicine, Wiley-Blackwell, 2017, 36 (23), pp.3605 - 3620. ⟨10.1002/sim.7365⟩. ⟨hal-01864244⟩

Nathan Minois, Valerie Lauwers-Cances, Stephanie Savy, Michel Attal, Sandrine Andrieu, et al.. How to deal with the Poisson-gamma model to forecast patients' recruitment in clinical trials when there are pauses in recruitment dynamic?. Contemporary Clinical Trials Communications, Elsevier, 2017, 5 (23), pp.144 - 152. ⟨10.1016/j.conctc.2017.01.003⟩. ⟨hal-01864356⟩

Caroline Hurault-Delarue, Cécile Chouquet, Nicolas Savy, Isabelle Lacroix, Anna-Belle Beau, et al.. Interest of the trajectory method for the evaluation of outcomes after in utero drug exposure: example of anxiolytics and hypnotics. Pharmacoepidemiology and Drug Safety, Wiley, 2017, 26 (5), pp.561-569. ⟨hal-01974892⟩

Benoit Lepage, Sébastien Lamy, Nicolas Savy, Thierry Lang. The Authors Respond. Epidemiology, Lippincott, Williams & Wilkins, 2017, 28 (3), pp.e29. ⟨10.1097/EDE.0000000000000619⟩. ⟨hal-01864253⟩

Valérie Garès, Sandrine Andrieu, Jean-François Dupuy, Nicolas Savy. On the Fleming-Harrington test for late effects in prevention randomized controlled trials. Journal of Statistical Theory and Practice, Grace Scientific Pub., 2017, 11 (3), pp.418-435. ⟨10.1080/15598608.2017.1295889⟩. ⟨hal-01539213⟩

Caroline Hurault-Delarue, Cécile Chouquet, Nicolas Savy, Isabelle Lacroix, Anna-Belle Beau, et al.. How to take into account exposure to drugs over time in pharmacoepidemiology studies of pregnant women?. Pharmacoepidemiology and Drug Safety, Wiley, 2016, 25 (7), pp.770 - 777. ⟨10.1002/pds.4000⟩. ⟨hal-01864258⟩

Benoit Lepage, Dominique Dedieu, Nicolas Savy, Thierry Lang. Estimation of a controlled direct effect when an effect of the exposure confounds the mediator-outcome relationship: a comparison of different methods.. Statistical Methods in Medical Research, SAGE Publications, 2016, 25 (2), pp.553-570. ⟨hal-01864366⟩

Françoise Lainé, Nicolas Savy. Un vicomte rescapé, un comte retrouvé et un chevalier ruiné. Notes sur des prisonniers de la bataille de Poitiers. Annales du Midi : revue archéologique, historique et philologique de la France méridionale, Editions Privat, 2016, 128 (293), pp.45-67. ⟨hal-01477735⟩

Michael Mounié, Grégory Pugnet, Nicolas Savy, Maryse Lapeyre-Mestre, Laurent Molinier, et al.. Additional costs of polymyalgia rheumatica with giant-cell arteritis. Arthritis Care & Research = Arthritis Care and Research, Wiley-Blackwell, 2016, 11 (3), pp.418-435. ⟨hal-01976676⟩

Benoit Lepage, Sébastien Lamy, Dominique Dedieu, Nicolas Savy, Thierry Lang. Estimating the Causal Effect of an Exposure on Change from Baseline Using Directed Acyclic Graphs and Path Analysis. Epidemiology, Lippincott, Williams & Wilkins, 2015, 26 (1), pp.122 - 129. ⟨10.1097/EDE.0000000000000192⟩. ⟨hal-01864260⟩

Valérie Garès, Sandrine Andrieu, Jean-François Dupuy, Nicolas Savy. An omnibus test for several hazard alternatives in prevention randomized controlled clinical trials. Statistics in Medicine, Wiley-Blackwell, 2015, 34 (4), pp.541-557. ⟨10.1002/sim.6366⟩. ⟨hal-01120983⟩

Chloé Dimeglio, Cyrille Delpierre, Nicolas Savy, Thierry Lang. Big Data et Santé publique : plus que jamais, les enjeux de la connaissance. Actualité et dossier en santé publique, la Documentation française, 2015, 93, pp.5-7. ⟨hal-01864348⟩

Alice Aarnink, Edward Mee, Nicolas Savy, Nicola Congy-Jolivet, Nicola Rose, et al.. Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model. Immunogenetics, Springer Verlag, In press, 66 (2), pp.105 - 113. ⟨10.1007/s00251-013-0752-3⟩. ⟨hal-01864282⟩

Dominique Dedieu, Cyrille Delpierre, Sébastien Gadat, Thierry Lang, Benoit Lepage, et al.. Mixed Hidden Markov Model for Heterogeneous Longitudinal Data with Missingness and Errors in the Outcome Variable. Journal de la Société Française de Statistique, Société Française de Statistique et Société Mathématique de France, 2014, 105 (1), pp.73-98. ⟨hal-01864353⟩

Valérie Garès, Sandrine Andrieu, Jean-François Dupuy, Nicolas Savy. A comparison of the constant piecewise weighted logrank and Fleming-Harrington tests. Electronic Journal of Statistics , Shaker Heights, OH : Institute of Mathematical Statistics, 2014, 8, pp.841-860. ⟨10.2014/14-EJS911⟩. ⟨hal-01056360⟩

Bernard Bercu, Frédéric Proïa, Nicolas Savy. On Ornstein-Uhlenbeck driven by Ornstein-Uhlenbeck processes. Statistics and Probability Letters, Elsevier, 2014, 85, pp.36-44. ⟨10.1016/j.spl.2013.11.002⟩. ⟨hal-00915963⟩

Antoine Blancher, Alice Aarnink, Nicolas Savy, Naoyuki Takahata. Use of Cumulative Poisson Probability Distribution as an Estimator of the Recombination Rate in an Expanding Population: Example of the Macaca fascicularis Major Histocompatibility Complex. G3, Genetics Society of America, 2012, 2, pp.123-130. ⟨10.1534/g3.111.001248⟩. ⟨hal-01864345⟩

Bernard Bercu, Laure Coutin, Nicolas Savy. Sharp large deviations for the non-stationary Ornstein-Uhlenbeck process. Stochastic Processes and their Applications, Elsevier, 2012, 122, pp.3393-3424. ⟨10.1016/j.spa.2012.06.006⟩. ⟨hal-00645074⟩

Alexander Alvarez, Fabien Panloup, Monique Pontier, Nicolas Savy. Estimation of the instantaneous volatility. Statistical Inference for Stochastic Processes, Springer Verlag, 2012, 15 (1), pp.27-59. ⟨10.1007/s11203-011-9062-2⟩. ⟨hal-00761710⟩

Guillaume Mijoule, Stéphanie Savy, Nicolas Savy. Models for patients' recruitment in clinical trials and sensitivity analysis. Statistics in Medicine, Wiley-Blackwell, 2012, 31 (16), pp.1655-1674. ⟨10.1002/sim.4495⟩. ⟨hal-00942867⟩

Bernard Bercu, Laure Coutin, Nicolas Savy. Sharp large deviations for the fractional Ornstein-Uhlenbeck process. SIAM Theory of Probability and its Applications, Society for Industrial and Applied Mathematics, 2011, 55 (4), pp.575-610. ⟨hal-00386239⟩

Laurent Decreusefond, Aldéric Joulin, Nicolas Savy. Upper bounds on Rubinstein distances on configuration spaces and applications. Communications on Stochastic Analysis, 2010, 4 (3), pp.377--399. ⟨hal-00347899v2⟩

Bernard Bercu, Laure Coutin, Nicolas Savy. Sharp large deviations for the fractional Ornstein - Uhlenbeck process. Teoriya Veroyatnostei i ee Primeneniya, Steklov Mathematical Institute of Russian Academy of Sciences, 2010, 55 (4), pp.732-771. ⟨hal-01976746⟩

L. Decreusefond, Nicolas Savy. Anticipative calculus with respect to filtered Poisson processes. Annales de l'Institut Henri Poincaré (B) Probabilités et Statistiques, Institut Henri Poincaré (IHP), 2006, 42 (3), pp.343 - 372. ⟨10.1016/j.anihpb.2005.03.005⟩. ⟨hal-01864331⟩

Louis Coroller, Ivan Leguérinel, Eric Mettler, Nicolas Savy, Pierre Mafart. A general model based on two mixed Weibull distributions of bacterial resistance, for fitting various shapes of inactivation curves. Applied and Environmental Microbiology, American Society for Microbiology, 2006, 72 (10), pp.6493-6502. ⟨10.1128/AEM.00876-06⟩. ⟨hal-00552093⟩

Stéphane Gaillard, Ivan Leguérinel, Nicolas Savy, Pierre Mafart. Quantifying the combined effects of the heating time, the temperature and the recovery medium pH on the regrowth lag time of Bacillus cereus spores after a heat treatment. International Journal of Food Microbiology, Elsevier, 2005, pp.1-6. ⟨hal-00653930⟩

Laurent Decreusefond, Nicolas Savy. Filtered Brownian motions as weak limit of filtered Poisson processes. Bernoulli, Bernoulli Society for Mathematical Statistics and Probability, 2005, 11 (2), pp.283-292. ⟨hal-01864326⟩

Olivier Couvert, Stéphane Gaillard, Nicolas Savy, Pierre Mafart, Ivan Leguérinel. Survival curves of heated bacterial spores: effect of environmental factors on Weibull parameters. International Journal of Food Microbiology, Elsevier, 2005, 101 (1), pp.73-81. ⟨10.1016/j.ijfoodmicro.2004.10.048⟩. ⟨hal-00560873⟩

L. Decreusefond, Nicolas Savy. Filtered Brownian motions as weak limit of filtered Poisson processes. Bernoulli, Bernoulli Society for Mathematical Statistics and Probability, 2005, 11 (2), pp.283-292. ⟨hal-00841352⟩

Anja Martin-Scholz, Nicolas Savy, Anne Mayère, François Lambotte. Causality put to the test of the big data movement: a communicational approach. Journées du club SMAC – Statistics, Philosophy and Health, Jun 2021, Toulouse, France. ⟨hal-03352315⟩

Olivier Catteau, Odile Beyne Rauzy, Anne Mayère, Nicolas Savy. Dispositif d'évaluation pour un certificat d'aptitudes cliniques : quelles mesures pour quelles compétences ?. 9e Conference Environnements Informatiques pour l'Apprentissage Humain (EIAH 2019), Jun 2019, Paris, France. pp.157-168. ⟨hal-02435357⟩

Nathan Minois, Guillaume Mijoule, Stéphanie Savy, Valérie Lauwers-Cances, Sandrine Andrieu, et al.. Performances of Poisson–Gamma Model for Patients’ Recruitment in Clinical Trials When There Are Pauses in Recruitment or When the Number of Centres is Small. Springer Proceedings in Mathematics & Statistics book series - Statistics and Simulation - IWS 8, Vienna, Austria, September 2015, 2015. ⟨hal-01976829⟩

Nicolas Savy, Stéphanie Savy, Sandrine Andrieu, Sebastien Marque. Simulated Clinical Trials: Principle, Good Practices, and Focus on Virtual Patients Generation. Springer Proceedings in Mathematics & Statistics book series - statistics and simulation - IWS 8, Vienna, Austria, September 2015, 2015. ⟨hal-01976838⟩

Guillaume Mijoule, Nathan Minois, Vladimir Anisimov, Nicolas Savy. Additive Cost Modelling in Clinical Trial. Springer Proceedings in Mathematics & Statistics book series (PROMS, volume 114) -, 2014. ⟨hal-01976846⟩

Nicolas Savy. Mouvement Brownien Fractionnaire, applications aux télécommunications. Calcul Stochastique relativement à des processus fractionnaires.. Mathématiques [math]. Université Rennes 1, 2003. Français. ⟨tel-00003407⟩

Nicolas Savy. Investigations on Stochastic Calculus, Statistics of Processes Applied Statistics for Biology and Medical Research . Applications [stat.AP]. Université de Toulouse 3 Paul Sabatier, 2014. ⟨tel-01645597⟩